How does neurogenesis in the adult hippocampus influence learning & memory? (2015-2018)
Abstract
One of the primary brain structures critical for learning and memory in animals and humans is the hippocampus, where regulated production of new neurons throughout life (i.e. adult neurogenesis) underpins these cognitive functions. The proposed research will unravel how adult-born neurons exert their influence over behaviour by determining when newly born neurons become critical for behaviour and the connections made by these cells within the hippocampal network. It will provide fundamental new insight into the stages at which these neurons are important for the acquisition of spatial task versus the recall of spatial tasks.