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2024

Conference Publication

Epithelial cancers demonstrate IL34-associated dysfunction of Langerhans cells

Dang, Thi Viet Trinh, Gillinder, Kevin R., Nguyen, Quan, Mulay, Onkar, Vo, Tuan, Mehdi, Ahmed M., Zhou, Chenhao, Brooks, Andrew J., Asplett, Kiran, Leggatt, Graham R., Hume, David A., Frazer, Ian H. and Chandra, Janin (2024). Epithelial cancers demonstrate IL34-associated dysfunction of Langerhans cells. AACR Special Conference in Cancer Research: Tumor Immunology and Immunotherapy, Boston, MA, United States, 18-21 October 2024. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/2326-6074.tumimm24-a001

Epithelial cancers demonstrate IL34-associated dysfunction of Langerhans cells

2022

Conference Publication

Gene-therapy based modulation of antigen-presenting cells within hyperproliferative epithelium to restore immunity

Dang, T. V. T., Gillinder, K. G., Brooks, A. J., Asplett, K., Tolley, L. K., Hume, D. A., Leggatt, G. R., Frazer, I. H. and Chandra, J. (2022). Gene-therapy based modulation of antigen-presenting cells within hyperproliferative epithelium to restore immunity. 29th Annual Congress of the European-Society-of-Gene-and-Cell-Therapy (ESCGT), Edinburgh, United Kingdom, 11-14 October 2022. New Rochelle, NY United States: Mary Ann Liebert.

Gene-therapy based modulation of antigen-presenting cells within hyperproliferative epithelium to restore immunity

2019

Conference Publication

Specific domains of LNK (SH2B3) bind and regulate TPOR stability and signalling

Lee, Christine, Brooks, Andrew, Chhabra, Yash and Perkins, Andrew (2019). Specific domains of LNK (SH2B3) bind and regulate TPOR stability and signalling. 48th Annual Scientific Meeting of the Society for Experimental Hematology, Brisbane, Australia, 22-25 August 2019. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2019.06.387

Specific domains of LNK (SH2B3) bind and regulate TPOR stability and signalling

2019

Conference Publication

The mechanism of oncogenic mutations in the juxtamembrane and transmembrane region of IL7RA and TPOR/MPL

Brooks, Andrew, Campos, Livia, Lee, Christine, Chhabra, Yash, Bridgford, Jessica, Lee, Su Min, Zenatti, Priscila, Pissinato, Leonardo, Rodrigues, Gisele, Artico, Leonardo, Guimarães, Thais, Archangelo, Leticia, Martínez, Leandro, Slape, Christopher, Call, Matthew, Call, Melissa and Yunes, José (2019). The mechanism of oncogenic mutations in the juxtamembrane and transmembrane region of IL7RA and TPOR/MPL. ISEH 2019, Brisbane, Australia, 22-25 August 2019. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2019.06.332

The mechanism of oncogenic mutations in the juxtamembrane and transmembrane region of IL7RA and TPOR/MPL

2017

Conference Publication

Class I cytokine receptors: towards the inside

Steinocher, Helena, Bugge, Katrine, Nikolajsen, Louise Fletcher, Lindorff-Larsen, Kresten, Brooks, Andrew and Kragelund, Birthe Brandt (2017). Class I cytokine receptors: towards the inside. 61st Annual meeting of the Biophysical Society, New Orleans, LA, United States, 11-15 February 2017. St. Louis, MO United States: Cell Press. doi: 10.1016/j.bpj.2016.11.947

Class I cytokine receptors: towards the inside

2016

Conference Publication

Going downstream - how does GH binding activate JAK2

Brooks, Andrew, Dai, W., O'Mara, M. L., Abankwa, D., Chhabra, Y., Pelekanos, R. A., Gardon, O., Tunny, K. A., Blucher, K. M., Morton, C. J., Parker, M. W., Sierecki, E., Gambin, Y., Gomez, G. A., Alexandrov, K., Wilson, I. A., Doxastakis, M., Mark, A. E. and Waters, M. J. (2016). Going downstream - how does GH binding activate JAK2. Annual Scientific Meeting of the Endocrine Society of Australia, Adelaide, Australia, 23-26 August, 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/cen.13010

Going downstream - how does GH binding activate JAK2

2016

Conference Publication

Mechanism of JAK2 Activation by the Archetype Class I Cytokine Receptor, the Growth Hormone Receptor

Brooks, Andrew J., O’Mara, Megan L., Dai, Wei, Abankwa, Daniel, Chhabra, Yash, Tunny, Kathryn A., Parker, Michael W., Sierecki, Emma, Gambin, Yann, Gomez, Guillermo A., Haxholm, Gitte W., Nikolajsen, Louise F., Doxastakis, Manolis, Mark, Alan E. and Waters, Michael J. (2016). Mechanism of JAK2 Activation by the Archetype Class I Cytokine Receptor, the Growth Hormone Receptor. Biophysical Meeting, Los Angeles, CA, United States, 27 February - 2 March 2016. CAMBRIDGE: CELL PRESS. doi: 10.1016/j.bpj.2015.11.233

Mechanism of JAK2 Activation by the Archetype Class I Cytokine Receptor, the Growth Hormone Receptor

2015

Conference Publication

A potential role for Janus protein tyrosine kinases in the regulation of epithelial-mesenchymal transition in a model of epidermal growth factor induced breast cancer epithelial-mesenchymal transition

Stewart, Teneale A., Azimi, Iman, Davis, Felicity M., Thompson, Erik W., Brooks, Andrew J., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2015). A potential role for Janus protein tyrosine kinases in the regulation of epithelial-mesenchymal transition in a model of epidermal growth factor induced breast cancer epithelial-mesenchymal transition. 37th Annual CTRC-AACR San Antonio Breast Cancer Symposium, San Antonio, TX United States, 9-13 December 2014. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS14-P2-07-05

A potential role for Janus protein tyrosine kinases in the regulation of epithelial-mesenchymal transition in a model of epidermal growth factor induced breast cancer epithelial-mesenchymal transition

2014

Conference Publication

Mechanism of activation of JAK2 by growth hormone

Waters, M. J. and Brooks, A. J. (2014). Mechanism of activation of JAK2 by growth hormone. Seventh International Congress of the GRS and the IGF Society, Singapore, 17-20 October 2014. London, United Kingdom: Churchill Livingstone. doi: 10.1016/S1096-6374(14)50035-4

Mechanism of activation of JAK2 by growth hormone

2014

Conference Publication

A new cytokine receptor activation paradigm: Activation of JAK2 by the growth hormone receptor

Brooks, Andrew J, Chhabra, Yash, Abankwa, Daniel, O’Mara, Megan, Dai, Wei, Gardon, Olivier, Tunny, Kathryn A., Blucher, Kristopher M., Morton, Craig J., Parker, Michael W., Sierecki, Emma, Gambin, Yann, Guillermo A. Gomez, Alexandrov, Kirill Kirill, Doxastakis, Manolis, Mark, Alan E. and Waters, Michael J. (2014). A new cytokine receptor activation paradigm: Activation of JAK2 by the growth hormone receptor. 2nd Annual Meeting of the International Cytokine and Interferon Society (ICIS), Melbourne, VIC Australia, 26 - 29 October 2014. London, United Kingdom: Academic Press. doi: 10.1016/j.cyto.2014.07.227

A new cytokine receptor activation paradigm: Activation of JAK2 by the growth hormone receptor

2014

Conference Publication

The first cancer-associated variant of the growth hormone receptor

Chhabra, Yash, Wong, Ho Yi, Brooks, Andrew James and Waters, Michael John (2014). The first cancer-associated variant of the growth hormone receptor. Endocrine Society's 96th Annual Meeting and Expo, Chicago, IL, United States, 21-24 June 2014. WASHINGTON: Endocrine Society.

The first cancer-associated variant of the growth hormone receptor

2014

Conference Publication

Assessment of Janus protein tyrosine kinases as potential regulators of epithelial-mesenchymal transition using a model of epidermal growth factor induced breast cancer epithelial-mesenchymal transition

Bassett, John J., Stewart, Teneale A., Azimi, Iman , Davis, Felicity M., Thompson, Erik W., Brooks, Andrew J., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2014). Assessment of Janus protein tyrosine kinases as potential regulators of epithelial-mesenchymal transition using a model of epidermal growth factor induced breast cancer epithelial-mesenchymal transition. ASCEPT-MPGPCR Joint Scientific Meeting, Melbourne, VIC Australia, 7-11 December 2014.

Assessment of Janus protein tyrosine kinases as potential regulators of epithelial-mesenchymal transition using a model of epidermal growth factor induced breast cancer epithelial-mesenchymal transition

2012

Conference Publication

Hepatic IGF-I production is regulated by Kupffer cells

Ishikawa, M., Barclay, J. L., Brooks, A. J., McPhee, T. R., Yoshino, G. and Waters, M. J. (2012). Hepatic IGF-I production is regulated by Kupffer cells. Sixth International Congress of the GRS and the IGF Society, Munich, Germany, 17-20 October 2012. London, United Kingdom: Churchill Livingstone. doi: 10.1016/S1096-6374(12)60056-2

Hepatic IGF-I production is regulated by Kupffer cells

2012

Conference Publication

Growth hormone and cell growth

Waters, Michael J. and Brooks, Andrew J. (2012). Growth hormone and cell growth. 6th ESPE Advanced Seminar in Developmental Endocrinology, Bern, Switzerland, 10-11 May 2012. Basel, Switzerland: S. Karger. doi: 10.1159/000341761

Growth hormone and cell growth

2011

Conference Publication

Growth hormone receptor: structure function relationships

Waters, Michael J. and Brooks, Andrew J. (2011). Growth hormone receptor: structure function relationships. Switzerland: S. Karger AG. doi: 10.1159/000329138

Growth hormone receptor: structure function relationships

2010

Conference Publication

Role of growth hormone signaling pathways in liver regeneration

Ishikawa, M., McPhee, T. R., Barclay, J. L., Fernandez-Rojo, M., Brooks, A. J. and Waters, M. J. (2010). Role of growth hormone signaling pathways in liver regeneration. Fifth International congress of the GRS and the IGF Society, New York, NY, United States, 3-7 October. London, United Kingdom: Churchill Livingstone. doi: 10.1016/S1096-6374(10)70011-3

Role of growth hormone signaling pathways in liver regeneration