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2011

Journal Article

Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA1c levels in human pancreatic islets

Yang, B. T., Dayeh, T. A., Kirkpatrick, C. L., Taneera, J., Kumar, R., Groop, L., Wollheim, C. B., Nitert, M. D. and Ling, C. (2011). Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA1c levels in human pancreatic islets. Diabetologia, 54 (2), 360-367. doi: 10.1007/s00125-010-1967-6

Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA1c levels in human pancreatic islets

2011

Journal Article

A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes

Koeck, Thomas, Olsson, Anders H., Nitert, Marloes Dekker, Sharoyko, Vladimir V., Ladenvall, Claes, Kotova, Olga, Reiling, Erwin, Ronn, Tina, Parikh, Hemang, Taneera, Jalal, Eriksson, Johan G., Metodiev, Metodi D., Larsson, Nils-Goran, Balhuizen, Alexander, Luthman, Holger, Stancakova, Alena, Kuusisto, Johanna, Laakso, Markku, Poulsen, Pernille, Vaag, Allan, Groop, Leif, Lyssenko, Valeriya, Mulder, Hindrik and Ling, Charlotte (2011). A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes. Cell Metabolism, 13 (1), 80-91. doi: 10.1016/j.cmet.2010.12.007

A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes

2011

Book Chapter

Epigenetics and type 2 diabetes

Ling, Charlotte, Ronn, Tina and Nitert, Marloes Dekker (2011). Epigenetics and type 2 diabetes. Epigenetic aspects of chronic diseases. (pp. 135-145) edited by Helmtrud I. Roach, Felix Bronner and Richard O.C. Oreffo. London, United Kingdom: Springer. doi: 10.1007/978-1-84882-644-1_9

Epigenetics and type 2 diabetes

2010

Journal Article

Apelin is a novel islet peptide

Ringstrom, Camilla, Nitert, Marloes Dekker, Bennet, Hedvig, Fex, Malin, Valet, Phillipe, Rehfeld, Jens F., Friis-Hansen, Lennart and Wierup, Nils (2010). Apelin is a novel islet peptide. Regulatory Peptides, 162 (1-3), 44-51. doi: 10.1016/j.regpep.2010.03.005

Apelin is a novel islet peptide

2010

Conference Publication

Risk genotypes, allele-specific expression and methylation status in human islets at the KCNQ1 type 2 diabetes-susceptibility locus

Travers, M. E., Nitert, M. D., Mackay, D. J. G., Lindgren, C. M., Groop, L., Gloyn, A. L. and McCarthy, M. I. (2010). Risk genotypes, allele-specific expression and methylation status in human islets at the KCNQ1 type 2 diabetes-susceptibility locus. 46th Annual Meeting of the European Association for the Study of Diabetes (EASD), Stockholm, Sweden, 20-24 September 2010. Springer.

Risk genotypes, allele-specific expression and methylation status in human islets at the KCNQ1 type 2 diabetes-susceptibility locus

2010

Conference Publication

Stimulation of 5-HT1a receptor decreased insulin secretion in islets of Langerhans from mice and humans

Bennet, H., Nagorny, C. L. F., Wierup, N., Dekker-Nitert, M., Lernmark, A. and Fex, M. (2010). Stimulation of 5-HT1a receptor decreased insulin secretion in islets of Langerhans from mice and humans. 46th Annual Meeting of the European Association for the Study of Diabetes (EASD), Stockholm, Sweden, 20-24 September 2010. Springer.

Stimulation of 5-HT1a receptor decreased insulin secretion in islets of Langerhans from mice and humans

2010

Conference Publication

Resistance to exercise-induced changes in the global DNA methylation pattern of skeletal muscle in individuals with a family history of type 2 diabetes

Nitert, M. D., Dayeh, T., Lang, S., Elgzyri, T., Yang, B., Hansson, O., Ronn, T., Eriksson, K. F., Groop, L. and Ling, C. (2010). Resistance to exercise-induced changes in the global DNA methylation pattern of skeletal muscle in individuals with a family history of type 2 diabetes. 46th Annual Meeting of the European Association for the Study of Diabetes (EASD), Stockholm, Sweden, 20-24 September 2010. Springer.

Resistance to exercise-induced changes in the global DNA methylation pattern of skeletal muscle in individuals with a family history of type 2 diabetes

2010

Conference Publication

Nesfatin-1 stimulates insulin secretion, inhibits glucagon secretion and is expressed in human and rodent beta cells

Voss, U., Riva, M., Dekker Nitert, M. N., Ling, C., Lindqvist, A. and Wierup, N. (2010). Nesfatin-1 stimulates insulin secretion, inhibits glucagon secretion and is expressed in human and rodent beta cells. 46th Annual Meeting of the European Association for the Study of Diabetes (EASD), Stockholm, Sweden, 20-24 September 2010. Heidelberg, Germany: Springer. doi: 10.1007/s00125-010-1872-z

Nesfatin-1 stimulates insulin secretion, inhibits glucagon secretion and is expressed in human and rodent beta cells

2010

Conference Publication

Apelin is expressed in human and rodent islets and regulates insulin secretion

Ringstrom, Camilla, Nitert, Marloes Dekker, Bennet, Hedvig, Fex, Malin, Valet, Philippe, Rehfeld, Jens F., Friis-Hansen, Lennart and Wierup, Nils (2010). Apelin is expressed in human and rodent islets and regulates insulin secretion. 18th International Symposium on Regulatory Peptides, Belfast, United Kingdom, 5 - 8 September 2010. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.regpep.2010.07.059

Apelin is expressed in human and rodent islets and regulates insulin secretion

2010

Conference Publication

A lipotoxicity model in the INS-1 832/13 beta cell line and the epigenetic alterations induced by it

Malmgren, S., Sharoyko, V. V., Nicholls, D. G., Nagorny, C. L. F., Spegel, P., Nitert, M. D., Mulder, H. and Ling, C. (2010). A lipotoxicity model in the INS-1 832/13 beta cell line and the epigenetic alterations induced by it. 46th Annual Meeting of the European Association for the Study-of-Diabetes (EASD), Stockholm, Sweden, 20-24 September 2010. Heidelberg, Germany: Springer. doi: 10.1007/s00125-010-1872-z

A lipotoxicity model in the INS-1 832/13 beta cell line and the epigenetic alterations induced by it

2009

Journal Article

A beta cell-specific knockout of hormone-sensitive lipase in mice results in hyperglycaemia and disruption of exocytosis

Fex, M., Haemmerle, G., Wierup, N., Dekker-Nitert, M., Rehn, M., Ristow, M., Zechner, R., Sundler, F., Holm, C., Eliasson, L. and Mulder, H. (2009). A beta cell-specific knockout of hormone-sensitive lipase in mice results in hyperglycaemia and disruption of exocytosis. Diabetologia, 52 (2), 271-280. doi: 10.1007/s00125-008-1191-9

A beta cell-specific knockout of hormone-sensitive lipase in mice results in hyperglycaemia and disruption of exocytosis

2009

Conference Publication

Disruption of TFB1M impairs insulin secretion in beta cells

Kock, T., Nitert, M. D., Olsson, A., Kotova, O., Stamenkovic, J., Lyssenko, V., Groop, L., Luthman, H., Ling, C. and Mulder, H. (2009). Disruption of TFB1M impairs insulin secretion in beta cells. 45th Annual Meeting of the European Association for the Study of Diabetes, Vienna, Austria, 30 September - 2 October 2009. Springer.

Disruption of TFB1M impairs insulin secretion in beta cells

2009

Conference Publication

5-hydroxytryptamine exposure stimulates insulin secretion in clonal beta cells but not in islets of Langerhans

Fex, M., Bennet, H., Nagorny, C., Nitert, M. D., Wierup, N. and Lernmark, A. (2009). 5-hydroxytryptamine exposure stimulates insulin secretion in clonal beta cells but not in islets of Langerhans. 45th Annual Meeting of the European Association for the Study of Diabetes, Vienna, Austria, 30 September - 2 October 2009. Springer.

5-hydroxytryptamine exposure stimulates insulin secretion in clonal beta cells but not in islets of Langerhans

2008

Journal Article

CaV1.2 rather than CaV1.3 is coupled to glucose-stimulated insulin secretion in INS-1 832/13 cells

Nitert, Marloes Dekker, Nagorny, Cecilia L. F., Wendt, Anna, Eliasson, Lena and Mulder, Hindrik (2008). CaV1.2 rather than CaV1.3 is coupled to glucose-stimulated insulin secretion in INS-1 832/13 cells. Journal of Molecular Endocrinology, 41 (1-2), 1-11. doi: 10.1677/JME-07-0133

CaV1.2 rather than CaV1.3 is coupled to glucose-stimulated insulin secretion in INS-1 832/13 cells

2007

Journal Article

Rat insulin promoter 2-Cre recombinase mice bred onto a pure C57I3L/6J background exhibit unaltered glucose tolerance (vol 194, pg 551, 2007)

Fex, M., Wierup, N., Nitert, M. D., Ristow, M. and Mulder, H. (2007). Rat insulin promoter 2-Cre recombinase mice bred onto a pure C57I3L/6J background exhibit unaltered glucose tolerance (vol 194, pg 551, 2007). Journal of Endocrinology, 195 (3), 537-537. doi: 10.1677/JOE-07-0161e

Rat insulin promoter 2-Cre recombinase mice bred onto a pure C57I3L/6J background exhibit unaltered glucose tolerance (vol 194, pg 551, 2007)

2007

Journal Article

Rat insulin promoter 2-Cre recombinase mice bred onto a pure C57BL/6J background exhibit unaltered glucose tolerance

Fex, Malin, Wierup, Nils, Nitert, Marloes Dekker, Ristow, Michael and Mulder, Hindrik (2007). Rat insulin promoter 2-Cre recombinase mice bred onto a pure C57BL/6J background exhibit unaltered glucose tolerance. Journal of Endocrinology, 194 (3), 551-555. doi: 10.1677/JOE-07-0161

Rat insulin promoter 2-Cre recombinase mice bred onto a pure C57BL/6J background exhibit unaltered glucose tolerance

2007

Conference Publication

CaV 1.2 channels, rather than CaV 1.3 and CaV 2.3 channels, permit insulin secretion from INS-I 832/13

Nitert, M. D., Wendt, A., Eliasson, L. and Mulder, H. (2007). CaV 1.2 channels, rather than CaV 1.3 and CaV 2.3 channels, permit insulin secretion from INS-I 832/13. 43rd annual meeting of the European Association for the Study of Diabetes, Amsterdam, Netherlands, 18-21 September 2007. Springer.

CaV 1.2 channels, rather than CaV 1.3 and CaV 2.3 channels, permit insulin secretion from INS-I 832/13

2007

Journal Article

Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from C57BL/6J mice fed a high-fat diet

Fex, M., Nitert, M. Dekker, Wierup, N., Sundler, F., Ling, C. and Mulder, H. (2007). Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from C57BL/6J mice fed a high-fat diet. Diabetologia, 50 (1), 74-83. doi: 10.1007/s00125-006-0464-4

Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from C57BL/6J mice fed a high-fat diet

2006

Journal Article

Characterisation of receptors for IGF-I and insulin; evidence for hybrid insulin/IGF-I receptor in human coronary artery endothelial cells

Chisalita, Simona I., Nitert, Marloes Dekker and Arnqvist, Hans J. (2006). Characterisation of receptors for IGF-I and insulin; evidence for hybrid insulin/IGF-I receptor in human coronary artery endothelial cells. Growth Hormone & Igf Research, 16 (4), 258-266. doi: 10.1016/j.ghir.2006.06.003

Characterisation of receptors for IGF-I and insulin; evidence for hybrid insulin/IGF-I receptor in human coronary artery endothelial cells

2005

Journal Article

IGF-I/insulin hybrid receptors in human endothelial cells

Nitert, Marloes Dekker, Chisalita, Simona I., Olsson, Karolina, Bornfeldt, Karin E. and Arnqvist, Hans J. (2005). IGF-I/insulin hybrid receptors in human endothelial cells. Molecular and Cellular Endocrinology, 229 (1-2), 31-37. doi: 10.1016/j.mce.2004.10.003

IGF-I/insulin hybrid receptors in human endothelial cells