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2014 Journal Article Mycobacterium bovis BCG infection severely delays Trichuris muris expulsion and co-infection suppresses immune responsiveness to both pathogensNel, Hendrik J., du Plessis, Nelita, Kleynhans, Leanie, Loxton, Andre G., van Helden, Paul D. and Walzl, Gerhard (2014). Mycobacterium bovis BCG infection severely delays Trichuris muris expulsion and co-infection suppresses immune responsiveness to both pathogens. BMC Microbiology, 14 (1) 9, 1-13. doi: 10.1186/1471-2180-14-9 |
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2013 Journal Article Regulation of Foxp3(+) Inducible Regulatory T Cell Stability by SOCS2Knosp, Camille A., Schiering, Chris, Spence, Shaun, Carroll, Helen P., Nel, Hendrick J., Osbourn, Megan, Jackson, Ruaidhri, Lyubomska, Oksana, Malissen, Bernard, Ingram, Rebecca, Fitzgerald, Denise C., Powrie, Fiona, Fallon, Padraic G., Johnston, James A. and Kissenpfennig, Adrien (2013). Regulation of Foxp3(+) Inducible Regulatory T Cell Stability by SOCS2. Journal of Immunology, 190 (7), 3235-3245. doi: 10.4049/jimmunol.1201396 |
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2013 Journal Article Participation of MyD88 and interleukin-33 as innate drivers of Th2 immunity to Trichinella spiralisScalfone, Lisa K., Nel, Hendrik J., Gagliardo, Lucille F., Cameron, Jody L., Al-Shokri, Shaikha, Leifer, Cynthia A., Fallon, Padraic G. and Appleton, Judith A. (2013). Participation of MyD88 and interleukin-33 as innate drivers of Th2 immunity to Trichinella spiralis. Infection and Immunity, 81 (4), 1354-1363. doi: 10.1128/IAI.01307-12 |
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2013 Journal Article A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritisScally, Stephen W., Petersen, Jan, Law, Soi Cheng, Dudek, Nadine L., Nel, Hendrik J., Loh, Khai Lee, Wijeyewickrema, Lakshmi C., Eckle, Sidonia B.G., van Heemst, Jurgen, Pike, Robert N., McCluskey, James, Toes, Rene E., La Gruta, Nicole L., Purcell, Anthony W., Reid, Hugh H., Thomas, Ranjeny and Rossjohn, Jamie (2013). A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis. Journal of Experimental Medicine, 210 (12), 2569-2582. doi: 10.1084/jem.20131241 |
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2012 Journal Article T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope allelesLaw, Soi Cheng, Street, Shayna, Yu, Chien-Hsiung Alan, Capini, Christelle, Ramnoruth, Sakoontalla, Nel, Hendrik J., van Gorp, Eline, Hyde, Claire, Lau, Kim, Pahau, Helen, Purcell, Anthony W. and Thomas, Ranjeny (2012). T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles. Arthritis Research and Therapy, 14 (3) R118, R118.1-R118.12. doi: 10.1186/ar3848 |
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2012 Journal Article Enhancement of chemokine function as an immunomodulatory strategy employed by human herpesvirusesViejo-Borbolla, Abel, Martinez-Martin, Nadia, Nel, Hendrik J., Rueda, Patricia, Martin, Rocio, Blanco, Soledad, Arenzana-Seisdedos, Fernando, Thelen, Marcus, Fallon, Padraic G. and Alcami, Antonio (2012). Enhancement of chemokine function as an immunomodulatory strategy employed by human herpesviruses. PloS Pathogens, 8 (2) e1002497, e1002497. doi: 10.1371/journal.ppat.1002497 |
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2011 Journal Article SOCS2 regulates T helper type 2 differentiation and the generation of type 2 allergic responsesKnosp, Camille A., Carroll, Helen P., Elliott, Joanne, Saunders, Sean P., Nel, Hendrik J., Amu, Sylvie, Pratt, Joanne C., Spence, Shaun, Doran, Emma, Cooke, Nicola, Jackson, Ruaidhri, Swift, Jonathan, Fitzgerald, Denise C., Heaney, Liam G., Fallon, Padraic G., Kissenpfennig, Adrien and Johnston, James A. (2011). SOCS2 regulates T helper type 2 differentiation and the generation of type 2 allergic responses. Journal of Experimental Medicine, 208 (7), 1523-1531. doi: 10.1084/jem.20101167 |
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2011 Journal Article A role for TLR4 in clostridium difficile infection and the recognition of surface layer proteinsRyan, Anthony, Lynch, Mark, Smith, Sinead M., Amu, Sylvie, Nel, Hendrik J., McCoy, Claire E., Dowling, Jennifer K., Draper, Eve, O'Reilly, Vincent, McCarthy, Ciara, O'Brien, Julie, Eidhin, Deirdre Ni, O'Connell, Mary J., Keogh, Brian, Morton, Charles O., Rogers, Thomas R., Fallon, Padraic G., O'Neill, Luke A., Kelleher, Dermot and Loscher, Christine E. (2011). A role for TLR4 in clostridium difficile infection and the recognition of surface layer proteins. PloS Pathogens, 7 (6) e1002076, e1002076. doi: 10.1371/journal.ppat.1002076 |
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2011 Journal Article Impaired basophil induction leads to an age-dependent innate defect in type 2 immunity during helminth infection in miceNel, Hendrik J., Hams, Emily, Saunders, Sean P., Mangan, Niamh E., Smith, Philip, Atzberger, Ann, Flavell, Richard A., Akira, Shizuo, McKenzie, Andrew N. and Fallon, Padraic G. (2011). Impaired basophil induction leads to an age-dependent innate defect in type 2 immunity during helminth infection in mice. Journal of Immunology, 186 (8), 4631-4639. doi: 10.4049/jimmunol.1002995 |
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2011 Journal Article Identification of the Synthetic Cannabinoid R(+) WIN55,212-2 as a Novel Regulator of IFN Regulatory Factor 3 Activation and IFN-beta Expression RELEVANCE TO THERAPEUTIC EFFECTS IN MODELS OF MULTIPLE SCLEROSISDowner, Eric J., Clifford, Eileen, Gran, Bruno, Nel, Hendrik J., Fallon, Padraic G. and Moynagh, Paul N. (2011). Identification of the Synthetic Cannabinoid R(+) WIN55,212-2 as a Novel Regulator of IFN Regulatory Factor 3 Activation and IFN-beta Expression RELEVANCE TO THERAPEUTIC EFFECTS IN MODELS OF MULTIPLE SCLEROSIS. Journal of Biological Chemistry, 286 (12), 10316-10328. doi: 10.1074/jbc.M110.188599 |
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2009 Journal Article Helminth-derived immunomodulatory moleculesAdisakwattana, Poom, Saunders, Sean P., Nel, Hendrik J. and Fallon, Padraic G. (2009). Helminth-derived immunomodulatory molecules. Advances in Experimental Medicine and Biology, 666, 95-107. doi: 10.1007/978-1-4419-1601-3_8 |
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2009 Journal Article Protamine sulfate down-regulates thrombin generation by inhibiting factor V activationNi Ainle, Fionnuala, Preston, Roger J. S., Jenkins, P. Vincent, Nel, Hendrik J., Johnson, Jennifer A., Smith, Owen P., White, Barry, Fallon, Padraic G. and O'Donnell, James S. (2009). Protamine sulfate down-regulates thrombin generation by inhibiting factor V activation. Blood, 114 (8), 1658-1665. doi: 10.1182/blood-2009-05-222109 |
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2004 Journal Article Is the hygiene effect bad news for the control of infectious diseases?Walzl, Gerhard , Hussell, Tracy and Nel, Hendrik J. (2004). Is the hygiene effect bad news for the control of infectious diseases?. Current Allergy and Clinical Immunology, 17 (4), 180-186. |
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2003 Journal Article Association between tuberculosis and a polymorphic NFκB binding site in the interferon γ geneRossouw, Manda, Nel, Hendrik J., Cooke, Graham S., van Helden, Paul D. and Hoal, Eileen G. (2003). Association between tuberculosis and a polymorphic NFκB binding site in the interferon γ gene. The Lancet, 361 (9372), 1871-1872. doi: 10.1016/s0140-6736(03)13491-5 |
