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2018

Journal Article

Unintended consequences: fluid resuscitation worsens shock in an ovine model of endotoxemia

Byrne, Liam, Obonyo, Nchafatso G., Diab, Sara D., Dunster, Kimble R., Passmore, Margaret R., Boon, Ai-Ching, See Hoe, Louise, Pedersen, Sanne, Hashairi Fauzi, Mohd, Pretti Pimenta, Leticia, Van Haren, Frank, Anstey, Christopher M., Cullen, Louise, Tung, John-Paul, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2018). Unintended consequences: fluid resuscitation worsens shock in an ovine model of endotoxemia. American Journal of Respiratory and Critical Care Medicine, 198 (8), 1043-1054. doi: 10.1164/rccm.201801-0064OC

Unintended consequences: fluid resuscitation worsens shock in an ovine model of endotoxemia

2018

Conference Publication

Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxemic shock

Obonyo, N., Byrne, L., Shiino, K., Diab, S., Dunster, K., Passmore, M., Boon, A.C., See Hoe, L., Pedersen, S., Fauzi, M., Pimenta, L., Van Haren, F., Shekar, K., Anstey, C., Tung, J.P., Cullen, L., Platts, D., Chan, J., Maitland, K. and Fraser, J. (2018). Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxemic shock. 9th Congress of the World Federation of Pediatric Intensive & Critical Care Societies (WFPICCS 2018), Singapore, 9-13 June 2018. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0000538016.15507.8c

Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxemic shock

2018

Conference Publication

G265(P) Gastroenteritis aggressive versus slow treatment for rehydration (gastro study): a descriptive analysis

Houston, K., Gibb, J., Mpoya, A., Obonyo, N., Olupot-Olupot, P., George, E., Gibb, D. and Maitland, K. (2018). G265(P) Gastroenteritis aggressive versus slow treatment for rehydration (gastro study): a descriptive analysis. Annual Conference of Royal College of Paediatrics and Child Health, Glasgow, United Kingdom, 13-15 March 2018. London, United Kingdom: BMJ Publishing Group. doi: 10.1136/archdischild-2018-rcpch.258

G265(P) Gastroenteritis aggressive versus slow treatment for rehydration (gastro study): a descriptive analysis

2018

Journal Article

An ovine model of hyperdynamic endotoxemia and vital organ metabolism

Byrne, Liam, Obonyo, Nchafatso G., Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai Ching, Hoe, Louise See, Hay, Karen, Van Haren, Frank, Tung, John-Paul, Cullen, Louise, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2018). An ovine model of hyperdynamic endotoxemia and vital organ metabolism. Shock, 49 (1), 99-107. doi: 10.1097/SHK.0000000000000904

An ovine model of hyperdynamic endotoxemia and vital organ metabolism

2018

Conference Publication

Pre-transplant microcirculatory profile in an ovine model of brain stem death

Tsui, Michelle, Obonyo, Nchafatso G., Boon, Ai Ching, Hoe, Louise See, Bartnikowski, Nicole J., Passmore, Margaret R., Pedersen, Sanne Engkilde S. P., Diab, Sara D., McGiffin, David C. and Fraser, John F. (2018). Pre-transplant microcirculatory profile in an ovine model of brain stem death. Owen Wangensteen Scientific Forum / Annual Clinical Congress of the American-College-of-Surgeons (ACS), Boston, MA, United States, 21-25 October 2018. New York, United States: Elsevier. doi: 10.1016/j.jamcollsurg.2018.08.608

Pre-transplant microcirculatory profile in an ovine model of brain stem death

2018

Conference Publication

Inflammatory cytokine profiles in 24-hour brain stem death model

Boon, A. C., Hoe, L. E. See, Pederson, S. E., Obonyo, N. G., Wells, M. A., Bartnikowski, N. J., Passmore, M. R., Marshall, L., James, L., Tung, J., Suen, J. Y., Macdonald, P. S., McGiffin, D. C. and Fraser, J. F. (2018). Inflammatory cytokine profiles in 24-hour brain stem death model. 38th Annual Meeting and Scientific Sessions of the International-Society-for-Heart-and-Lung-Transplantation (ISHLT), Nice, France, 11-14 April 2018. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.healun.2018.01.506

Inflammatory cytokine profiles in 24-hour brain stem death model

2018

Book Chapter

Optimizing the patient and timing of the introduction of mechanical circulatory and extracorporeal respiratory support

Shekar, Kiran, Obonyo, Nchafatso and Fraser, John F. (2018). Optimizing the patient and timing of the introduction of mechanical circulatory and extracorporeal respiratory support. Mechanical circulatory and respiratory support. (pp. 441-468) edited by Shaun D. Gregory, Michael C. Stevens and John F. Fraser. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-810491-0.00014-X

Optimizing the patient and timing of the introduction of mechanical circulatory and extracorporeal respiratory support

2018

Conference Publication

Development of an ovine model of heart transplantation following 24-hour brain stem death

See Hoe, L., Engkilde-Pedersen, S., Obonyo, N., Wells, M., Boon, C., Bartnikowski, N., Passmore, M., McDonald, C., Black, D., Molenaar, P., Diab, S., Suen, J., Marasco, S., McGiffin, D. and Fraser, J. (2018). Development of an ovine model of heart transplantation following 24-hour brain stem death. 66th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 12th Annual Australia and New Zealand Endovascular Therapies Meeting, Brisbane, Australia, 2-5 August 2018. Chatswood, NSW, Australia: Elsevier . doi: 10.1016/j.hlc.2018.06.111

Development of an ovine model of heart transplantation following 24-hour brain stem death

2018

Conference Publication

Development of an ovine model of dilated cardiomyopathy to facilitate clinically translational research

Bartnikowski, N., Obonyo, N., Pedersen, S., Wells, M., Millar, J., Raffel, O., Suen, J., Gregory, S., Haqqani, H. and Fraser, J. (2018). Development of an ovine model of dilated cardiomyopathy to facilitate clinically translational research. 66th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 12th Annual Australia and New Zealand Endovascular Therapies Meeting, Brisbane, QLD Australia, 2 - 5 August 2018. Chatswood, NSW Australia: Elsevier . doi: 10.1016/j.hlc.2018.06.110

Development of an ovine model of dilated cardiomyopathy to facilitate clinically translational research

2018

Conference Publication

Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxaemic shock

See Hoe, L., Obonyo, N., Byrne, L., Shiino, K., Diab, S., Dunster, K., Passmore, M., Boon, C., Engkilde-Pedersen, S., Esguerra, A., Fauzi, M., Pretti Pimenta, L., Simonova, G., Van Haren, F., Shekar, K., Anstey, C., Tung, J., Cullen, L., Platts, D., Chan, J., Maitland, K. and Fraser, J. (2018). Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxaemic shock. 66th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 12th Annual Australia and New Zealand Endovascular Therapies Meeting, Brisbane, Australia, 2-5 August 2018. Chatswood, NSW, Australia: Elsevier. doi: 10.1016/j.hlc.2018.06.129

Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxaemic shock

2018

Conference Publication

Packed red cell age associated with adverse cardiovascular changes in an ovine model of septic shock resuscitation

Fanning, Jonathon P., Obonyo, Nchafatso G., Tung, John-Paul, Byrne, Liam, Simonova, Gabriela, Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai-Ching, Hoe, See Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Fauzi, Hashairi Mohd, Pretti, Pimenta Leticia, Millar, Jonathan, Anstey, Christopher, van Haren, Frank, Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John (2018). Packed red cell age associated with adverse cardiovascular changes in an ovine model of septic shock resuscitation. -, -, 2018. Philadelphia, PA United States: Lippincott Williams & Wilkins.

Packed red cell age associated with adverse cardiovascular changes in an ovine model of septic shock resuscitation

2018

Conference Publication

Neuron specific enolase and matrix metaloproteinase 9 signal silent brain infarction associated with TAVI

Fanning, Jonathon P., Hoe, See Louise E., Passmore, Margaret R., Barnett, Adrian G., Obonyo, Nchafatso G., Millar, Jonathan E., Suen, Jacky Y. and Fraser, John F. (2018). Neuron specific enolase and matrix metaloproteinase 9 signal silent brain infarction associated with TAVI. Philadelphia, PA, United States: Lippincott Williams & Wilkins.

Neuron specific enolase and matrix metaloproteinase 9 signal silent brain infarction associated with TAVI

2017

Journal Article

Acquired von willebrand syndrome in respiratory extracorporeal life support: A systematic review of the literature

Malfertheiner, M. V., Pimenta, L. P., Von Bahr, V., Millar, J. E., Obonyo, N. G., Suen, J. Y., Pellegrino, V. and Fraser, J. F. (2017). Acquired von willebrand syndrome in respiratory extracorporeal life support: A systematic review of the literature. Critical Care and Resuscitation, 19, 45-52.

Acquired von willebrand syndrome in respiratory extracorporeal life support: A systematic review of the literature

2017

Journal Article

Gastroenteritis Aggressive Versus Slow Treatment For Rehydration (GASTRO). A pilot rehydration study for severe dehydration: WHO plan C versus slower rehydration

Houston, Kirsty A., Gibb, Jack G., Mpoya, Ayub, Obonyo, Nchafatso, Olupot-Olupot, Peter, Nakuya, Margeret, Evans, Jennifer A., George, Elizabeth C., Gibb, Diana M. and Maitland, Kathryn (2017). Gastroenteritis Aggressive Versus Slow Treatment For Rehydration (GASTRO). A pilot rehydration study for severe dehydration: WHO plan C versus slower rehydration. Wellcome Open Research, 2 62, 62. doi: 10.12688/wellcomeopenres.12261.1

Gastroenteritis Aggressive Versus Slow Treatment For Rehydration (GASTRO). A pilot rehydration study for severe dehydration: WHO plan C versus slower rehydration

2017

Journal Article

Left Ventricular Global Strain Analysis by Two-Dimensional Speckle-Tracking Echocardiography: The Learning Curve

Chan, Jonathan, Shiino, Kenji, Obonyo, Nchafatso G., Hanna, Joseph, Chamberlain, Robert, Small, Andrew, Scalia, Isabel G., Scalia, William, Yamada, Akira, Hamilton-Craig, Christian R., Scalia, Gregory M. and Zamorano, Jose Luis (2017). Left Ventricular Global Strain Analysis by Two-Dimensional Speckle-Tracking Echocardiography: The Learning Curve. Journal of the American Society of Echocardiography, 30 (11), 1081-1090. doi: 10.1016/j.echo.2017.06.010

Left Ventricular Global Strain Analysis by Two-Dimensional Speckle-Tracking Echocardiography: The Learning Curve

2017

Journal Article

Myocardial and haemodynamic responses to two fluid regimens in African children with severe malnutrition and hypovolaemic shock (AFRIM study)

Obonyo, Nchafatso, Brent, Bernadette, Olupot-Olupot, Peter, van Hensbroek, Michael Boele, Kuipers, Irene, Wong, Sidney, Shiino, Kenji, Chan, Jonathan, Fraser, John, van Woensel, Job B. M. and Maitland, Kathryn (2017). Myocardial and haemodynamic responses to two fluid regimens in African children with severe malnutrition and hypovolaemic shock (AFRIM study). Critical Care, 21. doi: 10.1186/s13054-017-1679-0

Myocardial and haemodynamic responses to two fluid regimens in African children with severe malnutrition and hypovolaemic shock (AFRIM study)

2017

Conference Publication

Point-of-care testing in an ovine model of transfusion-related acute lung injury (TRALI)

Tung, John-Paul, Simonova, Gabriela, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Sultana, Annette, Hewlett, Elise, Obonyo, Nchafatso, Millar, Jonathan, Flower, Robert and Fraser, John (2017). Point-of-care testing in an ovine model of transfusion-related acute lung injury (TRALI). Pathology Update 2017, Sydney, NSW Australia, 24-26 February 2017. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.pathol.2016.12.309

Point-of-care testing in an ovine model of transfusion-related acute lung injury (TRALI)

2017

Conference Publication

Heart failure pre-clinical model development: echocardiography and cardiac strain evaluation

Obonyo, N., Bartnikowski, N., Haqqani, H., Pedersen, S., Millar, J., He, C., Shiino, K., Chan, J., Platts, D., Raffel, O., Gregory, S. and Fraser, J. (2017). Heart failure pre-clinical model development: echocardiography and cardiac strain evaluation. 65th Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting, Perth, WA Australia, 10-13 August 2017. Chatswood, NSW Australia: Elsevier Australia. doi: 10.1016/j.hlc.2017.06.212

Heart failure pre-clinical model development: echocardiography and cardiac strain evaluation

2016

Journal Article

Effects of volume resuscitation on the microcirculation in animal models of lipopolysaccharide sepsis: a systematic review

Obonyo, Nchafatso G., Fanning, Jonathon P., Ng, Angela S. Y., Pimenta, Leticia P., Shekar, Kiran, Platts, David G., Maitland, Kathryn and Fraser, John F. (2016). Effects of volume resuscitation on the microcirculation in animal models of lipopolysaccharide sepsis: a systematic review. Intensive Care Medicine Experimental, 4 (1) 38, 1-16. doi: 10.1186/s40635-016-0112-3

Effects of volume resuscitation on the microcirculation in animal models of lipopolysaccharide sepsis: a systematic review

2016

Journal Article

Career preferences of final year medical students at a medical school in Kenya-a cross sectional study

Dossajee, Hussein, Obonyo, Nchafatso and Ahmed, Syed Masud (2016). Career preferences of final year medical students at a medical school in Kenya-a cross sectional study. BMC Medical Education, 16 (1) 5. doi: 10.1186/s12909-016-0528-1

Career preferences of final year medical students at a medical school in Kenya-a cross sectional study