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2024 Journal Article Pyroptotic cell corpses are crowned with F-actin-rich filopodia that engage CLEC9A signaling in incoming dendritic cellsHolley, Caroline L., Monteleone, Mercedes, Fisch, Daniel, Libert, Alexandre E. S., Ju, Robert J., Choi, Joon H., Condon, Nicholas D., Emming, Stefan, Crawford, Joanna, Lawrence, Grace M. E. P., Coombs, Jared R., Lefevre, James G., Bajracharya, Rinie, Lahoud, Mireille H., Yap, Alpha S., Hamilton, Nicholas, Stehbens, Samantha J., Kagan, Jonathan C., Ariotti, Nicholas, Burgener, Sabrina S. and Schroder, Kate (2024). Pyroptotic cell corpses are crowned with F-actin-rich filopodia that engage CLEC9A signaling in incoming dendritic cells. Nature Immunology, 26 (1) eaas8995, 1-35. doi: 10.1038/s41590-024-02024-3 |
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2024 Journal Article Adaptive microtubule reinforcement enables cell migration through 3D environmentsJu, Robert J. and Stehbens, Samantha J. (2024). Adaptive microtubule reinforcement enables cell migration through 3D environments. Nature Cell Biology. doi: 10.1038/s41556-024-01477-w |
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2024 Journal Article Compression-dependent microtubule reinforcement enables cells to navigate confined environmentsJu, Robert J., Falconer, Alistair D., Schmidt, Christanny J., Martinez, Marco A. Enriquez, Dean, Kevin M., Fiolka, Reto P., Sester, David P., Nobis, Max, Timpson, Paul, Lomakin, Alexis J., Danuser, Gaudenz, White, Melanie D., Haass, Nikolas K., Oelz, Dietmar B. and Stehbens, Samantha J. (2024). Compression-dependent microtubule reinforcement enables cells to navigate confined environments. Nature Cell Biology, 26 (9), 1520-1534. doi: 10.1038/s41556-024-01476-x |
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2023 Journal Article Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 functionJami, Sina, Deuis, Jennifer R., Klasfauseweh, Tabea, Cheng, Xiaoyang, Kurdyukov, Sergey, Chung, Felicity, Okorokov, Andrei L., Li, Shengnan, Zhang, Jiangtao, Cristofori-Armstrong, Ben, Israel, Mathilde R., Ju, Robert J., Robinson, Samuel D., Zhao, Peng, Ragnarsson, Lotten, Andersson, Åsa, Tran, Poanna, Schendel, Vanessa, McMahon, Kirsten L., Tran, Hue N. T., Chin, Yanni K.-Y., Zhu, Yifei, Liu, Junyu, Crawford, Theo, Purushothamvasan, Saipriyaa, Habib, Abdella M., Andersson, David A., Rash, Lachlan D., Wood, John N. ... Vetter, Irina (2023). Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function. Nature Communications, 14 (1) 2442. doi: 10.1038/s41467-023-37963-2 |
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2022 Journal Article Persister state-directed transitioning and vulnerability in melanomaChauvistré, Heike, Shannan, Batool, Daignault-Mill, Sheena M., Ju, Robert J., Picard, Daniel, Egetemaier, Stefanie, Váraljai, Renáta, Gibhardt, Christine S., Sechi, Antonio, Kaschani, Farnusch, Keminer, Oliver, Stehbens, Samantha J., Liu, Qin, Yin, Xiangfan, Jeyakumar, Kirujan, Vogel, Felix C. E., Krepler, Clemens, Rebecca, Vito W., Kubat, Linda, Lueong, Smiths S., Forster, Jan, Horn, Susanne, Remke, Marc, Ehrmann, Michael, Paschen, Annette, Becker, Jürgen C., Helfrich, Iris, Rauh, Daniel, Kaiser, Markus ... Roesch, Alexander (2022). Persister state-directed transitioning and vulnerability in melanoma. Nature Communications, 13 (1) 3055, 3055. doi: 10.1038/s41467-022-30641-9 |
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2022 Journal Article Patient-derived xenograft models capture genomic heterogeneity in endometrial cancerBonazzi, Vanessa F., Kondrashova, Olga, Smith, Deborah, Nones, Katia, Sengal, Asmerom T., Ju, Robert, Packer, Leisl M., Koufariotis, Lambros T., Kazakoff, Stephen H., Davidson, Aimee L., Ramarao-Milne, Priya, Lakis, Vanessa, Newell, Felicity, Rogers, Rebecca, Davies, Claire, Nicklin, James, Garrett, Andrea, Chetty, Naven, Perrin, Lewis, Pearson, John V., Patch, Ann-Marie, Waddell, Nicola and Pollock, Pamela M. (2022). Patient-derived xenograft models capture genomic heterogeneity in endometrial cancer. Genome Medicine, 14 (1) 3, 1-19. doi: 10.1186/s13073-021-00990-z |
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2021 Journal Article Collagen polarization promotes epithelial elongation by stimulating locoregional cell proliferationKatsuno-Kambe, Hiroko, Teo, Jessica L., Ju, Robert J., Hudson, James, Stehbens, Samantha J. and Yap, Alpha S. (2021). Collagen polarization promotes epithelial elongation by stimulating locoregional cell proliferation. eLife, 10 e67915. doi: 10.7554/elife.67915 |
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2021 Journal Article Abstract PR007: Genomic characterization of endometrial cancer patient-derived xenografts reveals intratumor heterogeneityKondrashova, Olga, Bonazzi, Vanessa F., Smith, Deborah, Nones, Katia, Sengal, Asmerom, Ju, Robert, Packer, Leisl M., Koufariotis, Lambros T, Kazakoff, Stephen H., Davidson, Aimee L., Ramarao-Milne, Priya, Lakis, Vanessa, Newell, Felicity, Rogers, Rebecca, Davies, Claire, Chetty, Naven, Perrin, Lewis, Pearson, John, Patch, Ann-Marie, Garrett, Andrea, Waddell, Nicola, Pollock, Pamela and Nicklin, James (2021). Abstract PR007: Genomic characterization of endometrial cancer patient-derived xenografts reveals intratumor heterogeneity. Clinical Cancer Research, 27 (3_Supplement). doi: 10.1158/1557-3265.endomet20-pr007 |
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2020 Journal Article A versatile oblique plane microscope for large-scale and high-resolution imaging of subcellular dynamicsSapoznik, Etai, Chang, Bo-Jui, Huh, Jaewon, Ju, Robert J., Azarova, Evgenia, Pohlkamp, Theresa, Welf, Erik S., Broadbent, David, Carisey, Alexandre F., Stehbens, Samantha J., Lee, Kyung-Min, Marin, Arnaldo, Hanker, Ariella B., Schmidt, Jens C., Arteaga, Carlos L., Bin Yang, , Kobayashi, Yoshihiko, Tata, Purushothama Rao, Kruithoff, Rory, Doubrovinski, Konstantin, Shepherd, Douglas P., Millett-Sikking, Alfred, York, Andrew G., Dean, Kevin M. and Fiolka, Reto P. (2020). A versatile oblique plane microscope for large-scale and high-resolution imaging of subcellular dynamics. eLife, 9 e57681, 1-39. doi: 10.7554/elife.57681 |
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2020 Journal Article Caveolae control contractile tension for epithelia to eliminate tumor cellsTeo, Jessica L., Gomez, Guillermo A., Weeratunga, Saroja, Davies, Elizabeth M., Noordstra, Ivar, Budnar, Srikanth, Katsuno-Kambe, Hiroko, McGrath, Meagan J., Verma, Suzie, Tomatis, Vanesa, Acharya, Bipul R., Balasubramaniam, Lakshmi, Templin, Rachel M., McMahon, Kerrie-Ann, Lee, Yoke Seng, Ju, Robert J., Stebhens, Samantha J., Ladoux, Benoit, Mitchell, Christina A., Collins, Brett M., Parton, Robert G. and Yap, Alpha S. (2020). Caveolae control contractile tension for epithelia to eliminate tumor cells. Developmental Cell, 54 (1), 75-91.e7. doi: 10.1016/j.devcel.2020.05.002 |
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2018 Journal Article Bcl-2 inhibitors enhance FGFR inhibitor-induced mitochondrial-dependent cell death in FGFR2-mutant endometrial cancerPacker, Leisl M., Stehbens, Samantha J., Bonazzi, Vanessa F., Gunter, Jennifer H., Ju, Robert J., Ward, Micheal, Gartside, Michael G., Byron, Sara A. and Pollock, Pamela M. (2018). Bcl-2 inhibitors enhance FGFR inhibitor-induced mitochondrial-dependent cell death in FGFR2-mutant endometrial cancer. Molecular Oncology, 13 (4), 738-756. doi: 10.1002/1878-0261.12422 |
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2018 Journal Article The role of melanoma cell-stroma interaction in cell motility, invasion, and metastasisJu, Robert J., Stehbens, Samantha J. and Haass, Nikolas K. (2018). The role of melanoma cell-stroma interaction in cell motility, invasion, and metastasis. Frontiers in Medicine, 5 (NOV) 307, 1-9. doi: 10.3389/fmed.2018.00307 |
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2018 Journal Article FGFR2b activating mutations disrupt cell polarity to potentiate migration and invasion in endometrial cancerStehbens, Samantha J., Ju, Robert J., Adams, Mark N., Perry, Samuel, Haass, Nikolas K., Bryant, David M. and Pollock, Pamela M. (2018). FGFR2b activating mutations disrupt cell polarity to potentiate migration and invasion in endometrial cancer. Journal of Cell Science, 131 (15) jcs.213678, 1-16. doi: 10.1242/jcs.213678 |
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2017 Journal Article PI3K inhibitors synergize with FGFR inhibitors to enhance antitumor responses in FGFR2mutant endometrial cancersPacker, Leisl M., Geng, Xinyan, Bonazzi, Vanessa F., Ju, Robert J., Mahon, Clare E., Cummings, Margaret C., Stephenson, Sally-Anne and Pollock, Pamela M. (2017). PI3K inhibitors synergize with FGFR inhibitors to enhance antitumor responses in FGFR2mutant endometrial cancers. Molecular Cancer Therapeutics, 16 (4), 637-648. doi: 10.1158/1535-7163.MCT-16-0415 |
