|
2024 Journal Article Insights into the structure of NLR family member X1: Paving the way for innovative drug discoveryJewell, Shannon, Nguyen, Thanh Binh, Ascher, David B. and Robertson, Avril A.B. (2024). Insights into the structure of NLR family member X1: Paving the way for innovative drug discovery. Computational and Structural Biotechnology Journal, 23, 3506-3513. doi: 10.1016/j.csbj.2024.09.013 |
|
2024 Journal Article AlzDiscovery: A computational tool to identify Alzheimer's disease‐causing missense mutations using protein structure informationPan, Qisheng, Parra, Georgina Becerra, Myung, Yoochan, Portelli, Stephanie, Nguyen, Thanh Binh and Ascher, David B. (2024). AlzDiscovery: A computational tool to identify Alzheimer's disease‐causing missense mutations using protein structure information. Protein Science, 33 (10) e5147, e5147. doi: 10.1002/pro.5147 |
|
2024 Journal Article Targeting the Plasmodium falciparum UCHL3 ubiquitin hydrolase using chemically constrained peptidesKing, Harry R., Bycroft, Mark, Nguyen, Thanh-Binh, Kelly, Geoff, Vinogradov, Alexander A., Rowling, Pamela J E, Stott, Katherine, Ascher, David B., Suga, Hiroaki, Itzhaki, Laura S. and Artavanis-Tsakonas, Katerina (2024). Targeting the Plasmodium falciparum UCHL3 ubiquitin hydrolase using chemically constrained peptides. Proceedings of the National Academy of Sciences of the United States of America, 121 (21) e2322923121. doi: 10.1073/pnas.2322923121 |
|
2024 Journal Article Mechanisms of biased agonism by Gα<sub>i/o</sub>-biased stapled peptide agonists of the relaxin-3 receptorJayakody, Tharindunee, Inoue, Asuka, Kannan, Srinivasaraghavan, Nakamura, Gaku, Kawakami, Kouki, Mendis, Krishan, Nguyen, Thanh-Binh, Li, Jianguo, Herr, Deron R., Verma, Chandra S. and Dawe, Gavin S. (2024). Mechanisms of biased agonism by Gαi/o-biased stapled peptide agonists of the relaxin-3 receptor. Science Signaling, 17 (823) eabl5880. doi: 10.1126/scisignal.abl5880 |
|
2024 Journal Article Characterization on the oncogenic effect of the missense mutations of p53 via machine learningPan, Qisheng, Portelli, Stephanie, Nguyen, Thanh Binh and Ascher, David B. (2024). Characterization on the oncogenic effect of the missense mutations of p53 via machine learning. Briefings in Bioinformatics, 25 (1) bbad428, 1-13. doi: 10.1093/bib/bbad428 |
|
2023 Journal Article LEGO-CSM: a tool for functional characterization of proteinsNguyen, Thanh Binh, de Sá, Alex G. C., Rodrigues, Carlos H. M., Pires, Douglas E. V. and Ascher, David B. (2023). LEGO-CSM: a tool for functional characterization of proteins. Bioinformatics, 39 (7) btad402, 1-4. doi: 10.1093/bioinformatics/btad402 |
|
2022 Journal Article A bias of Asparagine to Lysine mutations in SARS-CoV-2 outside the receptor binding domain affects protein flexibilityBoer, Jennifer C., Pan, Qisheng, Holien, Jessica K., Nguyen, Thanh-Binh, Ascher, David B. and Plebanski, Magdalena (2022). A bias of Asparagine to Lysine mutations in SARS-CoV-2 outside the receptor binding domain affects protein flexibility. Frontiers in Immunology, 13 954435, 1-13. doi: 10.3389/fimmu.2022.954435 |
|
2022 Journal Article kinCSM : Using graph‐based signatures to predict small molecule CDK2 inhibitorsZhou, Yunzhuo, Al‐Jarf, Raghad, Alavi, Azadeh, Nguyen, Thanh Binh, Rodrigues, Carlos H. M., Pires, Douglas E. V. and Ascher, David B. (2022). kinCSM : Using graph‐based signatures to predict small molecule CDK2 inhibitors. Protein Science, 31 (11) e4453, 1-11. doi: 10.1002/pro.4453 |
|
2022 Journal Article Systematic evaluation of computational tools to predict the effects of mutations on protein stability in the absence of experimental structuresPan, Qisheng, Nguyen, Thanh Binh, Ascher, David B and Pires, Douglas E V (2022). Systematic evaluation of computational tools to predict the effects of mutations on protein stability in the absence of experimental structures. Briefings in Bioinformatics, 23 (2) bbac025. doi: 10.1093/bib/bbac025 |
|
2021 Journal Article Structure-guided machine learning prediction of drug resistance mutations in Abelson 1 kinaseZhou, Yunzhuo, Portelli, Stephanie, Pat, Megan, Rodrigues, Carlos H.M., Nguyen, Thanh-Binh, Pires, Douglas E.V. and Ascher, David B. (2021). Structure-guided machine learning prediction of drug resistance mutations in Abelson 1 kinase. Computational and Structural Biotechnology Journal, 19, 5381-5391. doi: 10.1016/j.csbj.2021.09.016 |
