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2024

Journal Article

Trial protocol for SiroSkin: a randomised double-blind placebo-controlled trial of topical sirolimus in chemoprevention of facial squamous cell carcinomas in solid organ transplant recipients

Dousset, Lea, Chambers, Daniel C., Webster, Angela, Isbel, Nicole, Campbell, Scott, Duarte, Carla, Collins, Louisa, Damian, Diona, Tseng, Anne, Karlsen, Emma, Ilinsky, Olga Victoria, Brown, Susan, Schaider, Helmut, Soyer, H. Peter, Ospino, Daniel Ariza, Hogarth, Sam, Chong, Alvin H., Mar, Victoria, McKenzie, Scott, Gin, Douglas, Fernandez-Penas, Pablo, Kern, Johannes S., Loewe, Katja, Roy, Edwige, Herschtal, Alan and Khosrotehrani, Kiarash (2024). Trial protocol for SiroSkin: a randomised double-blind placebo-controlled trial of topical sirolimus in chemoprevention of facial squamous cell carcinomas in solid organ transplant recipients. Trials, 25 (1) 789. doi: 10.1186/s13063-024-08619-3

Trial protocol for SiroSkin: a randomised double-blind placebo-controlled trial of topical sirolimus in chemoprevention of facial squamous cell carcinomas in solid organ transplant recipients

2024

Journal Article

Cyclic tachyplesin I kills proliferative, non-proliferative and drug-resistant melanoma cells without inducing resistance

Benfield, Aurélie H., Vernen, Felicitas, Young, Reuben S.E., Nadal-Bufí, Ferran, Lamb, Henry, Hammerlindl, Heinz, Craik, David J., Schaider, Helmut, Lawrence, Nicole, Blanksby, Stephen J. and Henriques, Sónia Troeira (2024). Cyclic tachyplesin I kills proliferative, non-proliferative and drug-resistant melanoma cells without inducing resistance. Pharmacological Research, 207 107298, 107298. doi: 10.1016/j.phrs.2024.107298

Cyclic tachyplesin I kills proliferative, non-proliferative and drug-resistant melanoma cells without inducing resistance

2024

Conference Publication

Environmentally stressed drug-naïve melanoma cell subpopulations share a molecular signature with drug-induced early persister cells

Kangachar, S. Asgharzadeh, Ahmed, F., Al Emran, A., Boyle, G., Spoerri, L., Schaider, H. and Haass, N.K. (2024). Environmentally stressed drug-naïve melanoma cell subpopulations share a molecular signature with drug-induced early persister cells. Society for Investigative Dermatology (SID) 2024 Meeting, Dallas, TX United States, 15-18 May 2024. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2024.06.641

Environmentally stressed drug-naïve melanoma cell subpopulations share a molecular signature with drug-induced early persister cells

2024

Conference Publication

Environmentally stressed drug-naive melanoma cell subpopulations share a molecular signature with drug-induced early persister cells

Kangachar, S. Asgharzadeh, Ahmed, F., Al Emran, A., Boyle, G., Spoerri, L., Schaider, H. and Haass, N. K. (2024). Environmentally stressed drug-naive melanoma cell subpopulations share a molecular signature with drug-induced early persister cells. Society for Investigative Dermatology (SID) 2024 Meeting, Dallas, TX, United States, 15-18 May 2024. Oxford, United Kingdom: Elsevier.

Environmentally stressed drug-naive melanoma cell subpopulations share a molecular signature with drug-induced early persister cells

2024

Conference Publication

A calcium influx pathway regulates adaptive melanoma drug tolerance

Guan, Yimeng, Robitaille, Melanie, Torrano, Joachim, Haass, Nikolas, Roberts-Thomson, Sarah, Monteith, Gregory and Schaider, Helmut (2024). A calcium influx pathway regulates adaptive melanoma drug tolerance. ASDR 2024 Annual Scientific Meeting, Sydney, NSW Australia, 18-20 July 2024.

A calcium influx pathway regulates adaptive melanoma drug tolerance

2024

Conference Publication

Exploring calcium signalling remodelling during adaptive cancer drug tolerance

Robitaille, Melanie, Schaider, Helmut, Monteith, Gregory and Roberts-Thomson, Sarah (2024). Exploring calcium signalling remodelling during adaptive cancer drug tolerance. Calcium Signaling- Gordon Research Conference, Barga, Lucca, Italy, 30 June - 5 July 2024.

Exploring calcium signalling remodelling during adaptive cancer drug tolerance

2024

Conference Publication

O-GlcNAc transferase drives the proliferative state in adaptive drug tolerance

Menon, Dinoop Ravindran, Hammerlindl, Heinz, Gimenez, Gregory, Zuegner, Elmar, Magens, Christoph, Eccles, Michael, Fujita, Mayumi and Schaider, Helmut (2024). O-GlcNAc transferase drives the proliferative state in adaptive drug tolerance. AACR Annual Meeting 2024, San Diego, CA United States, 5-10 April 2024. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2024-lb293

O-GlcNAc transferase drives the proliferative state in adaptive drug tolerance

2023

Conference Publication

Exploring calcium signalling remodelling during adaptive cancer drug tolerance

Robitaille, Mélanie, Schaider, Helmut, Roberts-Thomson, Sarah and Monteith, Gregory (2023). Exploring calcium signalling remodelling during adaptive cancer drug tolerance. ASCEPT Annual Scientific Meeting, Sydney, NSW Australia, 20-23 November 2023.

Exploring calcium signalling remodelling during adaptive cancer drug tolerance

2023

Journal Article

H3K4me3 remodeling induced acquired resistance through O-GlcNAc transferase

Menon, Dinoop Ravindran, Hammerlindl, Heinz, Gimenez, Gregory, Hammerlindl, Sabrina, Zuegner, Elmar, Torrano, Joachim, Bordag, Natalie, Emran, Abdullah Al, Giam, Maybelline, Denil, Simon, Pavelka, Norman, Tan, Aik-Choon, Sturm, Richard A., Haass, Nikolas K., Rancati, Giulia, Herlyn, Meenhard, Magnes, Christoph, Eccles, Michael R., Fujita, Mayumi and Schaider, Helmut (2023). H3K4me3 remodeling induced acquired resistance through O-GlcNAc transferase. Drug Resistance Updates, 71 100993, 100993. doi: 10.1016/j.drup.2023.100993

H3K4me3 remodeling induced acquired resistance through O-GlcNAc transferase

2023

Conference Publication

High-plex spatial profiling of cutaneous squamous cell carcinoma to identify biomarkers associated with clinical outcomes: The cMIC study

Ladwa, R., Monkman, J., Sadeghirad, H., Cooper, C., Belz, G., Bowman, J., Schaider, H., Liu, H., Kulasinghe, A. and Porceddu, S. (2023). High-plex spatial profiling of cutaneous squamous cell carcinoma to identify biomarkers associated with clinical outcomes: The cMIC study. ESMO Congress 2023, Madrid, Spain, 20-24 October 2023. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.annonc.2023.09.2278

High-plex spatial profiling of cutaneous squamous cell carcinoma to identify biomarkers associated with clinical outcomes: The cMIC study

2023

Conference Publication

1244 Epigenetic and metabolic vulnerabilities of adaptive drug resistance to targeted therapies in melanoma

Torrano, J., Ravindran-Menon, D., Hammerlindl, H., Hammerlindl, S., Emran, A.A., Bordag, N., Zuegner, E., Haass, N.K., Sadowski, M., Stow, J., Magnes, C., Fujita, M. and Schaider, H. (2023). 1244 Epigenetic and metabolic vulnerabilities of adaptive drug resistance to targeted therapies in melanoma. 1st International Societies for Investigative Dermatology Meeting (ISID 2023), Tokyo, Japan, 10-13 May 2023. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2023.03.1258

1244 Epigenetic and metabolic vulnerabilities of adaptive drug resistance to targeted therapies in melanoma

2023

Conference Publication

Anatomical distribution of severe keratinocyte carcinomas in solid organ transplant recipients

Cox, Charlotte, Lee, Ruby, Liyanage, Upekha, Brown, Susan, Isbel, Nicole, Chambers, Daniel, Griffin, Anthony, Campbell, Scott, Hopkins, Peter, Schaider, Helmut, Soyer, Peter and Khosrotehrani, Kiarash (2023). Anatomical distribution of severe keratinocyte carcinomas in solid organ transplant recipients. HOBOKEN: WILEY.

Anatomical distribution of severe keratinocyte carcinomas in solid organ transplant recipients

2023

Conference Publication

Distinct HOX gene family DNA methylation profiles in histologically normal skin dependent on dermoscopic pattern of adjacent nevi

Muse, Meghan E., Schaider, Helmut, Oey, Harald, Soyer, H. Peter, Christensen, Brock C. and Stark, Mitchell S. (2023). Distinct HOX gene family DNA methylation profiles in histologically normal skin dependent on dermoscopic pattern of adjacent nevi. 114th Annual Meeting of the American Association for Cancer Research (AACR), Orlando Fl, Apr 14-19, 2023. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. doi: 10.1158/1538-7445.AM2023-6000

Distinct HOX gene family DNA methylation profiles in histologically normal skin dependent on dermoscopic pattern of adjacent nevi

2023

Conference Publication

MITF-mediated changes of tumour architecture, tensile stress and in extracellular matrix (ECM) control intratumour heterogeneity in melanoma

Spoerri, L., Tonnessen-Murray, C. A., Beaumont, K. A., Hill, D. S., Jurek, R. J., Gunasingh, G., Vanwalleghem, G., Daignault, S., Fane, M. E., Schaider, H., Smith, A., Stehbens, S. J., Weninger, W., Scott, E. E., Gabrielli, B. and Haass, N. (2023). MITF-mediated changes of tumour architecture, tensile stress and in extracellular matrix (ECM) control intratumour heterogeneity in melanoma. Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF), Berlin, Germany, 11-14 March 2020. Chichester, West Sussex United Kingdom: Wiley-Blackwell.

MITF-mediated changes of tumour architecture, tensile stress and in extracellular matrix (ECM) control intratumour heterogeneity in melanoma

2023

Journal Article

Distinct HOX gene family DNA methylation profiles in histologically normal skin dependent on dermoscopic pattern of adjacent nevi

Muse, Meghan E., Schaider, Helmut, Oey, Harald, Soyer, H. Peter, Christensen, Brock C. and Stark, Mitchell S. (2023). Distinct HOX gene family DNA methylation profiles in histologically normal skin dependent on dermoscopic pattern of adjacent nevi. Journal of Investigative Dermatology, 143 (9), 1830-1834. doi: 10.1016/j.jid.2023.03.1653

Distinct HOX gene family DNA methylation profiles in histologically normal skin dependent on dermoscopic pattern of adjacent nevi

2023

Journal Article

Three‐dimensional multispectral facial imaging to monitor actinic damage treated with 5‐fluorouracil

Torrano, Joachim, Hishon, Matt, Robinson, Mitchell, Raphael, Anthony, Wu, Jason, Betz‐Stablein, Brigid, Kopera, Daisy, Soyer, Hans Peter and Schaider, Helmut (2023). Three‐dimensional multispectral facial imaging to monitor actinic damage treated with 5‐fluorouracil. JEADV Clinical Practice, 2 (2), 273-281. doi: 10.1002/jvc2.122

Three‐dimensional multispectral facial imaging to monitor actinic damage treated with 5‐fluorouracil

2023

Journal Article

Nicotinamide for skin-cancer chemoprevention in transplant recipients

Allen, Nicholas C., Martin, Andrew J., Snaidr, Victoria A., Eggins, Renee, Chong, Alvin H., Fernandéz-Peñas, Pablo, Gin, Douglas, Sidhu, Shireen, Paddon, Vanessa L., Banney, Leith A., Lim, Adrian, Upjohn, Edward, Schaider, Helmut, Ganhewa, Aparna D., Nguyen, Jennifer, Mckenzie, Catriona A., Prakash, Saurabh, Mclean, Catriona, Lochhead, Alistair, Ibbetson, Jan, Dettrick, Andrew, Landgren, Anthony, Allnutt, Katherine J., Allison, Clare, Davenport, Rachael B., Mumford, Blake P., Wong, Brittany, Stagg, Brendan, Tedman, Alexander ... Damian, Diona L. (2023). Nicotinamide for skin-cancer chemoprevention in transplant recipients. New England Journal of Medicine, 388 (9), 804-812. doi: 10.1056/NEJMoa2203086

Nicotinamide for skin-cancer chemoprevention in transplant recipients

2023

Journal Article

Tribute to reviewers

Khosrotehrani, Kiarash and Schaider, Helmut (2023). Tribute to reviewers. Australasian Journal of Dermatology, 64 (1), 162-166. doi: 10.1111/ajd.13990

Tribute to reviewers

2023

Journal Article

Skin cancer excisions and histopathology outcomes when following a contemporary population‐based cohort longitudinally with 3D total‐body photography

Soyer, H. Peter, O’Hara, Montana, V. Silva, Carina, Horsham, Caitlin, Jayasinghe, Dilki, Sanjida, Saira, Schaider, Helmut, Aitken, Joanne, Sturm, Richard A., Prow, Tarl, Menzies, Scott W. and Janda, Monika (2023). Skin cancer excisions and histopathology outcomes when following a contemporary population‐based cohort longitudinally with 3D total‐body photography. Skin Health and Disease, 3 (2) e216, e216. doi: 10.1002/ski2.216

Skin cancer excisions and histopathology outcomes when following a contemporary population‐based cohort longitudinally with 3D total‐body photography

2022

Journal Article

Genome-scale DNA methylation analysis identifies repeat element alterations that modulate the genomic stability of melanocytic nevi

Muse, Meghan E., Bergman, Drew T., Salas, Lucas A., Tom, Lisa N., Tan, Jean-Marie, Laino, Antonia, Lambie, Duncan, Sturm, Richard A., Schaider, Helmut, Soyer, H. Peter, Christensen, Brock C. and Stark, Mitchell S. (2022). Genome-scale DNA methylation analysis identifies repeat element alterations that modulate the genomic stability of melanocytic nevi. The Journal of Investigative Dermatology, 142 (7), 1893-1902.e7. doi: 10.1016/j.jid.2021.11.025

Genome-scale DNA methylation analysis identifies repeat element alterations that modulate the genomic stability of melanocytic nevi