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2019 Journal Article Parkinson's disease age at onset genome-wide association study: defining heritability, genetic loci, and α-synuclein mechanismsBlauwendraat, Cornelis, Heilbron, Karl, Vallerga, Costanza L., Bandres-Ciga, Sara, von Coelln, Rainer, Pihlstrøm, Lasse, Simón-Sánchez, Javier, Schulte, Claudia, Sharma, Manu, Krohn, Lynne, Siitonen, Ari, Iwaki, Hirotaka, Leonard, Hampton, Noyce, Alastair J., Tan, Manuela, Gibbs, J. Raphael, Hernandez, Dena G., Scholz, Sonja W., Jankovic, Joseph, Shulman, Lisa M., Lesage, Suzanne, Corvol, Jean-Christophe, Brice, Alexis, van Hilten, Jacobus J., Marinus, Johan, Eerola-Rautio, Johanna, Tienari, Pentti, Majamaa, Kari, Toft, Mathias ... Singleton, Andrew B. (2019). Parkinson's disease age at onset genome-wide association study: defining heritability, genetic loci, and α-synuclein mechanisms. Movement Disorders, 34 (6) mds.27659, 866-875. doi: 10.1002/mds.27659 |
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2019 Journal Article Examining the impact of imputation errors on fine-mapping using DNA methylation QTL as a model traitChundru, V. Kartik, Marioni, Riccardo E., Prendergast, James G. D., Vallerga, Costanza L., Lin, Tian, Berveridge, Allan J., SGPD Consortium, Gratten, Jacob, Hume, David A., Deary, Ian J., Wray, Naomi R., Visscher, Peter M. and McRae, Allan F. (2019). Examining the impact of imputation errors on fine-mapping using DNA methylation QTL as a model trait. Genetics, 212 (3), 577-586. doi: 10.1534/genetics.118.301861 |
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2019 Journal Article Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson's disease heritabilityReynolds, Regina H., Botia, Juan, Nalls, Mike A., Hardy, John, Taliun, Sarah A. Gagliano, Ryten, Mina, Noyce, Alastair J., Nicolas, Aude, Cookson, Mark R., Bandres-Ciga, Sara, Gibbs, J. Raphael, Hernandez, Dena G., Singleton, Andrew B., Reed, Xylena, Leonard, Hampton, Blauwendraat, Cornelis, Faghri, Faraz, Bras, Jose, Guerreiro, Rita, Tucci, Arianna, Kia, Demis A., Houlden, Henry, Plun-Favreau, Helene, Mok, Kin Y., Wood, Nicholas W., Lovering, Ruth, R'Bibo, Lea, Rizig, Mie, Chelban, Viorica ... Pearson, John (2019). Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson's disease heritability. Npj Parkinsons Disease, 5 (1) 6, 6. doi: 10.1038/s41531-019-0076-6 |
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2019 Journal Article Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influencesKarlsson Linnér, Richard, Biroli, Pietro, Kong, Edward, Meddens, S. Fleur W., Wedow, Robbee, Fontana, Mark Alan, Lebreton, Maël, Tino, Stephen P., Abdellaoui, Abdel, Hammerschlag, Anke R., Nivard, Michel G., Okbay, Aysu, Rietveld, Cornelius A., Timshel, Pascal N., Trzaskowski, Maciej, Vlaming, Ronald de, Zünd, Christian L., Bao, Yanchun, Buzdugan, Laura, Caplin, Ann H., Chen, Chia-Yen, Eibich, Peter, Fontanillas, Pierre, Gonzalez, Juan R., Joshi, Peter K., Karhunen, Ville, Kleinman, Aaron, Levin, Remy Z., Lill, Christina M. ... Beauchamp, Jonathan P. (2019). Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences. Nature Genetics, 51 (2), 245-257. doi: 10.1038/s41588-018-0309-3 |
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2019 Conference Publication Connecting comorbidities with brain-gut-microbiome stress axis biology in autism spectrum disorderYap, Chloe, Wray, Naomi, Brix, Susanne and Gratten, Jacob (2019). Connecting comorbidities with brain-gut-microbiome stress axis biology in autism spectrum disorder. 27th World Congress of Psychiatric Genetics (WCPG), Los Angeles, California, 26-31 October 2019 . Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.euroneuro.2019.08.215 |
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2019 Conference Publication Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothersGratten, Jacob, Yang, Yuanhao, Trzaskowski, Maciej, Kemper, Kathryn, Yengo, Loic, Zheng, Zhili, Zhang, Futao, Zhu, Zhihong, Mcrae, Allan, Yang, Jian, Wray, Naomi and Visscher, Peter (2019). Common genetic variation explains a high proportion of the elevated risk of psychiatric disorders in children of younger mothers. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October, 2018. Amsterdam, Netherlands: Elsevier BV. doi: 10.1016/j.euroneuro.2018.08.167 |
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2019 Journal Article The rs2516839 variation of USF1 gene is associated with 4-year mortality of nonagenarian women: the Vitality 90+studyOzsait-Selcuk, B., Komurcu-Bayrak, E., Jylha, M., Luukkaala, T., Perola, M., Kristiansson, K., Mononen, N., Hurme, M., Kahonen, M., Goebeler, S., Laaksonen, R., Hervonen, A., Erginel-Unaltuna, N., Karhunen, P. J. and Lehtimaki, T. (2019). The rs2516839 variation of USF1 gene is associated with 4-year mortality of nonagenarian women: the Vitality 90+study. Annals of Human Genetics, 83 (1), 34-45. doi: 10.1111/ahg.12282 |
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2019 Conference Publication First genome-wide association study of schizophrenia in an Indian population reveals a novel susceptibility locusPeriyasamy, Sathish, John, Sujit, Padmavati, Raman, Rajendren, Preeti, Thirunavukkarasu, Priyadarshini, Gratten, Jacob, Holliday, Elizabeth, Bakshi, Andrew, Jorde, Lynn, Brown, Matthew, Wray, Naomi, Suetani, Rachel, Giacomotto, Jean, Thara, Rangaswamy and Mowry, Bryan (2019). First genome-wide association study of schizophrenia in an Indian population reveals a novel susceptibility locus. 26th World Congress of Psychiatric Genetics (WCPG), Glasgow, Scotland, 11-15 October 2018. Amsterdam, The Netherlands: Elsevier . doi: 10.1016/j.euroneuro.2018.08.017 |
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2018 Journal Article Imprint of assortative mating on the human genomeYengo, Loic, Robinson, Matthew R., Keller, Matthew C., Kemper, Kathryn E., Yang, Yuanhao, Trzaskowski, Maciej, Gratten, Jacob, Turley, Patrick, Cesarini, David, Benjamin, Daniel J., Wray, Naomi R., Goddard, Michael E., Yang, Jian and Visscher, Peter M. (2018). Imprint of assortative mating on the human genome. Nature Human Behaviour, 2 (12), 948-954. doi: 10.1038/s41562-018-0476-3 |
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2018 Other Outputs The genetic relationship between female reproductive traits and six psychiatric disordersNi, Guiyan, Amare, Azmeraw, Zhou, Xuan, Mills, Natalie, Gratten, Jacob and Lee, Sang Hong (2018). The genetic relationship between female reproductive traits and six psychiatric disorders. doi: 10.1101/433946 |
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2018 Journal Article Study protocol for the Australian autism biobank: an international resource to advance autism discovery researchAlvares, Gail A., Dawson, Paul A., Dissanayake, Cheryl, Eapen, Valsamma, Gratten, Jacob, Grove, Rachel, Henders, Anjali, Heussler, Helen, Lawson, Lauren, Masi, Anne, Raymond, Emma, Rose, Felicity, Wallace, Leanne, Wray, Naomi R. and Whitehouse, Andrew J. O. (2018). Study protocol for the Australian autism biobank: an international resource to advance autism discovery research. BMC Pediatrics, 18 (1) 284, 284. doi: 10.1186/s12887-018-1255-z |
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2018 Journal Article Salbutamol-induced Decrease in Augmentation Index is Related to the Parallel Increase in Heart RateTikkakoski, Antti J., Kangas, Pauliina, Suojanen, Lauri, Tahvanainen, Anna M., Eraranta, Arttu, Kahonen, Mika A. P., Sipila, Kalle, Mustonen, Jukka T. and Porsti, Ilkka H. (2018). Salbutamol-induced Decrease in Augmentation Index is Related to the Parallel Increase in Heart Rate. Basic & Clinical Pharmacology & Toxicology, 123 (2), 161-173. doi: 10.1111/bcpt.12988 |
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2018 Journal Article Age at first birth in women is genetically associated with increased risk of schizophreniaNi, Guiyan, Gratten, Jacob, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Wray, Naomi R. and Lee, Sang Hong (2018). Age at first birth in women is genetically associated with increased risk of schizophrenia. Scientific Reports, 8 (1) 10168, 10168. doi: 10.1038/s41598-018-28160-z |
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2018 Journal Article Serum proteomic profiling to identify biomarkers of premature carotid atherosclerosisBhosale, Santosh D., Moulder, Robert, Venalainen, Mikko S., Koskinen, Juhani S., Pitkanen, Niina, Juonala, Markus T., Kahonen, Mika A. P., Lehtimaki, Terho J., Viikari, Jorma S. A., Elo, Laura L., Goodlett, David R., Lahesmaa, Riitta and Raitakari, Olli T. (2018). Serum proteomic profiling to identify biomarkers of premature carotid atherosclerosis. Scientific Reports, 8 (1) 9209. doi: 10.1038/s41598-018-27265-9 |
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2018 Journal Article Trans-eQTLs identified in whole blood have limited influence on complex disease biologyYap, Chloe X., Lloyd-Jones, Luke, Holloway, Alexander, Smartt, Peter, Wray, Naomi R., Gratten, Jacob and Powell, Joseph E. (2018). Trans-eQTLs identified in whole blood have limited influence on complex disease biology. European Journal of Human Genetics, 26 (9), 1-8. doi: 10.1038/s41431-018-0174-7 |
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2018 Journal Article Sizing up whole-genome sequencing studies of common diseasesWray, Naomi R. and Gratten, Jacob (2018). Sizing up whole-genome sequencing studies of common diseases. Nature Genetics, 50 (5), 635-637. doi: 10.1038/s41588-018-0113-0 |
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2018 Conference Publication Critical Periods in Cardiovascular Health Across the Life Course: A Pooled Cohort AnalysisAllen, Norrina B., Krefman, Amy, Labarthe, Darwin, Greenland, Philip, Juonala, Markus, Kahonen, Mika, Day, S. Rena, Lehtimaki, Terho, Van Horn, Linda, Bazzano, Lydia, Liu, Lei, Alonso, Camilo F., Webber, Larry S., Pahkala, Katja, Laitinen, Tomi, Raitakari, Olli and Lloyd-Jones, Donald (2018). Critical Periods in Cardiovascular Health Across the Life Course: A Pooled Cohort Analysis. Scientific Sessions of the American-Heart-Association on Epidemiology and Prevention/Lifestyle and Cardiometabolic Health, New Orleans La, Mar 20-23, 2018. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. |
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2018 Journal Article Sugar-sweetened beverage intake associations with fasting glucose and insulin concentrations are not modified by selected genetic variants in a ChREBP-FGF21 pathway: a meta-analysisMcKeown, Nicola M., Dashti, Hassan S., Ma, Jiantao, Haslam, Danielle E., Kiefte-de Jong, Jessica C., Smith, Caren E., Tanaka, Toshiko, Graff, Mariaelisa, Lemaitre, Rozenn N., Rybin, Denis, Sonestedt, Emily, Frazier-Wood, Alexis C., Mook-Kanamori, Dennis O., Li, Yanping, Wang, Carol A., Leermakers, Elisabeth T. M., Mikkila, Vera, Young, Kristin L., Mukamal, Kenneth J., Cupples, L. Adrienne, Schulz, Christina-Alexandra, Chen, Tzu-An, Li-Gao, Ruifang, Huang, Tao, Oddy, Wendy H., Raitakari, Olli, Rice, Kenneth, Meigs, James B., Ericson, Ulrika ... Herman, Mark A. (2018). Sugar-sweetened beverage intake associations with fasting glucose and insulin concentrations are not modified by selected genetic variants in a ChREBP-FGF21 pathway: a meta-analysis. Diabetologia, 61 (2), 317-330. doi: 10.1007/s00125-017-4475-0 |
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2017 Journal Article Gene networks associated with non-syndromic intellectual disabilityLee, Soohyun, Rudd, Stephen, Gratten, Jacob, Visscher, Peter M., Prins, Johannes B. and Dawson, Paul A. (2017). Gene networks associated with non-syndromic intellectual disability. Journal of Neurogenetics, 32 (1), 6-14. doi: 10.1080/01677063.2017.1404058 |
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2017 Journal Article Whole-exome sequencing in amyotrophic lateral sclerosis suggests NEK1 is a risk gene in ChineseGratten, Jacob, Zhao, Qiongyi, Benyamin, Beben, Garton, Fleur, He, Ji, Leo, Paul J., Mangelsdorf, Marie, Anderson, Lisa, Zhang, Zong-Hong, Chen, Lu, Chen, Xiang-Ding, Cremin, Katie, Deng, Hong-Weng, Edson, Janette, Han, Ying-Ying, Harris, Jessica, Henders, Anjali K., Jin, Zi-Bing, Li, Zhongshan, Lin, Yong, Liu, Xiaolu, Marshall, Mhairi, Mowry, Bryan J., Ran, Shu, Reutens, David C., Song, Sharon, Tan, Li-Jun, Tang, Lu, Wallace, Robyn H. ... Fan, Dongsheng (2017). Whole-exome sequencing in amyotrophic lateral sclerosis suggests NEK1 is a risk gene in Chinese. Genome Medicine, 9 (97) 97, 97. doi: 10.1186/s13073-017-0487-0 |
