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2023 Journal Article Endocytosis in cancer and cancer therapyBanushi, Blerida, Joseph, Shannon R., Lum, Benedict, Lee, Jason J. and Simpson, Fiona (2023). Endocytosis in cancer and cancer therapy. Nature Reviews Cancer, 23 (7), 1-24. doi: 10.1038/s41568-023-00574-6 |
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2024 Journal Article Gastrointestinal metastasis of breast cancer: exploring the path aheadZhao, Peng-Yue, Zhao, Zhen-Ting, Li, Song-Yan, Simpson, Fiona and Du, Xiao-Hui (2024). Gastrointestinal metastasis of breast cancer: exploring the path ahead. Medicine Plus, 1 (4) 100055, 100055. doi: 10.1016/j.medp.2024.100055 |
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2024 Journal Article Fibroblast activation protein (FAP) is overexpressed on both stromal and epithelial cells prior to pancreatic ductal adenocarcinoma: implications for early diagnosis on 68Ga-FAPI-PET/CTMcGahan, William, Gough, Madeline, Liu, Cheng, Hoyte, Sharon, Gill, Anthony J., Cavallucci, David, Australian Pancreatic Cancer Genome Initiative, Hooper, John D., Thomas, Paul A., Cooper, Caroline, O'Rourke, Thomas, Butler, Nick, Yeung, Shinn, Kryza, Thomas, Gulhane, Brook, Latter, Melissa J., Waddell, Nicola, Samra, Jaswinder S., Simpson, Fiona and Pajic, Marina (2024). Fibroblast activation protein (FAP) is overexpressed on both stromal and epithelial cells prior to pancreatic ductal adenocarcinoma: implications for early diagnosis on 68Ga-FAPI-PET/CT. Gastroenterology, 167 (6), 1217-1220. doi: 10.1053/j.gastro.2024.06.033 |
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2024 Journal Article TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancerWong, Joshua K. M., McCulloch, Timothy R., Alim, Louisa, Omer, Natacha, Mehdi, Ahmed M., Tuong, Zewen Kelvin, Bonfim-Melo, Alexis, Chung, Eric, Nicol, Alice, Simpson, Fiona, Rhee, Handoo, Rossi, Gustavo Rodrigues and Souza-Fonseca-Guimaraes, Fernando (2024). TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancer. EBioMedicine, 104 105176. doi: 10.1016/j.ebiom.2024.105176 |
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2024 Journal Article Antibody dependent cellular cytotoxicity-inducing anti-EGFR antibodies as effective therapeutic option for cutaneous melanoma resistant to BRAF inhibitorsMuraro, Elena, Montico, Barbara, Lum, Benedict, Colizzi, Francesca, Giurato, Giorgio, Salvati, Annamaria, Guerrieri, Roberto, Rizzo, Aurora, Comaro, Elisa, Canzonieri, Vincenzo, Anichini, Andrea, Del Vecchio, Michele, Mortarini, Roberta, Milione, Massimo, Weisz, Alessandro, Pizzichetta, Maria Antonietta, Simpson, Fiona, Dolcetti, Riccardo, Fratta, Elisabetta and Sigalotti, Luca (2024). Antibody dependent cellular cytotoxicity-inducing anti-EGFR antibodies as effective therapeutic option for cutaneous melanoma resistant to BRAF inhibitors. Frontiers in Immunology, 15 1336566, 1-17. doi: 10.3389/fimmu.2024.1336566 |
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2024 Journal Article A PEGylated liposomal formulation of prochlorperazine that limits brain exposure but retains dynamin II activity: A potential adjuvant therapy for cancer patients receiving chemotherapeutic mAbsSubasic, Christopher N., Simpson, Fiona, Minchin, Rodney F. and Kaminskas, Lisa M. (2024). A PEGylated liposomal formulation of prochlorperazine that limits brain exposure but retains dynamin II activity: A potential adjuvant therapy for cancer patients receiving chemotherapeutic mAbs. Nanomedicine: Nanotechnology, Biology and Medicine, 56 102733, 1-8. doi: 10.1016/j.nano.2024.102733 |
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2024 Journal Article Steroid premedication and monoclonal antibody therapy: should we reconsider?Karlsen, Emma-Anne, Walpole, Euan and Simpson, Fiona (2024). Steroid premedication and monoclonal antibody therapy: should we reconsider?. Current Treatment Options in Oncology, 25 (3), 275-283. doi: 10.1007/s11864-023-01170-4 |
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2023 Journal Article Epidermal growth factor potentiates EGFR(Y992/1173)-mediated therapeutic response of triple negative breast cancer cells to cold atmospheric plasma-activated mediumWang, Peiyu, Zhou, Renwu, Zhou, Rusen, Feng, Shuo, Zhao, Liqian, Li, Wenshao, Lin, Jinyong, Rajapakse, Aleksandra, Lee, Chia-Hwa, Furnari, Frank B., Burgess, Antony W., Gunter, Jennifer H., Liu, Gang, Ostrikov, Kostya (Ken), Richard, Derek J., Simpson, Fiona, Dai, Xiaofeng and Thompson, Erik W. (2023). Epidermal growth factor potentiates EGFR(Y992/1173)-mediated therapeutic response of triple negative breast cancer cells to cold atmospheric plasma-activated medium. Redox Biology, 69 102976, 102976. doi: 10.1016/j.redox.2023.102976 |
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2023 Journal Article Development of an in vivo murine model of perineural invasion and spread of cutaneous squamous cell carcinoma of the head and neckde Lima, Priscila O., Broit, Natasa, Huang, Johnson D., Lim, Jae H., Gardiner, Damien J., Brown, Ian S., Panizza, Benedict J., Boyle, Glen M. and Simpson, Fiona (2023). Development of an in vivo murine model of perineural invasion and spread of cutaneous squamous cell carcinoma of the head and neck. Frontiers in Oncology, 13 1231104, 1-16. doi: 10.3389/fonc.2023.1231104 |
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2023 Journal Article Dose-dependent effect of phenothiazines as dynamin II inhibitors on the uptake of PEGylated liposomes by endocytic cells and in vivo pharmacokinetics of PEGylated liposomal doxorubicin in ratsSubasic, Christopher N., Butcher, Neville J., Simpson, Fiona, Minchin, Rodney F. and Kaminskas, Lisa M. (2023). Dose-dependent effect of phenothiazines as dynamin II inhibitors on the uptake of PEGylated liposomes by endocytic cells and in vivo pharmacokinetics of PEGylated liposomal doxorubicin in rats. Molecular Pharmaceutics, 20 (9), 4468-4477. doi: 10.1021/acs.molpharmaceut.3c00102 |
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2023 Journal Article Weaponizing natural killer cells for solid cancer immunotherapyWong, Joshua K.M., Dolcetti, Riccardo, Rhee, Handoo, Simpson, Fiona and Souza-Fonseca-Guimaraes, Fernando (2023). Weaponizing natural killer cells for solid cancer immunotherapy. Trends in Cancer, 9 (2), 111-121. doi: 10.1016/j.trecan.2022.10.009 |
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2022 Journal Article Overlapping machinery in lysosome-related organelle trafficking: a lesson from rare multisystem disordersBanushi, Blerida and Simpson, Fiona (2022). Overlapping machinery in lysosome-related organelle trafficking: a lesson from rare multisystem disorders. Cells, 11 (22) 3702, 1-26. doi: 10.3390/cells11223702 |
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2022 Journal Article Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophagesTran, Thao Thanh, Mathmann, Carmen D., Gatica-Andrades, Marcela, Rollo, Rachel F., Oelker, Melanie, Ljungberg, Johanna K., Nguyen, Tam T. K., Zamoshnikova, Alina, Kummari, Lalith K., Wyer, Orry J. K., Irvine, Katharine M., Melo-Bolívar, Javier, Gross, Annette, Brown, Darren, Mak, Jeffrey Y. W., Fairlie, David P., Hansford, Karl A., Cooper, Matthew A., Giri, Rabina, Schreiber, Veronika, Joseph, Shannon R., Simpson, Fiona, Barnett, Timothy C., Johansson, Jörgen, Dankers, Wendy, Harris, James, Wells, Timothy J., Kapetanovic, Ronan, Sweet, Matthew J. ... Blumenthal, Antje (2022). Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages. PLoS Pathogens, 18 (1) e1010166, e1010166. doi: 10.1371/journal.ppat.1010166 |
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2021 Journal Article Germline ERBB3 mutation in familial non-small cell lung carcinoma: expanding ErbB’s role in oncogenesisMcInerney-Leo, Aideen M., Chew, Hui Yi, Inglis, Po-Ling, Leo, Paul J., Joseph, Shannon R., Cooper, Caroline L., Okano, Satomi, Hassall, Tim, Anderson, Lisa, Bowman, Rayleen V., Gattas, Michael, Harris, Jessica E., Marshall, Mhairi S., Shaw, Janet G., Wheeler, Lawrie, Yang, Ian A., Brown, Matthew A., Fong, Kwun M., Simpson, Fiona and Duncan, Emma L. (2021). Germline ERBB3 mutation in familial non-small cell lung carcinoma: expanding ErbB’s role in oncogenesis. Human Molecular Genetics, 30 (24), 2393-2401. doi: 10.1093/hmg/ddab172 |
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2021 Journal Article Evolution of cancer vaccines—challenges, achievements and future directionsTay, Ban Qi, Wright, Quentin, Ladwa, Rahul, Perry, Christopher, Leggatt, Graham, Simpson, Fiona, Wells, James W., Panizza, Benedict J., Frazer, Ian H. and Cruz, Jazmina L. G. (2021). Evolution of cancer vaccines—challenges, achievements and future directions. Vaccines, 9 (5) 535, 535. doi: 10.3390/vaccines9050535 |
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2021 Journal Article Epidermal growth factor receptor expression and resistance patterns to targeted therapy in non-small cell lung cancer: a reviewKarlsen, Emma-Anne, Kahler, Sam, Tefay, Joan, Joseph, Shannon R. and Simpson, Fiona (2021). Epidermal growth factor receptor expression and resistance patterns to targeted therapy in non-small cell lung cancer: a review. Cells, 10 (5) 1206, 1206. doi: 10.3390/cells10051206 |
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2021 Journal Article Adenoid cystic carcinoma: a review of clinical features, treatment targets and advancement in improving the immune response to monoclonal antibody therapyNightingale, James, Lum, Benedict, Ladwa, Rahul, Simpson, Fiona and Panizza, Benedict (2021). Adenoid cystic carcinoma: a review of clinical features, treatment targets and advancement in improving the immune response to monoclonal antibody therapy. Biochimica et Biophysica Acta. Reviews on Cancer, 1875 (2) 188523, 1-9. doi: 10.1016/j.bbcan.2021.188523 |
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2020 Journal Article Therapeutic implications of immune-profiling and EGFR expression in salivary gland carcinomaGuazzo, Emily, Cooper, Caroline, Wilkinson, Lisa, Feng, Sophie, King, Brigid, Simpson, Fiona, Porceddu, Sandro, Panizza, Benedict and Coward, Jermaine I G (2020). Therapeutic implications of immune-profiling and EGFR expression in salivary gland carcinoma. Head and neck, 43 (3) hed.26529, 768-777. doi: 10.1002/hed.26529 |
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2020 Journal Article Will next-generation immunotherapy overcome the intrinsic diversity and low immunogenicity of sarcomas to improve clinical benefit?Chew, Hui Yi, Chan, Victor, Simpson, Fiona and Dolcetti, Riccardo (2020). Will next-generation immunotherapy overcome the intrinsic diversity and low immunogenicity of sarcomas to improve clinical benefit?. Cancers, 12 (11) 3392, 1-29. doi: 10.3390/cancers12113392 |
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2020 Journal Article Cetuximab exhibits sex differences in lymphatic exposure after intravenous administration in rats in the absence of differences in plasma exposureKuilamu, Esther, Subasic, Christopher, Cowin, Gary J., Simpson, Fiona, Minchin, Rodney F. and Kaminskas, Lisa M. (2020). Cetuximab exhibits sex differences in lymphatic exposure after intravenous administration in rats in the absence of differences in plasma exposure. Pharmaceutical Research, 37 (11) 224, 1-12. doi: 10.1007/s11095-020-02945-2 |
