Overview
Background
Dr. Zhen Zhang specializes in developing advanced nanotechnology platforms for diagnosing cancers and other pathologies through liquid biopsy. Her research integrates expertise in nanotechnology, bioengineering, and analytical chemistry to create innovative solutions for early detection and disease monitoring. By leveraging cutting-edge techniques such as microfluidics and surface-enhanced Raman spectroscopy (SERS), Dr. Zhang's work aims to enhance the sensitivity and specificity of liquid biopsy methods. Her multidisciplinary approach focuses on translating these technologies into clinical applications, advancing precision medicine for cancer and other complex diseases.
Availability
- Dr Zhen Zhang is:
- Available for supervision
Qualifications
- Doctor of Philosophy of Technology in Medical Nanotechnology, The University of Queensland
Works
Search Professor Zhen Zhang’s works on UQ eSpace
2025
Journal Article
The emerging role of glycolysis and immune evasion in ovarian cancer
Jin, Bowen, Miao, Zehua, Pan, Junjie, Zhang, Zhen, Yang, Yibei, Zhou, Yidong, Jin, Yuanxiang, Niu, Zheng and Xu, Qiaoping (2025). The emerging role of glycolysis and immune evasion in ovarian cancer. Cancer Cell International , 25 (1) 78, 1. doi: 10.1186/s12935-025-03698-x
2025
Journal Article
Conventional techniques and emerging nanotechnologies for early detection of cancer metastasis via epithelial-mesenchymal transition monitoring
Zhang, Zhen, Wang, Jing, Wuethrich, Alain and Trau, Matt (2025). Conventional techniques and emerging nanotechnologies for early detection of cancer metastasis via epithelial-mesenchymal transition monitoring. National Science Review, 12 (3) nwae452, 1-17. doi: 10.1093/nsr/nwae452
2024
Journal Article
Glycan profiling in small extracellular vesicles with a SERS microfluidic biosensor identifies early malignant development in lung cancer
Zhou, Quan, Niu, Xueming, Zhang, Zhen, O'Byrne, Kenneth, Kulasinghe, Arutha, Fielding, David, Möller, Andreas, Wuethrich, Alain, Lobb, Richard J. and Trau, Matt (2024). Glycan profiling in small extracellular vesicles with a SERS microfluidic biosensor identifies early malignant development in lung cancer. Advanced Science, 11 (33) 2401818, 1-12. doi: 10.1002/advs.202401818
2024
Journal Article
Analysis of secreted small extracellular vesicles from activated human microglial cell lines reveals distinct pro‐ and anti‐inflammatory proteomic profiles
Niu, Xueming, Zhang, Zhen, Zhou, Quan, Wuethrich, Alain, Lobb, Richard and Trau, Matt (2024). Analysis of secreted small extracellular vesicles from activated human microglial cell lines reveals distinct pro‐ and anti‐inflammatory proteomic profiles. Proteomics, 24 (11) 2300094, 1-13. doi: 10.1002/pmic.202300094
2024
Journal Article
Digital platforms enabling single-molecule analysis for cancer detection
Li, Junrong, Zhang, Zhen, Trau, Matt and Wuethrich, Alain (2024). Digital platforms enabling single-molecule analysis for cancer detection. TrAC Trends in Analytical Chemistry, 171 117502, 1-12. doi: 10.1016/j.trac.2023.117502
2024
Journal Article
Tracking the EMT-like phenotype switching during targeted therapy in melanoma by analyzing extracellular vesicle phenotypes
Zhou, Quan, Wang, Jing, Zhang, Zhen, Wuethrich, Alain, Lobb, Richard J. and Trau, Matt (2024). Tracking the EMT-like phenotype switching during targeted therapy in melanoma by analyzing extracellular vesicle phenotypes. Biosensors and Bioelectronics, 244 115819, 1-10. doi: 10.1016/j.bios.2023.115819
2023
Journal Article
Multiplex SERS-lectin-immunoassay for esophageal adenocarcinoma screening
Khamis, Ramlah, Shanmugasundaram, Karthik B., Zhou, Quan, Lu, Jennifer, Zhang, Zhen, Hill, Michelle M., Sina, Abu Ali Ibn, Trau, Matt and Wuethrich, Alain (2023). Multiplex SERS-lectin-immunoassay for esophageal adenocarcinoma screening. ACS Applied Nano Materials, 6 (21), 20190-20197. doi: 10.1021/acsanm.3c03987
2023
Other Outputs
Precision nano-diagnostics for dynamically profiling glioblastoma multiforme and the epithelial-mesenchymal transition in cancer
Zhang, Zhen (2023). Precision nano-diagnostics for dynamically profiling glioblastoma multiforme and the epithelial-mesenchymal transition in cancer. PhD Thesis, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland. doi: 10.14264/5c170e7
2022
Journal Article
SERS multiplex profiling of melanoma circulating tumor cells for predicting the response to immune checkpoint blockade therapy
Li, Junrong, Wuethrich, Alain, Zhang, Zhen, Wang, Jing, Lin, Lynlee L., Behren, Andreas, Wang, Yuling and Trau, Matt (2022). SERS multiplex profiling of melanoma circulating tumor cells for predicting the response to immune checkpoint blockade therapy. Analytical Chemistry, 94 (42), 14573-14582. doi: 10.1021/acs.analchem.2c02398
2021
Journal Article
Dynamic monitoring of EMT in CTCs as an indicator of cancer metastasis
Zhang, Zhen, Wuethrich, Alain, Wang, Jing, Korbie, Darren, Lin, Lynlee L. and Trau, Matt (2021). Dynamic monitoring of EMT in CTCs as an indicator of cancer metastasis. Analytical Chemistry, 93 (50) acs.analchem.1c03167, 16787-16795. doi: 10.1021/acs.analchem.1c03167
2020
Journal Article
Tracking drug-induced epithelial–mesenchymal transition in breast cancer by a microfluidic surface-enhanced raman spectroscopy immunoassay
Zhang, Zhen, Wang, Jing, Shanmugasundaram, Karthik Balaji, Yeo, Belinda, Möller, Andreas, Wuethrich, Alain, Lin, Lynlee L. and Trau, Matt (2020). Tracking drug-induced epithelial–mesenchymal transition in breast cancer by a microfluidic surface-enhanced raman spectroscopy immunoassay. Small, 16 (13) 1905614, e1905614. doi: 10.1002/smll.201905614
2020
Journal Article
Ultrasensitive melanoma biomarker detection using a microchip SERS immunoassay with anisotropic Au–Ag alloy nanoboxes
Kumar, Aswin Raj, Shanmugasundaram, Karthik Balaji, Li, Junrong, Zhang, Zhen, Ibn Sina, Abu Ali, Wuethrich, Alain and Trau, Matt (2020). Ultrasensitive melanoma biomarker detection using a microchip SERS immunoassay with anisotropic Au–Ag alloy nanoboxes. RSC Advances, 10 (48), 28778-28785. doi: 10.1039/d0ra05032f
2015
Journal Article
Implications of ghrelin and hexarelin in diabetes and diabetes-associated heart diseases
Mosa, Rasha Mofeed Habeeb, Zhang, Zhen, Shao, Renfu, Deng, Chao, Chen, Jiezhong and Chen, Chen (2015). Implications of ghrelin and hexarelin in diabetes and diabetes-associated heart diseases. Endocrine, 49 (2), 307-323. doi: 10.1007/s12020-015-0531-z
Supervision
Availability
- Dr Zhen Zhang is:
- Available for supervision
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Media
Enquiries
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