Overview
Background
Dr. Lachlan McDowell (B.App.Sc, MB BS, FRANZCR, PhD) is a radiation oncologist and clinical researcher specializing in head and neck cancer (HNC), with a focus on human papillomavirus-associated oropharyngeal cancer (HPV-OPC). His work combines clinical expertise with innovative research to improve patient outcomes and quality of life.
Dr. Lachlan McDowell's research addresses critical aspects of HNC including:
- Identifying latent patterns of quality of life in cancer survivors
- Understanding the differing impacts of different radiation treatments
- Understanding and quantifying unmet needs in HNC survivors, including sexual health, emotional distress, fear of cancer recurrence and return to work
He completed his PhD at the University of Melbourne in 2024 with a Dean’s Research Award.
A significant part of his academic contributions comes from secondary analyses of clinical trials, such as TROG 12.01, which provide valuable insights into the evolving management of HPV-OPC cancers. Dr. McDowell also collaborates internationally and has developed an emerging global profile in head and neck oncology through his editorial roles and positions in the Trans Tasman Radiation Oncology Group (TROG) and the Head and Neck Cancer International Group (HNCIG)
Keywords: head and neck cancer, HPV-associated oropharyngeal cancer, radiation oncology, survivorship, quality of life, sexual health, TROG, clinical trials.
Availability
- Dr Lachlan McDowell is:
- Available for supervision
Qualifications
- Doctor of Philosophy of Oncology, University of Melbourne
Works
Search Professor Lachlan McDowell’s works on UQ eSpace
2024
Journal Article
Sexual Health, sexuality and sexual intimacy in patients with head and neck cancer – a narrative review
McDowell, Lachlan, Gough, Karla, White, Isabel, Corry, June and Rischin, Danny (2024). Sexual Health, sexuality and sexual intimacy in patients with head and neck cancer – a narrative review. Oral Oncology, 157 106975, 106975. doi: 10.1016/j.oraloncology.2024.106975
2024
Journal Article
Assessment of endpoint definitions in curative-intenttrials for mucosal head and neck squamous cell carcinomas: Head and Neck Cancer International Group consensus recommendations
Lim, Annette M., McDowell, Lachlan, Hurt, Chris, Le Tourneau, Christophe, Homma, Akihiro, Shenouda, George, Thomson, David J., Moya-Plana, Antoine, Henson, Christina, Szturz, Petr, Day, Andrew, Bates, James E., Lazarakis, Smaro, Thariat, Juliette, Psyrri, Amanda, Mehanna, Hisham, Yom, Sue S. and HNCIG, on behalf of the (2024). Assessment of endpoint definitions in curative-intenttrials for mucosal head and neck squamous cell carcinomas: Head and Neck Cancer International Group consensus recommendations. Lancet Oncology, 25 (7), e318-e330.
2024
Journal Article
Assessment of endpoint definitions in curative-intent trials for mucosal head and neck squamous cell carcinomas: Head and Neck Cancer International Group consensus recommendations
Lim, Annette M, McDowell, Lachlan, Hurt, Chris, Le Tourneau, Christophe, Homma, Akihiro, Shenouda, George, Thomson, David J, Moya-Plana, Antoine, Henson, Christina, Szturz, Petr, Day, Andrew T, Bates, James E, Lazarakis, Smaro, Thariat, Juliette, Psyrri, Amanda, Mehanna, Hisham and Yom, Sue S (2024). Assessment of endpoint definitions in curative-intent trials for mucosal head and neck squamous cell carcinomas: Head and Neck Cancer International Group consensus recommendations. The Lancet Oncology, 25 (7), e318-e330. doi: 10.1016/S1470-2045(24)00067-6
2024
Journal Article
Assessment of endpoint definitions in recurrent and metastatic mucosal head and neck squamous cell carcinoma trials: Head and Neck Cancer International Group consensus recommendations
Lim, Annette M, Le Tourneau, Christophe, Hurt, Chris, Laskar, Sarbani G, Steuer, Conor E, Chow, Velda L Y, Szturz, Petr, Henson, Christina, Day, Andrew T, Bates, James E, Lazarakis, Smaro, McDowell, Lachlan, Mehanna, Hisham and Yom, Sue S (2024). Assessment of endpoint definitions in recurrent and metastatic mucosal head and neck squamous cell carcinoma trials: Head and Neck Cancer International Group consensus recommendations. The Lancet Oncology, 25 (7), e308-e317. doi: 10.1016/S1470-2045(24)00068-8
2024
Journal Article
Criteria for the diagnosis of extranodal extension detected on radiological imaging in head and neck cancer: Head and Neck Cancer International Group consensus recommendations
Henson, Christina, Abou-Foul, Ahmad K, Yu, Eugene, Glastonbury, Christine, Huang, Shao Hui, King, Ann D., Lydiatt, William M., McDowell, Lachlan, Nagelschneider, Alex A., Nankivell, Paul C., O'Sullivan, Brian, Rhys, Rhian, Xiao, Youping, Andrew, David, Asmussen, Jon T., Bidault, Francois, Dankbaar, Jan W., de Graaf, Pim, Gebrim, Eloisa S., Hu, Chaosu, Ding, Jianhui, Kanda, Tomonori, Kim, Jane, Kuno, Hirofumi, Medrano-Martorell, Santiago, Oikonomopoulos, Nikolaos, Goh, Julian Park-Nam, Santos-Armentia, Eloisa, Schafigh, Darius G. ... Mehanna, Hisham (2024). Criteria for the diagnosis of extranodal extension detected on radiological imaging in head and neck cancer: Head and Neck Cancer International Group consensus recommendations. The Lancet Oncology, 25 (7), e297-e307. doi: 10.1016/S1470-2045(24)00066-4
2024
Journal Article
Essential data variables for a minimum dataset for head and neck cancer trials and clinical research: HNCIG consensus recommendations and database
Baliga, Sujith, Abou-Foul, Ahmad K., Parente, Pablo, Szturz, Petr, Thariat, Juliette, Shreenivas, Aditya, Nankivell, Paul, Bertolini, Federica, Biau, Julian, Blakaj, Dukagjin, Brennan, Sinead, Brunet, Aina, De Oliveira, Thiago Bueno, Burtness, Barbara, Maseda, Alberto Carral, Chow, Velda Ling-Yu, Chua, Melvin LK, de Ridder, Mischa, Garikipati, Satya, Hanai, Nobuhiro, Ho, Francis Cho Hao, Huang, Shao Hui, Kiyota, Naomi, Klinghammer, Konrad, Kowalski, Luiz P., Kwong, Dora L, McDowell, Lachlan J, Merlano, Marco Carlo, Nair, Sudhir ... Mehanna, Hisham (2024). Essential data variables for a minimum dataset for head and neck cancer trials and clinical research: HNCIG consensus recommendations and database. European Journal of Cancer, 203 114038. doi: 10.1016/j.ejca.2024.114038
2024
Journal Article
Carotid artery stenosis and ischemic stroke in patients with head and neck cancer treated with radiotherapy: a critical review
Smith, Justin, Margalit, Danielle, Golledge, Jonathan, Nastasi, Domenico, Nohria, Anju and McDowell, Lachlan (2024). Carotid artery stenosis and ischemic stroke in patients with head and neck cancer treated with radiotherapy: a critical review. International Journal of Radiation: Oncology - Biology - Physics, 119 (5), 1437-1454. doi: 10.1016/j.ijrobp.2024.03.044
2023
Journal Article
Patient-Reported Symptom Severity, Health-Related Quality of Life, and Emotional Distress Trajectories During and After Radiation Therapy for Human Papillomavirus–Associated Oropharyngeal Cancer: A TROG 12.01 Secondary Analysis
McDowell, Lachlan, Bressel, Mathias, King, Madeleine T., Corry, June, Kenny, Lizbeth, Porceddu, Sandro, Wratten, Christopher, Macann, Andrew, Jackson, James E. and Rischin, Danny (2023). Patient-Reported Symptom Severity, Health-Related Quality of Life, and Emotional Distress Trajectories During and After Radiation Therapy for Human Papillomavirus–Associated Oropharyngeal Cancer: A TROG 12.01 Secondary Analysis. International Journal of Radiation Oncology Biology Physics, 116 (5), 1110-1125. doi: 10.1016/j.ijrobp.2023.02.041
Supervision
Availability
- Dr Lachlan McDowell is:
- Available for supervision
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Supervision history
Current supervision
-
Master Philosophy
PET images as predictor of outcome following Radiotherapy
Associate Advisor
Other advisors: Dr Lena Oestreich
Media
Enquiries
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