Overview
Background
About & Research Focus
Associate Professor Sheila Cecily Ommeh is a computational biologist, and biotechnology specialist with over three decades of research leadership spanning infectious disease dynamics, multi-omics, and translational biosecurity at the One Health interface. Her research program focuses on the rational design of next-generation biodetection platforms, point-of-care diagnostics, novel therapeutics, modern livestock vaccine platforms to safeguard animal production systems, biosecurity, and food security and exploring animal biodiversity for resillience.
Career Journey & Scientific Heritage
Born on the slopes of Mount Elgon—an extinct volcano straddling Kenya and Uganda—she grew up on the foothills with her grandmother, a smallholder farmer. Witnessing early on the devastating impacts of infectious diseases and climatic extremes on rural livestock and community livelihoods shaped her dedication to agricultural resilience and veterinary health. She was profoundly inspired and mentored by her late mother, an accomplished scientist and visionary leader who fostered her early career in STEM.
A seasoned research strategist, A/Prof Ommeh brings extensive experience establishing, funding, and directing large-scale, multidisciplinary initiatives across global academic consortia and international research networks. Her leadership unites computational biologists, field researchers, veterinary authorities, and cross-sectoral collaborator seamlessly aligning diverse teams to translate fundamental discovery science into robust research frameworks, policy-informing datasets, and durable institutional research capacity. Her scientific journey over the past 30 years encompasses a comprehensive One Health continuum across leading global research centres:
-
Vector-Borne Human Pathogens: Commenced research at the Kenya Medical Research Institute (KEMRI) investigating Leishmania, subsequently advancing to human malaria molecular epidemiology with the KEMRI–Wellcome Trust Research Programme.
-
Livestock Genomics & Biodiversity: Transitioned to agricultural biotechnology at the International Livestock Research Institute (ILRI), Seoul National University (Republic of Korea) and Paco Tecnologico Padano (Italy), focusing on avian genetics, viral disease resistance, and livestock adaptive resilience.
-
Pathogen Surveillance & Wildlife Interfaces: At Jomo Kenyatta University of Agriculture and Technology (JKUAT), she led the Animal Biotechnology Research Group at the Institute for Biotechnology Research (IBR). Her work spearheaded research on several indigenous poultry species and emerging livestock species. She also expanded into broad-scale pathogen surveillance, viral genomics, and biodiversity characterization across multi-species ecosystems; including domesticates, wildlife reservoirs, and vector populations with collaborators from the Chinese Academy of Sciences (China), University of Hasselt (Belgium) and Pirbright institute (UK) among other international collaborations.
Postgraduate Supervision & Student Opportunities
A dedicated academic mentor and educator, A/Prof Ommeh has supervised over 20 Higher Degree by Research Scholars (HDRs) to successful completion.
She actively welcomes prospective PhD, MPhil, and Honours students, as well as postdoctoral fellows, with backgrounds or interests in:
-
Computational Biology & Bioinformatics: Genomic pipelines, molecular phylodynamics, and pathogen evolution.
-
Molecular Biosecurity & Next-Generation Diagnostics: Translation of molecular and deep-tech sensing platforms for rapid, remote field detection.
-
Rational Vaccine & Therapeutic Design: Computational epitope mapping and modern platform engineering for high-impact veterinary diseases.
-
One Health & Animal Biodiversity: Exploring adaptive traits, disease tolerance, and resilient emerging protein resources.
Students joining the research group gain hands-on expertise in interdisciplinary computational pipelines, multi-omics, advanced genomic sequencing, and translational animal health biosecurity, benefiting from strong international networks and industry-aligned research environments.
Availability
- Associate Professor Sheila Ommeh is:
- Available for supervision
Qualifications
- Doctor of Philosophy, Tuscia University
Research interests
-
Point-of-Care Diagnostics and Molecular Biosecurity
Developing ruggedized, rapid biodetection platforms tailored for remote livestock production systems and wildlife interfaces. This research integrates advanced molecular assays, biosensing modalities, and field-ready nucleic acid detection to identify notifiable animal pathogens crush-side. The aim is to deliver actionable diagnostic intelligence within minutes to protect agricultural economies, mitigate outbreak impacts, and safeguard international livestock trade.
-
Viral Genomics and Molecular Phylodynamics
Applying high-throughput computational biology and long-read sequencing technologies to track infectious disease transmission dynamics across species boundaries. This work investigates viral evolutionary trajectories, pathogen diversity, and molecular epidemiology at the human-animal-wildlife interface. Research outputs establish robust early-warning surveillance frameworks to identify zoonotic risks, trace transmission pathways, and inform national and regional biosecurity decision-making.
-
Rational Vaccine Design: 'in silico' approach
Leveraging reverse genetics, computational epitope mapping, and structural bioinformatics to engineer next-generation veterinary vaccines and targeted therapeutics. The primary objective is constructing safe, marker-compliant platforms that differentiate infected from vaccinated animals (DIVA). These interventions address priority livestock diseases while preserving trade status and advancing durable herd immunity without conventional cold-chain constraints.
-
One Health and Resilient Animal Genetic Resources
Characterising the genetic diversity, disease tolerance, and climate adaptation traits of indigenous and emerging livestock species. Employing population genomics and functional annotation, this research uncovers candidate genes linked to heat resilience and pathogen resistance. The program supports sustainable protein diversification, pastoralist livelihoods, and climate-resilient agricultural systems through collaborative One Health frameworks.
Research impacts
Infectious disease outbreaks in livestock threaten national biosecurity, food security, and primary producer livelihoods. Associate Professor Sheila Ommeh’s research translates advanced computational biology, long-read sequencing, and next-generation biodetection platforms into practical, field-ready biosecurity tools that protect livestock industries, rural communities, and export markets.
Her research delivers tangible impacts across four key areas:
Safeguarding Agricultural Economies and Biosecurity
-
Early Outbreak Interception: Developing rapid, point-of-care diagnostic and biodetection platforms enables animal health officers and producers to identify notifiable diseases crush-side within minutes rather than waiting days for centralised laboratory clearance, directly reducing containment costs during disease incursions.
-
Protecting Export Trade Status: Rationally designing differentiating vaccine platforms (DIVA compliance) ensures livestock herds can be vaccinated during an outbreak without triggering trade bans or border restrictions from international trade partners.
Enhancing Smallholder and Pastoralist Livelihoods
-
Livestock Disease Resilience: Identifying key genetic markers and adaptive traits in indigenous livestock species has enabled the development of breeding and management frameworks that withstand viral challenges, extreme heat, and climate-induced stressors.
-
Sustainable Protein Security: Characterising resilient and emerging domesticate species provides rural communities with viable, climate-adapted alternatives to traditional livestock, diversifying income and strengthening food systems against climate volatility.
Informing One Health Surveillance and Policy
-
Real-Time Pathogen Tracking: Applying long-read genomic sequencing and molecular phylodynamics to vector-borne and zoonotic pathogens enables health authorities to trace transmission pathways at wildlife–livestock–human interfaces, improving biosecurity early-warning systems.
-
Evidence-Based Biosecurity Guidelines: Research findings from viral surveillance across multi-species ecosystems have directly informed regional biosecurity protocols and disease containment strategies.
Capacity Building and Workforce Leadership
-
Mentoring Next-Generation Scientists: Having supervised more than 20 PhD and MSc researchers to successful completion, A/Prof Ommeh has actively built computational biology, genomics, and diagnostic pipeline capacity across global research hubs, equipping the agricultural and public health sectors with highly skilled biosecurity leaders.
-
She is continuously engaged in mentoringearly career researchers, equipping emerging scientists with the strategic and leadership skills required to drive the future of the agricultural biotechnology, and public health sectors.
Works
Search Professor Sheila Ommeh’s works on UQ eSpace
2020
Journal Article
Potential dual expansion of domesticated donkeys revealed by worldwide analysis on mitochondrial sequences
Ma, Xi-Yao, Ning, Tiao, Adeola, Adeniyi C., Li, Jie, Esmailizadeh, Ali, Lichoti, Jacqueline K., Agwanda, Bernard R., Isakova, Jainagul, Aldashev, Almaz A., Wu, Shi-Fang, Liu, He-Qun, Abdulloevich, Najmudinov Tojiddin, Afanasevna, Manilova Elena, Ibrohimovich, Khudoidodov Behruz, Adedokun, Rahamon Akinyele Moshood, Olaogun, Sunday Charles, Sanke, Oscar J., Mangbon, Godwin F., Chen, Xi, Yang, Wei-Kang, Wang, Zhe, Peng, Min-Sheng, Ommeh, Sheila C., Li, Yan and Zhang, Ya-Ping (2020). Potential dual expansion of domesticated donkeys revealed by worldwide analysis on mitochondrial sequences. Zoological Research, 41 (1), 51-60. doi: 10.24272/j.issn.2095-8137.2020.007
2019
Journal Article
Molecular detection and genetic characterization of Novel RNA viruses in wild and synanthropic rodents and shrews in Kenya
Onyuok, Samson Omondi, Hu, Ben, Li, Bei, Fan, Yi, Kering, Kelvin, Ochola, Griphin Ochieng, Zheng, Xiao-Shuang, Obanda, Vincent, Ommeh, Sheila, Yang, Xing-Lou, Agwanda, Bernard and Shi, Zheng-Li (2019). Molecular detection and genetic characterization of Novel RNA viruses in wild and synanthropic rodents and shrews in Kenya. Frontiers in Microbiology, 10 2696, 1-11. doi: 10.3389/fmicb.2019.02696
2019
Journal Article
Serological evidence of MERS-CoV and HKU8-related CoV co-infection in Kenyan camels
Zhang, Wei, Zheng, Xiao-Shuang, Agwanda, Bernard, Ommeh, Sheila, Zhao, Kai, Lichoti, Jacqueline, Wang, Ning, Chen, Jing, Li, Bei, Yang, Xing-Lou, Mani, Shailendra, Ngeiywa, Kisa-Juma, Zhu, Yan, Hu, Ben, Onyuok, Samson Omondi, Yan, Bing, Anderson, Danielle E, Wang, Lin-Fa, Zhou, Peng and Shi, Zheng-Li (2019). Serological evidence of MERS-CoV and HKU8-related CoV co-infection in Kenyan camels. Emerging Microbes and Infections, 8 (1), 1528-1534. doi: 10.1080/22221751.2019.1679610
2019
Journal Article
Phenotypic and morphometric differentiation of indigenous chickens from Kenya and other tropical countries augments perspectives for genetic resource improvement and conservation
Otecko, Newton O., Ogali, Irene, Ng'ang'a, Said I., Mauki, David H., Ogada, Stephen, Moraa, Grace K., Lichoti, Jacqueline, Agwanda, Bernard, Peng, Min-Shen, Ommeh, Sheila C. and Zhang, Ya-Ping (2019). Phenotypic and morphometric differentiation of indigenous chickens from Kenya and other tropical countries augments perspectives for genetic resource improvement and conservation. Poultry Science, 98 (7), 2747-2755. doi: 10.3382/ps/pez097
2019
Journal Article
Canine transmissible venereal tumor genome reveals ancient introgression from coyotes to pre-contact dogs in North America
Wang, Xuan, Zhou, Bo-Wen, Yang, Melinda A., Yin, Ting-Ting, Chen, Fang-Liang, Ommeh, Sheila C., Esmailizadeh, Ali, Turner, Melissa M., Poyarkov, Andrei D., Savolainen, Peter, Wang, Guo-Dong, Fu, Qiaomei and Zhang, Ya-Ping (2019). Canine transmissible venereal tumor genome reveals ancient introgression from coyotes to pre-contact dogs in North America. Cell Research, 29 (7), 592-595. doi: 10.1038/s41422-019-0183-2
2019
Journal Article
Correction to: genetic evidence of Middle East Respiratory Syndrome Coronavirus (MERS-Cov) and widespread seroprevalence among camels in Kenya
Ommeh, Sheila, Zhang, Wei, Zohaib, Ali, Chen, Jing, Zhang, Huajun, Hu, Ben, Ge, Xing-Yi, Yang, Xing-Lou, Masika, Moses, Obanda, Vincent, Luo, Yun, Li, Shan, Waruhiu, Cecilia, Li, Bei, Zhu, Yan, Ouma, Desterio, Odendo, Vincent, Wang, Lin-Fa, Anderson, Danielle E, Lichoti, Jacqueline, Mungube, Erick, Gakuya, Francis, Zhou, Peng, Ngeiywa, Kisa-Juma, Yan, Bing, Agwanda, Bernard and Shi, Zheng-Li (2019). Correction to: genetic evidence of Middle East Respiratory Syndrome Coronavirus (MERS-Cov) and widespread seroprevalence among camels in Kenya. Virologica Sinica, 34 (1), 115-115. doi: 10.1007/s12250-019-00092-6
2018
Journal Article
Genetic evidence of Middle East Respiratory Syndrome Coronavirus (MERS-Cov) and widespread seroprevalence among camels in Kenya
Ommeh, Sheila, Zhang, Wei, Zohaib, Ali, Chen, Jing, Zhang, Huajun, Hu, Ben, Ge, Xing-Yi, Yang, Xing-Lou, Masika, Moses, Obanda, Vincent, Luo, Yun, Li, Shan, Waruhiu, Cecilia, Li, Bei, Zhu, Yan, Ouma, Desterio, Odendo, Vincent, Wang, Lin-Fa, Anderson, Danielle E, Lichoti, Jacqueline, Mungube, Erick, Gakuya, Francis, Zhou, Peng, Ngeiywa, Kisa-Juma, Yan, Bing, Agwanda, Bernard and Shi, Zheng-Li (2018). Genetic evidence of Middle East Respiratory Syndrome Coronavirus (MERS-Cov) and widespread seroprevalence among camels in Kenya. Virologica Sinica, 33 (6), 484-492. doi: 10.1007/s12250-018-0076-4
2018
Journal Article
Mitochondrial DNA D-Loop Diversity of the Helmeted Guinea Fowls in Kenya and Its Implications on HSP70 Gene Functional Polymorphism
Murunga, Philip, Kennedy, Grace Moraa, Imboma, Titus, Malaki, Phillista, Kariuki, Daniel, Ndiema, Emmanuel, Obanda, Vincent, Agwanda, Bernard, Lichoti, Jacqueline Kasiiti and Ommeh, Sheila Cecily (2018). Mitochondrial DNA D-Loop Diversity of the Helmeted Guinea Fowls in Kenya and Its Implications on HSP70 Gene Functional Polymorphism. BioMed Research International, 2018 7314038, 1-12. doi: 10.1155/2018/7314038
2018
Journal Article
Molecular Characterization of Newcastle Disease Virus from Backyard Poultry Farms and Live Bird Markets in Kenya
Ogali, Irene N., Wamuyu, Lucy W., Lichoti, Jacqueline K., Mungube, Erick O., Agwanda, Bernard and Ommeh, Sheila C. (2018). Molecular Characterization of Newcastle Disease Virus from Backyard Poultry Farms and Live Bird Markets in Kenya. International Journal of Microbiology, 2018 2368597, 1-11. doi: 10.1155/2018/2368597
2018
Journal Article
Correction to: Molecular detection of viruses in Kenyan bats and discovery of novel astroviruses, caliciviruses and rotaviruses
Waruhiu, Cecilia, Ommeh, Sheila, Obanda, Vincent, Agwanda, Bernard, Gakuya, Francis, Ge, Xing-Yi, Yang, Xing-Lou, Wu, Li-Jun, Zohaib, Ali, Hu, Ben and Shi, Zheng-Li (2018). Correction to: Molecular detection of viruses in Kenyan bats and discovery of novel astroviruses, caliciviruses and rotaviruses. Virologica Sinica, 33 (3), 294-294. doi: 10.1007/s12250-018-0035-0
2017
Journal Article
Molecular detection of viruses in Kenyan bats and discovery of novel astroviruses, caliciviruses and rotaviruses
Waruhiu, Cecilia, Ommeh, Sheila, Obanda, Vincent, Agwanda, Bernard, Gakuya, Francis, Ge, Xing-Yi, Yang, Xing-Lou, Wu, Li-Jun, Zohaib, Ali, Hu, Ben and Shi, Zheng-Li (2017). Molecular detection of viruses in Kenyan bats and discovery of novel astroviruses, caliciviruses and rotaviruses. Virologica Sinica, 32 (2), 101-114. doi: 10.1007/s12250-016-3930-2
2017
Journal Article
A cryptic mitochondrial DNA link between North European and West African dogs
Adeola, Adeniyi C., Ommeh, Sheila C., Song, Jiao-Jiao, Olaogun, S. Charles, Sanke, Oscar J., Yin, Ting-Ting, Wang, Guo-Dong, Wu, Shi-Fang, Zhou, Zhong-Yin, Lichoti, Jacqueline K., Agwanda, Bernard R., Dawuda, Philip M., Murphy, Robert W., Peng, Min-Sheng and Zhang, Ya-Ping (2017). A cryptic mitochondrial DNA link between North European and West African dogs. Journal of Genetics and Genomics, 44 (3), 163-170. doi: 10.1016/j.jgg.2016.10.008
2016
Journal Article
A survey on disease prevalence, ectoparasite infestation and chick mortality in poultry populations of Kenya
Ogada, S., Lichoti, J., Oyier, P. A., Imboma, T., Peng, M. S., Ngeiywa, K. J. and Ommeh, S. C. (2016). A survey on disease prevalence, ectoparasite infestation and chick mortality in poultry populations of Kenya. Livestock Research for Rural Development: the international journal for research into sustainable developing world agriculture, 28 (12) 230.
2015
Journal Article
Mitochondrial DNA variation of Nigerian domestic helmeted guinea fowl
Adeola, Adeniyi C., Ommeh, Sheila C., Murphy, Robert W., Wu, Shi‐Fang, Peng, Min‐Sheng and Zhang, Ya‐Ping (2015). Mitochondrial DNA variation of Nigerian domestic helmeted guinea fowl. Animal Genetics, 46 (5), 576-579. doi: 10.1111/age.12324
2015
Journal Article
Molecular Detection and Characterization of Theileria Infecting Wildebeest (Connochaetes taurinus) in the Maasai Mara National Reserve, Kenya
Wamuyu, Lucy, Obanda, Vincent, Kariuki, Daniel, Gakuya, Francis, Makanda, Moni, Otiende, Moses and Ommeh, Sheila (2015). Molecular Detection and Characterization of Theileria Infecting Wildebeest (Connochaetes taurinus) in the Maasai Mara National Reserve, Kenya. Pathogens, 4 (3), 626-638. doi: 10.3390/pathogens4030626
2015
Journal Article
Downregulation of transcription factor aflR in Aspergillus flavus confers reduction to aflatoxin accumulation in transgenic maize with alteration of host plant architecture
Masanga, Joel Okoyo, Matheka, Jonathan Mutie, Omer, Rasha Adam, Ommeh, Sheila Cecily, Monda, Ethel Oranga and Alakonya, Amos Emitati (2015). Downregulation of transcription factor aflR in Aspergillus flavus confers reduction to aflatoxin accumulation in transgenic maize with alteration of host plant architecture. Plant Cell Reports, 34 (8), 1379-1387. doi: 10.1007/s00299-015-1794-9
2015
Journal Article
Third Report on Chicken Genes and Chromosomes 2015:
Schmid, Michael, Smith, Jacqueline, Burt, David W., Aken, Bronwen L., Antin, Parker B., Archibald, Alan L., Ashwell, Chris, Blackshear, Perry J., Boschiero, Clarissa, Brown, C. Titus, Burgess, Shane C., Cheng, Hans H., Chow, William, Coble, Derrick J., Cooksey, Amanda, Crooijmans, Richard P. M. A., Damas, Joana, Davis, Richard V.N., De Koning, Dirk-Jan, Delany, Mary E., Derrien, Thomas, Desta, Takele T., Dunn, Ian C., Dunn, Matthew, Ellegren, Hans, Eöry, Lél, Erb, Ionas, Farré, Marta, Fasold, Mario ... Zhou, Huaijun (2015). Third Report on Chicken Genes and Chromosomes 2015:. Cytogenetic and Genome Research, 145 (2), 78-179. doi: 10.1159/000430927
2014
Journal Article
Genome sequence of the tsetse fly (Glossina morsitans): vector of African trypanosomiasis
International Glossina Genome Initiative and Ommeh, Sheila (2014). Genome sequence of the tsetse fly (Glossina morsitans): vector of African trypanosomiasis. Science, 344 (6182), 380-386. doi: 10.1126/science.1249656
2012
Book Chapter
Genomics and Potential Downstream Applications in the Developing World
Djikeng, Appolinaire, Ommeh, Sheila, Sangura, Sitati, Njaci, Isaac and Ngara, Mtakai (2012). Genomics and Potential Downstream Applications in the Developing World. Advances in Microbial Ecology. (pp. 335-356) New York, NY United States: Springer. doi: 10.1007/978-1-4614-2182-5_20
2011
Journal Article
Basic molecular evolution workshop - a trans-African virtual training course
Ommeh, Sheila, Budd, Aidan, Ngara, Mtakai Vald, Njaci, Isaac and de Villiers, Etienne P. (2011). Basic molecular evolution workshop - a trans-African virtual training course. Bioessays, 33 (4), 243-247. doi: 10.1002/bies.201000139
Funding
Past funding
Supervision
Availability
- Associate Professor Sheila Ommeh is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Media
Enquiries
For media enquiries about Associate Professor Sheila Ommeh's areas of expertise, story ideas and help finding experts, contact our Media team: