
Overview
Background
Louise Conwell, MBBS(HonsI) PGCert MEd (Dundee) FRACP PhD, is a Senior Staff Specialist (Eminent) in Paediatric Endocrinology and Diabetes at the Queensland Children’s Hospital, Children’s Health Queensland. Louise’s work as a Paediatric Endocrinologist involves working in a multi-disciplinary team to care for neonates, children and adolescents with a wide spectrum of endocrinologist disorders.
Louise commenced as Head of the Children's Health Queensland Clinical Unit, School of Clinical Medicine, University of Queensland in June 2018. She is also the Acting Head of the Mayne Academy of Paediatrics, Faculty of Medicine, University of Queensland.
Louise is a graduate of the University of Queensland and trained in paediatrics at the Mater Children’s Hospital, Brisbane. She then trained in paediatric endocrinology and diabetes at the Royal Children’s Hospital in Brisbane while completing a PhD at the University of Queensland. Louise undertook a post-specialty Clinical Fellowship at the Division of Endocrinology and Metabolism, The Hospital for Sick Children, Uinversity of Toronto, Ontario, Canada.
Louise has a particular interest in Congenital Hyperinsulinism and other beta-cell disorders including Type 1 and Monogenic Diabetes. Her other clinical interest areas include Disorders of Sexual Differentiation and endocrine oncology. Louise currently works in the endocrine oncology clinic connected with the After Cancer Therapy Service at the Queensland Children's Hospital, Brisbane.
Louise's PhD was in the field of insulin resistance and cardiovascular risk in obese children and adolescents. Louise remains active in clinical research with grant attainment, particularly in the field of beta-cell disorders.
Louise is a member of national and international professional bodies. She is the current President (past Secretary) of the Australasian Paediatric Endocrine Group, serving on Council since November 2017. She also has past or present committee memberships including the Scientific Organising Committee, Clinical Fellows School Committee, Diabetes Committee, the Disorders of Sexual Differentiation Committee, Registry Committee, Research Grant Committee, Thyroid Working Group and the Cancer Survivorship Working Group).
Louise also has engagement with stakeholder groups, particularly Congenital Hyperinsulinism International. She is co-chair of the Congenital Hyperinsulinism International Collaborative Research Network - Care Guidelines and Centres of Excellence.
Louise represents the Australasian Paediatric Endocrine Group on the International Consortium of Pediatric Endocrinology (ICPE) and is co-chair of ICPE's subcommittee, the Intersociety Clinical Guidelines Committee (ICGC).
Louise has an interest in Evidence-Based Medicine, with authorship in the Cochrane Database of Systematic Reviews. She is co-Chair of the International Clinical Guidelines Committee of the International Consortium of Paediatric Endocrinology.
A further interest area includes medical ecucation, completing a Postgraduate Certificate in Medical Education (University of Dundee, Scotland) in 2017. She has facilitated and contributed to a wide range of educational activities for a variety of student, professional and community stakeholder groups in a range of contexts. Louise is a supervisor of basic and advanced paediatric trainees of the Royal Australasian College of Physicians. Other roles include Supervisor, Reader and Examiner for Postgraduate Higher Degree Research students of the University of Queensland and other academic institutions in Australia.
Availability
- Associate Professor Louise Conwell is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
- Doctor of Philosophy, The University of Queensland
- Royal Australasian College of Physicians, Royal Australasian College of Physicians
Research interests
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Congenital hyperinsulinism
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Evidence Based Medicine
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Obesity, Cardiovascular Risk and Insulin Resistance in Children and Adolescents
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Type 1 Diabetes Mellitus
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Other beta cells disorders - Monogenic Diabetes (MODY) and genetics
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Disorders of Sexual Development
Works
Search Professor Louise Conwell’s works on UQ eSpace
2019
Conference Publication
Hyperinsulinaemic Hypoglycaemia: A New Presentation of 16p11.2 Duplication Syndrome
Conwell, Louise and Flanagan, Sarah (2019). Hyperinsulinaemic Hypoglycaemia: A New Presentation of 16p11.2 Duplication Syndrome. 58th Annual Meeting of the European Society for Paediatric Endocrinology (ESPE), Vienna, Austria, September 2019. Basel, Switzerland: Karger.
2019
Conference Publication
Neonatal Secondary Hyperparathyroidism: a clue to mucolipidosis type II
Papadimos, E.R., Coman, D., Conwell, L.S., McGill, J., Demetriou, K., Inwood, A. and Harris, M. (2019). Neonatal Secondary Hyperparathyroidism: a clue to mucolipidosis type II. Australasian Paediatric Endocrine Group Annual Scientific Meeting, Adelaide, SA, Australia, 27-30 October 2019.
2019
Journal Article
Cost-effectiveness analysis of routine screening using massively parallel sequencing for maturity-onset diabetes of the young in a pediatric diabetes cohort: reduced health system costs and improved patient quality of life
Johnson, Stephanie R., Carter, Hannah E., Leo, Paul, Hollingworth, Samantha A., Davis, Elizabeth A., Jones, Timothy W., Conwell, Louise S., Harris, Mark, Brown, Matthew A., Graves, Nicholas and Duncan, Emma L. (2019). Cost-effectiveness analysis of routine screening using massively parallel sequencing for maturity-onset diabetes of the young in a pediatric diabetes cohort: reduced health system costs and improved patient quality of life. Diabetes Care, 42 (1), 69-76. doi: 10.2337/dc18-0261
2019
Conference Publication
Hyperinsulinaemic Hypoglycaemia: A new Presentation of 16p11.2 Duplication Syndrome
Conwell, Louise S. and Flanagan, Sarah F. (2019). Hyperinsulinaemic Hypoglycaemia: A new Presentation of 16p11.2 Duplication Syndrome. Updates in Diagnosis and Management of Hyperinsulinism and Neonatal Hypoglycemia Conference, Philadelphia, PA, United States, 5-6 September 2019.
2018
Journal Article
Predicted benign and synonymous variants in CYP11A1 causes primary adrenal insufficiency through missplicing
Maharaj, Avinaash, Buonocore, Federica, Meimaridou, Eirini, Ruiz-Babot, Gerard, Guasti, Leonardo, Peng, Hwei-Ming, Capper, Cameron P., Burgos-Tirado, Neikelyn, Prasad, Rathi, Hughes, Claire R., Maudhoo, Ashwini, Crowne, Elizabeth, Cheetham, Timothy D., Brain, Caroline E., Suntharalingham, Jenifer P., Striglioni, Niccolò, Yuksel, Bilgin, Gurbuz, Fatih, Gupta, Sangay, Lindsay, Robert, Couch, Robert, Spoudeas, Helen A., Guran, Tulay, Johnson, Stephanie, Fowler, Dallas J, Conwell, Louise S., McInerney-Leo, Aideen M., Drui, Delphine, Cariou, Bertrand ... Metherell, Louise A. (2018). Predicted benign and synonymous variants in CYP11A1 causes primary adrenal insufficiency through missplicing. Journal of the Endocrine Society, 3 (1), 201-221. doi: 10.1210/js.2018-00130
2018
Journal Article
Clinical usefulness of comprehensive genetic screening in maturity onset diabetes of the young (MODY): a novel ABCC8 mutation in a previously screened family
Johnson, Stephanie R., Leo, Paul, Conwell, Louise S., Harris, Mark, Brown, Matthew A. and Duncan, Emma L. (2018). Clinical usefulness of comprehensive genetic screening in maturity onset diabetes of the young (MODY): a novel ABCC8 mutation in a previously screened family. Journal of Diabetes, 10 (9), 764-767. doi: 10.1111/1753-0407.12778
2018
Journal Article
A novel INS mutation in a family with maturity-onset diabetes of the young: variable insulin secretion and putative mechanisms
Johnson, Stephanie R., Mcgown, Ivan, Oppermann, Udo, Conwell, Louise S., Harris, Mark and Duncan, Emma L. (2018). A novel INS mutation in a family with maturity-onset diabetes of the young: variable insulin secretion and putative mechanisms. Pediatric Diabetes, 19 (5), 905-909. doi: 10.1111/pedi.12679
2018
Conference Publication
Congenital hyperinsulinism due to pancreatic mosaicism for paternal uniparental disomy of all chromosome 11, with the additional finding of pancreatic mosaicism for trisomy 12
Conwell, Louise S., Harroway, James, Williams, Mark, Joy, Christopher, Scurry, Bonnie, Lee, Kevin, McBride, Craig, Choo, Kelvin, Huynh, Tony and Ng, Carolyn G. L. (2018). Congenital hyperinsulinism due to pancreatic mosaicism for paternal uniparental disomy of all chromosome 11, with the additional finding of pancreatic mosaicism for trisomy 12. Australasian Paediatric Endocrine Group Annual Scientific Meetings, Newcastle, Australia, July 2018.
2018
Conference Publication
Autonomous thyroid nodule – not just a disease of adulthood
Papadimos, E., Perry, E., Goodwin, B. and Conwell, L. S. (2018). Autonomous thyroid nodule – not just a disease of adulthood. Australasian Paediatric Endocrine Group Annual Scientific Meeting, Newcastle, NSW Australia, July 2018.
2018
Conference Publication
Molecular and functional studies in a case of Familial Congenital Hyperinsulinism: co-inheritance of a dominant and recessive ABCC8 mutation
Conwell, Louise S., Shyng, Show-Ling, Kandasamy, Balamurugan, Wu, Yi and McGown, Ivan (2018). Molecular and functional studies in a case of Familial Congenital Hyperinsulinism: co-inheritance of a dominant and recessive ABCC8 mutation. Australian Functional Genomics Conference, Melbourne, Australia, September 2018.
2017
Conference Publication
Early complications of first presentation diabetic ketoacidosis are predicted by severity
Sharwood, Erin F. and Conwell, Louise S. (2017). Early complications of first presentation diabetic ketoacidosis are predicted by severity. Australasian Paediatric Endocrine Group Annual Scientific Meeting, Hobart , Tasmania, Australia, 26-29 November 2017.
2017
Conference Publication
Idiopathic Ductopaenia in a Paediatric Patient: A Case Report and Interesting Clinical Biochemistry
Ruddell, Richard G., Burgess, Christopher, Huynh, Tony, Conwell, Louise S., Balouch, Fariha, Burke, Matthew and Pretorius, Carel (2017). Idiopathic Ductopaenia in a Paediatric Patient: A Case Report and Interesting Clinical Biochemistry. Royal College of Pathology Australia Update, Sydney, NSW, Australia, 24 – 26 February 2017.
2017
Conference Publication
46,XX Ovotesticular Disorder of Sex Development (DSD):- duplication of the XX SR region upstream of the critical testicular gene SOX9
Conwell, Louise S. , Stathis, Stephen , Franklin, Annie , Borzi, Peter A., Nandini, Adayapalam , Phillips, Gayle E., Ohnesorg, Thomas , Ayers, Katie L. and Sinclair, Andrew H. (2017). 46,XX Ovotesticular Disorder of Sex Development (DSD):- duplication of the XX SR region upstream of the critical testicular gene SOX9. International Disorders of Sexual Development Conference, Copenhagen, Denmark, 29 June-1 July 2017. Copenhagen, Denmark: I-DSD.
2017
Conference Publication
Turner Syndrome with Ring X Karyotype: Two Cases with Features of the Metabolic Syndrome.
Papadimos, Emily R. and Conwell, Louise S. (2017). Turner Syndrome with Ring X Karyotype: Two Cases with Features of the Metabolic Syndrome.. Australasian Paediatric Endocrine Group Annual Scientific Meeting, Hobart , Tasmania, Australia, 26-29 November 2017.
2017
Conference Publication
Antenatally determined sesquizygosity in gender discordant monochorionic diammniotic twins (46,XX/46XY):- postnatal clinical and gonadal phenotype
Conwell, Louise S., Phillips, Gayle E., Nandini, Adayapalam, Borzi, Peter A. and Gabbett, Michael T. (2017). Antenatally determined sesquizygosity in gender discordant monochorionic diammniotic twins (46,XX/46XY):- postnatal clinical and gonadal phenotype. 3rd Annual Children's Health Queensland Research Symposium, Brisbane, Queensland, Australia, 1 November 2017.
2017
Conference Publication
46,XX Ovotesticular Disorder of Sex Development (DSD): duplication of the XX SR region upstream of the critical testicular gene SOX9.
Conwell, Louise S. , Stathis, Stephen , Franklin, Annie , Borzi, Peter A. , Nandini, Adayapalam , Phillips, Gayle E. , Ohnesorg, Thomas , Ayers, Katie L. and Sinclair, Andrew H. (2017). 46,XX Ovotesticular Disorder of Sex Development (DSD): duplication of the XX SR region upstream of the critical testicular gene SOX9.. 10th International Meeting of Pediatric Endocrinology, Washington, United States, 14-17 September 2017.
2017
Conference Publication
Co-inheritance of Dominant and Recessive ABCC8 Mutations in a Case of Familial Congenital Hyperinsulinism:- Molecular and Functional Studies
Conwell, Louise S. , Shyng, Show-Ling , Kandasamy, Balamurugan , Wu, Yi , McGown, Ivan , Choo, Kelvin and McBride, Craig (2017). Co-inheritance of Dominant and Recessive ABCC8 Mutations in a Case of Familial Congenital Hyperinsulinism:- Molecular and Functional Studies. Australasian Paediatric Endocrine Group Annual Scientific Meeting, Hobart, Tasmania, Australia, 26-29 November 2017.
2017
Conference Publication
Co-inheritance of dominant and recessive ABCC8 mutations in a case of familial congenital hyperinsulinism (CHI):- molecular and functional studies
Conwell, Louise S., Shyng, Show-Ling, Kandasamy, Balamurugan, Wu, Yi, Mcgown, Ivan, Choo, Kelvin L. and Mcbride, Craig A. (2017). Co-inheritance of dominant and recessive ABCC8 mutations in a case of familial congenital hyperinsulinism (CHI):- molecular and functional studies. 10th International Meeting of Pediatric Endocrinology, Washington, DC, United States, 14 - 17 September 2017. Basel, Switzerland: S. Karger AG.
2017
Conference Publication
Co-inheritance of dominant and recessive ABCC8 mutations in a case of familial Congenital Hyperinsulinism (CHI):- molecular and functional studies
Conwell, Louise S., Shyng, Show-Ling , Kandasamy, Balamurugan , Wu, Yi , McGown, Ivan , Choo, Kelvin and McBride, Craig (2017). Co-inheritance of dominant and recessive ABCC8 mutations in a case of familial Congenital Hyperinsulinism (CHI):- molecular and functional studies. 10th International Meeting of Pediatric Endocrinology, Washington, DC, United States, 14-17 September 2017.
2017
Conference Publication
Co-inheritance of dominant and recessive ABCC8 mutations in a case of familial congenital hyperinsulinism:- molecular and functional studies
Conwell, Louise S., Shyng, Show-Ling, Kandasamy, Balamurugan, Wu, Yi, McGown, Ivan, Choo, Kelvin and McBride, Craig (2017). Co-inheritance of dominant and recessive ABCC8 mutations in a case of familial congenital hyperinsulinism:- molecular and functional studies. 3rd Annual Children's Health Queensland Research Symposium, Brisbane, Queensland, Australia, 1 November 2017.
Supervision
Availability
- Associate Professor Louise Conwell is:
- Available for supervision
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Supervision history
Completed supervision
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2018
Doctor Philosophy
Monogenic Disorders of Glucose-Stimulated Insulin Secretion: Massively Parallel Sequencing Approaches
Associate Advisor
Media
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