Kesh Baboolal

Renal Research

Professor Keshwar was awarded a National Kidney Research Fellowship and Juvenile Diabetes Foundation International Research Fellowship in the Division of Nephrology at Stanford University, California from 1992-1995. He studied the role of the renin angiotensin system in models of progressive renal disease. I have led a research group of post doctorate scientists, clinician trainees and MD candidates that has explored the role of the renin angiotensin system in human renal disease.

Within transplantation Professor Baboolal has studied and explored the molecular determinants of renal allograft nephropathy as well as explored the pathophysiology of new onset diabetes after transplantation. This work has included laboratory based basic science research, clinical research involving complex physiology measurements in humans and clinical trials. With regards to clinical trials he has been both a principal investigator and supported multicentre international investigations. The work has been funded through a number of peer reviewed competive research grants. The outputs of this work have been published in International peer reviewed journals, presented at International Meetings as both invited speakers and as abstracts.

Health Economics

More recently Professor Baboolal has developed a research interest in healthcare economics related to renal disease and transplantation.

As a consequence of this work he has been asked to provide expert advice to N.I.C.E. (National Institute of Clinical Excellence) and the Department of Health UK to help set the National Tariff for renal replacement therapy in the UK.

Operational Research.

Professor Baboolal created an Operational Research Unit in collaboration with the School of Mathematics at Cardiff University. The work used operational sciences including modelling and forecasting to help optimise the design of clinical services and systems, particulary in Emergency Departments

Ethical and Regulatory Guidelines Related to Transplantation

Professor Baboolal has also been involved in developing clinical, ethical and regulatory guidelines for many aspects of transplantation.

• Advisor to the Human Tissue Authority: I have provided professional advice to the Authority on the implementation of the Human Tissue Act and provided clinical advice on the interpretation of the Act in complex clinical cases referred to the Authority.
• Appointed Member of the Department of Health Advisory Board for the Safety of Blood Tissues and Organs. This National Policy Advice Group is charged with developing advice to Parliament to ensure the safe supply of tissues for medical use and research.
• Appointed member to the UK Academy of Royal Colleges Ethics Committee. This committee provides ethical guidance on issues related to organ donation and transplantation.
• Co-author of Ethical Guidance for Deceased Cardiac Death Donation. UK Academy of Royal Colleges Ethics Committee
• Member of the British Transplant Society Ethics Committee 2004-2006
• Co-author of British Transplant Society Guidelines with regards to consent for organ donation.
• Advice to the Scottish Parliament on the new legal framework for organ donation in the UK.