Overview
Availability
- Dr Mercedes Monteleone is:
- Available for supervision
Qualifications
- Doctor of Philosophy, University of Sydney
Works
Search Professor Mercedes Monteleone’s works on UQ eSpace
2024
Journal Article
Pyroptotic cell corpses are crowned with F-actin-rich filopodia that engage CLEC9A signaling in incoming dendritic cells
Holley, Caroline L., Monteleone, Mercedes, Fisch, Daniel, Libert, Alexandre E. S., Ju, Robert J., Choi, Joon H., Condon, Nicholas D., Emming, Stefan, Crawford, Joanna, Lawrence, Grace M. E. P., Coombs, Jared R., Lefevre, James G., Bajracharya, Rinie, Lahoud, Mireille H., Yap, Alpha S., Hamilton, Nicholas, Stehbens, Samantha J., Kagan, Jonathan C., Ariotti, Nicholas, Burgener, Sabrina S. and Schroder, Kate (2024). Pyroptotic cell corpses are crowned with F-actin-rich filopodia that engage CLEC9A signaling in incoming dendritic cells. Nature Immunology, 26 (1) eaas8995, 1-35. doi: 10.1038/s41590-024-02024-3
2024
Journal Article
The septin modifier, forchlorfenuron, activates NLRP3 via a potassium-independent mitochondrial axis
Holley, Caroline L., Emming, Stefan, Monteleone, Mercedes M., Mellacheruvu, Manasa, Kenney, Kirsten M., Lawrence, Grace M.E.P., Coombs, Jared R., Burgener, Sabrina S. and Schroder, Kate (2024). The septin modifier, forchlorfenuron, activates NLRP3 via a potassium-independent mitochondrial axis. Cell Chemical Biology, 31 (5), 962-972.e4. doi: 10.1016/j.chembiol.2024.04.012
2024
Journal Article
Fluorochrome‐labeled inhibitors of caspase‐1 require membrane permeabilization to efficiently access caspase‐1 in macrophages
Thygesen, Sara J., Burgener, Sabrina S., Mudai, Prerna, Monteleone, Mercedes, Boucher, Dave, Sagulenko, Vitaliya, Schroder, Kate and Stacey, Katryn J. (2024). Fluorochrome‐labeled inhibitors of caspase‐1 require membrane permeabilization to efficiently access caspase‐1 in macrophages. European Journal of Immunology, 54 (5) 2350515, e2350515. doi: 10.1002/eji.202350515
2024
Journal Article
Pyroptotic corpses are flagged by filopodia to alert dendritic cells
Monteleone, Mercedes and Schroder, Kate (2024). Pyroptotic corpses are flagged by filopodia to alert dendritic cells. Nature Immunology, 26 (1), 11-12. doi: 10.1038/s41590-024-02025-2
2023
Book Chapter
Quantifying Cell Death Induced by the NLRC4 Inflammasome
Emming, Stefan, Monteleone, Mercedes M., Kambara, Hiroto, Starchenko, Alina, Alley, Jennifer, Nolan, Michael A., Li, Wei, Kilty, Iain and Schroder, Kate (2023). Quantifying Cell Death Induced by the NLRC4 Inflammasome. NLR Proteins: Methods and Protocols. (pp. 199-210) New York, NY United States: Humana Press. doi: 10.1007/978-1-0716-3350-2_13
2022
Book Chapter
Measuring non-canonical inflammasome activation in neutrophils
Monteleone, Mercedes and Boucher, Dave (2022). Measuring non-canonical inflammasome activation in neutrophils. The inflammasome: methods and protocols. (pp. 29-37) edited by Ali A. Abdul-Sater. New York, NY, United States: Humana Press. doi: 10.1007/978-1-0716-2144-8_3
2021
Journal Article
Streptolysins are the primary inflammasome activators in macrophages during Streptococcus pyogenes infection
Richter, Johanna, Monteleone, Mercedes M, Cork, Amanda J., Barnett, Timothy C., Nizet, Victor, Brouwer, Stephan, Schroder, Kate and Walker, Mark J. (2021). Streptolysins are the primary inflammasome activators in macrophages during Streptococcus pyogenes infection. Immunology and Cell Biology, 99 (10), 1-13. doi: 10.1111/imcb.12499
2021
Journal Article
Vincristine-induced peripheral neuropathy is driven by canonical NLRP3 activation and IL-1β release
Starobova, Hana, Monteleone, Mercedes, Adolphe, Christelle, Batoon, Lena, Sandrock, Cheyenne J., Tay, Bryan, Deuis, Jennifer R., Smith, Alexandra V., Mueller, Alexander, Nadar, Evelyn Israel, Lawrence, Grace Pamo, Mayor, Amanda, Tolson, Elissa, Levesque, Jean-Pierre, Pettit, Allison R., Wainwright, Brandon J., Schroder, Kate and Vetter, Irina (2021). Vincristine-induced peripheral neuropathy is driven by canonical NLRP3 activation and IL-1β release. Journal of Experimental Medicine, 218 (5) e20201452. doi: 10.1084/jem.20201452
2019
Journal Article
Mycobacterium tuberculosis requires glyoxylate shunt and reverse methylcitrate cycle for lactate and pyruvate metabolism
Serafini, Agnese, Tan, Lendl, Horswell, Stuart, Howell, Steven, Greenwood, Daniel J., Hunt, Deborah M., Phan, Minh-Duy, Schembri, Mark, Monteleone, Mercedes, Montague, Christine R., Britton, Warwick, Garza-Garcia, Acely, Snijders, Ambrosius P., VanderVen, Brian, Gutierrez, Maximiliano G., West, Nicholas P. and de Carvalho, Luiz Pedro S. (2019). Mycobacterium tuberculosis requires glyoxylate shunt and reverse methylcitrate cycle for lactate and pyruvate metabolism. Molecular Microbiology, 112 (4) mmi.14362, 1284-1307. doi: 10.1111/mmi.14362
2019
Journal Article
The Salmonella pathogenicity island-2 subverts human NLRP3 and NLRC4 inflammasome responses
Bierschenk, Damien, Monteleone, Mercedes, Moghaddas, Fiona, Baker, Paul J., Masters, Seth L., Boucher, Dave and Schroder, Kate (2019). The Salmonella pathogenicity island-2 subverts human NLRP3 and NLRC4 inflammasome responses. Journal of Leukocyte Biology, 105 (2), 401-410. doi: 10.1002/JLB.MA0318-112RR
2018
Journal Article
Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular traps
Chen, Kaiwen W., Monteleone, Mercedes, Boucher, Dave, Sollberger, Gabriel, Ramnath, Divya, Condon, Nicholas D., von Pein, Jessica B., Broz, Petr, Sweet, Matthew J. and Schroder, Kate (2018). Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular traps. Science Immunology, 3 (26) eaar6676, eaar6676. doi: 10.1126/sciimmunol.aar6676
2018
Journal Article
Interleukin-1β maturation triggers its relocation to the plasma membrane for gasdermin-D-dependent and -independent secretion
Monteleone, Mercedes, Stanley, Amanda C., Chen, Kaiwen W., Brown, Darren L., Bezbradica, Jelena S., von Pein, Jessica B., Holley, Caroline L., Boucher, Dave, Shakespear, Melanie R., Kapetanovic, Ronan, Rolfes, Verena, Sweet, Matthew J., Stow, Jennifer L. and Schroder, Kate (2018). Interleukin-1β maturation triggers its relocation to the plasma membrane for gasdermin-D-dependent and -independent secretion. Cell Reports, 24 (6), 1425-1433. doi: 10.1016/j.celrep.2018.07.027
2018
Journal Article
Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity
Boucher, Dave, Monteleone, Mercedes, Coll, Rebecca C., Chen, Kaiwen W., Ross, Connie M., Teo, Jessica L., Gomez, Guillermo A., Holley, Caroline L., Bierschenk, Damien, Stacey, Katryn J., Yap, Alpha S., Bezbradica, Jelena S. and Schroder, Kate (2018). Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity. The Journal of Experimental Medicine, 215 (3), 827-840. doi: 10.1084/jem.20172222
2016
Journal Article
Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages
Kapetanovic, Ronan, Bokil, Nilesh J., Achard, Maud E. S., Ong, Cheryl-lynn Y, Peters, Kate M., Stocks, Claudia J., Phan, Minh-Duy, Monteleone, Mercedes, Schroder, Kate, Irvine, Katharine M., Saunders, Bernadette M., Walker, Mark J., Stacey, Katryn J., McEwan, Alastair G., Schembri, Mark A. and Sweet, Matthew J. (2016). Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages. The FASEB Journal, 30 (5), 1901-1912. doi: 10.1096/fj.201500061
2015
Journal Article
NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5
Baker, Paul J., Boucher, Dave, Bierschenk, Damien, Tebartz, Christina, Whitney, Paul G., D'Silva, Damian B, Tanzer, Marco J., Monteleone, Mercedes, Robertson, Avril A.B., Cooper, Matthew A., Alvarez-Diaz, Silvia, Herold, Marco J., Bedoui, Sammy, Schroder, Kate and Masters, Seth L. (2015). NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5. European Journal of Immunology, 45 (10), 2918-2926. doi: 10.1002/eji.201545655
2015
Journal Article
Mechanisms of unconventional secretion of IL-1 family cytokines
Monteleone, Mercedes, Stow, Jennifer L. and Schroder, Kate (2015). Mechanisms of unconventional secretion of IL-1 family cytokines. Cytokine, 74 (2), 213-218. doi: 10.1016/j.cyto.2015.03.022
2014
Journal Article
Plasmin(ogen) acquisition by group A Streptococcus protects against C3b-mediated neutrophil killing
Ly, Diane, Taylor, Jude M., Tsatsaronis, James A., Monteleone, Mercedes M., Skora, Amanda S., Donald, Cortny A., Maddocks, Tracy, Nizet, Victor, West, Nicholas P., Ranson, Marie, Walker, Mark J., McArthur, Jason D. and Sanderson-Smith, Martina L. (2014). Plasmin(ogen) acquisition by group A Streptococcus protects against C3b-mediated neutrophil killing. Journal of Innate Immunity, 6 (2), 240-250. doi: 10.1159/000353754
2013
Journal Article
A genetic strategy to identify targets for the development of drugs that prevent bacterial persistence
Kim, Jee-Hyun, O'Brien, Kathryn M., Sharma, Ritu, Boshoff, Helena I. M., Rehren, German, Chakraborty, Sumit, Wallach, Joshua B., Monteleone, Mercedes, Wilson, Daniel J., Aldrich, Courtney C., Barry, Clifton E., III, Rhee, Kyu Y., Ehrt, Sabine and Schnappinger, Dirk (2013). A genetic strategy to identify targets for the development of drugs that prevent bacterial persistence. Proceedings of the National Academy of Sciences of the United States of America, 110 (47), 19095-19100. doi: 10.1073/pnas.1315860110
2007
Journal Article
In vivo gene silencing identifies the Mycobacterium tuberculosis proteasome as essential for the bacteria to persist in mice
Gandotra, Sheetal, Schnappinger, Dirk, Monteleone, Mercedes, Hillen, Wolfgang and Ehrt, Sabine (2007). In vivo gene silencing identifies the Mycobacterium tuberculosis proteasome as essential for the bacteria to persist in mice. Nature Medicine, 13 (12), 1515-1520. doi: 10.1038/nm1683
2007
Journal Article
Silencing essential protein secretion in Mycobacterium smegmatis by using tetracycline repressors
Guo, Xinzheng V., Monteleone, Mercedes, Klotzsche, Marcus, Kamionka, Annette, Hillen, Wolfgang, Braunstein, Miriam, Ehrt, Sabine and Schnappinger, Dirk (2007). Silencing essential protein secretion in Mycobacterium smegmatis by using tetracycline repressors. Journal of Bacteriology, 189 (13), 4614-4623. doi: 10.1128/JB.00216-07
Funding
Past funding
Supervision
Availability
- Dr Mercedes Monteleone is:
- Available for supervision
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