Engineered Polymer Nanoparticles: A Potent Weapon Against Cancer (2009-2011)
Abstract
The project aims to develop a potent anti-cancer drug delivery device through the use of engineered nanoparticles with site and cell targeting ability. By combining novel polymer architectures with a combination of siRNA, a chemotherapeutic drug and cancer cell targeting agents, delivery of the resultant self-assembled nanoparticle will target and kill cancerous cells found in selective tissues or organs. siRNA is a revolutionary means to silence gene expression, and has shown real promise in the treatment of cervical cancer. This research will also aid in the treatment of other cancers, infectious diseases and genetic disorders.
