How does the nutrient choline regulate blood vessel formation in the brain? (2025-2027)
Abstract
This project aims to understand how blood vessels in the brain are formed. There are more than 600 km of blood vessels in the brain that supply it with critical nutrients, but there is a significant knowledge gap surrounding how these blood vessels grow, and what regulates this growth. This research will use cutting edge experimental methods and an interdisciplinary approach to understand how the essential nutrient choline enters the cells that line blood vessels in the brain and regulates growth of these blood vessels. It is hoped that findings from this study will enhance our understanding of the brain's core infrastructure and reveal how cerebral blood vessels grow and maintain integrity.
