Capturing elusive bionanoparticles via oscillating field induced convection (2025 ARC Discovery Project administered by Charles Sturt University) (2025-2028)
Abstract
Capturing tiny bioparticles at low concentrations within biofluids poses a major challenge for broad bioanalysis applications. The project aims to develop a novel sample preparation method that enhances bioparticle capture and isolation processes. This method will prevent unwanted biomolecules from adhering to surfaces and enable selective target capture, thus improving detection specificity and sensitivity. This will be achieved using convective fluid motion, a recently discovered phenomenon triggered by an oscillating magnetic field. The outcomes will enable efficient isolation and detection of a wide range of biomolecules in biomedical, agricultural and environmental applications, resulting in significant economic benefits for Australia.