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2025

Conference Publication

Australian patients with IDH<sub>1 </sub>mutatedcholangiocarcinoma treated with ivosidenib: initial resultsfrom the phase 3b ProvIDHe study

Price, Tim, Sim, Hao-Wen, Eastgate, Melissa, Mclachlan, Sue-Anne, Dean, Andrew, George, David, Weeratunge, Roshi, Zhang, Yoz and Oo, Maung Maung (2025). Australian patients with IDH1 mutatedcholangiocarcinoma treated with ivosidenib: initial resultsfrom the phase 3b ProvIDHe study. HOBOKEN: WILEY.

Australian patients with IDH<sub>1 </sub>mutatedcholangiocarcinoma treated with ivosidenib: initial resultsfrom the phase 3b ProvIDHe study

2025

Conference Publication

Retrospective cohort study of Treatment Patterns and Outcomes for Patients with locally advanced Rectal Cancer across Three Metropolitan Hospitals in Brisbane

Macilwraith, Philip, Turner, Cassie, Roberts, Kate, Bigby, Kieron, Kang, Sebastian, Wyld, David, Burge, Matthew and Eastgate, Melissa (2025). Retrospective cohort study of Treatment Patterns and Outcomes for Patients with locally advanced Rectal Cancer across Three Metropolitan Hospitals in Brisbane. HOBOKEN: WILEY.

Retrospective cohort study of Treatment Patterns and Outcomes for Patients with locally advanced Rectal Cancer across Three Metropolitan Hospitals in Brisbane

2025

Conference Publication

Patterns of radiological progression in participants (pts) with embolization-eligible hepatocellular carcinoma (HCC) treated with durvalumab (D) plus bevacizumab (B) plus transarterial chemoembolization (TACE) and placebos plus TACE: EMERALD-1 post hoc analysis

Roderburg, C., Sangro, B., Bouattour, M., Park, J. -W., Romero, M. Del Consuelo Diaz, Erinjeri, J. P., Alves, G., Gu, S., Manikhas, A., Kuroda, H., Suksombooncharoen, T., Vo, T. Hoi Trung, Ostwal, V. S., Eastgate, M., Vaccaro, G., Griffin, R., Ali, S., Balaji, K. and Chan, S. L. (2025). Patterns of radiological progression in participants (pts) with embolization-eligible hepatocellular carcinoma (HCC) treated with durvalumab (D) plus bevacizumab (B) plus transarterial chemoembolization (TACE) and placebos plus TACE: EMERALD-1 post hoc analysis. BASEL: KARGER.

Patterns of radiological progression in participants (pts) with embolization-eligible hepatocellular carcinoma (HCC) treated with durvalumab (D) plus bevacizumab (B) plus transarterial chemoembolization (TACE) and placebos plus TACE: EMERALD-1 post hoc analysis

2025

Conference Publication

Patterns of radiological progression in participants (pts) with embolization-eligible hepatocellular carcinoma (HCC) treated with durvalumab (D)+bevacizumab (B)+transarterial chemoembolization (TACE) and placebos+TACE: EMERALD-1 post hoc analysis

Roderburg, C., Sangro, B., Bouattour, M., Park, J-W., del Consuelo Díaz Romero, M., Erinjeri, J. P., Alves, G., Gu, S., Manikhas, A., Kuroda, H., Suksombooncharoen, T., Hoi Trung Vo, T., Ostwal, V. S., Eastgate, M., Vaccaro, G., Griffin, R., Ali, S., Balaji, K. and Chan, S. L. (2025). Patterns of radiological progression in participants (pts) with embolization-eligible hepatocellular carcinoma (HCC) treated with durvalumab (D)+bevacizumab (B)+transarterial chemoembolization (TACE) and placebos+TACE: EMERALD-1 post hoc analysis. Annual conference of the German Society of Gastroenterology, and Digestive and Metabolic Diseases with Endoscopy Section (DGVS) Viszeralmedizin 2025, Leipzig, Germany, 15–20 September 2025. Stuttgart, Germany: Georg Thieme. doi: 10.1055/s-0045-1810980

Patterns of radiological progression in participants (pts) with embolization-eligible hepatocellular carcinoma (HCC) treated with durvalumab (D)+bevacizumab (B)+transarterial chemoembolization (TACE) and placebos+TACE: EMERALD-1 post hoc analysis

2025

Conference Publication

Patterns of radiological progression in participants (pts) with embolization-eligible hepatocellular carcinoma (HCC) treated with durvalumab (D) + bevacizumab (B) + transarterial chemoembolization (TACE) and placebos + TACE: EMERALD-1 post hoc analysis

Sangro, Bruno, Bouattour, Mohamed, Park, Joong-Won, Diaz, Dr. Consuelo, Erinjeri, Joseph P., Alves, Gustavo Vasconcelos, Gu, Shan-Zhi, Manikhas, Aleksei, Kuroda, Hidekatsu, Suksombooncharoen, Thatthan, Vo, Truc Hoi Trung, Ostwal, Vikas S., Eastgate, Melissa A., Vaccaro, Gina M., Griffin, Rebecca, Ali, Sajid, Balaji, Kavitha and Chan, Stephen Lam (2025). Patterns of radiological progression in participants (pts) with embolization-eligible hepatocellular carcinoma (HCC) treated with durvalumab (D) + bevacizumab (B) + transarterial chemoembolization (TACE) and placebos + TACE: EMERALD-1 post hoc analysis. 2025 ASCO Gastrointestinal (GI) Cancers Symposium, San Francisco, CA United States, 23 - 25 January 2025. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2025.43.4_suppl.574

Patterns of radiological progression in participants (pts) with embolization-eligible hepatocellular carcinoma (HCC) treated with durvalumab (D) + bevacizumab (B) + transarterial chemoembolization (TACE) and placebos + TACE: EMERALD-1 post hoc analysis

2024

Conference Publication

Baseline characteristics and molecular testing of Australian patients with IDH1 mutated cholangiocarcinoma: initial results from the phase IIIb ProvIDHe study

Sim, H-W., McLachlan, S-A., Dean, A., Price, T.J., Eastgate, M., Rimassa, L., Mercade, T. Macarulla, Malka, D., Gharbi, H., Robert, R., Sullivan, A. and Vogel, A. (2024). Baseline characteristics and molecular testing of Australian patients with IDH1 mutated cholangiocarcinoma: initial results from the phase IIIb ProvIDHe study. ESMO Asia Congress 2024, Singapore, 6 – 8 December 2024. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.annonc.2024.10.171

Baseline characteristics and molecular testing of Australian patients with IDH1 mutated cholangiocarcinoma: initial results from the phase IIIb ProvIDHe study

2024

Conference Publication

"Signing up for the PRoCESS [Pancreatic cancer Relatives Counselling and Education Support Service] Trial was the most important thing I did as a carer"

Beesley, Vanessa L., Roset, Natalie, Turner, Jane, Yates, Patsy, Wyld, David, Eastgate, Melissa, Chan, Raymond, Collins, Louisa, Stewart, Michelle, Beebe, Hanna, Malt, Maryrose, Kelly, Caroline and Neale, Rachel (2024). "Signing up for the PRoCESS [Pancreatic cancer Relatives Counselling and Education Support Service] Trial was the most important thing I did as a carer". COSA's 51st Annual Scientific Meeting: Bridging gaps, building progress, breaking down disparities, Gold Coast, QLD, Australia, 13 - 15 November 2024. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/ajco.14116

"Signing up for the PRoCESS [Pancreatic cancer Relatives Counselling and Education Support Service] Trial was the most important thing I did as a carer"

2024

Conference Publication

Routine, prospective DPYD genotyping guided dose-individualisation for patients receiving fluoropyrimidines: Implementation, prevalence and patient safety outcomes from a multi-institutional clinical trial

Nalder, Mark, Kulasegaran, Tivya, Lundie, Ben, Woods, Rick, Eastgate, Melissa A., Wyld, David and Burge, Matthew E. (2024). Routine, prospective DPYD genotyping guided dose-individualisation for patients receiving fluoropyrimidines: Implementation, prevalence and patient safety outcomes from a multi-institutional clinical trial. 2024 ASCO Annual Meeting, Chicago, IL, United States, 31 May–4 June 2024. Alexandria, VA, United States: American Society of Clinical Oncology. doi: 10.1200/JCO.2024.42.16_suppl.12121

Routine, prospective DPYD genotyping guided dose-individualisation for patients receiving fluoropyrimidines: Implementation, prevalence and patient safety outcomes from a multi-institutional clinical trial

2023

Conference Publication

Chemoradiotherapy with concurrent durvalumab for the palliative treatment of oligometastatic esophageal and gastroesophageal carcinoma with dysphagia: A single arm phase 2 clinical trial, PALEO

Day, Fiona, Sridharan, Swetha, Michael, Michael, Christophersen, Louise, Moore, Melissa M., Eastgate, Melissa A., Thompson, Stephen, MWEEMPWA, ANGELA, Oldmeadow, Christopher, Fraser, Allison and Martin, Jarad (2023). Chemoradiotherapy with concurrent durvalumab for the palliative treatment of oligometastatic esophageal and gastroesophageal carcinoma with dysphagia: A single arm phase 2 clinical trial, PALEO. 2023 ASCO Annual Meeting, Chicago, IL United States, 2-6 June 2023. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2023.41.16_suppl.tps4172

Chemoradiotherapy with concurrent durvalumab for the palliative treatment of oligometastatic esophageal and gastroesophageal carcinoma with dysphagia: A single arm phase 2 clinical trial, PALEO

2023

Conference Publication

CHARLI: A phase Ib/II trial of ipilimumab-nivolumab-denosumab or nivolumab-denosumab in patients with unresectable stage III and IV melanoma

Lau, Peter Kar Han, Harris, Samuel John, Eastgate, Melissa A., Kee, Damien, Mant, Andrew, Nott, Louise M., Gedye, Craig, Inderjeeth, Andrisha Jade, Underhill, Craig, Weppler, Alison Margaret, Wallace, Roslyn, Lee, Belinda, Au-Yeung, George, Williams, Narelle, Ariza Ospino, Daniel, Gonzales, Louise, Shackleton, Mark J., Lo, Serigne N., McArthur, Grant A. and Sandhu, Shahneen (2023). CHARLI: A phase Ib/II trial of ipilimumab-nivolumab-denosumab or nivolumab-denosumab in patients with unresectable stage III and IV melanoma. 2023 ASCO Annual Meeting, Chicago, IL United States, 2-6 June 2023. Alexandria, VA United States: American Society of Clinical Oncology. doi: 10.1200/jco.2023.41.16_suppl.9525

CHARLI: A phase Ib/II trial of ipilimumab-nivolumab-denosumab or nivolumab-denosumab in patients with unresectable stage III and IV melanoma

2022

Conference Publication

Adjuvant therapy in resected melanoma: Experience from royal brisbane and women's hospital

Turner, Cassie L. and Eastgate, Melissa (2022). Adjuvant therapy in resected melanoma: Experience from royal brisbane and women's hospital. HOBOKEN: WILEY.

Adjuvant therapy in resected melanoma: Experience from royal brisbane and women's hospital

2022

Conference Publication

A multicenter, randomized, double-blind phase III study of HBI-8000 combined with nivolumab versus placebo with nivolumab in patients with unresectable or metastatic melanoma not previously treated with PD-1 or PD-L1 inhibitors

Khushalani, N.I., Shue, H., Gedye, C., Mazumder, A., Sharma, S., Eastgate, M., Majem Tarruella, M., Antonanzas Basa, M., Montaudie, H., Marais-Nieman, R., de la Cruz Merino, L., Clements, A., Mortier, L., Jameson, M., Shojaei, F., Ning, J., Aiyer, L., Gillings, M., Kabbinavar, F. and Ascierto, P. (2022). A multicenter, randomized, double-blind phase III study of HBI-8000 combined with nivolumab versus placebo with nivolumab in patients with unresectable or metastatic melanoma not previously treated with PD-1 or PD-L1 inhibitors. ESMO Asia Congress 2022, Singapore, 2-4 December 2022. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.annonc.2022.10.052

A multicenter, randomized, double-blind phase III study of HBI-8000 combined with nivolumab versus placebo with nivolumab in patients with unresectable or metastatic melanoma not previously treated with PD-1 or PD-L1 inhibitors

2022

Conference Publication

Cost-benefit of pre-treatment dihydropyrimidine dehydrogenase genotyping to individualise fluoropyrimidine-based chemotherapy in a contemporary Australian setting

Kim, Hansoo, Kulasegaran, Tivya, Eastgate, Melissa, Wyld, David, Burge, Matthew and Nalder, Mark (2022). Cost-benefit of pre-treatment dihydropyrimidine dehydrogenase genotyping to individualise fluoropyrimidine-based chemotherapy in a contemporary Australian setting. HOBOKEN: WILEY.

Cost-benefit of pre-treatment dihydropyrimidine dehydrogenase genotyping to individualise fluoropyrimidine-based chemotherapy in a contemporary Australian setting

2022

Conference Publication

Tumour naive circulating tumour DNA (ctDNA) analysis in patients (pts) with resected colorectal cancer (CRC) in the phase III ASCOLT trial

Day, D., Starus, A., Lamik, A., Sieber, O., Begbie, S., Bonaventura, A., Rai, S., Karanth, N., Underhill, C. R., Nott, L. M., Van Hazel, G., Van Hagen, T., Wong, M., Saqib, A., Eastgate, M., Srivastav, R., Chia, J., Toh, H. C., Jones, F. and Segelov, E. (2022). Tumour naive circulating tumour DNA (ctDNA) analysis in patients (pts) with resected colorectal cancer (CRC) in the phase III ASCOLT trial. Annual Meeting of the European-Society-for-Medical-Oncology (ESMO), Electr Network, Sep 09-13, 2022. AMSTERDAM: ELSEVIER. doi: 10.1016/j.annonc.2022.07.518

Tumour naive circulating tumour DNA (ctDNA) analysis in patients (pts) with resected colorectal cancer (CRC) in the phase III ASCOLT trial

2022

Conference Publication

Toxicity and response to ipilimumab and nivolumab in elderly patients with metastatic melanoma: A multicenter retrospective analysis

Pathmanathan, Shivanshan, Babu, Hari S., Dzienis, Marcin Radoslaw, Azer, Mary and Eastgate, Melissa A. (2022). Toxicity and response to ipilimumab and nivolumab in elderly patients with metastatic melanoma: A multicenter retrospective analysis. Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Electr Network, Jun 03-07, 2022. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

Toxicity and response to ipilimumab and nivolumab in elderly patients with metastatic melanoma: A multicenter retrospective analysis

2020

Conference Publication

Psychosocial impacts of COVID-19 on oncology workforces: metro versus regional Australia

Ahern, Elizabeth Stephanie, Gasper, Harry Michael, Chan, Bryan, Roberts, Natasha Anne, Hughes, Brett Gordon Maxwell, Wyld, David, Kennedy, Glen, Eastgate, Melissa A. and Lwin, Zarnie (2020). Psychosocial impacts of COVID-19 on oncology workforces: metro versus regional Australia. 2020 ASCO Quality Care Symposium, Chicago, IL USA, 9-10 October 2020. Alexandria, VA USA: American Society of Clinical Oncology. doi: 10.1200/jco.2020.38.29_suppl.111

Psychosocial impacts of COVID-19 on oncology workforces: metro versus regional Australia

2020

Conference Publication

Emotional impact of COVID-19 preparations on metro and regional cancer workforces in Queensland Australia: "We are all in this together"

Roberts, Natasha Anne, Chan, Bryan, Ahern, Elizabeth Stephanie, Gasper, Harry Michael, Kennedy, Glen, Hughes, Brett Gordon Maxwell, Wyld, David, Eastgate, Melissa A. and Lwin, Zarnie (2020). Emotional impact of COVID-19 preparations on metro and regional cancer workforces in Queensland Australia: "We are all in this together". 2020 ASCO Quality Care Symposium, Chicago, IL USA, 9-10 October 2020. Alexandria, VA USA: American Society of Clinical Oncology. doi: 10.1200/jco.2020.38.29_suppl.44

Emotional impact of COVID-19 preparations on metro and regional cancer workforces in Queensland Australia: "We are all in this together"

2019

Conference Publication

Resistance to immunotherapy is associated with high parenchymal PD1+CD8+/CD8+T cells (PD1tR) driven by tumour CD155

de Oliveira, A. Lepletier, Madore, J., O'donnell, S., Johnston, R. L., Eastgate, M., Mallardo, D., Ascierto, P. A., Massi, D., Merelli, B., Mandala, M., Wilmott, J. S., Bald, T., Stagg, J., Routy, B., Long, G. V., Scolyer, R. A., Waddell, N., Dougall, W. C., Teng, M. W. L. and Smyth, M. (2019). Resistance to immunotherapy is associated with high parenchymal PD1+CD8+/CD8+T cells (PD1tR) driven by tumour CD155. Immuno-Oncology Congress of the European-Society-for-Medical-Oncology (ESMO), Geneva, Switzerland, 11-14 December 2019. Oxford, United Kingdom: Oxford University Press.

Resistance to immunotherapy is associated with high parenchymal PD1+CD8+/CD8+T cells (PD1tR) driven by tumour CD155

2019

Conference Publication

Royal Brisbane MedicalOncology Clinic Activity Review

Kuchel, Anna, Kermond, Anna, Lonton, Jennifer, Wyld, David and Eastgate, Melissa (2019). Royal Brisbane MedicalOncology Clinic Activity Review. COSA's 46th Annual Scientific Meeting, Urological cancer; Age and gender in cancer practice; Digital health in cancer, Adelaide, SA Australia, 12–14 November 2019. Chichester, West Sussex United Kingdom: Wiley-Blackwell.

Royal Brisbane MedicalOncology Clinic Activity Review

2018

Conference Publication

Pushing the accelerator and releasing the brake: A phase I dose escalation study evaluating a LAG-3 fusion protein (eftilagimod alpha), together with pembrolizumab in unresectable or metastatic melanoma

Eastgate, Melissa A., Atkinson, Victoria, Khattak, Muhammad Adnan, Roy, Amitesh Chandra, Haydon, Andrew Mark, Mueller, Christian, Dunkelmann, Tina, Brignone, Chrystelle and Frederic, Triebel (2018). Pushing the accelerator and releasing the brake: A phase I dose escalation study evaluating a LAG-3 fusion protein (eftilagimod alpha), together with pembrolizumab in unresectable or metastatic melanoma. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. doi: 10.1200/JCO.2018.36.15_suppl.e15099

Pushing the accelerator and releasing the brake: A phase I dose escalation study evaluating a LAG-3 fusion protein (eftilagimod alpha), together with pembrolizumab in unresectable or metastatic melanoma