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2025

Journal Article

Poststroke Cardiorespiratory Exercise for Brain Volume and Cognition : A Randomized Clinical Trial

Brodtmann, Amy, Churilov, Leonid, Adkins, Kimberley, Haibe, Ruwayda, Tucker, Stephanie, Khlif, Mohamed Salah, Werden, Emilio, McCambridge, Laura J. E., Telfer, Rachael, Kramer, Sharon, Cardoso, Barbara R., Pase, Matthew, Launder, Nathalie, Egorova-Brumley, Natalia, Hung, Stanley Hughwa, Burrell, Louise M., Williams, Gavin, Thijs, Vincent, Bernhardt, Julie, Johnson, Liam, Hayward, Kathryn S. and PISCES-ZODIAC Investigators (2025). Poststroke Cardiorespiratory Exercise for Brain Volume and Cognition : A Randomized Clinical Trial. JAMA Network Open, 8 (8), e2528907-8. doi: 10.1001/jamanetworkopen.2025.28907

Poststroke Cardiorespiratory Exercise for Brain Volume and Cognition : A Randomized Clinical Trial

2025

Journal Article

Integrated UPper limb and Language Impairment and Functional Training (UPLIFT) after stroke: study protocol for an umbrella Bayesian Optimal Phase IIa clinical trial

Hayward, Kathryn S, Donnan, Geoffrey, Godecke, Erin, Balabanski, Anna, Barker, Ruth, Bernhardt, Julie, Brauer, Sandra, Brodtmann, Amy, Brogan, Emily, Brownsett, Sonia, Chapman, Paul, Copland, David, Cowley, Elise, Dalton, Emily, Ellery, Fiona, Fink, Paul, Garcia Esperon, Carlos, Hill, Annie J, Janssen, Heidi, Kavanagh, Siobhan, Kleinig, Timothy, Olenko, Liudmyla, Quek, Joanne JE, Russell, Trevor, Smith, Moira, Taylor, Lillian, Thijs, Vincent, Tucak, Claire, Turner, John ... Churilov, Leonid (2025). Integrated UPper limb and Language Impairment and Functional Training (UPLIFT) after stroke: study protocol for an umbrella Bayesian Optimal Phase IIa clinical trial. BMJ Neurology Open, 7 (2) e001212, e001212-2. doi: 10.1136/bmjno-2025-001212

Integrated UPper limb and Language Impairment and Functional Training (UPLIFT) after stroke: study protocol for an umbrella Bayesian Optimal Phase IIa clinical trial

2025

Journal Article

Conducting descriptive epidemiology and causal inference studies using observational data: a 10-point primer for stroke researchers

Churilov, Leonid, Hayward, Kathryn, Yogendrakumar, Vignan and Andrew, Nadine (2025). Conducting descriptive epidemiology and causal inference studies using observational data: a 10-point primer for stroke researchers. European Stroke Journal, 10 (2), 307-329. doi: 10.1177/23969873251332118

Conducting descriptive epidemiology and causal inference studies using observational data: a 10-point primer for stroke researchers

2025

Journal Article

Coaching stroke survivors to persevere with practice: an observational behavioural mapping study

Neibling, Bridee, Smith, Moira, Barker, Ruth N. and Hayward, Kathryn S. (2025). Coaching stroke survivors to persevere with practice: an observational behavioural mapping study. Clinical Rehabilitation, 39 (3), 410-420. doi: 10.1177/02692155241304340

Coaching stroke survivors to persevere with practice: an observational behavioural mapping study

2025

Journal Article

Using mechanistic knowledge to appraise contemporary approaches to the rehabilitation of upper limb function following stroke

Carson, Richard G. and Hayward, Kathryn S. (2025). Using mechanistic knowledge to appraise contemporary approaches to the rehabilitation of upper limb function following stroke. Journal of Physiology, 603 (3), 635-650. doi: 10.1113/JP285559

Using mechanistic knowledge to appraise contemporary approaches to the rehabilitation of upper limb function following stroke

2025

Journal Article

SPIRIT-DEFINE explanation and elaboration: recommendations for enhancing quality and impact of early phase dose-finding clinical trials protocols

Ursino, Moreno, Villacampa, Guillermo, Rekowski, Jan, Dimairo, Munyaradzi, Solovyeva, Olga, Ashby, Deborah, Berlin, Jordan, Boix, Oliver, Calvert, Melanie, Chan, An-Wen, Coschi, Courtney H., Evans, Thomas R. Jeffry, Garrett-Mayer, Elizabeth, Golub, Robert M., Guo, Christina, Hayward, Kathryn S., Hopewell, Sally, Isaacs, John D., Ivy, S. Percy, Jaki, Thomas, Kholmanskikh, Olga, Kightley, Andrew, Lee, Shing, Liu, Rong, Mander, Adrian, Marshall, Lynley V., Matcham, James, Patel, Dhrusti, Peck, Richard ... Yap, Christina (2025). SPIRIT-DEFINE explanation and elaboration: recommendations for enhancing quality and impact of early phase dose-finding clinical trials protocols. eClinicalMedicine, 79 102988, 1-41. doi: 10.1016/j.eclinm.2024.102988

SPIRIT-DEFINE explanation and elaboration: recommendations for enhancing quality and impact of early phase dose-finding clinical trials protocols

2025

Journal Article

CONSORT-DEFINE explanation and elaboration: recommendations for enhancing reporting quality and impact of early phase dose-finding clinical trials

Rekowski, Jan, Guo, Christina, Solovyeva, Olga, Dimairo, Munyaradzi, Rouhifard, Mahtab, Patel, Dhrusti, Alger, Emily, Ashby, Deborah, Berlin, Jordan, Boix, Oliver, Calvert, Melanie, Chan, An-Wen, Coschi, Courtney H., de Bono, Johann, Evans, Thomas R. Jeffry, Garrett–Mayer, Elizabeth, Golub, Robert M., Hayward, Kathryn S., Hopewell, Sally, Isaacs, John D., Ivy, S. Percy, Jaki, Thomas, Kholmanskikh, Olga, Kightley, Andrew, Lee, Shing, Liu, Rong, Maia, Israel, Mander, Adrian, Marshall, Lynley V. ... Yap, Christina (2025). CONSORT-DEFINE explanation and elaboration: recommendations for enhancing reporting quality and impact of early phase dose-finding clinical trials. eClinicalMedicine, 79 102987, 1-48. doi: 10.1016/j.eclinm.2024.102987

CONSORT-DEFINE explanation and elaboration: recommendations for enhancing reporting quality and impact of early phase dose-finding clinical trials

2024

Journal Article

ZOom Delivered Intervention Against Cognitive decline (ZODIAC) COVID-19 pandemic adaptations to the Post-Ischaemic Stroke Cardiovascular Exercise Study (PISCES): protocol for a randomised controlled trial of remotely delivered fitness training for brain health

Brodtmann, Amy, Billett, Alex, Telfer, Rachael, Adkins, Kim, White, Laura, McCambridge, Laura J. E., Burrell, Louise M., Thijs, Vincent, Kramer, Sharon, Werden, Emilio, Cardoso, Barbara R., Pase, Matthew, Hung, Stanley Hughwa, Churilov, Leonid, Bernhardt, Julie, Hayward, Kathryn and Johnson, Liam (2024). ZOom Delivered Intervention Against Cognitive decline (ZODIAC) COVID-19 pandemic adaptations to the Post-Ischaemic Stroke Cardiovascular Exercise Study (PISCES): protocol for a randomised controlled trial of remotely delivered fitness training for brain health. Trials, 25 (1) 329, 1. doi: 10.1186/s13063-024-08154-1

ZOom Delivered Intervention Against Cognitive decline (ZODIAC) COVID-19 pandemic adaptations to the Post-Ischaemic Stroke Cardiovascular Exercise Study (PISCES): protocol for a randomised controlled trial of remotely delivered fitness training for brain health

2024

Journal Article

Adaptive trials in stroke

Hayward, Kathryn S., Dalton, Emily J., Campbell, Bruce C. V., Khatri, Pooja, Dukelow, Sean P., Johns, Hannah, Walter, Silke, Yogendrakumar, Vignan, Pandian, Jeyaraj D., Sacco, Simona, Bernhardt, Julie, Parsons, Mark W., Saver, Jeffrey L. and Churilov, Leonid (2024). Adaptive trials in stroke. Neurology, 103 (8) e209876, e209876. doi: 10.1212/WNL.0000000000209876

Adaptive trials in stroke

2024

Journal Article

Considerations for developing complex post-stroke upper limb behavioural interventions: an international qualitative study

Wingfield, Matthew, Hughes, Gemma, Fini, Natalie A., Brodtmann, Amy, Williams, Gavin and Hayward, Kathryn S. (2024). Considerations for developing complex post-stroke upper limb behavioural interventions: an international qualitative study. Clinical Rehabilitation, 38 (9), 1249-1263. doi: 10.1177/02692155241265271

Considerations for developing complex post-stroke upper limb behavioural interventions: an international qualitative study

2024

Journal Article

How to work effectively with stroke survivors throughout the research process

Lynch, Elizabeth A., Booth, Brenda, O’Malley, Adrian, Hayward, Kathryn S., Mason, Gillian, Shiggins, Ciara and Wong, Dana (2024). How to work effectively with stroke survivors throughout the research process. Stroke, 55 (9), e258-e261. doi: 10.1161/strokeaha.124.047193

How to work effectively with stroke survivors throughout the research process

2024

Journal Article

Modulation of the association between corticospinal tract ramage and outcome after stroke by white matter hyperintensities

Ferris, Jennifer K., Tavenner, Bethany P., Barisano, Giuseppe, Brodtmann, Amy, Buetefisch, Cathrin M., Conforto, Adriana B., Donnelly, Miranda R., Egorova-Brumley, Natalia, Hayward, Kathryn S., Khlif, Mohamed Salah, Revill, Kate P., Zavaliangos-Petropulu, Artemis, Boyd, Lara and Liew, Sook-Lei (2024). Modulation of the association between corticospinal tract ramage and outcome after stroke by white matter hyperintensities. Neurology, 102 (10) e209387, e209387. doi: 10.1212/wnl.0000000000209387

Modulation of the association between corticospinal tract ramage and outcome after stroke by white matter hyperintensities

2024

Journal Article

Prevalence of Arm Weakness, Pre-Stroke Outcomes and Other Post-Stroke Impairments Using Routinely Collected Clinical Data on an Acute Stroke Unit

Dalton, Emily J., Jamwal, Rebecca, Augoustakis, Lia, Hill, Emma, Johns, Hannah, Thijs, Vincent and Hayward, Kathryn S. (2024). Prevalence of Arm Weakness, Pre-Stroke Outcomes and Other Post-Stroke Impairments Using Routinely Collected Clinical Data on an Acute Stroke Unit. Neurorehabilitation and Neural Repair, 38 (2), 148-160. doi: 10.1177/15459683241229676

Prevalence of Arm Weakness, Pre-Stroke Outcomes and Other Post-Stroke Impairments Using Routinely Collected Clinical Data on an Acute Stroke Unit

2024

Journal Article

Control intervention design for preclinical and clinical trials: consensus-based core recommendations from the third Stroke Recovery and Rehabilitation Roundtable

Hayward, Kathryn S., Dalton, Emily J., Barth, Jessica, Brady, Marian, Cherney, Leora R., Churilov, Leonid, Clarkson, Andrew N., Dawson, Jesse, Dukelow, Sean P., Feys, Peter, Hackett, Maree, Zeiler, Steve R. and Lang, Catherine E. (2024). Control intervention design for preclinical and clinical trials: consensus-based core recommendations from the third Stroke Recovery and Rehabilitation Roundtable. International Journal of Stroke, 19 (2), 169-179. doi: 10.1177/17474930231199336

Control intervention design for preclinical and clinical trials: consensus-based core recommendations from the third Stroke Recovery and Rehabilitation Roundtable

2024

Journal Article

Control intervention design for preclinical and clinical trials: Consensus-based core recommendations from the third Stroke Recovery and Rehabilitation Roundtable

Hayward, Kathryn S, Dalton, Emily J, Barth, Jessica, Brady, Marian, Cherney, Leora R, Churilov, Leonid, Clarkson, Andrew N, Dawson, Jesse, Dukelow, Sean P, Feys, Peter, Hackett, Maree, Zeiler, Steve R and Lang, Catherine E (2024). Control intervention design for preclinical and clinical trials: Consensus-based core recommendations from the third Stroke Recovery and Rehabilitation Roundtable. Neurorehabilitation and Neural Repair, 38 (1), 30-40. doi: 10.1177/15459683231209162

Control intervention design for preclinical and clinical trials: Consensus-based core recommendations from the third Stroke Recovery and Rehabilitation Roundtable

2023

Journal Article

Clinical and systems of care factors contributing to individual patient decision-making for early mobilization post-stroke

Rethnam, Venesha, Hayward, Kathryn S., Johns, Hannah, Carvalho, Lilian B., Churilov, Leonid and Bernhardt, Julie (2023). Clinical and systems of care factors contributing to individual patient decision-making for early mobilization post-stroke. Frontiers in Stroke, 2 1293942, 1-9. doi: 10.3389/fstro.2023.1293942

Clinical and systems of care factors contributing to individual patient decision-making for early mobilization post-stroke

2023

Journal Article

Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance

Yap, Christina, Solovyeva, Olga, de Bono, Johann, Rekowski, Jan, Patel, Dhrusti, Jaki, Thomas, Mander, Adrian, Evans, Thomas R Jeffry, Peck, Richard, Hayward, Kathryn S, Hopewell, Sally, Ursino, Moreno, Rantell, Khadija Rerhou, Calvert, Melanie, Lee, Shing, Kightley, Andrew, Ashby, Deborah, Chan, An-Wen, Garrett-Mayer, Elizabeth, Isaacs, John D, Golub, Robert, Kholmanskikh, Olga, Richards, Dawn, Boix, Oliver, Matcham, James, Seymour, Lesley, Ivy, S Percy, Marshall, Lynley V, Hommais, Antoine ... Weir, Christopher J (2023). Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance. BMJ, 383 e076387, e076387. doi: 10.1136/bmj-2023-076387

Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance

2023

Journal Article

Enhancing quality and impact of early phase dose-finding clinical trial protocols: SPIRIT Dose-finding Extension (SPIRIT-DEFINE) guidance

Yap, Christina, Rekowski, Jan, Ursino, Moreno, Solovyeva, Olga, Patel, Dhrusti, Dimairo, Munyaradzi, Weir, Christopher J, Chan, An-Wen, Jaki, Thomas, Mander, Adrian, Evans, Thomas R Jeffry, Peck, Richard, Hayward, Kathryn S, Calvert, Melanie, Rantell, Khadija Rerhou, Lee, Shing, Kightley, Andrew, Hopewell, Sally, Ashby, Deborah, Garrett-Mayer, Elizabeth, Isaacs, John, Golub, Robert, Kholmanskikh, Olga, Richards, Dawn P, Boix, Oliver, Matcham, James, Seymour, Lesley, Ivy, S Percy, Marshall, Lynley V ... de Bono, Johann (2023). Enhancing quality and impact of early phase dose-finding clinical trial protocols: SPIRIT Dose-finding Extension (SPIRIT-DEFINE) guidance. BMJ, 383 e076386, e076386-383. doi: 10.1136/bmj-2023-076386

Enhancing quality and impact of early phase dose-finding clinical trial protocols: SPIRIT Dose-finding Extension (SPIRIT-DEFINE) guidance

2023

Journal Article

Stroke survivors' perspectives on decision-making about rehabilitation and the prospect of taking recovery-promoting drugs: A qualitative study

Firth, Nerida, Hayward, Kathryn S., Bernhardt, Julie, Ray, Robin and Barker, Ruth N. (2023). Stroke survivors' perspectives on decision-making about rehabilitation and the prospect of taking recovery-promoting drugs: A qualitative study. Exploratory Research in Clinical and Social Pharmacy, 11 100297, 1-7. doi: 10.1016/j.rcsop.2023.100297

Stroke survivors' perspectives on decision-making about rehabilitation and the prospect of taking recovery-promoting drugs: A qualitative study

2023

Journal Article

Aspiring to restore arm and hand function after stroke

Hayward, Kathryn S and Bernhardt, Julie (2023). Aspiring to restore arm and hand function after stroke. The Lancet Neurology, 22 (6), 464-465. doi: 10.1016/S1474-4422(23)00150-3

Aspiring to restore arm and hand function after stroke