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2021 Journal Article An optimized high-throughput immuno-plaque assay for SARS-CoV-2Amarilla, Alberto A., Modhiran, Naphak, Setoh, Yin Xiang, Peng, Nias Y. G., Sng, Julian D. J., Liang, Benjamin, McMillan, Christopher L. D., Freney, Morgan E, Cheung, Stacey T. M., Chappell, Keith J., Khromykh, Alexander A., Young, Paul R. and Watterson, Daniel (2021). An optimized high-throughput immuno-plaque assay for SARS-CoV-2. Frontiers in Microbiology, 12 625136, 625136. doi: 10.3389/fmicb.2021.625136 |
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2021 Journal Article Adjuvant selection for influenza and RSV prefusion subunit vaccinesIsaacs, Ariel, Li, Zheyi, Cheung, Stacey T. M., Wijesundara, Danushka K., McMillan, Christopher L. D., Modhiran, Naphak, Young, Paul R., Ranasinghe, Charani, Watterson, Daniel and Chappell, Keith J. (2021). Adjuvant selection for influenza and RSV prefusion subunit vaccines. Vaccines, 9 (2) 71, 1-14. doi: 10.3390/vaccines9020071 |
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2021 Journal Article A broadly protective antibody that targets the flavivirus NS1 proteinModhiran, Naphak, Song, Hao, Liu, Lidong, Bletchly, Cheryl, Brillault, Lou, Amarilla, Alberto A., Xu, Xiaoying, Qi, Jianxun, Chai, Yan, Cheung, Stacey T. M., Traves, Renee, Setoh, Yin Xiang, Bibby, Summa, Scott, Connor A. P., Freney, Morgan E., Newton, Natalee D., Khromykh, Alexander A., Chappell, Keith J., Muller, David A., Stacey, Katryn J., Landsberg, Michael J., Shi, Yi, Gao, George F., Young, Paul R. and Watterson, Daniel (2021). A broadly protective antibody that targets the flavivirus NS1 protein. Science, 371 (6525), 190-194. doi: 10.1126/science.abb9425 |
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2021 Journal Article The next generation of influenza vaccines: towards a universal solutionMcMillan, Christopher L. D., Young, Paul R., Watterson, Daniel and Chappell, Keith J. (2021). The next generation of influenza vaccines: towards a universal solution. Vaccines, 9 (1) 26, 1-20. doi: 10.3390/vaccines9010026 |
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2020 Journal Article Rapid response subunit vaccine design in the absence of structural informationWijesundara, Danushka K., Avumegah, Michael S., Lackenby, Julia, Modhiran, Naphak, Isaacs, Ariel, Young, Paul R., Watterson, Daniel and Chappell, Keith J. (2020). Rapid response subunit vaccine design in the absence of structural information. Frontiers in Immunology, 11 592370, 592370. doi: 10.3389/fimmu.2020.592370 |
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2020 Journal Article Micro-fusion inhibition tests: quantifying antibody neutralization of virus-mediated cell–cell fusionThakur, Nazia, Conceicao, Carina, Isaacs, Ariel, Human, Stacey, Modhiran, Naphak, McLean, Rebecca K., Pedrera, Miriam, Tan, Tiong Kit, Rijal, Pramila, Townsend, Alain, Taylor, Geraldine, Young, Paul R., Watterson, Daniel, Chappell, Keith J., Graham, Simon P. and Bailey, Dalan (2020). Micro-fusion inhibition tests: quantifying antibody neutralization of virus-mediated cell–cell fusion. Journal of General Virology, 102 (1) 001506. doi: 10.1099/jgv.0.001506 |
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2020 Journal Article Genetic, morphological and antigenic relationships between mesonivirus isolates from Australian mosquitoes and evidence for their horizontal transmissionNewton, Natalee D., Colmant, Agathe M. G., O’Brien, Caitlin A., Ledger, Emma, Paramitha, Devina, Bielefeldt-Ohmann, Helle, Watterson, Daniel, McLean, Breeanna J., Hall-Mendelin, Sonja, Warrilow, David, van den Hurk, Andrew F., Liu, Wenjun, Hoare, Christina, Kizu, Joanne R., Gauci, Penelope J., Haniotis, John, Doggett, Stephen L., Shaban, Babak, Johansen, Cheryl A., Hall, Roy A. and Hobson-Peters, Jody (2020). Genetic, morphological and antigenic relationships between mesonivirus isolates from Australian mosquitoes and evidence for their horizontal transmission. Viruses, 12 (10) 1159, 1159. doi: 10.3390/v12101159 |
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2020 Journal Article A unique relative of Rotifer birnavirus Isolated from Australian mosquitoesO’Brien, Caitlin A., Pegg, Cassandra L., Nouwens, Amanda S., Bielefeldt-Ohmann, Helle, Huang, Bixing, Warrilow, David, Harrison, Jessica J., Haniotis, John, Schulz, Benjamin L., Paramitha, Devina, Colmant, Agathe M. G., Newton, Natalee D., Doggett, Stephen L., Watterson, Daniel, Hobson-Peters, Jody and Hall, Roy A. (2020). A unique relative of Rotifer birnavirus Isolated from Australian mosquitoes. Viruses, 12 (9) 1056, 1056. doi: 10.3390/v12091056 |
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2020 Other Outputs Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 By Disrupting The Spike-ACE2 interactionGuimond, Scott E., Mycroft-West, Courtney J., Gandhi, Neha S., Tree, Julia A., Le, Thuy T, Spalluto, C. Mirella, Humbert, Maria V., Buttigieg, Karen R., Coombes, Naomi, Elmore, Michael J., Nyström, Kristina, Said, Joanna, Setoh, Yin Xiang, Amarilla, Alberto A., Modhiran, Naphak, Sng, Julian D.J., Chhabra, Mohit, Young, Paul R., Lima, Marcelo A., A.Yates, Edwin, Karlsson, Richard, Miller, Rebecca L., Chen, Yen-Hsi, Bagdonaite, Ieva, Yang, Zhang, Stewart, James, Hammond, Edward, Dredge, Keith, Wilkinson, Tom M.A. ... Turnbull, Jeremy E. (2020). Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 By Disrupting The Spike-ACE2 interaction. doi: 10.1101/2020.06.24.169334 |
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2020 Other Outputs Potent neutralization of clinical isolates of SARS-CoV-2 D614 and G614 variants by a monomeric, sub-nanomolar affinity NanobodyNieto, Guillermo Valenzuela, Jara, Ronald, Watterson, Daniel, Modhiran, Naphak, Amarilla, Alberto A, Himelreichs, Johanna, Khromykh, Alexander A., Salinas, Constanza, Pinto, Teresa, Cheuquemilla, Yorka, Margolles, Yago, del Rey, Natalia López González, Miranda-Chacon, Zaray, Cuevas, Alexei, Berking, Anne, Deride, Camila, González-Moraga, Sebastián, Mancilla, Héctor, Maturana, Daniel, Langer, Andreas, Toledo, Juan Pablo, Müller, Ananda, Uberti, Benjamín, Krall, Paola, Ehrenfeld, Pamela, Blesa, Javier, Chana-Cuevas, Pedro, Rehren, German, Schwefel, David ... Rojas-Fernandez, Alejandro (2020). Potent neutralization of clinical isolates of SARS-CoV-2 D614 and G614 variants by a monomeric, sub-nanomolar affinity Nanobody. doi: 10.1101/2020.06.09.137935 |
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2020 Other Outputs Distinct systems serology features in children, elderly and COVID patientsSelva, Kevin J., van de Sandt, Carolien E., Lemke, Melissa M., Lee, Christina Y., Shoffner, Suzanne K., Chua, Brendon Y., Nguyen, Thi H.O., Rowntree, Louise C., Hensen, Luca, Koutsakos, Marios, Wong, Chinn Yi, Jackson, David C., Flanagan, Katie L., Crowe, Jane, Cheng, Allen C., Doolan, Denise L., Amanat, Fatima, Krammer, Florian, Chappell, Keith, Modhiran, Naphak, Watterson, Daniel, Young, Paul, Wines, Bruce, Hogarth, P. Mark, Esterbauer, Robyn, Kelly, Hannah G., Tan, Hyon-Xhi, Juno, Jennifer A., Wheatley, Adam K. ... Chung, Amy W. (2020). Distinct systems serology features in children, elderly and COVID patients. doi: 10.1101/2020.05.11.20098459 |
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2020 Journal Article Bovine herpesvirus-4-vectored delivery of nipah virus glycoproteins enhances T cell immunogenicity in pigsPedrera, Miriam, Macchi, Francesca, McLean, Rebecca K., Franceschi, Valentina, Thakur, Nazia, Russo, Luca, Medfai, Lobna, Todd, Shawn, Tchilian, Elma Z., Audonnet, Jean-Christophe, Chappell, Keith, Isaacs, Ariel, Watterson, Daniel, Young, Paul R., Marsh, Glenn A., Bailey, Dalan, Graham, Simon P. and Donofrio, Gaetano (2020). Bovine herpesvirus-4-vectored delivery of nipah virus glycoproteins enhances T cell immunogenicity in pigs. Vaccines, 8 (1) 115, 115. doi: 10.3390/vaccines8010115 |
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2020 Journal Article Flow-cytometry detection of fluorescent magnetic nanoparticle clusters increases sensitivity of dengue immunoassaySanjaya, K.C., Ranzoni, Andrea, Hung, Jacky, Blaskovich, Mark A.T., Watterson, Daniel, Young, Paul R. and Cooper, Matthew A. (2020). Flow-cytometry detection of fluorescent magnetic nanoparticle clusters increases sensitivity of dengue immunoassay. Analytica Chimica Acta, 1107, 85-91. doi: 10.1016/j.aca.2020.02.007 |
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2020 Journal Article Novel monoclonal antibodies against Australian strains of negeviruses and insights into virus structure, replication and host -restrictionColmant, Agathe M. G., O'Brien, Caitlin A., Newton, Natalee D., Watterson, Daniel, Hardy, Joshua, Coulibaly, Fasséli, Bielefeldt-Ohmann, Helle, Warrilow, David, Huang, Bixing, Paramitha, Devina, Harrison, Jessica J., Hall, Roy A. and Hobson-Peters, Jody (2020). Novel monoclonal antibodies against Australian strains of negeviruses and insights into virus structure, replication and host -restriction. Journal of General Virology, 101 (4), 440-452. doi: 10.1099/jgv.0.001388 |
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2019 Journal Article A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virusHobson-Peters, Jody, Harrison, Jessica J., Watterson, Daniel, Hazlewood, Jessamine E., Vet, Laura J., Newton, Natalee D., Warrilow, David, Colmant, Agathe M. G., Taylor, Carmel, Huang, Bixing, Piyasena, Thisun B. H., Chow, Weng Kong, Setoh, Yin Xiang, Tang, Bing, Nakayama, Eri, Yan, Kexin, Amarilla, Alberto A., Wheatley, Sarah, Moore, Peter R., Finger, Mitchell, Kurucz, Nina, Modhiran, Naphak, Young, Paul R., Khromykh, Alexander A., Bielefeldt-Ohmann, Helle, Suhrbier, Andreas and Hall, Roy A. (2019). A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virus. Science Translational Medicine, 11 (522) eaax7888, 1-15. doi: 10.1126/scitranslmed.aax7888 |
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2019 Journal Article Efficient delivery of dengue virus subunit vaccines to the skin by microprojection arraysMuller, David A., Depelsenaire, Alexandra C. I., Shannon, Ashleigh E., Watterson, Daniel, Corrie, Simon R., Owens, Nick S., Agyei-Yeboah, Christiana, Cheung, Stacey T. M., Zhang, Jin, Fernando, Germain J. P., Kendall, Mark A. F. and Young, Paul R. (2019). Efficient delivery of dengue virus subunit vaccines to the skin by microprojection arrays. Vaccines, 7 (4) 189, 189. doi: 10.3390/vaccines7040189 |
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2019 Journal Article Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyonTan, Yuen P., Xue, Yongbo, Savchenko, Andrei I., Houston, Sevan D., Modhiran, Naphak, McMillan, Christopher L. D., Boyle, Glen M., Bernhardt, Paul V., Young, Paul R., Watterson, Daniel and Williams, Craig M. (2019). Basimarols A, B, and C, Highly Oxygenated Pimarane Diterpenoids from Basilicum polystachyon. Journal of Natural Products, 82 (10) acs.jnatprod.9b00522, 2828-2834. doi: 10.1021/acs.jnatprod.9b00522 |
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2019 Journal Article Dual targeting of dengue virus virions and NS1 protein with the heparan sulfate mimic PG545Modhiran, Naphak, Gandhi, Neha S., Wimmer, Norbert, Cheung, Stacey, Stacey, Katryn, Young, Paul R., Ferro, Vito and Watterson, Daniel (2019). Dual targeting of dengue virus virions and NS1 protein with the heparan sulfate mimic PG545. Antiviral Research, 168, 121-127. doi: 10.1016/j.antiviral.2019.05.004 |
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2019 Journal Article Determinants of Zika virus host tropism uncovered by deep mutational scanningSetoh, Yin Xiang, Amarilla, Alberto A., Peng, Nias Y. G., Griffiths, Rebecca E., Carrera, Julio, Freney, Morgan E., Nakayama, Eri, Ogawa, Shinya, Watterson, Daniel, Modhiran, Naphak, Nanyonga, Faith Elizabeth, Torres, Francisco J., Slonchak, Andrii, Periasamy, Parthiban, Prow, Natalie A., Tang, Bing, Harrison, Jessica, Hobson-Peters, Jody, Cuddihy, Thom, Cooper-White, Justin, Hall, Roy A., Young, Paul R., Mackenzie, Jason M., Wolvetang, Ernst, Bloom, Jesse D., Suhrbier, Andreas and Khromykh, Alexander A. (2019). Determinants of Zika virus host tropism uncovered by deep mutational scanning. Nature Microbiology, 4 (5), 876-887. doi: 10.1038/s41564-019-0399-4 |
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2019 Journal Article Stachyonic acid: a dengue virus inhibitor from Basilicum polystachyonTan, Yuen P., Houston, Sevan D., Modhiran, Naphak, Savchenko, Andrei I., Boyle, Glen M., Young, Paul R., Watterson, Daniel and Williams, Craig M. (2019). Stachyonic acid: a dengue virus inhibitor from Basilicum polystachyon. Chemistry – A European Journal, 25 (22) chem.201900591, 5664-5667. doi: 10.1002/chem.201900591 |
