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2019

Journal Article

STXBP1 encephalopathy: connecting neurodevelopmental disorders with α-synucleinopathies?

Lanoue, Vanessa, Chai, Ye Jin, Brouillet, Julie Z., Weckhuysen, Sarah, Palmer, Elizabeth E., Collins, Brett M. and Meunier, Frederic A. (2019). STXBP1 encephalopathy: connecting neurodevelopmental disorders with α-synucleinopathies?. Neurology, 93 (3), 114-123. doi: 10.1212/WNL.0000000000007786

STXBP1 encephalopathy: connecting neurodevelopmental disorders with α-synucleinopathies?

2019

Conference Publication

Unraveling Munc18/Syntaxin1 nanoscale organisation dynamics in health and disease

Meunier, F. (2019). Unraveling Munc18/Syntaxin1 nanoscale organisation dynamics in health and disease. ISN-ASN Meeting, Montreal, QC, Canada, 4 - 8 August 2019. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jnc.14780

Unraveling Munc18/Syntaxin1 nanoscale organisation dynamics in health and disease

2019

Journal Article

Frontotemporal dementia mutant Tau promotes aberrant Fyn nanoclustering in hippocampal dendritic spines

Padmanabhan, Pranesh, Martínez-Mármol, Ramón, Xia, Di, Götz, Jürgen and Meunier, Frédéric A. (2019). Frontotemporal dementia mutant Tau promotes aberrant Fyn nanoclustering in hippocampal dendritic spines. eLife, 8 e45040. doi: 10.7554/elife.45040

Frontotemporal dementia mutant Tau promotes aberrant Fyn nanoclustering in hippocampal dendritic spines

2019

Journal Article

Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2

Brennan, Faith H., Jogia, Trisha, Gillespie, Ellen R., Blomster, Linda V., Li, Xaria X., Nowlan, Bianca, Williams, Gail M., Jacobson, Esther, Osborne, Geoff W., Meunier, Frederic A., Taylor, Stephen M., Campbell, Kate E., MacDonald, Kelli P.A., Levesque, Jean-Pierre, Woodruff, Trent M. and Ruitenberg, Marc J. (2019). Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2. JCI Insight, 4 (9) e98254. doi: 10.1172/jci.insight.98254

Complement receptor C3aR1 controls neutrophil mobilization following spinal cord injury through physiological antagonism of CXCR2

2019

Journal Article

Need for speed: Super-resolving the dynamic nanoclustering of syntaxin-1 at exocytic fusion sites

Padmanabhan, Pranesh, Bademosi, Adekunle T., Kasula, Ravikiran, Lauwers, Elsa, Verstreken, Patrik and Meunier, Frédéric A. (2019). Need for speed: Super-resolving the dynamic nanoclustering of syntaxin-1 at exocytic fusion sites. Neuropharmacology, 169 107554, 107554. doi: 10.1016/j.neuropharm.2019.02.036

Need for speed: Super-resolving the dynamic nanoclustering of syntaxin-1 at exocytic fusion sites

2019

Journal Article

VAMP2 Binding to Munc18-1 Domain 3a Controls the Nanoscale Reorganization of the Plasma Membrane and Vesicle Interface During Vesicular Priming

Kasula, Ravikiran, Blum, Ailisa, Salla-Martret, Merce, Chai, Ye Jin, Jiang, Anmin, Wallis, Tristan P., Gormal, Rachel S., Brouillet, Julie Z., Padmanabhan, Pranesh, Weeratunga, Saroja K., Livingstone, Emma K., Mollazade, Mahdie, Joensuu, Merja, Martínez-Mármol, Ramón, Collins, Brett M. and Meunier, Frederic (2019). VAMP2 Binding to Munc18-1 Domain 3a Controls the Nanoscale Reorganization of the Plasma Membrane and Vesicle Interface During Vesicular Priming. SSRN Electronic Journal. doi: 10.2139/ssrn.3362260

VAMP2 Binding to Munc18-1 Domain 3a Controls the Nanoscale Reorganization of the Plasma Membrane and Vesicle Interface During Vesicular Priming

2018

Journal Article

Actin remodeling in regulated exocytosis: toward a mesoscopic view

Li, Pin, Bademosi, Adekunle T., Luo, Jincai and Meunier, Frederic A. (2018). Actin remodeling in regulated exocytosis: toward a mesoscopic view. Trends in Cell Biology, 28 (9), 685-697. doi: 10.1016/j.tcb.2018.04.004

Actin remodeling in regulated exocytosis: toward a mesoscopic view

2018

Journal Article

A growth hormone receptor SNP promotes lung cancer by impairment of SOCS2-mediated degradation

Chhabra, Y., Wong, H. Y., Nikolajsen, L. F., Steinocher, H., Papadopulos, A., Tunny, K. A., Meunier, F. A., Smith, A. G., Kragelund, B. B., Brooks, A. J. and Waters, M. J. (2018). A growth hormone receptor SNP promotes lung cancer by impairment of SOCS2-mediated degradation. Oncogene, 37 (4), 489-501. doi: 10.1038/onc.2017.352

A growth hormone receptor SNP promotes lung cancer by impairment of SOCS2-mediated degradation

2018

Journal Article

In vivo single-molecule tracking at the Drosophila presynaptic motor nerve terminal

Bademosi, Adekunle T., Lauwers, Elsa, Amor, Rumelo, Verstreken, Patrik, van Swinderen, Bruno and Meunier, Frédéric A (2018). In vivo single-molecule tracking at the Drosophila presynaptic motor nerve terminal. Journal of Visualized Experiments, 2018 (131) e56952. doi: 10.3791/56952

In vivo single-molecule tracking at the Drosophila presynaptic motor nerve terminal

2018

Journal Article

Trapping of Syntaxin1a in Presynaptic Nanoclusters by a Clinically Relevant General Anesthetic

Bademosi, Adekunle T. , Steeves, James, Karunanithi, Shanker, Zalucki, Oressia H, Gormal, Rachel S, Liu, Shu, Lauwers, Elsa, Verstreken, Patrik, Anggono, Victor, Meunier, Frederic A and van Swinderen, Bruno (2018). Trapping of Syntaxin1a in Presynaptic Nanoclusters by a Clinically Relevant General Anesthetic. Cell reports, 22 (2), 427-440. doi: 10.1016/j.celrep.2017.12.054

Trapping of Syntaxin1a in Presynaptic Nanoclusters by a Clinically Relevant General Anesthetic

2018

Conference Publication

Super-resolving botulinum neurotoxin type A molecules: from surface landing to internalization in synaptic vesicles

Joensuu, Merja, Blum, Ailisa, Mollazade, Mahdie, Lanoue, Vanessa, Padmanabhan, Pranesh, Small, Christopher, Mahrhold, Stefan, Krez, Nadja, Rummel, Andreas and Meunier, Frederic A. (2018). Super-resolving botulinum neurotoxin type A molecules: from surface landing to internalization in synaptic vesicles. TOXINS 2019: Basic Science and Clinical Aspects of Botulinum and Other Neurotoxins, Copenhagen, Denmark, 16-19 January 2019. Kidlington, Oxford, United Kingdom: Pergamon Press. doi: 10.1016/j.toxicon.2018.11.122

Super-resolving botulinum neurotoxin type A molecules: from surface landing to internalization in synaptic vesicles

2017

Journal Article

Amyloid-β and tau complexity - towards improved biomarkers and targeted therapies

Polanco, Juan Carlos, Li, Chuanzhou, Bodea, Liviu-Gabriel, Martinez-Marmol, Ramon, Meunier, Frederic A and Götz, Jürgen (2017). Amyloid-β and tau complexity - towards improved biomarkers and targeted therapies. Nature reviews. Neurology, 14 (1), 22-40. doi: 10.1038/nrneurol.2017.162

Amyloid-β and tau complexity - towards improved biomarkers and targeted therapies

2017

Journal Article

G-protein-coupled inwardly rectifying potassium (GIRK) channel activation by the p75 neurotrophin receptor is required for amyloid beta toxicity

May, Linda M., Anggono, Victor, Gooch, Helen M., Jang, Se E., Matusica, Dusan, Kerbler, Georg M., Meunier, Frederic A., Sah, Pankaj and Coulson, Elizabeth J. (2017). G-protein-coupled inwardly rectifying potassium (GIRK) channel activation by the p75 neurotrophin receptor is required for amyloid beta toxicity. Frontiers in Neuroscience, 11 (455) 455. doi: 10.3389/fnins.2017.00455

G-protein-coupled inwardly rectifying potassium (GIRK) channel activation by the p75 neurotrophin receptor is required for amyloid beta toxicity

2017

Journal Article

ENA/VASP proteins regulate exocytosis by mediating myosin VI-dependent recruitment of secretory granules to the cortical actin network

Tomatis, Vanesa M., Josh, Peter, Papadopulos, Andreas, Gormal, Rachel S., Lanoue, Vanessa, Martin, Sally and Meunier, Frédéric A. (2017). ENA/VASP proteins regulate exocytosis by mediating myosin VI-dependent recruitment of secretory granules to the cortical actin network. Molecular and Cellular Neuroscience, 84, 100-111. doi: 10.1016/j.mcn.2017.07.005

ENA/VASP proteins regulate exocytosis by mediating myosin VI-dependent recruitment of secretory granules to the cortical actin network

2017

Journal Article

A role for tropomyosins in activity-dependent bulk endocytosis?

Gormal, R. S., Valmas, N., Fath, T. and Meunier, F. A. (2017). A role for tropomyosins in activity-dependent bulk endocytosis?. Molecular and Cellular Neuroscience, 84, 112-118. doi: 10.1016/j.mcn.2017.04.003

A role for tropomyosins in activity-dependent bulk endocytosis?

2017

Journal Article

The SAC1 domain in synaptojanin is required for autophagosome maturation at presynaptic terminals

Vanhauwaert, Roeland, Kuenen, Sabine, Masius, Roy, Bademosi, Adekunle, Manetsberger, Julia, Schoovaerts, Nils, Bounti, Laura, Gontcharenko, Serguei, Swerts, Jef, Vilain, Sven, Picillo, Marina, Barone, Paolo, Munshi, Shashini T., de Vrij, Femke M. S., Kushner, Steven A., Gounko, Natalia V., Mandemakers, Wim, Bonifati, Vincenzo, Meunier, Frederic A., Soukup, Sandra‐Fausia and Verstreken, Patrik (2017). The SAC1 domain in synaptojanin is required for autophagosome maturation at presynaptic terminals. EMBO Journal, 36 (10), 1392-1411. doi: 10.15252/embj.201695773

The SAC1 domain in synaptojanin is required for autophagosome maturation at presynaptic terminals

2017

Journal Article

Comparative analyses of glycerotoxin expression unveil a novel structural organization of the bloodworm venom system

Richter, Sandy, Helm, Conrad, Meunier, Frederic A., Hering, Lars, Campbell, Lahcen I., Drukewitz, Stephan H., Undheim, Eivind A. B., Jenner, Ronald A., Schiavo, Giampietro and Bleidorn, Christoph (2017). Comparative analyses of glycerotoxin expression unveil a novel structural organization of the bloodworm venom system. BMC Evolutionary Biology, 17 (1) 64, 64. doi: 10.1186/s12862-017-0904-4

Comparative analyses of glycerotoxin expression unveil a novel structural organization of the bloodworm venom system

2017

Journal Article

Erratum: In vivo single-molecule imaging of syntaxin1A reveals polyphosphoinositide- and activity-dependent trapping in presynaptic nanoclusters

Bademosi, Adekunle T., Lauwers, Elsa, Padmanabhan, Pranesh, Odierna, Lorenzo, Chai, Ye Jin, Papadopulos, Andreas, Goodhill, Geoffrey J., Verstreken, Patrik, van Swinderen, Bruno and Meunier, Frédéric A (2017). Erratum: In vivo single-molecule imaging of syntaxin1A reveals polyphosphoinositide- and activity-dependent trapping in presynaptic nanoclusters. Nature Communications, 8 (1) 14492. doi: 10.1038/ncomms14492

Erratum: In vivo single-molecule imaging of syntaxin1A reveals polyphosphoinositide- and activity-dependent trapping in presynaptic nanoclusters

2017

Conference Publication

Nanoscale imaging of botulinum neurotoxin type a retrograde axonal trafficking

Harper, Callista B., Wang, Tong, Joensuu, Merja, Papadopulos, Andreas and Meunier, Frederic A. (2017). Nanoscale imaging of botulinum neurotoxin type a retrograde axonal trafficking. TOXINS: Basic Science and Clinical Aspects of Botulinum and other Neurotoxins, Madrid, Spain, 18-21 January 2017. Oxford, United Kingdom: Pergamon Press. doi: 10.1016/j.toxicon.2016.11.106

Nanoscale imaging of botulinum neurotoxin type a retrograde axonal trafficking

2017

Book Chapter

New developments in free fatty acids and lysophospholipids: decoding the role of phospholipases in exocytosis

Narayana, Vinod K., Kvaskoff, David and Meunier, Frederic A. (2017). New developments in free fatty acids and lysophospholipids: decoding the role of phospholipases in exocytosis. Lipidomics of stem cells. (pp. 191-206) edited by Alice Pebay and Raymond C.B. Wong. Cham, Switerland: Spinger Nature.

New developments in free fatty acids and lysophospholipids: decoding the role of phospholipases in exocytosis