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2019

Journal Article

Physical extraction and fast protein liquid chromatography for purifying flagella filament from uropathogenic Escherichia coli for immune assay

Acharya, Dhruba, Sullivan, Matthew J., Duell, Benjamin L., Eveno, Tanguy, Schembri, Mark A. and Ulett, Glen C. (2019). Physical extraction and fast protein liquid chromatography for purifying flagella filament from uropathogenic Escherichia coli for immune assay. Frontiers in Cellular and Infection Microbiology, 9 (APR) 118, 118. doi: 10.3389/fcimb.2019.00118

Physical extraction and fast protein liquid chromatography for purifying flagella filament from uropathogenic Escherichia coli for immune assay

2019

Journal Article

Uropathogenic Escherichia coli employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination

Stocks, Claudia J., Phan, Minh-Duy, Achard, Maud E. S., Nhu, Nguyen Thi Khanh, Condon, Nicholas D., Gawthorne, Jayde A., Lo, Alvin W., Peters, Kate M., McEwan, Alastair G., Kapetanovic, Ronan, Schembri, Mark A. and Sweet, Matthew J. (2019). Uropathogenic Escherichia coli employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination. Proceedings of the National Academy of Sciences, 116 (13), 6341-6350. doi: 10.1073/pnas.1820870116

Uropathogenic Escherichia coli employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination

2019

Journal Article

Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonization

Murthy, Ambika M. V., Sullivan, Matthew J., Nhu, Nguyen Thi Khanh, Lo, Alvin W., Phan, Minh-Duy, Peters, Kate M., Boucher, Dave, Schroder, Kate, Beatson, Scott A., Ulett, Glen C., Schembri, Mark A. and Sweet, Matthew J. (2019). Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonization. FASEB Journal : official publication of the Federation of American Societies for Experimental Biology, 33 (6), fj201802100R-7450. doi: 10.1096/fj.201802100R

Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonization

2019

Journal Article

Author correction: A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance (vol 8, 16065, 2017)

Furlong, Emily J., Lo, Alvin W., Kurth, Fabian, Premkumar, Lakshmanane, Totsika, Makrina, Achard, Maud E. S., Halili, Maria A., Heras, Begona, Whitten, Andrew E., Choudhury, Hassanul G., Schembri, Mark A. and Martin, Jennifer L. (2019). Author correction: A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance (vol 8, 16065, 2017). Nature Communications, 10 (1) 976, 976. doi: 10.1038/s41467-019-08920-9

Author correction: A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance (vol 8, 16065, 2017)

2019

Journal Article

A Retrospective Study Using the String of Pearls Tibial Plateau Levelling Osteotomy Locking Plate for the Treatment of Cranial Cruciate Ligament Disease

McGregor, Ross E., Buffa, Eugene A., Tan, Christopher J., Schembri, Mark A., Badcock, Caro-Anne and Lai, Alen (2019). A Retrospective Study Using the String of Pearls Tibial Plateau Levelling Osteotomy Locking Plate for the Treatment of Cranial Cruciate Ligament Disease. Veterinary and Comparative Orthopaedics and Traumatology, 32 (6), 483-491. doi: 10.1055/s-0039-1692189

A Retrospective Study Using the String of Pearls Tibial Plateau Levelling Osteotomy Locking Plate for the Treatment of Cranial Cruciate Ligament Disease

2018

Journal Article

Clay nanoparticles co-deliver three antigens to promote potent immune responses against pathogenic Escherichia coli

Chen, Weiyu, Zuo, Huali, Rolfe, Barbara, Schembri, Mark A., Cobbold, Rowland N., Zhang, Bing, Mahony, Timothy J. and Xu, Zhi Ping (2018). Clay nanoparticles co-deliver three antigens to promote potent immune responses against pathogenic Escherichia coli. Journal of Controlled Release, 292, 196-209. doi: 10.1016/j.jconrel.2018.11.008

Clay nanoparticles co-deliver three antigens to promote potent immune responses against pathogenic Escherichia coli

2018

Journal Article

Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance

Bohlmann, Lisa, De Oliveira, David M. P., El-Deeb, Ibrahim M., Brazel, Erin B., Harbison-Price, Nichaela, Ong, Cheryl-lynn Y., Rivera-Hernandez, Tania, Ferguson, Scott A., Cork, Amanda J., Phan, Minh-Duy, Soderholm, Amelia T., Davies, Mark R., Nimmo, Graeme R., Dougan, Gordon, Schembri, Mark A., Cook, Gregory M., McEwan, Alastair G., von Itzstein, Mark, McDevitt, Christopher A. and Walker, Mark J. (2018). Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance. mBio, 9 (6) e02391-18. doi: 10.1128/mbio.02391-18

Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance

2018

Journal Article

Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance

Bohlmann, Lisa, De Oliveira, David M. P., El-Deeb, Ibrahim M., Brazel, Erin B., Harbison-Price, Nichaela, Ong, Cheryl-lynn Y., Rivera-Hernandez, Tania, Ferguson, Scott A., Cork, Amanda J., Phan, Minh-Duy, Soderholm, Amelia T., Davies, Mark R., Nimmo, Graeme R., Dougan, Gordon, Schembri, Mark A., Cook, Gregory M., McEwan, Alastair G., von Itzstein, Mark, McDevitt, Christopher A. and Walker, Mark J. (2018). Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance. mBio, 9 (6) e02391-18, 1-12. doi: 10.1128/mBio.02391-18

Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance

2018

Journal Article

Discovery of mcr-1-mediated colistin resistance in a highly virulent Escherichia coli lineage

Forde, Brian M., Zowawi, Hosam M., Harris, Patrick N. A., Roberts, Leah, Ibrahim, Emad, Shaikh, Nissar, Deshmukh, Anand, Sid Ahmed, Mazen A., Al Maslamani, Muna, Cottrell, Kyra, Trembizki, Ella, Sundac, Lana, Yu, Heidi H., Li, Jian, Schembri, Mark A., Whiley, David M., Paterson, David L. and Beatson, Scott A. (2018). Discovery of mcr-1-mediated colistin resistance in a highly virulent Escherichia coli lineage. mSphere, 3 (5) e00486-18. doi: 10.1128/msphere.00486-18

Discovery of mcr-1-mediated colistin resistance in a highly virulent Escherichia coli lineage

2018

Journal Article

Discovery of new genes involved in curli production by a uropathogenic Escherichia coli strain from the highly virulent O45:K1:H7 lineage

Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Peters, Kate M., Lo, Alvin W., Forde, Brian M., Min Chong, Teik, Yin, Wai-Fong, Chan, Kok-Gan, Chromek, Milan, Brauner, Annelie, Chapman, Matthew R., Beatson, Scott A. and Schembri, Mark A. (2018). Discovery of new genes involved in curli production by a uropathogenic Escherichia coli strain from the highly virulent O45:K1:H7 lineage. mBio, 9 (4) e01462-18. doi: 10.1128/mbio.01462-18

Discovery of new genes involved in curli production by a uropathogenic Escherichia coli strain from the highly virulent O45:K1:H7 lineage

2018

Journal Article

Identification and characterization of a phase-variable element that regulates the autotransporter UpaE in uropathogenic Escherichia coli

Battaglioli, E. J., Goh, K. G. K., Atruktsang, T. S., Schwartz, K., Schembri, M. A. and Welch, R. A. (2018). Identification and characterization of a phase-variable element that regulates the autotransporter UpaE in uropathogenic Escherichia coli. mBio, 9 (4) e01360-18. doi: 10.1128/mbio.01360-18

Identification and characterization of a phase-variable element that regulates the autotransporter UpaE in uropathogenic Escherichia coli

2018

Journal Article

The urinary microbiome in patients with refractory urge incontinence and recurrent urinary tract infection

Chen, Zhuoran, Phan, Minh-Duy, Bates, Lucy J., Peters, Kate M., Mukerjee, Chinmoy, Moore, Kate H. and Schembri, Mark A. (2018). The urinary microbiome in patients with refractory urge incontinence and recurrent urinary tract infection. International Urogynecology Journal, 29 (12), 1-8. doi: 10.1007/s00192-018-3679-2

The urinary microbiome in patients with refractory urge incontinence and recurrent urinary tract infection

2018

Journal Article

A novel method of serum resistance by Escherichia coli that causes urosepsis

Coggon, Carrie F., Jiang, Andrew, Goh, Kelvin G. K., Henderson, Ian R., Schembri, Mark A. and Wells, Timothy J. (2018). A novel method of serum resistance by Escherichia coli that causes urosepsis. mBio, 9 (3) e00920-18, e00920-18. doi: 10.1128/mbio.00920-18

A novel method of serum resistance by Escherichia coli that causes urosepsis

2018

Journal Article

Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages

Murthy, Ambika M. V., Phan, Minh-Duy, Peters, Kate M., Nhu, Nguyen Thi Khanh, Welch, Rodney A., Ulett, Glen C., Schembri, Mark A. and Sweet, Matthew J. (2018). Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages. Virulence, 9 (1), 1-32. doi: 10.1080/21505594.2018.1465786

Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages

2018

Journal Article

Molecular basis for the folding of β-helical autotransporter passenger domains

Yuan, Xiaojun, Johnson, Matthew D., Zhang, Jing, Lo, Alvin W., Schembri, Mark A., Wijeyewickrema, Lakshmi C., Pike, Robert N., Huysmans, Gerard H. M., Henderson, Ian R. and Leyton, Denisse L. (2018). Molecular basis for the folding of β-helical autotransporter passenger domains. Nature Communications, 9 (1) 1395, 1395. doi: 10.1038/s41467-018-03593-2

Molecular basis for the folding of β-helical autotransporter passenger domains

2018

Journal Article

Intestinal colonization traits of pandemic multidrug-resistant Escherichia coli ST131

Sarkar, Sohinee, Hutton, Melanie L., Vagenas, Dimitrios, Ruter, Rinaldo, Schüller, Stephanie, Lyras, Dena, Schembri, Mark A. and Totsika, Makrina (2018). Intestinal colonization traits of pandemic multidrug-resistant Escherichia coli ST131. The Journal of Infectious Diseases, 218 (6), 979-990. doi: 10.1093/infdis/jiy031

Intestinal colonization traits of pandemic multidrug-resistant Escherichia coli ST131

2018

Journal Article

Copper ions and coordination complexes as novel carbapenem adjuvants

Djoko, Karrera Y., Achard, Maud E. S., Phan, Minh-Duy, Lo, Alvin W., Miraula, Manfredi, Prombhul, Sasiprapa, Hancock, Steven J., Peters, Kate M., Sidjabat, Hanna E., Harris, Patrick N., Mitić, Nataša, Walsh, Timothy R., Anderson, Gregory J., Shafer, William M., Paterson, David L., Schenk, Gerhard, McEwan, Alastair G. and Schembri, Mark A. (2018). Copper ions and coordination complexes as novel carbapenem adjuvants. Antimicrobial Agents and Chemotherapy, 62 (2) e02280-17. doi: 10.1128/AAC.02280-17

Copper ions and coordination complexes as novel carbapenem adjuvants

2018

Journal Article

Bacterial pathogenesis and interleukin-17: interconnecting mechanisms of immune regulation, host genetics, and microbial virulence that influence severity of infection

Chamoun, Michelle N., Blumenthal, Antje, Sullivan, Matthew J., Schembri, Mark A. and Ulett, Glen C. (2018). Bacterial pathogenesis and interleukin-17: interconnecting mechanisms of immune regulation, host genetics, and microbial virulence that influence severity of infection. Critical Reviews in Microbiology, 44 (4), 1-22. doi: 10.1080/1040841X.2018.1426556

Bacterial pathogenesis and interleukin-17: interconnecting mechanisms of immune regulation, host genetics, and microbial virulence that influence severity of infection

2018

Journal Article

For when bacterial infections persist: toll-like receptor-inducible direct antimicrobial pathways in macrophages

Stocks, Claudia J., Schembri, Mark A., Sweet, Matthew J. and Kapetanovic, Ronan (2018). For when bacterial infections persist: toll-like receptor-inducible direct antimicrobial pathways in macrophages. Journal of Leukocyte Biology, 103 (1), 35-51. doi: 10.1002/JLB.4RI0917-358R

For when bacterial infections persist: toll-like receptor-inducible direct antimicrobial pathways in macrophages

2017

Journal Article

Crystal structures of Staphylococcus aureus ketol-acid reductoisomerase in complex with two transition state analogs that have biocidal activity

Patel, Khushboo, Teran, David, Zheng, Shan, Kandale, Ajit, Garcia, Mario, Lv, You, Schembri, Mark A, McGeary, Ross P, Schenk, Gerhard and Guddat, Luke William (2017). Crystal structures of Staphylococcus aureus ketol-acid reductoisomerase in complex with two transition state analogs that have biocidal activity. Chemistry- A European Journal, 23 (72), 18289-18295. doi: 10.1002/chem.201704481

Crystal structures of Staphylococcus aureus ketol-acid reductoisomerase in complex with two transition state analogs that have biocidal activity