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2023 Journal Article Activity in the dorsomedial striatum underlies serial reversal learning performance under probabilistic uncertaintyYoung, Madison K., Conn, Kyna-Anne, Das, Joyosmita, Zou, Simin, Alexander, Suzy, Burne, Thomas H.J. and Kesby, James P. (2023). Activity in the dorsomedial striatum underlies serial reversal learning performance under probabilistic uncertainty. Biological Psychiatry Global Open Science, 3 (4), 1030-1041. doi: 10.1016/j.bpsgos.2022.08.005 |
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2022 Journal Article Impairments in goal-directed action and reversal learning in a proportion of individuals with psychosisSuetani, Shuichi, Baker, Andrea, Garner, Kelly, Cosgrove, Peter, Mackay-Sim, Matilda, Siskind, Dan, Murray, Graham K., Scott, James G. and Kesby, James P. (2022). Impairments in goal-directed action and reversal learning in a proportion of individuals with psychosis. Cognitive, Affective, and Behavioral Neuroscience, 22 (6), 1390-1403. doi: 10.3758/s13415-022-01026-8 |
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2021 Journal Article Neural circuitry of salience and reward processing in psychosisKesby, James P., Murray, Graham K. and Knolle, Franziska (2021). Neural circuitry of salience and reward processing in psychosis. Biological Psychiatry: Global Open Science, 3 (1), 33-46. doi: 10.1016/j.bpsgos.2021.12.003 |
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2020 Journal Article Subcortical dopamine and cognition in schizophrenia: looking beyond psychosis in preclinical modelsConn, Kyna-Anne, Burne, Thomas H. J. and Kesby, James P. (2020). Subcortical dopamine and cognition in schizophrenia: looking beyond psychosis in preclinical models. Frontiers in Neuroscience, 14 542, 542. doi: 10.3389/fnins.2020.00542 |
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2018 Journal Article Dopamine, psychosis and schizophrenia: the widening gap between basic and clinical neuroscienceKesby, J. P., Eyles, D. W., McGrath, J. J. and Scott, J. G. (2018). Dopamine, psychosis and schizophrenia: the widening gap between basic and clinical neuroscience. Translational Psychiatry, 8 (1) 30, 1-12. doi: 10.1038/s41398-017-0071-9 |
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2015 Journal Article Methamphetamine exposure combined with HIV-1 disease or gp120 expression: comparison of learning and executive functions in humans and miceKesby, James P., Heaton, Robert K., Young, Jared W., Umlauf, Anya, Woods, Steven P., Letendre, Scott L., Markou, Athina, Grant, Igor and Semenova, Svetlana (2015). Methamphetamine exposure combined with HIV-1 disease or gp120 expression: comparison of learning and executive functions in humans and mice. Neuropsychopharmacology, 40 (8), 1899-1909. doi: 10.1038/npp.2015.39 |
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2025 Journal Article Suppression of the dorsomedial striatum impairs reversal learning in response to probabilistic uncertainty and disrupts corticostriatal function in miceConn, Kyna-Anne, Das, Joyosmita, Alexander, Suzy, Burne, Thomas HJ. and Kesby, James P. (2025). Suppression of the dorsomedial striatum impairs reversal learning in response to probabilistic uncertainty and disrupts corticostriatal function in mice. Neuropharmacology, 278 110568, 110568-278. doi: 10.1016/j.neuropharm.2025.110568 |
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2025 Conference Publication Melatonin Mitigates IL-6-Induced Hyperdopaminergia, Oxidative Stress, and Metabolic Dysfunction: Implications for Dopaminergic Dysregulation in Bipolar DisorderMacpherson, Heather, Varela, Roger, Daygon, Venea, Kesby, James, Cui, Xiaoying and Tye, Susannah (2025). Melatonin Mitigates IL-6-Induced Hyperdopaminergia, Oxidative Stress, and Metabolic Dysfunction: Implications for Dopaminergic Dysregulation in Bipolar Disorder. HOBOKEN: WILEY. |
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2025 Journal Article Identification of conserved frontal neurophysiological markers of cognitive flexibility in humans and ratsDer-Avakian, Andre, Barnes, Samuel A., Lees, Ty, Schroder, Hans S., Kangas, Brian D., Linton, Samantha R., Nickels, Stefanie, Robble, Mykel A., Breiger, Micah, Iturra-Mena, Ann M., Lobien, Rachel, Perlo, Sarah, Cárdenas, Emilia F., Nowicki, Genevieve P., Wu, Zeyun, Pan, Hongyi, Dillon, Daniel G., Kesby, James P., Bergman, Jack, Carlezon, William A., Risbrough, Victoria B., Mukamel, Eran, Leutgeb, Stefan and Pizzagalli, Diego A. (2025). Identification of conserved frontal neurophysiological markers of cognitive flexibility in humans and rats. Communications Biology, 8 (1) 1268, 1268. doi: 10.1038/s42003-025-08729-x |
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2024 Journal Article The dynamic strategy shifting task: Optimisation of an operant task for assessing cognitive flexibility in ratsFlintoff, Jonathan Martin, Alexander, Suzy, Kesby, James Paul and Burne, Thomas Henry (2024). The dynamic strategy shifting task: Optimisation of an operant task for assessing cognitive flexibility in rats. Frontiers in Psychiatry, 15 1303728, 1-16. doi: 10.3389/fpsyt.2024.1303728 |
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2024 Journal Article The translational utility of circuit-based manipulations in preclinical modelsKesby, James P. and Turner, Karly M. (2024). The translational utility of circuit-based manipulations in preclinical models. Biological Psychiatry Global Open Science, 4 (1), 103-104. doi: 10.1016/j.bpsgos.2023.11.004 |
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2023 Journal Article Increasing dopamine synthesis in nigrostriatal circuits increases phasic dopamine release and alters dorsal striatal connectivity: implications for schizophreniaSrivastav, Sunil, Cui, Xiaoying, Varela, Roger Bitencourt, Kesby, James P. and Eyles, Darryl (2023). Increasing dopamine synthesis in nigrostriatal circuits increases phasic dopamine release and alters dorsal striatal connectivity: implications for schizophrenia. Schizophrenia, 9 (1) 69, 69. doi: 10.1038/s41537-023-00397-2 |
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2023 Journal Article Antagonism of D2 receptors via raclopride ameliorates amphetamine-induced associative learning deficits in male miceConn, Kyna-Anne, Alexander, Suzy, Burne, Thomas H.J. and Kesby, James P. (2023). Antagonism of D2 receptors via raclopride ameliorates amphetamine-induced associative learning deficits in male mice. Behavioural Brain Research, 454 114649, 114649. doi: 10.1016/j.bbr.2023.114649 |
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2023 Journal Article Reversal learning in those with early psychosis features contingency-dependent changes in loss response and learningBaker, Andrea, Suetani, Shuichi, Cosgrove, Peter, Siskind, Dan, Murray, Graham K., Scott, James G. and Kesby, James P. (2023). Reversal learning in those with early psychosis features contingency-dependent changes in loss response and learning. Cognitive Neuropsychiatry, 28 (5), 342-360. doi: 10.1080/13546805.2023.2259019 |
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2023 Journal Article Verbal and visual learning ability in patients with treatment-resistant schizophrenia: a 1-year follow-up studyArnautovska, Urska, Vitangcol, Kathryn, Kesby, James P., Warren, Nicola, Rossell, Susan L., Neill, Erica, Harris, Anthony, Galletly, Cherrie, Castle, David and Siskind, Dan (2023). Verbal and visual learning ability in patients with treatment-resistant schizophrenia: a 1-year follow-up study. Schizophrenia Research: Cognition, 33 100283, 100283. doi: 10.1016/j.scog.2023.100283 |
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2023 Journal Article Activating the dorsomedial and ventral midbrain projections to the striatum differentially impairs goal-directed action in male miceConn, Kyna-Anne, Zou, Simin, Das, Joyosmita, Alexander, Suzy, Burne, Thomas HJ. and Kesby, James P. (2023). Activating the dorsomedial and ventral midbrain projections to the striatum differentially impairs goal-directed action in male mice. Neuropharmacology, 234 109550, 109550. doi: 10.1016/j.neuropharm.2023.109550 |
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2022 Journal Article Biopsychology of physical activity in people with schizophrenia: an integrative perspective on barriers and intervention strategiesArnautovska, Urska, Kesby, James P, Korman, Nicole, Rebar, Amanda L., Chapman, Justin, Warren, Nicola, Rossell, Susan L., Dark, Frances L. and Siskind, Dan (2022). Biopsychology of physical activity in people with schizophrenia: an integrative perspective on barriers and intervention strategies. Neuropsychiatric Disease and Treatment, Volume 18, 2917-2926. doi: 10.2147/ndt.s393775 |
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2021 Journal Article Treating cognitive impairment in schizophrenia with GLP-1RAs: an overview of their therapeutic potentialFlintoff, Jonathan, Kesby, James P., Siskind, Dan and Burne, Thomas H. J. (2021). Treating cognitive impairment in schizophrenia with GLP-1RAs: an overview of their therapeutic potential. Expert Opinion on Investigational Drugs, 30 (8), 877-891. doi: 10.1080/13543784.2021.1951702 |
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2021 Journal Article Developmental inhibition of long intergenic non-coding RNA, HOTAIRM1, impairs dopamine neuron differentiation and maturationCui, Xiaoying, Pertile, Renata Ap. Nedel, Du, Zilong, Wei, Wei, Sun, Zichun, Eyles, Darryl W. and Kesby, James P. (2021). Developmental inhibition of long intergenic non-coding RNA, HOTAIRM1, impairs dopamine neuron differentiation and maturation. International Journal of Molecular Sciences, 22 (14) 7268, 7268. doi: 10.3390/ijms22147268 |
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2021 Journal Article Positive symptom phenotypes appear progressively in “EDiPS”, a new animal model of the schizophrenia prodromePetty, Alice, Cui, Xiaoying, Ali, Asad, Du, Zilong, Srivastav, Sunil, Kesby, James P., Kirik, Deniz, Howes, Oliver and Eyles, Darryl (2021). Positive symptom phenotypes appear progressively in “EDiPS”, a new animal model of the schizophrenia prodrome. Scientific Reports, 11 (1) 4294, 4294. doi: 10.1038/s41598-021-83681-4 |
