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2024

Conference Publication

Trastuzumab-Induced Cardiotoxicity Involves Antibody Dependent Cell Cytotoxicity (ADCC)

Griffiths, L., Ho, U., Burt, K., Watson, S., Patel, K., Bradford, J., Tan, C., Bhavsar, C., Palpant, N., Souza-Fonseca-Guimaraes, F., Wu, S., Reichelt, M. and Thomas, W. (2024). Trastuzumab-Induced Cardiotoxicity Involves Antibody Dependent Cell Cytotoxicity (ADCC). 72nd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Perth, WA Australia, 1-4 August 2024. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2024.06.397

Trastuzumab-Induced Cardiotoxicity Involves Antibody Dependent Cell Cytotoxicity (ADCC)

2024

Conference Publication

Targeting Cardiomyocytes with Adeno Associated Viruses to Protect Hearts from Trastuzumab-induced Cardiotoxicity

Reichelt, Melissa, Ho, Uda, Bunt, Kelsey, Watson, Sophie, Patel, Kinjal, Bradford, Julia and Thomas, Walter G. (2024). Targeting Cardiomyocytes with Adeno Associated Viruses to Protect Hearts from Trastuzumab-induced Cardiotoxicity. American Physiology Summit 2024, Long Beach, CA United States, 4-7 April 2024. Rockville, MD United States: American Physiological Society. doi: 10.1152/physiol.2024.39.s1.2480

Targeting Cardiomyocytes with Adeno Associated Viruses to Protect Hearts from Trastuzumab-induced Cardiotoxicity

2022

Journal Article

RNA metabolism and links to inflammatory regulation and disease

Lai, Hui-Chi, Ho, Uda Y., James, Alexander, De Souza, Paul and Roberts, Tara L. (2022). RNA metabolism and links to inflammatory regulation and disease. Cellular and Molecular Life Sciences, 79 (1) 21, 21. doi: 10.1007/s00018-021-04073-5

RNA metabolism and links to inflammatory regulation and disease

2021

Journal Article

Cilia, centrosomes and skeletal muscle

Ng, Dominic C. H., Ho, Uda Y. and Grounds, Miranda D. (2021). Cilia, centrosomes and skeletal muscle. International Journal of Molecular Sciences, 22 (17) 9605, 9605. doi: 10.3390/ijms22179605

Cilia, centrosomes and skeletal muscle

2021

Journal Article

WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis

Ho, Uda Y., Feng, Chun-Wei Allen, Yeap, Yvonne Y., Bain, Amanda L., Wei, Zhe, Shohayeb, Belal, Reichelt, Melissa E., Homer, Hayden, Khanna, Kum Kum, Bowles, Josephine and Ng, Dominic C. H. (2021). WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis. Communications Biology, 4 (1) 645, 1-14. doi: 10.1038/s42003-021-02171-5

WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis

2020

Journal Article

Centrosome reduction promotes terminal differentiation of human cardiomyocytes

Ng, Dominic C.H., Richards, Dominic K., Mills, Richard J., Ho, Uda Y., Perks, Hannah L., Tucker, Callum R., Voges, Holly K., Pagan, Julia K. and Hudson, James E. (2020). Centrosome reduction promotes terminal differentiation of human cardiomyocytes. Stem Cell Reports, 15 (4), 817-826. doi: 10.1016/j.stemcr.2020.08.007

Centrosome reduction promotes terminal differentiation of human cardiomyocytes

2020

Journal Article

The spindle-associated microcephaly protein, WDR62, is required for neurogenesis and development of the hippocampus

Shohayeb, Belal, Ho, Uda Y., Hassan, Halah, Piper, Michael and Ng, Dominic C. H. (2020). The spindle-associated microcephaly protein, WDR62, is required for neurogenesis and development of the hippocampus. Frontiers in Cell and Developmental Biology, 8 549353, 549353. doi: 10.3389/fcell.2020.549353

The spindle-associated microcephaly protein, WDR62, is required for neurogenesis and development of the hippocampus

2020

Journal Article

Regulation of RNA degradation pathways during the lipopolysaccharide response in macrophages

Lai, Hui-Chi, James, Alexander, Luff, John, De Souza, Paul, Quek, Hazel, Ho, Uda, Lavin, Martin F. and Roberts, Tara L. (2020). Regulation of RNA degradation pathways during the lipopolysaccharide response in macrophages. Journal of Leukocyte Biology, 109 (3) JLB.2AB0420-151RR, 593-603. doi: 10.1002/JLB.2AB0420-151RR

Regulation of RNA degradation pathways during the lipopolysaccharide response in macrophages

2020

Journal Article

Arp2/3 nucleates F-actin coating of fusing insulin granules in pancreatic β cells to control insulin secretion

Ma, Wei, Chang, Jenny, Tong, Jason, Ho, Uda, Yau, Belinda, Kebede, Melkam A. and Thorn, Peter (2020). Arp2/3 nucleates F-actin coating of fusing insulin granules in pancreatic β cells to control insulin secretion. Journal of Cell Science, 133 (6) jcs236794. doi: 10.1242/jcs.236794

Arp2/3 nucleates F-actin coating of fusing insulin granules in pancreatic β cells to control insulin secretion

2020

Journal Article

The association of microcephaly protein WDR62 with CPAP/IFT88 is required for cilia formation and neocortical development

Shohayeb, Belal, Ho, Uda, Yeap, Yvonne Y., Parton, Robert G., Millard, Sean S., Xu, Zhiheng, Piper, Michael and Ng, Dominic C. H. (2020). The association of microcephaly protein WDR62 with CPAP/IFT88 is required for cilia formation and neocortical development. Human Molecular Genetics, 29 (2), 248-263. doi: 10.1093/hmg/ddz281

The association of microcephaly protein WDR62 with CPAP/IFT88 is required for cilia formation and neocortical development

2019

Journal Article

SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress

Ho, Uda, Luff, John, James, Alexander, Lee, Cheok Soon, Quek, Hazel, Lai, Hui-Chi, Apte, Simon, Lim, Yi Chieh, Lavin, Martin F. and Roberts, Tara L. (2019). SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress. Journal of Cellular and Molecular Medicine, 23 (12) jcmm.14685, 8151-8160. doi: 10.1111/jcmm.14685

SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress

2017

Journal Article

Patched1 patterns fibroblast growth factor 10 and forkhead box F1 expression during pulmonary branch formation

Ho, Uda Y. and Wainwright, Brandon J. (2017). Patched1 patterns fibroblast growth factor 10 and forkhead box F1 expression during pulmonary branch formation. Mechanisms of Development, 147, 37-48. doi: 10.1016/j.mod.2017.09.001

Patched1 patterns fibroblast growth factor 10 and forkhead box F1 expression during pulmonary branch formation

2017

Journal Article

The Role of WD40-Repeat Protein 62 (MCPH2) in Brain Growth: Diverse Molecular and Cellular Mechanisms Required for Cortical Development

Shohayeb, Belal, Lim, Nicholas Rui, Ho, Uda, Xu, Zhiheng, Dottori, Mirella, Quinn, Leonie and Ng, Dominic Chi Hiung (2017). The Role of WD40-Repeat Protein 62 (MCPH2) in Brain Growth: Diverse Molecular and Cellular Mechanisms Required for Cortical Development. Molecular Neurobiology, 55 (7), 5409-5424. doi: 10.1007/s12035-017-0778-x

The Role of WD40-Repeat Protein 62 (MCPH2) in Brain Growth: Diverse Molecular and Cellular Mechanisms Required for Cortical Development

2016

Conference Publication

SMG1 is a regulator of toll-like receptor responses

James, A., Luff, J., Ho, U., Quek, H., Lavin, M. and Roberts, T. (2016). SMG1 is a regulator of toll-like receptor responses. International Congress of Immunology (ICI), Melbourne, Australia, 21-26 August 2016.

SMG1 is a regulator of toll-like receptor responses

2015

Conference Publication

ATM and SMG1 are tumour suppressors which co- regulate blood cancer development and cellular responses to DNA damage and oxidative stress

Reberio, Patricia, James, Alexander, Ling, Silvia, Lee, C. Soon, Ho, Uda, Luff, John, Quek, Hazel, Lavin, Martin and Roberts, Tara (2015). ATM and SMG1 are tumour suppressors which co- regulate blood cancer development and cellular responses to DNA damage and oxidative stress. XVI International Workshop on ChronicLymphocytic Leukemia 2015, Sydney, Australia, 6–9 September 2015. United Kingdom: Taylor & Francis. doi: 10.3109/10428194.2015.1080893

ATM and SMG1 are tumour suppressors which co- regulate blood cancer development and cellular responses to DNA damage and oxidative stress

2015

Conference Publication

The roles of SMG1 and ATM in stress responses, inflammation and blood cancers

Roberts, Tara L., Ho, Uda, Luff, John, James, Alex, Apte, Simon, Quek, Hazel and Lavin, Martin F. (2015). The roles of SMG1 and ATM in stress responses, inflammation and blood cancers. *, *, *. ATHENS: SPANDIDOS PUBL LTD.

The roles of SMG1 and ATM in stress responses, inflammation and blood cancers

2014

Journal Article

Functional genomics identified a novel protein tyrosine phosphatase receptor type f-mediated growth inhibition in hepatocarcinogenesis

Bera, Rabindranath, Chiou, Chih-Yung, Yu, Ming-Chin, Peng, Jei-Ming, He, Chung-Ru, Hsu, Chih-Yun, Huang, Hsiao-Ling, Ho, Uda Y., Lin, Shi-Ming, Lin, Yu-Jr and Hsieh, Sen-Yung (2014). Functional genomics identified a novel protein tyrosine phosphatase receptor type f-mediated growth inhibition in hepatocarcinogenesis. Hepatology, 59 (6), 2238-2250. doi: 10.1002/hep.27030

Functional genomics identified a novel protein tyrosine phosphatase receptor type f-mediated growth inhibition in hepatocarcinogenesis

2013

Journal Article

Essential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2

Shi, Wei, Bain, Amanda L., Schwer, Bjoern, Al-Ejeh, Fares, Smith, Corey, Wong, Lee, Chai, Hua, Miranda, Mariska S., Ho, Uda, Kawaguchi, Makoto, Miura, Yutaka, Finnie, John W., Wall, Meaghan, Heierhorst, Jorg, Wicking, Carol, Spring, Kevin J., Alt, Frederick W. and Khanna, Kum Kum (2013). Essential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2. PLoS Genetics, 9 (2) e1003298, e1003298.1-e1003298.19. doi: 10.1371/journal.pgen.1003298

Essential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2

2013

Journal Article

Smg1 haploinsufficiency predisposes to tumor formation and inflammation

Roberts, Tara L., Ho, Uda, Luff, John, Lee, C. Soon, Apte, Simon H., MacDonald, Kelli P. A., Raggatt, Liza-Jane, Pettit, Allison R., Morrow, Carl A., Waters, Michael J., Chen, Phil, Woods, Rick G., Thomas, Gethin P., St. Pierre, Liam, Farah, Camile S., Clarke, Raymond A., Brown, James A. L. and Lavin, Martin F. (2013). Smg1 haploinsufficiency predisposes to tumor formation and inflammation. PNAS: Proceedings of the National Academy of Sciences of the United States of America, 110 (4), E285-E294. doi: 10.1073/pnas.1215696110

Smg1 haploinsufficiency predisposes to tumor formation and inflammation

2010

Other Outputs

Hedgehog signalling in lung development and airway regeneration

Ho, Uda (2010). Hedgehog signalling in lung development and airway regeneration. PhD Thesis, Institute for Molecular Bioscience, The University of Queensland.

Hedgehog signalling in lung development and airway regeneration