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2011 Journal Article Breast cancer stem cells: Treatment resistance and therapeutic opportunitiesAL-Ejeh, Fares, Smart, Chanel E., Morrison, Brian J., Chenevix-Trench, Georgia, Lopez, J. Alejandro, Lakhani, Sunil R., Brown, Michael P. and Khanna, Kum Kum (2011). Breast cancer stem cells: Treatment resistance and therapeutic opportunities. Carcinogenesis, 32 (5), 650-658. doi: 10.1093/carcin/bgr028 |
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2011 Journal Article SNORD-host RNA Zfas1 is a regulator of mammary development and a potential marker for breast cancerAskarian-Amiri, Marjan E., Crawford, Joanna, French, Juliet D., Smart, Chanel E., Smith, Martin A., Clark, Michael B., Ru, Kelin, Mercer, Tim R., Thompson, Ella R., Lakhani, Sunil R., Vargas, Ana C., Campbell, Ian G., Brown, Melissa A., Dinger, Marcel E. and Mattick, John S. (2011). SNORD-host RNA Zfas1 is a regulator of mammary development and a potential marker for breast cancer. RNA, 17 (5), 878-891. doi: 10.1261/rna.2528811 |
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2011 Journal Article Phenotype-genotype correlation in familial breast cancerVargas, A.C., Reis, J.S. and Lakhani, S.R. (2011). Phenotype-genotype correlation in familial breast cancer. Journal of Mammary Gland Biology and Neoplasia, 16 (1), 27-40. doi: 10.1007/s10911-011-9204-6 |
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2011 Journal Article Analysis of brca1-deficient mouse mammary glands reveals reciprocal regulation of Brca1 and c-kitSmart, C.E., Wronski, A., French, J.D., Edwards, S.L., Asselin-Labat, M.L., Waddell, N., Peters, K., Brewster, B.L., Brooks, K., Simpson, K., Manning, N., Lakhani, S.R., Grimmond, S., Lindeman, G.J., Visvader, J.E. and Brown, M.A. (2011). Analysis of brca1-deficient mouse mammary glands reveals reciprocal regulation of Brca1 and c-kit. Oncogene, 30 (13), 1597-1607. doi: 10.1038/onc.2010.538 |
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2011 Journal Article Basal-like and triple-negative breast cancers: A critical review with an emphasis on the implications for pathologists and oncologistsBadve, Sunil, Dabbs, David J., Schnitt, Stuart J., Baehner, Frederick L., Decker, Thomas, Eusebi, Vincenzo, Fox, Stephen B., Ichihara, Shu, Jacquemier, Jocelyne, Lakhani, Sunil R., Palacios, Jose, Rakha, Emad A., Richardson, Andrea L., Schmitt, Fernando C., Tan, Puay-Hoon, Tse, Gary M., Weigelt, Britta, Ellis, Ian O. and Reis-Filho, Jorge S. (2011). Basal-like and triple-negative breast cancers: A critical review with an emphasis on the implications for pathologists and oncologists. Modern Pathology, 24 (2), 157-167. doi: 10.1038/modpathol.2010.200 |
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2011 Journal Article Application of molecular findings to the diagnosis and management of breast disease: Recent advances and challengesSimpson, Peter T., Vargas, Ana Christina, Al-Ejeh, Fares, Khanna, Kum Kum, Chenevix-Trench, Georgia and Lakhani, Sunil R. (2011). Application of molecular findings to the diagnosis and management of breast disease: Recent advances and challenges. Human Pathology, 42 (2), 153-165. doi: 10.1016/j.humpath.2010.07.008 |
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2011 Journal Article Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriersRamus, Susan J., Kartsonaki, Christiana, Gayther, Simon A., Pharoah, Paul D. P., Sinilnikova, Olga M., Beesley, Jonathan, Chen, Xiaoqing, McGuffog, Lesley, Healey, Sue, Couch, Fergus J., Wang, Xianshu, Fredericksen, Zachary, Peterlongo, Paolo, Manoukian, Siranoush, Peissel, Bernard, Zaffaroni, Daniela, Roversi, Gaia, Barile, Monica, Viel, Alessandra, Allavena, Anna, Ottini, Laura, Papi, Laura, Gismondi, Viviana, Capra, Fabio, Radice, Paolo, Greene, Mark H., Mai, Phuong L., Andrulis, Irene L., Glendon, Gord ... Lakhani, Sunil (2011). Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers. Journal of the National Cancer Institiute, 103 (2), 105-116. doi: 10.1093/jnci/djq494 |
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2011 Journal Article Molecular aspects of breast cancer metastasis to the brainSaunus, Jodi M., Momeny, Majid, Simpson, Peter T., Da Silva, Leonard and Lakhani, Sunil R. (2011). Molecular aspects of breast cancer metastasis to the brain. Genetics Research International, 2011, 219189-1-219189-9. doi: 10.4061/2011/219189 |
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2011 Journal Article Molecular classification of breast cancer: Is it time to pack up our microscopes?Cummings, Margaret C., Chambers, Rachael, Simpson, Peter T. and Lakhani, Sunil R. (2011). Molecular classification of breast cancer: Is it time to pack up our microscopes?. Pathology, 43 (1), 1-8. doi: 10.1097/PAT.0b013e328341e0b5 |
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2010 Journal Article The contribution of breast cancer pathology to statistical models to predict mutation risk in BRCA carriersVargas, AC, Da Silva, L and Lakhani, SR (2010). The contribution of breast cancer pathology to statistical models to predict mutation risk in BRCA carriers. Familial Cancer, 9 (4), 545-553. doi: 10.1007/s10689-010-9362-5 |
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2010 Journal Article Harnessing the complexity of DNA-damage response pathways to improve cancer treatment outcomesAl-Ejeh, F., Kumar, R., Wiegmans, A., Lakhani, S.R., Brown, M.P. and Khanna, K.K. (2010). Harnessing the complexity of DNA-damage response pathways to improve cancer treatment outcomes. Oncogene, 29 (46), 6085-6098. doi: 10.1038/onc.2010.407 |
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2010 Journal Article DNA methylation profiling of phyllodes and fibroadenoma tumours of the breastHuang, Katie T., Dobrovic, Alexander, Yan, Max, Karim, Rooshdiya Z., Lee, C. Soon, Lakhani, Sunil R. and Fox, Stephen B. (2010). DNA methylation profiling of phyllodes and fibroadenoma tumours of the breast. Breast Cancer Research and Treatment, 124 (2), 555-565. doi: 10.1007/s10549-010-0970-4 |
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2010 Journal Article A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general populationAntoniou, Antonis C., Wang, Xianshu, Fredericksen, Zachary S., McGuffog, Lesley, Tarrell, Robert, Sinilnikova, Olga M., Healey, Sue, Morrison, Jonathan, Kartsonaki,Christiana, Lesnick, Timothy, Ghoussaini, Maya, Barrowdale, Daniel, Peock, Susan, Cook, Margaret, Oliver, Clare, Frost, Debra, Eccles, Diana, Evans, D. Gareth, Eeles, Ros, Izatt, Louise, Chu, Carol, Douglas, Fiona, Paterson, Joan, Stoppa-Lyonnet, Dominique, Houdayer, Claude, Mazoyer, Sylvie, Giraud, Sophie, Lasset, Christine, Remenieras, Audrey ... Lakhani, Sunil (2010). A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population. Nature Genetics, 42 (10), 885-892. doi: 10.1038/ng.669 |
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2010 Journal Article Common genetic variants and modification of penetrance of BRCA2-associated breast cancerMia M. Gaudet, Tomas Kirchhoff, Todd Green, Joseph Vijai, Joshua M. Korn, Candace Guiducci, Ayellet V. Segre, Kate McGee, Lesley McGuffog, Christiana Kartsonaki, Jonathan Morrison, Sue Healey, Olga M. Sinilnikova, Dominique Stoppa-Lyonnet, Sylvie Mazoyer, Marion Gauthier-Villars, Hagay Sobol, Michel Longy, Marc Frenay, GEMO Study Collaborators, Frans B. L. Hogervorst, Matti a. Rookus, J. Margriet Collee, Nicoline Hoogerbrugge, Kees E. P. van Roozendaal, HEBON Study Collaborators, Marion Piedmonte, Wendy Rubinstein, Stacy Nerenstone ... Lakhani, Sunil (2010). Common genetic variants and modification of penetrance of BRCA2-associated breast cancer. PLoS Genetics, 6 (10), e1001183-1-e1001183-12. doi: 10.1371/journal.pgen.1001183 |
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2010 Journal Article Subtypes of familial breast tumours revealed by expression and copy number profilingWaddell, N, Arnold, J, Cocciardi, S, da Silva, L, Marsh, A, Riley, J, Johnstone, CN, Orloff, M, Assie, G, Eng, C, Reid, L, Keith, P, Yan, M, Fox, S, Devilee, P, Godwin, AK, Hogervorst, FBL, Couch, F, Grimmond, S, Flanagan, JM, Khanna, K, Simpson, PT, Lakhani, SR, Chenevix-Trench, G and kConFab Investigators (2010). Subtypes of familial breast tumours revealed by expression and copy number profiling. Breast Cancer Research And Treatment, 123 (3), 661-677. doi: 10.1007/s10549-009-0653-1 |
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2010 Journal Article Gene expression profiling of formalin-fixed, paraffin-embedded familial breast tumours using the whole genome-DASL assayWaddell, Nic, Cocciardi, Sibylle, Johnson, Julie, Healey, Sue, Marsh, Anna, Riley, Joan, da Silva, Leonard, Vargas, Ana Cristina, Reid, Lynne, Simpson, Peter T., Lakhani, Sunil R. and Chenevix-Trench, Georgia (2010). Gene expression profiling of formalin-fixed, paraffin-embedded familial breast tumours using the whole genome-DASL assay. Journal of Pathology, 221 (4), 452-461. doi: 10.1002/path.2728 |
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2010 Journal Article Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriersWang, Xianshu, Pankratz, V. Shane, Fredericksen, Zachary, Tarrell, Robert, Karaus, Mary, McGuffog, Lesley, Pharaoh, Paul D.P., Ponder, Bruce A.J., Dunning, Alison M., Peock, Susan, Cook, Margaret, Oliver, Clare, Frost, Debra, EMBRACE, Sinilnikova, Olga M., Stoppa-Lyonnet, Dominique, Mazoyer, Sylvie, Houdayer, Claude, GEMO, Hogervorst, Frans B.L., Hooning, Maartje J., Ligtenberg, Marjolijn J., HEBON, Spurdle, Amanda, Chenevix-Trench, Georgia, kConFab, Schmutzler, Rita K., Wappenschmidt, Barbara, Engel, Christoph ... Lakhani, Sunil (2010). Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers. Human Molecular Genetics, 19 (14), 2886-2897. doi: 10.1093/hmg/ddq174 |
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2010 Journal Article Dissecting the transcriptional networks underlying breast cancer: NR4A1 reduces the migration of normal and breast cancer cell linesAlexopoulou, Annika N., Leao, Maria, Caballero, Otavia L., Da Silva, Leonard, Reid, Lynne, Lakhani, Sunil R., Simpson, Andrew J., Marshall, John F., Neville, A. Munro and Jat, Parmjit S. (2010). Dissecting the transcriptional networks underlying breast cancer: NR4A1 reduces the migration of normal and breast cancer cell lines. Breast Cancer Research, 12 (4) R51, R51-1-R51-17. doi: 10.1186/bcr2610 |
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2010 Journal Article Detection of Splicing Aberrations Caused by BRCA1 and BRCA2 Sequence Variants Encoding Missense Substitutions: Implications for Prediction of PathogenicityWalker, Logan C., Whiley, Phillip J., Couch, Fergus J., Farrugia, Daniel J., Healey, Sue, Eccles, Diana M., Lin, Feng, Butler, Samantha A., Goff, Sheila A., Thompson, Bryony A., Lakhani, Sunil R., Da Silva, Leonard M., Tavtigian, Sean V., Goldgar, David E., Brown, Melissa A. and Spurdle, Amanda B. (2010). Detection of Splicing Aberrations Caused by BRCA1 and BRCA2 Sequence Variants Encoding Missense Substitutions: Implications for Prediction of Pathogenicity. Human Mutation, 31 (6), E1484-E1505. doi: 10.1002/humu.21267 |
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2010 Journal Article Incorporating tumour pathology information into breast cancer risk prediction algorithmsMavaddat, Nasim, Rebbeck, Timothy R., Lakhani, Sunil R., Easton, Douglas F. and Antoniou, Antonis C. (2010). Incorporating tumour pathology information into breast cancer risk prediction algorithms. Breast Cancer Research, 12 (3) R28, R28 - 1-R28 - 12. doi: 10.1186/bcr2576 |
