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2022

Journal Article

Prospective optimization of endobronchial ultrasound-guided transbronchial needle aspiration lymph node assessment for lung cancer: Three needle agitations are noninferior to 10 agitations for adequate tumor cell and DNA yield

Fielding, David, Dalley, Andrew J., Singh, Mahendra, Nandakumar, Lakshmy, Nones, Katia, Lakis, Vanessa, Chittoory, Haarika, Ferguson, Kaltin, Bashirzadeh, Farzad, Bint, Michael, Pahoff, Carl, Son, Jung Hwa, Hodgson, Alan, Sharma, Sowmya, Godbolt, David, Coleman, Kylie, Whitfield, Lenore, Waddell, Nicola, Lakhani, Sunil R., Hartel, Gunter and Simpson, Peter T. (2022). Prospective optimization of endobronchial ultrasound-guided transbronchial needle aspiration lymph node assessment for lung cancer: Three needle agitations are noninferior to 10 agitations for adequate tumor cell and DNA yield. JTO Clinical and Research Reports, 3 (10) 100403, 100403. doi: 10.1016/j.jtocrr.2022.100403

Prospective optimization of endobronchial ultrasound-guided transbronchial needle aspiration lymph node assessment for lung cancer: Three needle agitations are noninferior to 10 agitations for adequate tumor cell and DNA yield

2022

Journal Article

Modeling brain metastasis by internal carotid artery injection of cancer cells

Lim, Malcolm, Fletcher, Nicholas, Reed, Amy Mccart, Flint, Melanie, Thurecht, Kristofer, Saunus, Jodi and Lakhani, Sunil R. (2022). Modeling brain metastasis by internal carotid artery injection of cancer cells. Journal of Visualized Experiments, 2022 (186) e64216. doi: 10.3791/64216

Modeling brain metastasis by internal carotid artery injection of cancer cells

2022

Journal Article

The increasing importance of pathology in modern clinical trial conduct: OlympiA as a case in point

Kalinowski, Lauren, Viale, Giuseppe, Domchek, Susan, Tutt, Andrew, Lucas, Peter C. and Lakhani, Sunil R. (2022). The increasing importance of pathology in modern clinical trial conduct: OlympiA as a case in point. Pathology, 54 (5), 511-516. doi: 10.1016/j.pathol.2022.05.003

The increasing importance of pathology in modern clinical trial conduct: OlympiA as a case in point

2022

Journal Article

Epigenome erosion and SOX10 drive neural crest phenotypic mimicry in triple-negative breast cancer

Saunus, Jodi M., De Luca, Xavier M., Northwood, Korinne, Raghavendra, Ashwini, Hasson, Alexander, McCart Reed, Amy E., Lim, Malcolm, Lal, Samir, Vargas, A. Cristina, Kutasovic, Jamie R., Dalley, Andrew J., Miranda, Mariska, Kalaw, Emarene, Kalita-de Croft, Priyakshi, Gresshoff, Irma, Al-Ejeh, Fares, Gee, Julia M. W., Ormandy, Chris, Khanna, Kum Kum, Beesley, Jonathan, Chenevix-Trench, Georgia, Green, Andrew R., Rakha, Emad A., Ellis, Ian O., Nicolau, Dan V., Simpson, Peter T. and Lakhani, Sunil R. (2022). Epigenome erosion and SOX10 drive neural crest phenotypic mimicry in triple-negative breast cancer. npj Breast Cancer, 8 (1) 57, 1-16. doi: 10.1038/s41523-022-00425-x

Epigenome erosion and SOX10 drive neural crest phenotypic mimicry in triple-negative breast cancer

2022

Journal Article

N-glycolylneuraminic acid serum biomarker levels are elevated in breast cancer patients at all stages of disease

Shewell, Lucy K., Day, Christopher J., Kutasovic, Jamie R., Abrahams, Jodie L., Wang, Jing, Poole, Jessica, Niland, Colleen, Ferguson, Kaltin, Saunus, Jodi M., Lakhani, Sunil R., von Itzstein, Mark, Paton, James C., Paton, Adrienne W. and Jennings, Michael P. (2022). N-glycolylneuraminic acid serum biomarker levels are elevated in breast cancer patients at all stages of disease. BMC Cancer, 22 (1) 334, 334. doi: 10.1186/s12885-022-09428-0

N-glycolylneuraminic acid serum biomarker levels are elevated in breast cancer patients at all stages of disease

2022

Journal Article

Emerging biomarkers for diagnosis, prevention and treatment of brain metastases—from biology to clinical utility

Kalita-de Croft, Priyakshi, Joshi, Vaibhavi, Saunus, Jodi M. and Lakhani, Sunil R. (2022). Emerging biomarkers for diagnosis, prevention and treatment of brain metastases—from biology to clinical utility. Diseases, 10 (1) 11, 1-14. doi: 10.3390/diseases10010011

Emerging biomarkers for diagnosis, prevention and treatment of brain metastases—from biology to clinical utility

2022

Journal Article

Landscape of epidermal growth factor receptor heterodimers in brain metastases

Lim, Malcolm, Nguyen, Tam H., Niland, Colleen, Reid, Lynne E., Jat, Parmjit S., Saunus, Jodi M. and Lakhani, Sunil R. (2022). Landscape of epidermal growth factor receptor heterodimers in brain metastases. Cancers, 14 (3) 533, 533. doi: 10.3390/cancers14030533

Landscape of epidermal growth factor receptor heterodimers in brain metastases

2022

Journal Article

Whole genome deep sequencing analysis of cell-free DNA in samples with low tumour content

Ganesamoorthy, Devika, Robertson, Alan James, Chen, Wenhan, Hall, Michael B., Cao, Minh Duc, Ferguson, Kaltin, Lakhani, Sunil R., Nones, Katia, Simpson, Peter T. and Coin, Lachlan J. M. (2022). Whole genome deep sequencing analysis of cell-free DNA in samples with low tumour content. BMC Cancer, 22 (1) 85, 85. doi: 10.1186/s12885-021-09160-1

Whole genome deep sequencing analysis of cell-free DNA in samples with low tumour content

2022

Journal Article

Blood-derived extracellular vesicle-associated miR-3182 detects non-small cell lung cancer patients

Visan, Kekoolani S., Lobb, Richard J., Wen, Shu Wen, Bedo, Justin, Lima, Luize G., Krumeich, Sophie, Palma, Carlos, Ferguson, Kaltin, Green, Ben, Niland, Colleen, Cloonan, Nicole, Simpson, Peter T., McCart Reed, Amy E., Everitt, Sarah J., MacManus, Michael P., Hartel, Gunter, Salomon, Carlos, Lakhani, Sunil R., Fielding, David and Möller, Andreas (2022). Blood-derived extracellular vesicle-associated miR-3182 detects non-small cell lung cancer patients. Cancers, 14 (1) 257, 257. doi: 10.3390/cancers14010257

Blood-derived extracellular vesicle-associated miR-3182 detects non-small cell lung cancer patients

2022

Book Chapter

Future role of molecular profiling in small breast samples and personalised medicine

Foong, Samuel Y. F., Simpson, Peter T., Cummings, Margaret C. and Lakhani, Sunil R. (2022). Future role of molecular profiling in small breast samples and personalised medicine. A comprehensive guide to core needle biopsies of the breast. (pp. 895-915) edited by Sandra J. Shin, Yunn-Yi Chen and Paula S. Ginter. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-031-05532-4_23

Future role of molecular profiling in small breast samples and personalised medicine

2021

Journal Article

The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group

El Bairi, Khalid, Haynes, Harry R., Blackley, Elizabeth, Fineberg, Susan, Shear, Jeffrey, Turner, Sophia, de Freitas, Juliana Ribeiro, Sur, Daniel, Amendola, Luis Claudio, Gharib, Masoumeh, Kallala, Amine, Arun, Indu, Azmoudeh-Ardalan, Farid, Fujimoto, Luciana, Sua, Luz F., Liu, Shi-Wei, Lien, Huang-Chun, Kirtani, Pawan, Balancin, Marcelo, El Attar, Hicham, Guleria, Prerna, Yang, Wenxian, Shash, Emad, Chen, I-Chun, Bautista, Veronica, Do Prado Moura, Jose Fernando, Rapoport, Bernardo L., Castaneda, Carlos, Spengler, Eunice ... The International Immuno-Oncology Biomarker Working Group (2021). The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group. npj Breast Cancer, 7 (1) 150. doi: 10.1038/s41523-021-00346-1

The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group

2021

Conference Publication

Implementation of precision oncology for breast cancer care in Brisbane: Q-IMPROvE

McCart Reed, Amy, McCurry, Therese, Simpson, Peter, Inglis, Po-Ling, Ung, Owen, Murugappan, Kowsalya, Waddell, Nic, Snell, Cameron, Woodward, Natasha, Middleton, Kathryn, Walpole, Euan, O'Byrne, Ken, Cuff, Katharine, Andelkovic, Vladimir, Roberts, Kate, Steinke, Karin, Santamaria, Gorane, McCarthy, Nicole, Mar Fan, Helen, Kalinowski, Lauren and Lakhani, Sunil (2021). Implementation of precision oncology for breast cancer care in Brisbane: Q-IMPROvE. Brisbane Cancer Conference , Brisbane, QLD Australia, 25-26 Nov 2021.

Implementation of precision oncology for breast cancer care in Brisbane: Q-IMPROvE

2021

Journal Article

The mutational landscape of melanoma brain metastases presenting as the first visceral site of recurrence

Rabbie, Roy, Ferguson, Peter, Wong, Kim, Couturier, Dominique-Laurent, Moran, Una, Turner, Clinton, Emanuel, Patrick, Haas, Kerstin, Saunus, Jodi M., Davidson, Morgan R., Lakhani, Sunil R., Shivalingam, Brindha, Long, Georgina, Parkinson, Christine, Osman, Iman, Scolyer, Richard A., Corrie, Pippa and Adams, David J. (2021). The mutational landscape of melanoma brain metastases presenting as the first visceral site of recurrence. British Journal of Cancer, 124 (1), 156-160. doi: 10.1038/s41416-020-01090-2

The mutational landscape of melanoma brain metastases presenting as the first visceral site of recurrence

2021

Conference Publication

Implementation of precision oncology for breast cancer care in Brisbane: Q-IMPROvE

McCart Reed, Amy, McCurry, Therese, Simpson, Peter, Inglis, Po-ling, Ung, Owen, Murugappan, Kowsalya, Waddell, Nic, Snell, Cameron, Woodward, Natasha, Middleton, Kathryn, Walpole, Euan, O'Byrne, Ken, Cuff, Katharine, Andelkovic, Vlad, Roberts, Kate, Steinke, Karin, Santamaria, Gorane, McCarthy, Nicole, Mar Fan, Helen, Kalinowski, Lauren and Lakhani, Sunil (2021). Implementation of precision oncology for breast cancer care in Brisbane: Q-IMPROvE. Herston Symposium, Brisbane, QLD Australia, September 2021.

Implementation of precision oncology for breast cancer care in Brisbane: Q-IMPROvE

2021

Journal Article

Elevating CDCA3 levels enhances tyrosine kinase inhibitor sensitivity in TKI-resistant EGFR mutant non-small-cell lung cancer

Sahin, Katherine B., Shah, Esha T., Ferguson, Genevieve P., Molloy, Christopher, Kalita-de Croft, Priyakshi, Hayes, Sarah A., Hudson, Amanda, Colvin, Emily, Kamitakahara, Hannah, Harvie, Rozelle, Hasovits, Csilla, Khan, Tashbib, Duijf, Pascal H. G., Howell, Viive M., He, Yaowu, Bolderson, Emma, Hooper, John D., Lakhani, Sunil R., Richard, Derek J., O’Byrne, Kenneth J. and Adams, Mark N. (2021). Elevating CDCA3 levels enhances tyrosine kinase inhibitor sensitivity in TKI-resistant EGFR mutant non-small-cell lung cancer. Cancers, 13 (18) 4651, 4651. doi: 10.3390/cancers13184651

Elevating CDCA3 levels enhances tyrosine kinase inhibitor sensitivity in TKI-resistant EGFR mutant non-small-cell lung cancer

2021

Journal Article

Correction: McCart Reed et al. The Genomic Landscape of Lobular Breast Cancer. Cancers 2021, 13, 1950

McCart Reed, Amy E., Foong, Samuel, Kutasovic, Jamie R., Nones, Katia, Waddell, Nicola, Lakhani, Sunil R. and Simpson, Peter T. (2021). Correction: McCart Reed et al. The Genomic Landscape of Lobular Breast Cancer. Cancers 2021, 13, 1950. Cancers, 13 (16) 4010, 4010. doi: 10.3390/cancers13164010

Correction: McCart Reed et al. The Genomic Landscape of Lobular Breast Cancer. Cancers 2021, 13, 1950

2021

Journal Article

SP142 PD-L1 scoring shows high interobserver and intraobserver agreement in triple-negative breast carcinoma but overall low percentage agreement with other PD-L1 clones SP263 and 22C3

Pang, Jia-Min B., Castles, Belinda, Byrne, David J., Button, Peter, Hendry, Shona, Lakhani, Sunil R., Sivasubramaniam, Vanathi, Cooper, Wendy A., Armes, Jane, Millar, Ewan K.A., Raymond, Wendy, Roberts-Thomson, Samuel, Kumar, Beena, Burr, Marian, Selinger, Christina, Harvey, Kate, Chan, Charles, Beith, Jane, Clouston, David, O'Toole, Sandra A. and Fox, Stephen B. (2021). SP142 PD-L1 scoring shows high interobserver and intraobserver agreement in triple-negative breast carcinoma but overall low percentage agreement with other PD-L1 clones SP263 and 22C3. American Journal of Surgical Pathology, 45 (8), 1108-1117. doi: 10.1097/PAS.0000000000001701

SP142 PD-L1 scoring shows high interobserver and intraobserver agreement in triple-negative breast carcinoma but overall low percentage agreement with other PD-L1 clones SP263 and 22C3

2021

Journal Article

Adjuvant olaparib for patients with BRCA1- or BRCA2-mutated breast cancer

Tutt, Andrew N. J., Garber, Judy E., Kaufman, Bella, Viale, Giuseppe, Fumagalli, Debora, Rastogi, Priya, Gelber, Richard D., de Azambuja, Evandro, Fielding, Anitra, Balmaña, Judith, Domchek, Susan M., Gelmon, Karen A., Hollingsworth, Simon J., Korde, Larissa A., Linderholm, Barbro, Bandos, Hanna, Senkus, Elżbieta, Suga, Jennifer M., Shao, Zhimin, Pippas, Andrew W., Nowecki, Zbigniew, Huzarski, Tomasz, Ganz, Patricia A., Lucas, Peter C., Baker, Nigel, Loibl, Sibylle, McConnell, Robin, Piccart, Martine, Schmutzler, Rita ... Geyer, Charles E. (2021). Adjuvant olaparib for patients with BRCA1- or BRCA2-mutated breast cancer. New England Journal of Medicine, 384 (25), 2394-2405. doi: 10.1056/NEJMoa2105215

Adjuvant olaparib for patients with BRCA1- or BRCA2-mutated breast cancer

2021

Conference Publication

OlympiA: A phase III, multicenter, randomized, placebo-controlled trial of adjuvant olaparib after (neo)adjuvant chemotherapy in patients with germline BRCA1/2 mutations and high-risk HER2-negative early breast cancer

Tutt, Andrew, Garber, Judy Ellen, Kaufman, Bella, Viale, Giuseppe, Fumagalli, Debora, Rastogi, Priya, Gelber, Richard D., de Azambuja, Evandro, Fielding, Anitra, Gelpi, Judith Balmana, Gelmon, Karen A., Baker, Nigel, Arahmani, Amal, Senkus-Konefka, Elzbieta, Mc Fadden, Eleanor, Karantza, Vassiliki, Lakhani, Sunil R., Yothers, Greg, Campbell, Christine and Geyer, Charles E. (2021). OlympiA: A phase III, multicenter, randomized, placebo-controlled trial of adjuvant olaparib after (neo)adjuvant chemotherapy in patients with germline BRCA1/2 mutations and high-risk HER2-negative early breast cancer. Virtual Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Electr Network, Jun 04-08, 2021. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. doi: 10.1200/JCO.2021.39.15_suppl.LBA1

OlympiA: A phase III, multicenter, randomized, placebo-controlled trial of adjuvant olaparib after (neo)adjuvant chemotherapy in patients with germline BRCA1/2 mutations and high-risk HER2-negative early breast cancer

2021

Journal Article

Altered calcium influx pathways in cancer-associated fibroblasts

Sadras, Francisco, Stewart, Teneale A., Robitaille, Mélanie, Peters, Amelia A., Croft, Priyakshi Kalita-de, Soon, Patsy S., Saunus, Jodi M., Lakhani, Sunil R., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2021). Altered calcium influx pathways in cancer-associated fibroblasts. Biomedicines, 9 (6) 680, 1-13. doi: 10.3390/biomedicines9060680

Altered calcium influx pathways in cancer-associated fibroblasts