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2020

Journal Article

Id Proteins Promote a Cancer Stem Cell Phenotype in Mouse Models of Triple Negative Breast Cancer via Negative Regulation of Robo1

Teo, Wee S., Holliday, Holly, Karthikeyan, Nitheesh, Cazet, Aurélie S., Roden, Daniel L., Harvey, Kate, Konrad, Christina Valbirk, Murali, Reshma, Varghese, Binitha Anu, Thankamony, Archana P., Chan, Chia-Ling, McFarland, Andrea, Junankar, Simon, Ye, Sunny, Yang, Jessica, Nikolic, Iva, Shah, Jaynish S., Baker, Laura A., Millar, Ewan K. A., Naylor, Matthew J., Ormandy, Christopher J., Lakhani, Sunil R., Kaplan, Warren, Mellick, Albert S., O'Toole, Sandra A., Swarbrick, Alexander and Nair, Radhika (2020). Id Proteins Promote a Cancer Stem Cell Phenotype in Mouse Models of Triple Negative Breast Cancer via Negative Regulation of Robo1. Frontiers in Cell and Developmental Biology, 8 552, 552. doi: 10.3389/fcell.2020.00552

Id Proteins Promote a Cancer Stem Cell Phenotype in Mouse Models of Triple Negative Breast Cancer via Negative Regulation of Robo1

2020

Journal Article

Association of sperm-associated antigen 5 and treatment response in patients with estrogen receptor-positive breast cancer

Abdel-Fatah, Tarek M. A., Ball, Graham R., Thangavelu, Pulari U., Reid, Lynne E., McCart Reed, Amy E., Saunus, Jodi M., Duijf, Pascal H. G., Simpson, Peter T., Lakhani, Sunil R., Pongor, Lorinc, Gyorffy, Balázs, Moseley, Paul M., Green, Andrew R., Pockley, Alan G., Caldas, Carlos, Ellis, Ian O. and Chan, Stephen Y. T. (2020). Association of sperm-associated antigen 5 and treatment response in patients with estrogen receptor-positive breast cancer. JAMA Network Open, 3 (7) e209486, e209486. doi: 10.1001/jamanetworkopen.2020.9486

Association of sperm-associated antigen 5 and treatment response in patients with estrogen receptor-positive breast cancer

2020

Journal Article

Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer

Baker, Laura A., Holliday, Holly, Roden, Daniel, Krisp, Christoph, Wu, Sunny Z., Junankar, Simon, Serandour, Aurelien A., Mohammed, Hisham, Nair, Radhika, Sankaranarayanan, Geetha, Law, Andrew M. K., McFarland, Andrea, Simpson, Peter T., Lakhani, Sunil, Dodson, Eoin, Selinger, Christina, Anderson, Lyndal, Samimi, Goli, Hacker, Neville F., Lim, Elgene, Ormandy, Christopher J., Naylor, Matthew J., Simpson, Kaylene, Nikolic, Iva, O'Toole, Sandra, Kaplan, Warren, Cowley, Mark J., Carroll, Jason S., Molloy, Mark and Swarbrick, Alexander (2020). Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer. Breast Cancer Research , 22 (1) 63, 63. doi: 10.1186/s13058-020-01306-6

Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer

2020

Journal Article

Blocking immunosuppressive neutrophils deters pY696-EZH2–driven brain metastases

Zhang, Lin, Yao, Jun, Wei, Yongkun, Zhou, Zhifen, Li, Ping, Qu, Jingkun, Badu-Nkansah, Akosua, Yuan, Xiangliang, Huang, Yu-Wen, Fukumura, Kazutaka, Mao, Xizeng, Chang, Wei-Chao, Saunus, Jodi, Lakhani, Sunil, Huse, Jason T., Hung, Mien-Chie and Yu, Dihua (2020). Blocking immunosuppressive neutrophils deters pY696-EZH2–driven brain metastases. Science Translational Medicine, 12 (545) eaaz5387, eaaz5387. doi: 10.1126/scitranslmed.aaz5387

Blocking immunosuppressive neutrophils deters pY696-EZH2–driven brain metastases

2020

Journal Article

Digital spatial profiling application in breast cancer: a user’s perspective

McCart Reed, Amy E., Bennett, James, Kutasovic, Jamie R., Kalaw, Emarene, Ferguson, Kaltin, Yeong, Joe, Simpson, Peter T. and Lakhani, Sunil R. (2020). Digital spatial profiling application in breast cancer: a user’s perspective. Virchows Archiv, 477 (6), 885-890. doi: 10.1007/s00428-020-02821-9

Digital spatial profiling application in breast cancer: a user’s perspective

2020

Journal Article

Novel compound heterozygous variants in NHLRC2 in a patient with FINCA syndrome

Brodsky, Nina N., Boyarchuk, Oksana, Kovalchuk, Tetyana, Hariyan, Tetyana, Rice, Andrew, Ji, Weizhen, Khokha, Mustafa, Lakhani, Saquib and Lucas, Carrie L. (2020). Novel compound heterozygous variants in NHLRC2 in a patient with FINCA syndrome. Journal of Human Genetics, 65 (10), 911-915. doi: 10.1038/s10038-020-0776-0

Novel compound heterozygous variants in NHLRC2 in a patient with FINCA syndrome

2020

Journal Article

Tradeoff between metabolic i-proteasome addiction and immune evasion in triple-negative breast cancer

Adwal, Alaknanda, Kalita-de Croft, Priyakshi, Shakya, Reshma, Lim, Malcolm, Kalaw, Emarene, Taege, Lucinda D., McCart Reed, Amy E., Lakhani, Sunil R., Callen, David F. and Saunus, Jodi M. (2020). Tradeoff between metabolic i-proteasome addiction and immune evasion in triple-negative breast cancer. Life Science Alliance, 3 (7) e201900562, 1-12. doi: 10.26508/lsa.201900562

Tradeoff between metabolic i-proteasome addiction and immune evasion in triple-negative breast cancer

2020

Journal Article

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

Kos, Zuzana, Roblin, Elvire, Kim, Rim S., Michiels, Stefan, Gallas, Brandon D., Chen, Weijie, van de Vijver, Koen K., Goel, Shom, Adams, Sylvia, Demaria, Sandra, Viale, Giuseppe, Nielsen, Torsten O., Badve, Sunil S., Symmans, W. Fraser, Sotiriou, Christos, Rimm, David L., Hewitt, Stephen, Denkert, Carsten, Loibl, Sibylle, Luen, Stephen J., Bartlett, John M. S., Savas, Peter, Pruneri, Giancarlo, Dillon, Deborah A., Cheang, Maggie Chon U., Tutt, Andrew, Hall, Jacqueline A., Kok, Marleen, Horlings, Hugo M. ... International Immuno-Oncology Biomarker Working Group (2020). Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer. NPJ Breast Cancer, 6 (1) 17, 17. doi: 10.1038/s41523-020-0156-0

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

2020

Journal Article

Report on computational assessment of tumor infiltrating lymphocytes from the International Immuno-Oncology Biomarker Working Group

Amgad, Mohamed, Stovgaard, Elisabeth Specht, Balslev, Eva, Thagaard, Jeppe, Chen, Weijie, Dudgeon, Sarah, Sharma, Ashish, Kerner, Jennifer K., Denkert, Carsten, Yuan, Yinyin, AbdulJabbar, Khalid, Wienert, Stephan, Savas, Peter, Voorwerk, Leonie, Beck, Andrew H., Madabhushi, Anant, Hartman, Johan, Sebastian, Manu M., Horlings, Hugo M., Hudeček, Jan, Ciompi, Francesco, Moore, David A., Singh, Rajendra, Roblin, Elvire, Balancin, Marcelo Luiz, Mathieu, Marie-Christine, Lennerz, Jochen K., Kirtani, Pawan, Chen, I-Chun ... International Immuno-Oncology Biomarker Working Group (2020). Report on computational assessment of tumor infiltrating lymphocytes from the International Immuno-Oncology Biomarker Working Group. NPJ Breast Cancer, 6 (1) 16, 16. doi: 10.1038/s41523-020-0154-2

Report on computational assessment of tumor infiltrating lymphocytes from the International Immuno-Oncology Biomarker Working Group

2020

Conference Publication

Characterising clinicopathological and biological parameters predictive of outcome for patients diagnosed with invasive lobular carcinoma

Simpson, P., Reed, A. McCart, Kutasovic, J., Coorey, C., Kuo, L., Nguyen, H., Pei, W., Ong, J., Sokolova, A., Evans, E., Porter, A. and Lakhani, S. (2020). Characterising clinicopathological and biological parameters predictive of outcome for patients diagnosed with invasive lobular carcinoma. ESMO Breast Cancer Virtual Meeting, Online, 23-24 May 2020. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.annonc.2020.03.186

Characterising clinicopathological and biological parameters predictive of outcome for patients diagnosed with invasive lobular carcinoma

2020

Journal Article

Estrogen and progesterone receptor testing in breast cancer: American society of clinical oncology/college of American pathologists guideline update

Allison, Kimberly H., Hammond, M. Elizabeth H., Dowsett, Mitchell, McKernin, Shannon E., Carey, Lisa A., Fitzgibbons, Patrick L., Hayes, Daniel F., Lakhani, Sunil R., Chavez-MacGregor, Mariana, Perlmutter, Jane, Perou, Charles M., Regan, Meredith M., Rimm, David L., Symmans, W. Fraser, Torlakovic, Emina E., Varella, Leticia, Viale, Giuseppe, Weisberg, Tracey F., McShane, Lisa M. and Wolff, Antonio C. (2020). Estrogen and progesterone receptor testing in breast cancer: American society of clinical oncology/college of American pathologists guideline update. Archives of Pathology and Laboratory Medicine, 144 (5), 545-563. doi: 10.5858/arpa.2019-0904-SA

Estrogen and progesterone receptor testing in breast cancer: American society of clinical oncology/college of American pathologists guideline update

2020

Journal Article

Estrogen and progesterone receptor testing in breast cancer: ASCO/CAP guideline update

Allison, Kimberly H., Hammond, M. Elizabeth H., Dowsett, Mitchell, McKernin, Shannon E., Carey, Lisa A., Fitzgibbons, Patrick L., Hayes, Daniel F., Lakhani, Sunil R., Chavez-MacGregor, Mariana, Perlmutter, Jane, Perou, Charles M., Regan, Meredith M., Rimm, David L., Symmans, W. Fraser, Torlakovic, Emina E., Varella, Leticia, Viale, Giuseppe, Weisberg, Tracey F., McShane, Lisa M. and Wolff, Antonio C. (2020). Estrogen and progesterone receptor testing in breast cancer: ASCO/CAP guideline update. Journal of Clinical Oncology, 38 (12), 1346-1366. doi: 10.1200/JCO.19.02309

Estrogen and progesterone receptor testing in breast cancer: ASCO/CAP guideline update

2020

Journal Article

American registry of pathology expert opinions: The spectrum of lobular carcinoma in situ: Diagnostic features and clinical implications

Schnitt, Stuart J., Brogi, Edi, Chen, Yunn-Yi, King, Tari A. and Lakhani, Sunil R. (2020). American registry of pathology expert opinions: The spectrum of lobular carcinoma in situ: Diagnostic features and clinical implications. Annals of Diagnostic Pathology, 45 151481, 151481. doi: 10.1016/j.anndiagpath.2020.151481

American registry of pathology expert opinions: The spectrum of lobular carcinoma in situ: Diagnostic features and clinical implications

2020

Journal Article

Morphologic and Genomic Heterogeneity in the Evolution and Progression of Breast Cancer

Kutasovic, Jamie R., McCart Reed, Amy E., Sokolova, Anna, Lakhani, Sunil R. and Simpson, Peter T. (2020). Morphologic and Genomic Heterogeneity in the Evolution and Progression of Breast Cancer. Cancers, 12 (4) 848, 848. doi: 10.3390/cancers12040848

Morphologic and Genomic Heterogeneity in the Evolution and Progression of Breast Cancer

2020

Journal Article

Pitfalls and controversies in pathology impacting breast cancer management

Kim, Woo Gyeong, Cummings, Margaret C. and Lakhani, Sunil R. (2020). Pitfalls and controversies in pathology impacting breast cancer management. Expert Review of Anticancer Therapy, 20 (3), 205-219. doi: 10.1080/14737140.2020.1738222

Pitfalls and controversies in pathology impacting breast cancer management

2020

Journal Article

The 2019 WHO classification of tumours of the breast

Hoon Tan, Puay, Ellis, Ian, Allison, Kimberly, Brogi, Edi, Fox, Stephen B., Lakhani, Sunil, Lazar, Alexander J., Morris, Elizabeth A., Sahin, Aysegul, Salgado, Roberto, Sapino, Anna, Sasano, Hironobu, Schnitt, Stuart, Sotiriou, Christos, van Diest, Paul, White, Valerie A., Lokuhetty, Dilani, Cree, Ian A. and WHO Classification of Tumours Editorial Board (2020). The 2019 WHO classification of tumours of the breast. Histopathology, 77 (2) his.14091, 181-185. doi: 10.1111/his.14091

The 2019 WHO classification of tumours of the breast

2020

Journal Article

Pan-cancer analysis of whole genomes

Campbell, Peter J., Getz, Gad, Korbel, Jan O., Stuart, Joshua M., Jennings, Jennifer L., Stein, Lincoln D., Perry, Marc D., Nahal-Bose, Hardeep K., Ouellette, B. F. Francis, Li, Constance H., Rheinbay, Esther, Nielsen, G. Petur, Sgroi, Dennis C., Wu, Chin-Lee, Faquin, William C., Deshpande, Vikram, Boutros, Paul C., Lazar, Alexander J., Hoadley, Katherine A., Louis, David N., Dursi, L. Jonathan, Yung, Christina K., Bailey, Matthew H., Saksena, Gordon, Raine, Keiran M., Buchhalter, Ivo, Kleinheinz, Kortine, Schlesner, Matthias, Zhang, Junjun ... Hamdy, Freddie C. (2020). Pan-cancer analysis of whole genomes. Nature, 578 (7793), 82-93. doi: 10.1038/s41586-020-1969-6

Pan-cancer analysis of whole genomes

2020

Journal Article

Non-coding RNAs underlie genetic predisposition to breast cancer

Moradi Marjaneh, Mahdi, Beesley, Jonathan, O'Mara, Tracy A., Mukhopadhyay, Pamela, Koufariotis, Lambros T., Kazakoff, Stephen, Hussein, Nehal, Fachal, Laura, Bartonicek, Nenad, Hillman, Kristine M., Kaufmann, Susanne, Sivakumaran, Haran, Smart, Chanel E., McCart Reed, Amy E., Ferguson, Kaltin, Saunus, Jodi M., Lakhani, Sunil R., Barnes, Daniel R., Antoniou, Antonis C., Dinger, Marcel E., Waddell, Nicola, Easton, Douglas F., Dunning, Alison M., Chenevix-Trench, Georgia, Edwards, Stacey L. and French, Juliet D. (2020). Non-coding RNAs underlie genetic predisposition to breast cancer. Genome Biology, 21 (1) 7, 7. doi: 10.1186/s13059-019-1876-z

Non-coding RNAs underlie genetic predisposition to breast cancer

2020

Journal Article

Survival and disease characteristics of de novo versus recurrent metastatic breast cancer in a cohort of young patients

McKenzie, Hayley S., Maishman, Tom, Simmonds, Peter, Durcan, Lorraine, Altman, Douglas G., Jones, Louise, Evans, Gareth, Thompson, Alastair M., Pharaoh, Paul, Hanby, Andrew, Lakhani, Sunil, Eeles, Ros, Gilbert, Fiona J., Hamed, Hisham, Hodgson, Shirley, Simmonds, Peter, Eccles, Diana, Eccles, Diana, Copson, Ellen and POSH Steering Group (2020). Survival and disease characteristics of de novo versus recurrent metastatic breast cancer in a cohort of young patients. British Journal of Cancer, 122 (11), 1618-1629. doi: 10.1038/s41416-020-0784-z

Survival and disease characteristics of de novo versus recurrent metastatic breast cancer in a cohort of young patients

2020

Book Chapter

Columnar cell lesions

Cummings, Margaret C., Simpson, Peter T. and Lakhani, Sunil R. (2020). Columnar cell lesions. Breast Pathology. Encyclopedia of Pathology. (pp. 71-79) edited by Anna Sapino and Janina Kulka. Cham, Switzerland: Springer. doi: 10.1007/978-3-319-62539-3

Columnar cell lesions