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2015 Journal Article Invasive lobular carcinoma of the breast: morphology, biomarkers and 'omicsMcCart Reed, Amy E., Kutasovic, Jamie R., Lakhani, Sunil R. and Simpson, Peter T. (2015). Invasive lobular carcinoma of the breast: morphology, biomarkers and 'omics. Breast Cancer Research, 17 (12) 12, 1-11. doi: 10.1186/s13058-015-0519-x |
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2015 Journal Article ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotypeJunankar, Simon, Baker, Laura A., Roden, Daniel L., Nair, Radhika, Elsworth, Ben, Gallego-Ortega, David, Lacaze, Paul, Cazet, Aurelie, Nikolic, Iva, Teo, Wee Siang, Yang, Jessica, McFarland, Andrea, Harvey, Kate, Naylor, Matthew J., Lakhani, Sunil R., Simpson, Peter T., Raghavendra, Ashwini, Saunus, Jodi, Madore, Jason, Kaplan, Warren, Ormandy, Christopher, Millar, Ewan K. A., O'Toole, Sandra, Yun, Kyuson and Swarbrick, Alexander (2015). ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype. Nature Communications, 6 (1) 6548, 6548.1-6548.12. doi: 10.1038/ncomms7548 |
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2014 Journal Article Complex-based analysis of dysregulated cellular processes in cancerSrihari, Sriganesh, Madhamshettiwar, Piyush B., Song, Sarah, Liu, Chao, Simpson, Peter T., Khanna, Kumkum and Ragan, Mark A. (2014). Complex-based analysis of dysregulated cellular processes in cancer. BMC Systems Biology, 8 (Supplement 4) S1. doi: 10.1186/1752-0509-8-S4-S1 |
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2014 Journal Article Genomic catastrophes frequently arise in esophageal adenocarcinoma and drive tumorigenesisNones, Katia, Waddell, Nicola, Wayte, Nicci, Patch, Ann-Marie, Bailey, Peter, Newell, Felicity, Holmes, Oliver, Fink, J. Lynn, Quinn, Michael C. J., Tang, Yue Hang, Lampe, Guy, Quek, Kelly, Loffler, Kelly A., Manning, Suzanne, Idrisoglu, Senel, Miller, David, Xu, Qinying, Waddell, Nick, Wilson, Peter J., Bruxner, Timothy J. C., Christ, Angelika N., Harliwong, Ivon, Nourse, Craig, Nourbakhsh, Ehsan, Anderson, Matthew, Kazakoff, Stephen, Leonard, Conrad, Wood, Scott, Simpson, Peter T. ... Barbour, Andrew P. (2014). Genomic catastrophes frequently arise in esophageal adenocarcinoma and drive tumorigenesis. Nature Communications, 5 (1) 6224, 5224.1-5224.9. doi: 10.1038/ncomms6224 |
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2014 Journal Article Erratum: Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancerAl-Ejeh, F, Simpson, P T, Saunus, J M, Klein, K, Kalimutho, M, Shi, W, Miranda, M, Kutasovic, J, Raghavendra, A, Madore, J, Reid, L, Krause, L, Chenevix-Trench, G, Lakhani, S R and Khanna, K K (2014). Erratum: Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer. Oncogenesis, 3 (10) e124, e124-e124. doi: 10.1038/oncsis.2014.41 |
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2014 Journal Article Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancerOwens, Thomas W., Rogers, Renee L., Best, Sarah A., Ledger, Anita, Mooney, Anne-Marie, Ferguson, Alison, Shore, Paul, Swarbrick, Alexander, Ormandy, Christopher J., Simpson, Peter T., Carroll, Jason S., Visvader, Jane E. and Naylor, Matthew J. (2014). Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancer. Cancer Research, 74 (18), 5277-5286. doi: 10.1158/0008-5472.CAN-14-0053 |
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2014 Journal Article Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomesTubio, Jose M. C., Li, Yilong, Ju, Young S., Martincorena, Inigo, Cooke, Susanna L., Tojo, Marta, Gundem, Gunes, Pipinikas, Christodoulos P., Zamora, Jorge, Raine, Keiran, Menzies, Andrew, Roman-Garcia, Pablo, Fullam, Anthony, Gerstung, Moritz, Shlien, Adam, Tarpey, Patrick S., Papaemmanuil, Elli, Knappskog, Stian, Van Loo, Peter, Ramakrishna, Manasa, Davies, Helen R., Marshall, John, Wedge, David C., Teague, Jon W., Butler, Adam P., Nik-Zainal, Serena, Alexandrov, Ludmil, Behjati, Sam, Yates, Lucy R. ... Simpson, Peter (2014). Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes. Science, 345 (6196) 1251343, 1251343.1-1251343.12. doi: 10.1126/science.1251343 |
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2014 Journal Article Intratumour heterogeneity in the progression to breast cancer metastasisKutasovic, Jamie R., Sim, Sarah Y. M., McCart Reed, Amy E., Cummings, Margaret C. and Simpson, Peter T. (2014). Intratumour heterogeneity in the progression to breast cancer metastasis. Cancer Forum, 38 (2), 138-142. |
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2014 Journal Article Molecular classification of breast cancerVuong, Darina, Simpson, Peter T., Green, Benjamin, Cummings, Margaret C. and Lakhani, Sunil R. (2014). Molecular classification of breast cancer. Virchows Archiv, 465 (1), 1-14. doi: 10.1007/s00428-014-1593-7 |
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2014 Journal Article A fine-scale dissection of the DNA double-strand break repair machinery and its implications for breast cancer therapyLiu, Chao, Srihari, Sriganesh, Le Cao, Kim-Anh, Chenevix-Trench, Georgia, Simpson, Peter T., Ragan, Mark A. and Khanna, Kum Kum (2014). A fine-scale dissection of the DNA double-strand break repair machinery and its implications for breast cancer therapy. Nucleic Acids Research, 42 (10), 6106-6127. doi: 10.1093/nar/gku284 |
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2014 Journal Article Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancerAl-Ejeh, F., Simpson, P. T., Sanus, J. M., Klein, K., Kalimutho, M., Shi, W., Miranda, M., Kutasovic, J., Raghavendra, A., Madore, J., Reid, L., Krause, L., Chenevix-Trench, G., Lakhani, S. R. and Khanna, K. K. (2014). Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer. Oncogenesis, 3 (4) e100, 1-12. doi: 10.1038/oncsis.2014.14 |
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2014 Journal Article Processed pseudogenes acquired somatically during cancer developmentCooke, Susanna L., Shlien, Adam, Marshall, John, Pipinikas, Christodoulos P., Martincorena, Inigo, Tubio, Jose M. C., Li, Yilong, Menzies, Andrew, Mudie, Laura, Ramakrishna, Manasa, Yates, Lucy, Davies, Helen, Bolli, Niccolo, Bignell, Graham R., Tarpey, Patrick S., Behjati, Sam, Nik-Zainal, Serena, Papaemmanuil, Elli, Teixeira, Vitor H., Raine, Keiran, O'Meara, Sarah, Dodoran, Maryam S., Teague, Jon W., Butler, Adam P., Iacobuzio-Donahue, Christine, Santarius, Thomas, Grundy, Richard G., Malkin, David, Greaves, Mel ... Lakhani, Sunil R. (2014). Processed pseudogenes acquired somatically during cancer development. Nature Communications, 5 (1) 3644, 3644.1-3644.9. doi: 10.1038/ncomms4644 |
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2014 Journal Article Mutations in EGFR, BRAF and RAS are rare in triple-negative and basal-like breast cancers from Caucasian womenTilch, E., Seidens, T., Cocciardi, S., Reid, L. E., Byrne, D., Simpson, P. T., Vargas, A. C., Cummings, M. C., Fox, S. B., Lakhani, S. R. and Chenevix Trench, G. (2014). Mutations in EGFR, BRAF and RAS are rare in triple-negative and basal-like breast cancers from Caucasian women. Breast Cancer Research and Treatment, 143 (2), 385-392. doi: 10.1007/s10549-013-2798-1 |
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2014 Journal Article Rad51 supports triple negative breast cancer metastasisWiegmans, Adrian P., Al-Ejeh, Fares, Chee, Nicole, Yap, Pei-Yi, Gorski, Julia J., Da Silva, Leonard, Bolderson, Emma, Chenevix-Trench, Georgia, Anderson, Robin, Simpson, Peter T., Lakhani, Sunil R. and Khanna, Kum Kum (2014). Rad51 supports triple negative breast cancer metastasis. Oncotarget, 5 (10), 3261-3272. doi: 10.18632/oncotarget.1923 |
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2014 Journal Article Metastatic progression of breast cancer: Insights from 50 years of autopsiesCummings, Margaret C., Simpson, Peter T., Reid, Lynne E., Jayanthan, Janani, Skerman, Joanna, Song, Sarah, McCart Reed, Amy E., Kutasovic, Jamie R., Morey, Adrienne L., Marquart, Louise, O'Rourke, Peter and Lakhani, Sunil R. (2014). Metastatic progression of breast cancer: Insights from 50 years of autopsies. Journal of Pathology, 232 (1), 23-31. doi: 10.1002/path.4288 |
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2014 Journal Article Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancerAl-Ejeh, Fares, Miranda, Mariska, Shi,Wei, Simpson, Peter T., Song, Sarah, Vargas, Ana Cristina, Saunus, Jodi M., Smart, Chanel E., Mariasegaram, Mythily, Wiegmans, Adrian P., Chenevix-Trench, Georgia, Lakhani, Sunil R. and Khanna, Kum Kum (2014). Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancer. Oncotarget, 5 (10), 3145-3158. doi: 10.18632/oncotarget.1865 |
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2013 Journal Article miR-139-5p is a regulator of metastatic pathways in breast cancerKrishnan, Keerthana, Steptoe, Anita, Martin, Hilary, Pattabiraman, Diwakar R., Nones, Katia, Waddell, Nicola, Mariasegaram, Mythily, Simpson, Peter T., Lakhani, Sunil R., Vlassov, Alexander, Grimmond, Sean M. and Cloonan, Nicole (2013). miR-139-5p is a regulator of metastatic pathways in breast cancer. RNA, 19 (12), 1767-1780. doi: 10.1261/rna.042143.113 |
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2013 Journal Article Thrombospondin-4 expression is activated during the stromal response to invasive breast cancerMcCart Reed, Amy E., Song, Sarah, Kutasovic, Jamie R., Reid, Lynne E., Valle, Jordan M., Vargas, Ana Cristina, Smart, Chanel E. and Simpson, Peter T. (2013). Thrombospondin-4 expression is activated during the stromal response to invasive breast cancer. Virchows Archiv, 463 (4), 535-545. doi: 10.1007/s00428-013-1468-3 |
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2013 Journal Article Mammographic and ultrasound features of invasive lobular carcinoma of the breastPorter, Alan J., Evans, Elizabeth B., Foxcroft, Loani M., Simpson, Peter T. and Lakhani, Sunil R. (2013). Mammographic and ultrasound features of invasive lobular carcinoma of the breast. Journal of Medical Imaging and Radiation Oncology, 58 (1), 1-10. doi: 10.1111/1754-9485.12080 |
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2013 Journal Article In vitro analysis of breast cancer cell line tumourspheres and primary human breast epithelia mammospheres demonstrates inter- and intrasphere heterogeneitySmart, Chanel E., Morrison, Brian J., Saunus, Jodi M., Vargas, Ana Cristina, Keith, Patricia, Reid, Lynne, Wockner, Leesa, Amiri, Marjan Askarian, Sarkar, Debina, Simpson, Peter T., Clarke, Catherine, Schmidt, Chris W., Reynolds, Brent A., Lakhani, Sunil R. and Lopez, J. Alejandro (2013). In vitro analysis of breast cancer cell line tumourspheres and primary human breast epithelia mammospheres demonstrates inter- and intrasphere heterogeneity. PloS One, 8 (6) e64388, e64388. doi: 10.1371/journal.pone.0064388 |
