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2016

Journal Article

Editorial overview: membrane traffic and cell polarity

Bryant, David M. and Yap, Alpha S. (2016). Editorial overview: membrane traffic and cell polarity. Traffic, 17 (12), 1231-1232. doi: 10.1111/tra.12433

Editorial overview: membrane traffic and cell polarity

2016

Journal Article

Contact inhibition of locomotion and mechanical cross-talk between cell-cell and cell-substrate adhesion determine the pattern of junctional tension in epithelial cell aggregates

Coburn, Luke, Lopez, Hender, Caldwell, Benjamin J., Moussa, Elliott, Yap, Chloe, Priya, Rashmi, Noppe, Adrian, Roberts, Anthony P., Lobaskin, Vladimir, Yap, Alpha S., Neufeld, Zoltan and Gomez, Guillermo A. (2016). Contact inhibition of locomotion and mechanical cross-talk between cell-cell and cell-substrate adhesion determine the pattern of junctional tension in epithelial cell aggregates. Molecular Biology of the Cell, 27 (22), 3436-3448. doi: 10.1091/mbc.E16-04-0226

Contact inhibition of locomotion and mechanical cross-talk between cell-cell and cell-substrate adhesion determine the pattern of junctional tension in epithelial cell aggregates

2016

Journal Article

Coronin 1B supports RhoA signaling at cell-cell junctions through myosin II

Priya, Rashmi, Wee, Kenneth, Budnar, Srikanth, Gomez, Guillermo A., Yap, Alpha S. and Michael, Magdalene (2016). Coronin 1B supports RhoA signaling at cell-cell junctions through myosin II. Cell Cycle, 15 (22), 1-9. doi: 10.1080/15384101.2016.1234549

Coronin 1B supports RhoA signaling at cell-cell junctions through myosin II

2016

Journal Article

Cycling Rho for tissue contraction

Teo, Jessica L. and Yap, Alpha S. (2016). Cycling Rho for tissue contraction. Journal of Cell Biology, 214 (5), 495-498. doi: 10.1083/jcb.201608017

Cycling Rho for tissue contraction

2016

Journal Article

Resolution of novel pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling

Humphrey, Emily S., Su, Shih-Ping, Nagrial, Adnan M., Hochgraefe, Falko, Pajic, Marina, Lehrbach, Gillian M., Parton, Robert G., Yap, Alpha S., Horvath, Lisa G., Chang, David K., Biankin, Andrew V., Wu, Jianmin and Daly, Roger J. (2016). Resolution of novel pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling. Molecular and Cellular Proteomics, 15 (8), 2671-2685. doi: 10.1074/mcp.M116.058313

Resolution of novel pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling

2016

Journal Article

Remodeling the zonula adherens in response to tension and the role of afadin in this response

Choi, Wangsun, Acharya, Bipul R., Peyret, Grégoire, Fardin, Marc-Antoine, Mège, René-Marc, Ladoux, Benoit, Yap, Alpha S., Fanning, Alan S. and Peifer, Mark (2016). Remodeling the zonula adherens in response to tension and the role of afadin in this response. Journal of Cell Biology, 213 (2), 243-260. doi: 10.1083/jcb.201506115

Remodeling the zonula adherens in response to tension and the role of afadin in this response

2016

Journal Article

Neogenin recruitment of the WAVE regulatory complex maintains adherens junction stability and tension

Lee, Natalie K., Fok, Ka Wai, White, Amanda, Wilson, Nicole H., O’Leary, Conor J., Cox, Hayley L., Michael, Magdalene, Yap, Alpha S. and Cooper, Helen M. (2016). Neogenin recruitment of the WAVE regulatory complex maintains adherens junction stability and tension. Nature Communications, 7 (11082) 11082, 11082. doi: 10.1038/ncomms11082

Neogenin recruitment of the WAVE regulatory complex maintains adherens junction stability and tension

2016

Journal Article

Biomechanical guidance helps elongate a lumen

Wee, Kenneth and Yap, Alpha S. (2016). Biomechanical guidance helps elongate a lumen. Nature Cell Biology, 18 (3), 255-257. doi: 10.1038/ncb3319

Biomechanical guidance helps elongate a lumen

2016

Journal Article

The Nuclear Receptor, RORγ, Regulates Pathways Necessary for Breast Cancer Metastasis

Oh, Tae Gyu, Wang, Shu-Ching M., Acharya, Bipul R., Goode, Joel M., Graham, J. Dinny, Clarke, Christine L., Yap, Alpha S. and Muscat, George E. O. (2016). The Nuclear Receptor, RORγ, Regulates Pathways Necessary for Breast Cancer Metastasis. EBioMedicine, 6, 59-72. doi: 10.1016/j.ebiom.2016.02.028

The Nuclear Receptor, RORγ, Regulates Pathways Necessary for Breast Cancer Metastasis

2016

Journal Article

Coronin 1B reorganizes the architecture of f-actin networks for contractility at steady-state and apoptotic adherens junctions

Michael, Magdalene, Meiring, Joyce C. M., Acharya, Bipul R., Matthews, Daniel R., Verma, Suzie, Han, Siew Ping, Hill, Michelle M., Parton, Robert G., Gomez, Guillermo A. and Yap, Alpha S. (2016). Coronin 1B reorganizes the architecture of f-actin networks for contractility at steady-state and apoptotic adherens junctions. Developmental Cell, 37 (1), 58-71. doi: 10.1016/j.devcel.2016.03.008

Coronin 1B reorganizes the architecture of f-actin networks for contractility at steady-state and apoptotic adherens junctions

2016

Journal Article

Pli Selon Pli: mechanochemical feedback and the morphogenetic role of contractility at cadherin cell-cell junctions

Acharya, Bipul R. and Yap, Alpha S. (2016). Pli Selon Pli: mechanochemical feedback and the morphogenetic role of contractility at cadherin cell-cell junctions. Current Topics in Developmental Biology, 117, 631-646. doi: 10.1016/bs.ctdb.2015.10.021

Pli Selon Pli: mechanochemical feedback and the morphogenetic role of contractility at cadherin cell-cell junctions

2015

Journal Article

Towards a dynamic understanding of cadherin-based mechanobiology

Hoffman, Brenton D. and Yap, Alpha S. (2015). Towards a dynamic understanding of cadherin-based mechanobiology. Trends in Cell Biology, 25 (12), 803-814. doi: 10.1016/j.tcb.2015.09.008

Towards a dynamic understanding of cadherin-based mechanobiology

2015

Journal Article

Mammalian farnesyltransferase α subunit regulates vacuolar protein sorting-associated protein 4A (Vps4A) – dependent intracellular trafficking through recycling endosomes

Marta Kubala, Norwood, Suzanne, Gomez, Guillermo, Jones, Alun, Johnston, Wayne A., Yap, Alpha S.K., Mureev, Sergey and Alexandrov, Kirill (2015). Mammalian farnesyltransferase α subunit regulates vacuolar protein sorting-associated protein 4A (Vps4A) – dependent intracellular trafficking through recycling endosomes. Biochemical and Biophysical Research Communications, 468 (4), 580-586. doi: 10.1016/j.bbrc.2015.10.148

Mammalian farnesyltransferase α subunit regulates vacuolar protein sorting-associated protein 4A (Vps4A) – dependent intracellular trafficking through recycling endosomes

2015

Journal Article

Adherens Junctions Revisualized: Organizing Cadherins as Nanoassemblies

Yap, Alpha S., Gomez, Guillermo A. and Parton, Robert G. (2015). Adherens Junctions Revisualized: Organizing Cadherins as Nanoassemblies. Developmental Cell, 35 (1) 3402, 12-20. doi: 10.1016/j.devcel.2015.09.012

Adherens Junctions Revisualized: Organizing Cadherins as Nanoassemblies

2015

Journal Article

Modelling wound closure in an epithelial cell sheet using the cellular Potts model

Noppe, Adrian R., Roberts, Anthony P., Yap, Alpha S., Gomez, Guillermo A. and Neufeld, Zoltan (2015). Modelling wound closure in an epithelial cell sheet using the cellular Potts model. Integrative Biology (United Kingdom), 7 (10), 1253-1264. doi: 10.1039/c5ib00053j

Modelling wound closure in an epithelial cell sheet using the cellular Potts model

2015

Journal Article

Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions

Priya, Rashmi, Gomez, Guillermo A., Budnar, Srikanth, Verma, Suzie, Cox, Hayley L., Hamilton, Nicholas A. and Yap, Alpha S. (2015). Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions. Nature Cell Biology, 17 (10), 1282-1293. doi: 10.1038/ncb3239

Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions

2015

Journal Article

Making a choice: how cadherin switching controls cell migration

Priya, Rashmi and Yap, Alpha S. (2015). Making a choice: how cadherin switching controls cell migration. Developmental Cell, 34 (4) 3369, 383-384. doi: 10.1016/j.devcel.2015.08.002

Making a choice: how cadherin switching controls cell migration

2015

Journal Article

Seeing and believing: recent advances in imaging cell-cell interactions

Yap, Alpha S., Michael, Magdalene and Parton, Robert G. (2015). Seeing and believing: recent advances in imaging cell-cell interactions. F1000Research, 4 (F1000 Faculty Rev) 273, 273.1-273.8. doi: 10.12688/f1000research.6435.1

Seeing and believing: recent advances in imaging cell-cell interactions

2015

Journal Article

Mutations in SIPA1L3 cause eye defects through disruption of cell polarity and cytoskeleton organization

Greenlees, Rebecca, Mihelec, Marija, Yousoof, Saira, Speidel, Daniel, Wu, Selwin K., Rinkwitz, Silke, Prokudin, Ivan, Perveen, Rahat, Cheng, Anson, Ma, Alan, Nash, Benjamin, Gillespie, Rachel, Loebel, David A. F., Clayton-Smith, Jill, Lloyd, I. Christopher, Grigg, John R., Tam, Patrick P. L., Yap, Alpha S., Becker, Thomas S., Black, Graeme C. M., Semina, Elena and Jamieson, Robyn V. (2015). Mutations in SIPA1L3 cause eye defects through disruption of cell polarity and cytoskeleton organization. Human Molecular Genetics, 24 (20), 5789-5804. doi: 10.1093/hmg/ddv298

Mutations in SIPA1L3 cause eye defects through disruption of cell polarity and cytoskeleton organization

2015

Journal Article

E-cadherin junctions as active mechanical integrators in tissue dynamics

Lecuit, Thomas and Yap, Alpha S. (2015). E-cadherin junctions as active mechanical integrators in tissue dynamics. Nature Cell Biology, 17 (5), 533-539. doi: 10.1038/ncb3136

E-cadherin junctions as active mechanical integrators in tissue dynamics