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2017

Journal Article

Author Correction: tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1

Liang, Xuan, Budnar, Srikanth, Gupta, Shafali, Verma, Suzie, Han, Siew-Ping, Hill, Michelle M., Daly, Roger J, Parton, Robert G., Hamilton, Nicholas A., Gomez, Guillermo A. and Yap, Alpha S. (2017). Author Correction: tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1. Nature Communications, 8 (2021) 2021, 2021. doi: 10.1038/s41467-017-02131-w

Author Correction: tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1

2017

Journal Article

Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1

Liang, Xuan, Budnar, Srikanth, Gupta, Shafali, Verma, Suzie, Han, Siew-Ping, Hill, Michelle M., Daly, Roger J., Parton, Robert G., Hamilton, Nicholas A., Gomez, Guillermo A. and Yap, Alpha S. (2017). Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1. Nature Communications, 8 (1) 790, 790. doi: 10.1038/s41467-017-00797-w

Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1

2017

Journal Article

Versatile Scaffold: Extrajunctional Roles for α-Catenin

Budnar, Srikanth and Yap, Alpha S. (2017). Versatile Scaffold: Extrajunctional Roles for α-Catenin. Developmental Cell, 43 (4), 381-382. doi: 10.1016/j.devcel.2017.11.004

Versatile Scaffold: Extrajunctional Roles for α-Catenin

2017

Journal Article

Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish

Lagendijk, Anne Karine, Gomez, Guillermo A, Baek, Sungmin, Hesselson, Daniel, Hughes, William E, Paterson, Scott, Conway, Daniel E, Belting, Heinz-Georg, Affolter, Markus, Smith, Kelly A, Schwartz, Martin A, Yap, Alpha S and Hogan, Benjamin M (2017). Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish. Nature communications, 8 (1) 1402, 1-12. doi: 10.1038/s41467-017-01325-6

Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish

2017

Journal Article

Caveolae protect notochord cells against catastrophic mechanical failure during development

Lim, Ye-Wheen, Lo, Harriet P., Ferguson, Charles, Martel, Nick, Giacomotto, Jean, Gomez, Guillermo A., Yap, Alpha S., Hall, Thomas E. and Parton, Robert G. (2017). Caveolae protect notochord cells against catastrophic mechanical failure during development. Current Biology, 27 (13), 1968-1981.e7. doi: 10.1016/j.cub.2017.05.067

Caveolae protect notochord cells against catastrophic mechanical failure during development

2017

Journal Article

In life there is death: How epithelial tissue barriers are preserved despite the challenge of apoptosis

Duszyc, Kinga, Gomez, Guillermo A., Schroder, Kate, Sweet, Matthew J. and Yap, Alpha S. (2017). In life there is death: How epithelial tissue barriers are preserved despite the challenge of apoptosis. Tissue Barriers, 5 (4) e1345353, e1345353. doi: 10.1080/21688370.2017.1345353

In life there is death: How epithelial tissue barriers are preserved despite the challenge of apoptosis

2017

Conference Publication

Adherens junctions, force‐sensing, and epithelial homeostasis

Yap, Alpha (2017). Adherens junctions, force‐sensing, and epithelial homeostasis. Experimental Biology 2017 Meeting, Chicago, IL United States, 22-26 April 2017. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1096/fasebj.31.1_supplement.242.3

Adherens junctions, force‐sensing, and epithelial homeostasis

2017

Journal Article

Mammalian diaphanous 1 mediates a pathway for E-cadherin to stabilize epithelial barriers through junctional contractility

Acharya, Bipul R., Wu, Selwin K., Lieu, Zi Zhao, Parton, Robert G., Grill, Stephan W., Bershadsky, Alexander D., Gomez, Guillermo A. and Yap, Alpha S. (2017). Mammalian diaphanous 1 mediates a pathway for E-cadherin to stabilize epithelial barriers through junctional contractility. Cell Reports, 18 (12), 2854-2867. doi: 10.1016/j.celrep.2017.02.078

Mammalian diaphanous 1 mediates a pathway for E-cadherin to stabilize epithelial barriers through junctional contractility

2017

Journal Article

Laser-mediated rupture of chlamydial inclusions triggers pathogen egress and host cell necrosis

Kerr, Markus C., Gomez, Guillermo A., Ferguson, Charles, Tanzer, Maria C., Murphy, James M., Yap, Alpha S., Parton, Robert G., Huston, Wilhelmina M. and Teasdale, Rohan D. (2017). Laser-mediated rupture of chlamydial inclusions triggers pathogen egress and host cell necrosis. Nature Communications, 8 (1) 14729, 14729. doi: 10.1038/ncomms14729

Laser-mediated rupture of chlamydial inclusions triggers pathogen egress and host cell necrosis

2017

Journal Article

Bistable front dynamics in a contractile medium: Travelling wave fronts and cortical advection define stable zones of RhoA signaling at epithelial adherens junctions

Priya, Rashmi, Gomez, Guillermo A., Budnar, Srikanth, Acharya, Bipul R., Czirok, Andras, Yap, Alpha S. and Neufeld, Zoltan (2017). Bistable front dynamics in a contractile medium: Travelling wave fronts and cortical advection define stable zones of RhoA signaling at epithelial adherens junctions. Plos Computational Biology, 13 (3) e1005411, e1005411. doi: 10.1371/journal.pcbi.1005411

Bistable front dynamics in a contractile medium: Travelling wave fronts and cortical advection define stable zones of RhoA signaling at epithelial adherens junctions

2017

Journal Article

Correction to: Tmem2 regulates embryonic Vegf signaling by controlling hyaluronic acid turnover (Developmental Cell 40, 2017, 123-136)

De Angelis, Jessica E., Lagendijk, Anne K., Chen, Huijun, Tromp, Alisha, Bower, Neil I., Tunny, Kathryn A., Brooks, Andrew J., Bakkers, Jeroen, Francois, Mathias, Yap, Alpha S., Simons, Cas, Wicking, Carol, Hogan, Benjamin M. and Smith, Kelly A. (2017). Correction to: Tmem2 regulates embryonic Vegf signaling by controlling hyaluronic acid turnover (Developmental Cell 40, 2017, 123-136). Developmental Cell, 40 (4), 421-421. doi: 10.1016/j.devcel.2017.02.005

Correction to: Tmem2 regulates embryonic Vegf signaling by controlling hyaluronic acid turnover (Developmental Cell 40, 2017, 123-136)

2017

Journal Article

Tmem2 regulates embryonic Vegf signaling by controlling hyaluronic acid turnover

De Angelis, Jessica E., Lagendijk, Anne K., Chen, Huijun, Tromp, Alisha, Bower, Neil I., Tunny, Kathryn A., Brooks, Andrew J., Bakkers, Jeroen, Francois, Mathias, Yap, Alpha S., Simons, Cas, Wicking, Carol, Hogan, Benjamin M. and Smith, Kelly A. (2017). Tmem2 regulates embryonic Vegf signaling by controlling hyaluronic acid turnover. Developmental Cell, 40 (2), 123-136. doi: 10.1016/j.devcel.2016.12.017

Tmem2 regulates embryonic Vegf signaling by controlling hyaluronic acid turnover

2017

Journal Article

ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens

Priya, Rashmi, Liang, Xuan, Teo, Jessica L., Duszyc, Kinga, Yap, Alpha S. and Gomez, Guillermo A. (2017). ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens. Molecular Biology of the Cell, 28 (1), 12-20. doi: 10.1091/mbc.E16-04-0262

ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens

2017

Conference Publication

Anillin dependent stabilization of Rho signaling at adherens junctions influences cell extrusion and collective cell migration

Budnar, S., Gomez, G., Naghibosidat, M., Wee, K., Gupta, S., Kambe, H., Verma, S., Hamilton, N., Neufeld, Z. and Yap, A. S. (2017). Anillin dependent stabilization of Rho signaling at adherens junctions influences cell extrusion and collective cell migration. ASCB/EMBO Meeting, Philadelphia Pa United States, 2-6 December 2017. Bethesda, MD United States: American Society for Cell Biology.

Anillin dependent stabilization of Rho signaling at adherens junctions influences cell extrusion and collective cell migration

2017

Other Outputs

Supplementary Figure 1, (e) of the paper Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions.

Priya, Rashmi, Gomez, Guillermo A., Budnar, Srikanth, Verma, Suzie, Cox, Hayley L., Hamilton, Nicholas A. and Yap, Alpha S.K. (2017). Supplementary Figure 1, (e) of the paper Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions.. (Dataset) doi: 10.14264/uql.2017.280

Supplementary Figure 1, (e) of the paper Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions.

2017

Conference Publication

Adherens junctions, force-sensing, and epithelial homeostasis

Yap, Alpha (2017). Adherens junctions, force-sensing, and epithelial homeostasis. Annual Meeting of the American Society for Pharmacology and Experimental Therapeutics (ASPET) at Experimental Biology Meeting, Chicago Il, 22-26 April 2017. Bethesda, MD United States: Federation of American Societies for Experimental Biology.

Adherens junctions, force-sensing, and epithelial homeostasis

2016

Journal Article

Editorial overview: membrane traffic and cell polarity

Bryant, David M. and Yap, Alpha S. (2016). Editorial overview: membrane traffic and cell polarity. Traffic, 17 (12), 1231-1232. doi: 10.1111/tra.12433

Editorial overview: membrane traffic and cell polarity

2016

Journal Article

Contact inhibition of locomotion and mechanical cross-talk between cell-cell and cell-substrate adhesion determine the pattern of junctional tension in epithelial cell aggregates

Coburn, Luke, Lopez, Hender, Caldwell, Benjamin J., Moussa, Elliott, Yap, Chloe, Priya, Rashmi, Noppe, Adrian, Roberts, Anthony P., Lobaskin, Vladimir, Yap, Alpha S., Neufeld, Zoltan and Gomez, Guillermo A. (2016). Contact inhibition of locomotion and mechanical cross-talk between cell-cell and cell-substrate adhesion determine the pattern of junctional tension in epithelial cell aggregates. Molecular Biology of the Cell, 27 (22), 3436-3448. doi: 10.1091/mbc.E16-04-0226

Contact inhibition of locomotion and mechanical cross-talk between cell-cell and cell-substrate adhesion determine the pattern of junctional tension in epithelial cell aggregates

2016

Journal Article

Coronin 1B supports RhoA signaling at cell-cell junctions through myosin II

Priya, Rashmi, Wee, Kenneth, Budnar, Srikanth, Gomez, Guillermo A., Yap, Alpha S. and Michael, Magdalene (2016). Coronin 1B supports RhoA signaling at cell-cell junctions through myosin II. Cell Cycle, 15 (22), 1-9. doi: 10.1080/15384101.2016.1234549

Coronin 1B supports RhoA signaling at cell-cell junctions through myosin II

2016

Journal Article

Resolution of novel pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling

Humphrey, Emily S., Su, Shih-Ping, Nagrial, Adnan M., Hochgraefe, Falko, Pajic, Marina, Lehrbach, Gillian M., Parton, Robert G., Yap, Alpha S., Horvath, Lisa G., Chang, David K., Biankin, Andrew V., Wu, Jianmin and Daly, Roger J. (2016). Resolution of novel pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling. Molecular and Cellular Proteomics, 15 (8), 2671-2685. doi: 10.1074/mcp.M116.058313

Resolution of novel pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling