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2015

Journal Article

Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions

Priya, Rashmi, Gomez, Guillermo A., Budnar, Srikanth, Verma, Suzie, Cox, Hayley L., Hamilton, Nicholas A. and Yap, Alpha S. (2015). Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions. Nature Cell Biology, 17 (10), 1282-1293. doi: 10.1038/ncb3239

Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions

2015

Conference Publication

Time-dependent Deformation or 'Creep' of Viscoelastic Hydrogels Leads to Rac1-dependent Enhanced Spreading, Proliferation, and Differentiation in Human Mesenchymal Stem Cells

Cameron, A., Frith, J., Gomez, G., Yap, A. and Cooper-White, J. (2015). Time-dependent Deformation or 'Creep' of Viscoelastic Hydrogels Leads to Rac1-dependent Enhanced Spreading, Proliferation, and Differentiation in Human Mesenchymal Stem Cells. 4th TERMIS World Congress, Boston Ma, Sep 08-11, 2015. NEW ROCHELLE: MARY ANN LIEBERT, INC.

Time-dependent Deformation or 'Creep' of Viscoelastic Hydrogels Leads to Rac1-dependent Enhanced Spreading, Proliferation, and Differentiation in Human Mesenchymal Stem Cells

2015

Journal Article

Making a choice: how cadherin switching controls cell migration

Priya, Rashmi and Yap, Alpha S. (2015). Making a choice: how cadherin switching controls cell migration. Developmental Cell, 34 (4) 3369, 383-384. doi: 10.1016/j.devcel.2015.08.002

Making a choice: how cadherin switching controls cell migration

2015

Journal Article

Seeing and believing: recent advances in imaging cell-cell interactions

Yap, Alpha S., Michael, Magdalene and Parton, Robert G. (2015). Seeing and believing: recent advances in imaging cell-cell interactions. F1000Research, 4 (F1000 Faculty Rev) 273, 273.1-273.8. doi: 10.12688/f1000research.6435.1

Seeing and believing: recent advances in imaging cell-cell interactions

2015

Journal Article

Mutations in SIPA1L3 cause eye defects through disruption of cell polarity and cytoskeleton organization

Greenlees, Rebecca, Mihelec, Marija, Yousoof, Saira, Speidel, Daniel, Wu, Selwin K., Rinkwitz, Silke, Prokudin, Ivan, Perveen, Rahat, Cheng, Anson, Ma, Alan, Nash, Benjamin, Gillespie, Rachel, Loebel, David A. F., Clayton-Smith, Jill, Lloyd, I. Christopher, Grigg, John R., Tam, Patrick P. L., Yap, Alpha S., Becker, Thomas S., Black, Graeme C. M., Semina, Elena and Jamieson, Robyn V. (2015). Mutations in SIPA1L3 cause eye defects through disruption of cell polarity and cytoskeleton organization. Human Molecular Genetics, 24 (20), 5789-5804. doi: 10.1093/hmg/ddv298

Mutations in SIPA1L3 cause eye defects through disruption of cell polarity and cytoskeleton organization

2015

Journal Article

E-cadherin junctions as active mechanical integrators in tissue dynamics

Lecuit, Thomas and Yap, Alpha S. (2015). E-cadherin junctions as active mechanical integrators in tissue dynamics. Nature Cell Biology, 17 (5), 533-539. doi: 10.1038/ncb3136

E-cadherin junctions as active mechanical integrators in tissue dynamics

2015

Journal Article

An RPTPα/Src family kinase/Rap1 signaling module recruits myosin IIB to support contractile tension at apical E-cadherin junctions

Gomez, Guillermo A., McLachlan, Robert W., Wu, Selwin K., Caldwell, Benjamin J., Moussa, Elliott, Verma, Suzie, Bastiani, Michele, Priya, Rashmi, Parton, Robert G., Gaus, Katharina, Sap, Jan and Yap, Alpha S. (2015). An RPTPα/Src family kinase/Rap1 signaling module recruits myosin IIB to support contractile tension at apical E-cadherin junctions. Molecular Biology of the Cell, 26 (7), 1249-1262. doi: 10.1091/mbc.E14-07-1223

An RPTPα/Src family kinase/Rap1 signaling module recruits myosin IIB to support contractile tension at apical E-cadherin junctions

2015

Journal Article

Vegfc regulates bipotential precursor division and prox1 expression to promote lymphatic identity in zebrafish

Koltowska, Katarzyna, Lagendijk, Anne K., Pichol-Thievend, Cathy, Fischer, Johanna C., Francois, Mathias, Ober, Elke A., Yap, Alpha S. and Hogan, Benjamin M. (2015). Vegfc regulates bipotential precursor division and prox1 expression to promote lymphatic identity in zebrafish. Cell Reports, 13 (9), 1828-1841. doi: 10.1016/j.celrep.2015.10.055

Vegfc regulates bipotential precursor division and prox1 expression to promote lymphatic identity in zebrafish

2015

Journal Article

Activity-driven relaxation of the cortical actomyosin II network synchronizes Munc18-1-dependent neurosecretory vesicle docking

Papadopulos, Andreas, Gomez, Guillermo A., Martin, Sally, Jackson, Jade, Gormal, Rachel S., Keating, Damien J., Yap, Alpha S. and Meunier, Frederic A. (2015). Activity-driven relaxation of the cortical actomyosin II network synchronizes Munc18-1-dependent neurosecretory vesicle docking. Nature Communications, 6 (6297) 6297, 1-11. doi: 10.1038/ncomms7297

Activity-driven relaxation of the cortical actomyosin II network synchronizes Munc18-1-dependent neurosecretory vesicle docking

2015

Journal Article

Active contractility at E-cadherin junctions and its implications for cell extrusion in cancer

Wu, Selwin K., Lagendijk, Anne K., Hogan, Benjamin M., Gomez, Guillermo A. and Yap, Alpha S. (2015). Active contractility at E-cadherin junctions and its implications for cell extrusion in cancer. Cell Cycle, 14 (3), 315-322. doi: 10.4161/15384101.2014.989127

Active contractility at E-cadherin junctions and its implications for cell extrusion in cancer

2015

Journal Article

Current perspectives on cadherin-cytoskeleton interactions and dynamics

Liang, Xuan, Gomez, Guillermo A. and Yap, Alpha S. (2015). Current perspectives on cadherin-cytoskeleton interactions and dynamics. Cell Health and Cytoskeleton, 7, 11-24. doi: 10.2147/CHC.S76107

Current perspectives on cadherin-cytoskeleton interactions and dynamics

2015

Journal Article

Preface

Yap, Alpha S. (2015). Preface. Cellular Adhesion in Development and Disease, 112, XV-XVII. doi: 10.1016/S0070-2153(15)00024-1

Preface

2015

Other Outputs

Network interactions allowing myosin II to feedback to RhoA: sequencing, predictive modelling, and experimentation

Priya, Rashmi, Gomez, Guillermo A., Budnar, Srikanth, Verma, Suzie, Cox, Hayley L., Hamilton, Nicholas A. and Yap, Alpha S.K. (2015). Network interactions allowing myosin II to feedback to RhoA: sequencing, predictive modelling, and experimentation. Macmillan Publishers. (Dataset) doi: 10.14264/uql.2016.825

Network interactions allowing myosin II to feedback to RhoA: sequencing, predictive modelling, and experimentation

2015

Conference Publication

Patterning Rho signaling at the epithelial Zonula Adherens: a tale of feedback loops

Priya, R., Gomez, G. A., Budnar, S., Verma, S., Hamilton, N. A. and Yap, A. S. (2015). Patterning Rho signaling at the epithelial Zonula Adherens: a tale of feedback loops. 2015 Cell Biology ASCB Annual Meeting, San Diego CA, United States, 12-16 December 2015. Bethesda, MD United States: American Society for Cell Biology.

Patterning Rho signaling at the epithelial Zonula Adherens: a tale of feedback loops

2015

Book Chapter

Active Tension: The Role of Cadherin Adhesion and Signaling in Generating Junctional Contractility

Priya, Rashmi and Yap, Alpha S. (2015). Active Tension: The Role of Cadherin Adhesion and Signaling in Generating Junctional Contractility. Cellular Adhesion in Development and Disease. (pp. 65-102) edited by Alpha S. Yap. Maryland Heights, MO United States: Academic Press. doi: 10.1016/bs.ctdb.2014.11.016

Active Tension: The Role of Cadherin Adhesion and Signaling in Generating Junctional Contractility

2015

Conference Publication

RAD51 supports metastasis via three major mechanisms independent of DNA repair

Wiegmans, Adrian P., Ishak, Luke, Yap, Alpha and Khanna, Kum Kum (2015). RAD51 supports metastasis via three major mechanisms independent of DNA repair. 15th International Biennial Congress of the Metastasis Research Society, Heidelberg, Germany, 28 June - 01 July 2014. Amsterdam, The Netherlands: Springer. doi: 10.1007/s10585-015-9708-3

RAD51 supports metastasis via three major mechanisms independent of DNA repair

2015

Book Chapter

Cell-cell adhesion and the cytoskeleton

Acharya, B. R. and Yap, A. S. (2015). Cell-cell adhesion and the cytoskeleton. Encyclopedia of cell biology. (pp. 704-712) edited by Ralph A. Bradshaw and Philip D. Stahl. Kidlington, Oxford, United Kingdom: Elsevier. doi: 10.1016/B978-0-12-394447-4.20068-0

Cell-cell adhesion and the cytoskeleton

2014

Journal Article

Self-organizing actomyosin patterns on the cell cortex of epithelial cell-cell junctions

Moore, Thomas, Wu, Selwin, Michael, Magdalene, Yap, Alpha S.K., Gomez, Guillermo A. and Neufeld, Zoltan (2014). Self-organizing actomyosin patterns on the cell cortex of epithelial cell-cell junctions. Biophysical Journal, 107 (11), 2652-2661. doi: 10.1016/j.bpj.2014.10.045

Self-organizing actomyosin patterns on the cell cortex of epithelial cell-cell junctions

2014

Journal Article

Tropomyosin isoforms support actomyosin biogenesis to generate contractile tension at the epithelial zonula adherens

Caldwell, Benjamin J., Lucas, Christine, Kee, Anthony J., Gaus, Katharina, Gunning, Peter W., Hardeman, Edna C., Yap, Alpha S. and Gomez, Guillermo A. (2014). Tropomyosin isoforms support actomyosin biogenesis to generate contractile tension at the epithelial zonula adherens. Cytoskeleton, 71 (12), 663-676. doi: 10.1002/cm.21202

Tropomyosin isoforms support actomyosin biogenesis to generate contractile tension at the epithelial zonula adherens

2014

Journal Article

Pulsatile contractility of actomyosin networks organizes the cellular cortex at lateral cadherin junctions

Wu, Selwin K., Budnar, Srikanth, Yap, Alpha S. and Gomez, Guillermo A. (2014). Pulsatile contractility of actomyosin networks organizes the cellular cortex at lateral cadherin junctions. European Journal of Cell Biology, 93 (10-12), 396-404. doi: 10.1016/j.ejcb.2014.09.001

Pulsatile contractility of actomyosin networks organizes the cellular cortex at lateral cadherin junctions