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2014

Conference Publication

Disruption of cortical tension patterning drives the outgrowth of oncogenic cells

Wu, S., Gomez, G. A., Michael, M., Verma, S., Cox, H., Lefevre, J. G., Parton, R. G., Hamilton, N. A. and Yap, A. S. (2014). Disruption of cortical tension patterning drives the outgrowth of oncogenic cells. EACR-23: 23rd Biennial Congress of the European Association for Cancer Research, Munich, Germany, 5-8 July 2014. Oxford, United Kingdom: Elsevier. doi: 10.1016/S0959-8049(14)50251-1

Disruption of cortical tension patterning drives the outgrowth of oncogenic cells

2014

Journal Article

RPTPα controls epithelial adherens junctions, linking E-cadherin engagement to c-Src-mediated phosphorylation of cortactin

Truffi, Marta, Dubreuil, Veronique, Liang, Xuan, Vacaresse, Nathalie, Nigon, Fabienne, Han, Siew Ping, Yap, Alpha S., Gomez, Guillermo A. and Sap, Jan (2014). RPTPα controls epithelial adherens junctions, linking E-cadherin engagement to c-Src-mediated phosphorylation of cortactin. Journal of Cell Science, 127 (11), 2420-2432. doi: 10.1242/jcs.134379

RPTPα controls epithelial adherens junctions, linking E-cadherin engagement to c-Src-mediated phosphorylation of cortactin

2013

Journal Article

Patterns in space: coordinating adhesion and actomyosin contractility at E-cadherin junctions

Wu, Selwin Kaixiang and Yap, Alpha S. (2013). Patterns in space: coordinating adhesion and actomyosin contractility at E-cadherin junctions. Cell Communication and Adhesion, 20 (6), 201-212. doi: 10.3109/15419061.2013.856889

Patterns in space: coordinating adhesion and actomyosin contractility at E-cadherin junctions

2013

Journal Article

On giant's shoulders: an interview with Masatoshi Takeichi (RIKEN Centre for Developmental Biology, Kobe)

Yap, Alpha S. and Takeichi, Masatoshi (2013). On giant's shoulders: an interview with Masatoshi Takeichi (RIKEN Centre for Developmental Biology, Kobe). Cell Communication and Adhesion, Early Online (6), 1-3. doi: 10.3109/15419061.2013.854333

On giant's shoulders: an interview with Masatoshi Takeichi (RIKEN Centre for Developmental Biology, Kobe)

2013

Journal Article

E-cadherin supports steady-state Rho signaling at the epithelial zonula adherens

Priya, Rashmi, Yap, Alpha S. and Gomez, Guillermo A. (2013). E-cadherin supports steady-state Rho signaling at the epithelial zonula adherens. Differentiation, 86 (3), 133-140. doi: 10.1016/j.diff.2013.01.002

E-cadherin supports steady-state Rho signaling at the epithelial zonula adherens

2013

Journal Article

A mechanobiological perspective on cadherins and the actin-myosin cytoskeleton

Budnar S. and Yap A.S. (2013). A mechanobiological perspective on cadherins and the actin-myosin cytoskeleton. F1000 Prime Reports, 5 (35) 35, 35.1-35.6. doi: 10.12703/P5-35

A mechanobiological perspective on cadherins and the actin-myosin cytoskeleton

2013

Journal Article

Vinculin, cadherin mechanotransduction and homeostasis of cell-cell junctions

Leerberg, Joanne M. and Yap, Alpha S.K. (2013). Vinculin, cadherin mechanotransduction and homeostasis of cell-cell junctions. Protoplasma, 250 (4), 817-829. doi: 10.1007/s00709-012-0475-6

Vinculin, cadherin mechanotransduction and homeostasis of cell-cell junctions

2013

Journal Article

Dynamic microtubules produce an asymmetric E-cadherin-Bazooka complex to maintain segment boundaries

Bulgakova, Natalia A., Grigoriev, Ilya, Yap, Alpha S., Akhmanova, Anna and Brown, Nicholas H. (2013). Dynamic microtubules produce an asymmetric E-cadherin-Bazooka complex to maintain segment boundaries. Journal of Cell Biology, 201 (6), 887-901. doi: 10.1083/jcb.201211159

Dynamic microtubules produce an asymmetric E-cadherin-Bazooka complex to maintain segment boundaries

2013

Journal Article

The regulation and functional impact of actin assembly at cadherin cell-cell adhesions

Magdalene, Michael and Yap, Alpha S. (2013). The regulation and functional impact of actin assembly at cadherin cell-cell adhesions. Seminars in Cell & Developmental Biology, 24 (4), 298-307. doi: 10.1016/j.semcdb.2012.12.004

The regulation and functional impact of actin assembly at cadherin cell-cell adhesions

2013

Journal Article

An alpha-catenin deja vu

Han, Siew-Ping and Yap, Alpha S. (2013). An alpha-catenin deja vu. Nature Cell Biology, 15 (3), 238-239. doi: 10.1038/ncb2700

An alpha-catenin deja vu

2013

Journal Article

Cadherin junctions and their cytoskeleton(s)

Brieher, William M. and Yap, Alpha S. (2013). Cadherin junctions and their cytoskeleton(s). Current Opinion in Cell Biology, 25 (1), 39-46. doi: 10.1016/j.ceb.2012.10.010

Cadherin junctions and their cytoskeleton(s)

2013

Book Chapter

Coordinating Rho and Rac: the regulation of Rho GTPase signaling and cadherin junctions

Ratheesh, Aparna, Priya, Rashmi and Yap, Alpha S. (2013). Coordinating Rho and Rac: the regulation of Rho GTPase signaling and cadherin junctions. Progress in molecular biology and translational science: the molecular biology of cadherins. (pp. 49-68) edited by Frans Van Roy. London, United Kingdom: Academic Press (Elsevier). doi: 10.1016/B978-0-12-394311-8.00003-0

Coordinating Rho and Rac: the regulation of Rho GTPase signaling and cadherin junctions

2012

Journal Article

A WAVE2-Arp2/3 actin nucleator apparatus supports junctional tension at the epithelial zonula adherens

Verma, Suzie, Han, Siew Ping, Michael, Magdalene, Gomez, Guillermo, Yang, Zhe, Teasdale, Rohan D., Ratheesh, Aparna, Kovacs, Eva M., Ali, Radiya G. and Yap, Alpha S.K. (2012). A WAVE2-Arp2/3 actin nucleator apparatus supports junctional tension at the epithelial zonula adherens. Molecular Biology of The Cell, 23 (23), 4601-4610. doi: 10.1091/mbc.E12-08-0574

A WAVE2-Arp2/3 actin nucleator apparatus supports junctional tension at the epithelial zonula adherens

2012

Journal Article

A bigger picture: classical cadherins and the dynamic actin cytoskeleton

Ratheesh, Aparna and Yap, Alpha S. (2012). A bigger picture: classical cadherins and the dynamic actin cytoskeleton. Nature Reviews Molecular Cell Biology, 13 (10), 673-679. doi: 10.1038/nrm3431

A bigger picture: classical cadherins and the dynamic actin cytoskeleton

2012

Journal Article

The juxtamembrane domain of the E-cadherin cytoplasmic tail contributes to its interaction with Myosin VI

Mangold, Sabine, Norwood, Suzanne J., Yap, Alpha S and Collins, Brett M. (2012). The juxtamembrane domain of the E-cadherin cytoplasmic tail contributes to its interaction with Myosin VI. BioArchitecture, 2 (5), 185-188. doi: 10.4161/bioa.22082

The juxtamembrane domain of the E-cadherin cytoplasmic tail contributes to its interaction with Myosin VI

2012

Journal Article

Centralspindlin and α-catenin regulate Rho signalling at the epithelial zonula adherens

Ratheesh, Aparna, Gomez, Guillermo A., Priya, Rashmi, Verma, Suzie, Kovacs, Eva M., Jiang, Kai, Brown, Nicholas H., Akhmanova, Anna, Stehbens, Samantha J. and Yap, Alpha S. (2012). Centralspindlin and α-catenin regulate Rho signalling at the epithelial zonula adherens. Nature Cell Biology, 14 (8), 818-828. doi: 10.1038/ncb2532

Centralspindlin and α-catenin regulate Rho signalling at the epithelial zonula adherens

2012

Journal Article

Contact inhibition (of proliferation) redux

McClatchey, Andrea I. and Yap, Alpha S. K. (2012). Contact inhibition (of proliferation) redux. Current Opinion in Cell Biology, 423-424 (5), 685-694. doi: 10.1016/j.ceb.2012.06.009

Contact inhibition (of proliferation) redux

2012

Book Chapter

The cytoskeleton and classical cadherin adhesions

Han, Siew Ping and Yap, Alpha S. (2012). The cytoskeleton and classical cadherin adhesions. Adherens junctions: From molecular mechanisms to tissue development and disease. (pp. 111-135) edited by Tony Harris. Dordrecht, Netherlands: Springer. doi: 10.1007/978-94-007-4186-7_6

The cytoskeleton and classical cadherin adhesions

2011

Journal Article

Productive tension: Force-sensing and homeostasis of cell-cell junctions

Gomez, Guillermo A., McLachlan, Robert W. and Yap, Alpha S. (2011). Productive tension: Force-sensing and homeostasis of cell-cell junctions. Trends in Cell Biology, 21 (9), 499-505. doi: 10.1016/j.tcb.2011.05.006

Productive tension: Force-sensing and homeostasis of cell-cell junctions

2011

Journal Article

N-WASP regulates the epithelial junctional actin cytoskeleton through a non-canonical post-nucleation pathway

Kovacs, Eva M., Verma, Suzie, Ali, Radiy G., Ratheesh, Aparna, Hamilton, Nicholas A., Akhmanova, Anna and Yap, Alpha S. (2011). N-WASP regulates the epithelial junctional actin cytoskeleton through a non-canonical post-nucleation pathway. Nature Cell Biology, 13 (8), 934-943. doi: 10.1038/ncb2290

N-WASP regulates the epithelial junctional actin cytoskeleton through a non-canonical post-nucleation pathway