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2015 Conference Publication Profiling at the Single-Cell Level Reveals Evidence for Antigen-Driven Oligoclonal Expansion of Citrullinated Vimentin-Specific CD4+T Cells in Peripheral Blood of Rheumatoid Arthritis (RA) PatientsLaw, Soi Cheng, Nel, Hendrik, Rossjohn, Jamie, Reid, Hugh H., La Gruta, Nicole L. and Thomas, Ranjeny (2015). Profiling at the Single-Cell Level Reveals Evidence for Antigen-Driven Oligoclonal Expansion of Citrullinated Vimentin-Specific CD4+T Cells in Peripheral Blood of Rheumatoid Arthritis (RA) Patients. Annual Meeting of the American-College-of-Rheumatology (ACR) and Association-of-Rheumatology-Health-Professionals (ARHP), San Francisco Ca, Nov 06-11, 2015. HOBOKEN: WILEY-BLACKWELL. |
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2015 Conference Publication The Shared Rheumatoid Arthritis HLA-DRB1 Susceptibility Epitope Shapes the Molecular Orientation of Citrulline and the Autoreactive T Cell Receptor Repertoirevan Heemst, Jurgen, Scally, Stephen, Law, Soi Cheng, van der Woude, Diane, Hitchon, Carol, Robinson, David B., Huizinga, T. W. J., Reid, Hugh H., Toes, Rene E. M., El-Gabalawy, Hani, Rossjohn, Jamie and Thomas, Ranjeny (2015). The Shared Rheumatoid Arthritis HLA-DRB1 Susceptibility Epitope Shapes the Molecular Orientation of Citrulline and the Autoreactive T Cell Receptor Repertoire. Annual Meeting of the American-College-of-Rheumatology (ACR) and Association-of-Rheumatology-Health-Professionals (ARHP), San Francisco Ca, Nov 06-11, 2015. HOBOKEN: WILEY-BLACKWELL. |
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2015 Journal Article Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patientsBenham, Helen, Nel, Hendrik J., Law, Soi Cheng, Mehdi, Ahmed M., Street, Shayna, Ramnoruth, Nishta, Pahau, Helen, Lee, Bernett T., Ng, Jennifer, Brunck, Marion E. G., Hyde, Claire, Trouw, Leendert A., Dudek, Nadine L., Purcell, Anthony W., O'Sullivan, Brendan J., Connolly, John E., Paul, Sanjoy K., Le Cao, Kim-Anh and Thomas, Ranjeny (2015). Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients. Science Translational Medicine, 7 (290) 290ra87, 290ra87.1-290ra87.11. doi: 10.1126/scitranslmed.aaa9301 |
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2015 Conference Publication Profiling the TCR repertoire in the Rheumatoid Arthritis (RA) Autoantigen-Specific Cd4+T-Cells At the Single-Cell LevelLaw, S., Rossjohn, J., Nel, H., La Gruta, N., Reid, H. and Thomas, R. (2015). Profiling the TCR repertoire in the Rheumatoid Arthritis (RA) Autoantigen-Specific Cd4+T-Cells At the Single-Cell Level. Australian Rheumatology Associationin conjunction with Rheumatology Health Professionals Association, 56th Annual Scientific Meeting, Adelaide, South Australia, 23–26 May 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/imj.12752 |
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2014 Journal Article Identification of Self-antigen-specific T Cells Reflecting Loss of Tolerance in Autoimmune Disease Underpins Preventative Immunotherapeutic Strategies in Rheumatoid ArthritisLaw, Soi-Chen, Benham, Helen, Reid, Hugh H., Rossjohn, Jamie and Thomas, Ranjeny (2014). Identification of Self-antigen-specific T Cells Reflecting Loss of Tolerance in Autoimmune Disease Underpins Preventative Immunotherapeutic Strategies in Rheumatoid Arthritis. Rheumatic Disease Clinics of North America, 40 (4), 735-752. doi: 10.1016/j.rdc.2014.07.015 |
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2014 Conference Publication Multiple Mechanisms of Tolerance Characterize the Immune Response to Autologous Modified Dendritic Cells Exposed to Citrullinated Peptides in Patients with Rheumatoid Arthritis.Law, Soi-Cheng, Nel, Hendrik, Mehdi, Ahmed, Le Cao, Kim-Anh and Thomas, Ranjeny (2014). Multiple Mechanisms of Tolerance Characterize the Immune Response to Autologous Modified Dendritic Cells Exposed to Citrullinated Peptides in Patients with Rheumatoid Arthritis.. 2014 ACR/ARHP Annual Meeting, Boston, MA United States, 14-19 November 2014. Hoboken, NJ United States: John Wiley and Sons. doi: 10.1002/art.38914 |
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2013 Journal Article A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritisScally, Stephen W., Petersen, Jan, Law, Soi Cheng, Dudek, Nadine L., Nel, Hendrik J., Loh, Khai Lee, Wijeyewickrema, Lakshmi C., Eckle, Sidonia B.G., van Heemst, Jurgen, Pike, Robert N., McCluskey, James, Toes, Rene E., La Gruta, Nicole L., Purcell, Anthony W., Reid, Hugh H., Thomas, Ranjeny and Rossjohn, Jamie (2013). A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis. Journal of Experimental Medicine, 210 (12), 2569-2582. doi: 10.1084/jem.20131241 |
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2012 Journal Article T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope allelesLaw, Soi Cheng, Street, Shayna, Yu, Chien-Hsiung Alan, Capini, Christelle, Ramnoruth, Sakoontalla, Nel, Hendrik J., van Gorp, Eline, Hyde, Claire, Lau, Kim, Pahau, Helen, Purcell, Anthony W. and Thomas, Ranjeny (2012). T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles. Arthritis Research and Therapy, 14 (3) R118, R118.1-R118.12. doi: 10.1186/ar3848 |
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2012 Conference Publication Outcome of a phase I trial of rheumavax in patients with rheumatoid arthritisNel, H., Law, S., Street, S., Ramnoruth, N., Shams, R., Pahau, H., Brunck, M., Hyde, C., O'Sullivan, B., Capini, C., Tran, A., Ng, J., Godfrey, D. and Thomas, R. (2012). Outcome of a phase I trial of rheumavax in patients with rheumatoid arthritis. 53rd Annual Scientific Meeting of the Australian Rheumatology Association in conjunction with Rheumatology Health Professionals, Canberra ACT, Australia, 12-15 May 2012. Richmond Vic., Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1445-5994.2012.02761.x |
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2011 Conference Publication PROINFLAMMATORY AND REGULATORY T CELL RESPONSES TO CITRULLINATED AUTOANTIGENIC PEPTIDES IN PERIPHERAL BLOOD OF SHARED EPITOPE plus RHEUMATOID ARTHRITIS PATIENTSStreet, S., Purcell, A., Law, S., Yu, A., Capini, C., O'Sullivan, B., Pahau, H. and Thomas, R. (2011). PROINFLAMMATORY AND REGULATORY T CELL RESPONSES TO CITRULLINATED AUTOANTIGENIC PEPTIDES IN PERIPHERAL BLOOD OF SHARED EPITOPE plus RHEUMATOID ARTHRITIS PATIENTS. MALDEN: WILEY-BLACKWELL. |
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2011 Conference Publication Feasibility, safety and clinical effects of a single intradermal administration of autologous tolerising dendritic cells exposed to citrullinated peptides in patients with rheumatoid arthritisThomas, Ranjeny, Street, Shayna, Ramnoruth, Nishta, Pahau, Helen, Law, Soi, Brunck, Marion, Hyde, Claire, O'Sullivan, Brendan, Capini, C., Tran, A., Ng, J. and Paul, S. (2011). Feasibility, safety and clinical effects of a single intradermal administration of autologous tolerising dendritic cells exposed to citrullinated peptides in patients with rheumatoid arthritis. 75th Annual Scientific Meeting of the American College of Rheumatology/46th Annual Scientific Meeting of the Association-of-Rheumatology-Health-Professionals, Chicago, IL, United States, 04-09 November 2011. Hoboken NJ, United States: John Wiley & Sons. doi: 10.1002/art.33310 |
