2022 Journal Article A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant inhibitory impact on CSF1R signallingStables, Jennifer, Green, Emma K., Sehgal, Anuj, Patkar, Omkar L., Keshvari, Sahar, Taylor, Isis, Ashcroft, Maisie E., Grabert, Kathleen, Wollscheid-Lengeling, Evi, Szymkowiak, Stefan, McColl, Barry W., Adamson, Antony, Humphreys, Neil E., Mueller, Werner, Starobova, Hana, Vetter, Irina, Shabestari, Sepideh Kiani, Blurton-Jones, Matthew M., Summers, Kim M., Irvine, Katharine M., Pridans, Clare and Hume, David A. (2022). A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant inhibitory impact on CSF1R signalling. Development, 149 (8) dev200237. doi: 10.1242/dev.200237 |
2022 Other Outputs Glucocorticoid activity regulates glucocorticoid receptor isoform expression and downstream gene transcription in humansLockett, Jack , Saif, Zarqa, Nolan, Brendan J., Keshvari, Sahar, Cesana-Nigro, Nicole, Ewing, Adam, Inder, Warrick J. and Clifton, Vicki L. (2022). Glucocorticoid activity regulates glucocorticoid receptor isoform expression and downstream gene transcription in humans. The University of Queensland. (Dataset) doi: 10.48610/ee0c38e |
2022 Journal Article Therapeutic potential of macrophage colony-stimulating factor (CSF1) in chronic liver diseaseKeshvari, Sahar, Genz, Berit, Teakle, Ngari, Caruso, Melanie, Cestari, Michelle F., Patkar, Omkar L., Tse, Brian W. C., Sokolowski, Kamil A., Ebersbach, Hilmar, Jascur, Julia, MacDonald, Kelli P. A., Miller, Gregory, Ramm, Grant A., Pettit, Allison R., Clouston, Andrew D., Powell, Elizabeth E., Hume, David A. and Irvine, Katharine M. (2022). Therapeutic potential of macrophage colony-stimulating factor (CSF1) in chronic liver disease. Disease Models and Mechanisms, 15 (4) dmm049387, 1-15. doi: 10.1242/dmm.049387 |
2021 Journal Article Pre-Diabetes Increases Tuberculosis Disease Severity, While High Body Fat Without Impaired Glucose Tolerance Is ProtectiveSinha, Roma, Ngo, Minh Dao, Bartlett, Stacey, Bielefeldt-Ohmann, Helle, Keshvari, Sahar, Hasnain, Sumaira Z., Donovan, Meg L., Kling, Jessica C., Blumenthal, Antje, Chen, Chen, Short, Kirsty R. and Ronacher, Katharina (2021). Pre-Diabetes Increases Tuberculosis Disease Severity, While High Body Fat Without Impaired Glucose Tolerance Is Protective. Frontiers in Cellular and Infection Microbiology, 11 691823, 691823. doi: 10.3389/fcimb.2021.691823 |
2021 Journal Article CSF1R-dependent macrophages control postnatal somatic growth and organ maturationKeshvari, Sahar, Caruso, Melanie, Teakle, Ngari, Batoon, Lena, Sehgal, Anuj, Patkar, Omkar L., Ferrari-Cestari, Michelle, Snell, Cameron E., Chen, Chen, Stevenson, Alex, Davis, Felicity M., Bush, Stephen J., Pridans, Clare, Summers, Kim M., Pettit, Allison R., Irvine, Katharine M. and Hume, David A. (2021). CSF1R-dependent macrophages control postnatal somatic growth and organ maturation. PLoS Genetics, 17 (6) e1009605, e1009605. doi: 10.1371/journal.pgen.1009605 |
2021 Journal Article The mononuclear phagocyte system of the ratHume, David A., Caruso, Melanie, Keshvari, Sahar, Patkar, Omkar L., Sehgal, Anuj, Bush, Stephen J., Summers, Kim M., Pridans, Clare and Irvine, Katharine M. (2021). The mononuclear phagocyte system of the rat. The Journal of Immunology, 206 (10), 2251-2263. doi: 10.4049/jimmunol.2100136 |
2021 Journal Article Ex vivo glucocorticoid-induced secreted proteome approach for discovery of glucocorticoid-responsive proteins in human serumInder, Warrick J., Mohamed, Ahmed, Keshvari, Sahar, Barclay, Johanna L., Ruelcke, Jayde E., Stoll, Thomas, Nolan, Brendan J., Cesana-Nigro, Nicole and Hill, Michelle M. (2021). Ex vivo glucocorticoid-induced secreted proteome approach for discovery of glucocorticoid-responsive proteins in human serum. Proteomics - Clinical Applications, 15 (2-3) 2000078, 2000078. doi: 10.1002/prca.202000078 |
2021 Journal Article Analysis of homozygous and heterozygous Csf1r knockout in the rat as a model for understanding microglial function in brain development and the impacts of human CSF1R mutationsPatkar, Omkar L., Caruso, Melanie, Teakle, Ngari, Keshvari, Sahar, Bush, Stephen J., Pridans, Clare, Belmer, Arnauld, Summers, Kim M., Irvine, Katharine M. and Hume, David A. (2021). Analysis of homozygous and heterozygous Csf1r knockout in the rat as a model for understanding microglial function in brain development and the impacts of human CSF1R mutations. Neurobiology of Disease, 151 105268, 105268. doi: 10.1016/j.nbd.2021.105268 |
2019 Journal Article The effect of glucocorticoids on Thrombospondin-1, Osteocalcin and the Thrombospondin-1:Osteocalcin ratio in humansCesana-Nigro, Nicole, Keshvari, Sahar, Barclay, Johanna L., Sorbello, Jane, Upham, John W., Benham, Helen, Anderson, Stephen T., Steiger, Natasha, Prins, Johannes B. and Inder, Warrick J. (2019). The effect of glucocorticoids on Thrombospondin-1, Osteocalcin and the Thrombospondin-1:Osteocalcin ratio in humans. Clinical Endocrinology, 91 (6) cen.14108, 728-736. doi: 10.1111/cen.14108 |
2019 Journal Article Analysis of the impact of CSF‐1 administration in adult rats using a novel Csf1r ‐mApple reporter geneIrvine, Katharine M., Caruso, Melanie, Cestari, Michelle Ferrari, Davis, Gemma M., Keshvari, Sahar, Sehgal, Anuj, Pridans, Clare and Hume, David A. (2019). Analysis of the impact of CSF‐1 administration in adult rats using a novel Csf1r ‐mApple reporter gene. Journal of Leukocyte Biology, 107 (2) JLB.MA0519-149R, 221-235. doi: 10.1002/jlb.ma0519-149r |
2018 Conference Publication Body composition to estimate percentage fat mass: comparisons between common clinical methods and gold-standard air displacement plethysmography (BODPOD) in a cohort of university studentsAkison, Lisa K., Gallo, Linda A., Barclay, Johanna L., Burgess, Danielle, Keshvari, Sahar, Fotheringham, Amelia K. and Moritz, Karen M. (2018). Body composition to estimate percentage fat mass: comparisons between common clinical methods and gold-standard air displacement plethysmography (BODPOD) in a cohort of university students. Joint Annual Scientific Meetings of Endocrine Society of Australia (ESA) and Society for Reproductive Biology (SRB), Perth, Australia, 27-30 August 2017. Chichester, West Sussex, United Kingdom: Wiley-Blackwell. |
2017 Journal Article Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunctionBorg, Danielle J., Yap, Felicia Y. T., Keshvari, Sahar, Simmons, David G., Gallo, Linda A., Fotheringham, Amelia K., Zhuang, Aowen, Slattery, Robyn M., Hasnain, Sumaira Z., Coughlan, Melinda T., Kantharidis, Phillip and Forbes, Josephine M. (2017). Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction. Islets, 10 (1), 10-24. doi: 10.1080/19382014.2017.1405189 |
2017 Journal Article Evolution of the magic bullet: Single chain antibody fragments for the targeted delivery of immunomodulatory proteinsFercher, Christian, Keshvari, Sahar, McGuckin, Michael A and Barnard, Ross T (2017). Evolution of the magic bullet: Single chain antibody fragments for the targeted delivery of immunomodulatory proteins. Experimental biology and medicine (Maywood, N.J.), 243 (2), 166-183. doi: 10.1177/1535370217748575 |
2017 Journal Article Muscle-specific overexpression of AdipoR1 or AdipoR2 gives rise to common and discrete local effects whilst AdipoR2 promotes additional systemic effectsKeshvari, Sahar, Henstridge, Darren C., Ng, Choaping, Febbraio, Mark A. and Whitehead, Jonathan P. (2017). Muscle-specific overexpression of AdipoR1 or AdipoR2 gives rise to common and discrete local effects whilst AdipoR2 promotes additional systemic effects. Scientific Reports, 7 (1) 41792, 41792. doi: 10.1038/srep41792 |
2016 Other Outputs Molecular characterisation of the adiponectin receptors, AdipoR1 and AdipoR2Keshvari, Sahar (2016). Molecular characterisation of the adiponectin receptors, AdipoR1 and AdipoR2. PhD Thesis, School of Medicine, The University of Queensland. doi: 10.14264/uql.2016.782 |
2016 Journal Article Development of an enzyme-linked immunosorbent assay for thrombospondin-1 and comparison of human plasma and serum concentrationsBarclay, Johanna L., Keshvari, Sahar, Whitehead, Jonathan P. and Inder, Warrick J. (2016). Development of an enzyme-linked immunosorbent assay for thrombospondin-1 and comparison of human plasma and serum concentrations. Annals of Clinical Biochemistry, 53 (5), 606-610. doi: 10.1177/0004563216628891 |
2016 Journal Article Effects of delayed sample processing on determination of total and high molecular weight (HMW) adiponectin in serum and plasma: a pilot studyNg, Choaping, Rose, Felicity J., Keshvari, Sahar, Reeves, Marina M., Dimeski, Goce, Hickman, Ingrid J. and Whitehead, Jonathan P. (2016). Effects of delayed sample processing on determination of total and high molecular weight (HMW) adiponectin in serum and plasma: a pilot study. International Journal of Chemistry, 8 (3), 19-24. doi: 10.5539/ijc.v8n3p19 |
2016 Journal Article Identification of carboxypeptidase X (CPX)-1 as a positive regulator of adipogenesisKim, Yu-Hee, Barclay, Johanna L., He, Jingjing, Luo, Xiao, O'Neill, Hayley M., Keshvari, Sahar, Webster, Julie A., Ng, Choaping, Hutley, Louise J., Prins, Johannes B. and Whitehead, Jonathan P. (2016). Identification of carboxypeptidase X (CPX)-1 as a positive regulator of adipogenesis. FASEB Journal, 30 (7), 2528-2540. doi: 10.1096/fj.201500107R |
2016 Journal Article Thrombospondin-1 is a glucocorticoid responsive protein in humansBarclay, Johanna L., Petersons, Carolyn J., Keshvari, Sahar, Sorbello, Jane, Mangelsdorf, Brenda L., Thompson, Campbell H., Prins, Johannes B., Burt, Morton G., Whitehead, Jonathan P. and Inder, Warrick J. (2016). Thrombospondin-1 is a glucocorticoid responsive protein in humans. European Journal of Endocrinology, 174 (2), 193-201. doi: 10.1530/EJE-15-0964 |
2016 Conference Publication Chronic treatment with cobalt protoporphyrin or hemin compromises adipogenesis and adiponectin production in a manner indenpendent of heme-oxygenase-1Yang, M., Kimura, M., Ng, C., Keshvari, S., He, J., Barclay, J. L. and Whitehead, J. P. (2016). Chronic treatment with cobalt protoporphyrin or hemin compromises adipogenesis and adiponectin production in a manner indenpendent of heme-oxygenase-1. 52nd Annual Meeting of the European Association for the Study of Diabetes (EASD), Munich, Germany, Sep 12-16, 2016. Heidelberg, Germany: Springer. doi: 10.1007/s00125-016-4046-9 |