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2024

Journal Article

Adaptive microtubule reinforcement enables cell migration through 3D environments

Ju, Robert J. and Stehbens, Samantha J. (2024). Adaptive microtubule reinforcement enables cell migration through 3D environments. Nature Cell Biology. doi: 10.1038/s41556-024-01477-w

Adaptive microtubule reinforcement enables cell migration through 3D environments

2024

Journal Article

Compression-dependent microtubule reinforcement enables cells to navigate confined environments

Ju, Robert J., Falconer, Alistair D., Schmidt, Christanny J., Martinez, Marco A. Enriquez, Dean, Kevin M., Fiolka, Reto P., Sester, David P., Nobis, Max, Timpson, Paul, Lomakin, Alexis J., Danuser, Gaudenz, White, Melanie D., Haass, Nikolas K., Oelz, Dietmar B. and Stehbens, Samantha J. (2024). Compression-dependent microtubule reinforcement enables cells to navigate confined environments. Nature Cell Biology. doi: 10.1038/s41556-024-01476-x

Compression-dependent microtubule reinforcement enables cells to navigate confined environments

2024

Journal Article

c-Src induced vascular malformations require localised matrix degradation at focal adhesions

Essebier, Patricia, Keyser, Mikaela, Yordanov, Teodor, Hill, Brittany, Yu, Alexander, Noordstra, Ivar, Yap, Alpha S., Stehbens, Samantha J., Lagendijk, Anne K., Schimmel, Lilian and Gordon, Emma J. (2024). c-Src induced vascular malformations require localised matrix degradation at focal adhesions. Journal of Cell Science, 137 (13) jcs262101. doi: 10.1242/jcs.262101

c-Src induced vascular malformations require localised matrix degradation at focal adhesions

2024

Journal Article

Perspectives in collective cell migration – moving forward

Stehbens, Samantha J., Scarpa, Elena and White, Melanie D. (2024). Perspectives in collective cell migration – moving forward. Journal of Cell Science, 137 (12) jcs261549. doi: 10.1242/jcs.261549

Perspectives in collective cell migration – moving forward

2024

Conference Publication

Uncovering Microtubule-driven Mechanisms of Melanoma Invasion

Ju, R. J., Falconer, A. D., Dean, K. M., Fiolka, R. P., Sester, D. P., Nobis, M., Timpson, P., Lomakin, A. J., Danuser, G., White, M. D., Oelz, D. B., Haass, N. K. and Stehbens, S. J. (2024). Uncovering Microtubule-driven Mechanisms of Melanoma Invasion. 50th Annual Meeting of the Dermatological Research Working Group (ADF), Dusseldorf, Germany, 6-9 March 2024. Chichester, West Sussex United Kingdom: Wiley-Blackwell.

Uncovering Microtubule-driven Mechanisms of Melanoma Invasion

2024

Journal Article

Hyaluronic acid turnover controls the severity of cerebral cavernous malformations in bioengineered human micro-vessels

Yordanov, Teodor E., Keyser, Mikaela S., Enriquez Martinez, Marco A., Esposito, Tyron, Tefft, Juliann B., Morris, Elysse K., Labzin, Larisa I., Stehbens, Samantha J., Rowan, Alan E., Hogan, Benjamin M., Chen, Christopher S., Lauko, Jan and Lagendijk, Anne K. (2024). Hyaluronic acid turnover controls the severity of cerebral cavernous malformations in bioengineered human micro-vessels. APL Bioengineering, 8 (1) 016108, 016108. doi: 10.1063/5.0159330

Hyaluronic acid turnover controls the severity of cerebral cavernous malformations in bioengineered human micro-vessels

2024

Journal Article

Microtubule control of migration: Coordination in confinement

Schmidt, Christanny J. and Stehbens, Samantha J. (2024). Microtubule control of migration: Coordination in confinement. Current Opinion in Cell Biology, 86 102289, 102289. doi: 10.1016/j.ceb.2023.102289

Microtubule control of migration: Coordination in confinement

2024

Journal Article

Dysregulation of tyrosinase activity: a potential link between skin disorders and neurodegeneration

Jin, Wanli, Stehbens, Samantha J., Barnard, Ross T., Blaskovich, Mark A. T. and Ziora, Zyta M. (2024). Dysregulation of tyrosinase activity: a potential link between skin disorders and neurodegeneration. Journal of Pharmacy and Pharmacology, 76 (1), 13-22. doi: 10.1093/jpp/rgad107

Dysregulation of tyrosinase activity: a potential link between skin disorders and neurodegeneration

2023

Conference Publication

Uncovering Dynamic Changes In Medulloblastoma Associated Vasculature In Zebrafish

Morris, Elysse, Daignault-Mill, Sheena, Ju, Robert J., da Silva, Jason, Gordon, Emma, Wainwright, Brandon, Stehbens, Samantha, Genovesi, Laura and Lagendijk, Anne (2023). Uncovering Dynamic Changes In Medulloblastoma Associated Vasculature In Zebrafish. 2023 Pediatric Neuro-Oncology Research Conference, Washington, DC United States, 22-24 June 2023. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/neuonc/noad073.274

Uncovering Dynamic Changes In Medulloblastoma Associated Vasculature In Zebrafish

2023

Journal Article

Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function

Jami, Sina, Deuis, Jennifer R., Klasfauseweh, Tabea, Cheng, Xiaoyang, Kurdyukov, Sergey, Chung, Felicity, Okorokov, Andrei L., Li, Shengnan, Zhang, Jiangtao, Cristofori-Armstrong, Ben, Israel, Mathilde R., Ju, Robert J., Robinson, Samuel D., Zhao, Peng, Ragnarsson, Lotten, Andersson, Åsa, Tran, Poanna, Schendel, Vanessa, McMahon, Kirsten L., Tran, Hue N. T., Chin, Yanni K.-Y., Zhu, Yifei, Liu, Junyu, Crawford, Theo, Purushothamvasan, Saipriyaa, Habib, Abdella M., Andersson, David A., Rash, Lachlan D., Wood, John N. ... Vetter, Irina (2023). Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function. Nature Communications, 14 (1) 2442. doi: 10.1038/s41467-023-37963-2

Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function

2023

Conference Publication

Bortezomib induces immunogenic cell death in melanoma and enhances immune response in vivo

Daignault, S., Ju, R. J., Spoerri, L., Stehbens, S. J., Hill, D. S., Dolcetti, R. and Haass, N. (2023). Bortezomib induces immunogenic cell death in melanoma and enhances immune response in vivo. Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF), Berlin, Germany, 11-14 March 2020. Chichester, West Sussex United Kingdom: Wiley-Blackwell.

Bortezomib induces immunogenic cell death in melanoma and enhances immune response in vivo

2023

Conference Publication

MITF-mediated changes of tumour architecture, tensile stress and in extracellular matrix (ECM) control intratumour heterogeneity in melanoma

Spoerri, L., Tonnessen-Murray, C. A., Beaumont, K. A., Hill, D. S., Jurek, R. J., Gunasingh, G., Vanwalleghem, G., Daignault, S., Fane, M. E., Schaider, H., Smith, A., Stehbens, S. J., Weninger, W., Scott, E. E., Gabrielli, B. and Haass, N. (2023). MITF-mediated changes of tumour architecture, tensile stress and in extracellular matrix (ECM) control intratumour heterogeneity in melanoma. Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF), Berlin, Germany, 11-14 March 2020. Chichester, West Sussex United Kingdom: Wiley-Blackwell.

MITF-mediated changes of tumour architecture, tensile stress and in extracellular matrix (ECM) control intratumour heterogeneity in melanoma

2023

Conference Publication

Uncovering biomechanically regulated cellular processes of melanoma cell invasion and survival in confined environments

Ju, R. J., Chhabra, Y., Stehbens, S. J. and Haass, N. (2023). Uncovering biomechanically regulated cellular processes of melanoma cell invasion and survival in confined environments. Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF), Berlin, Germany, 11-14 March 2020. Chichester, West Sussex United Kingdom: Wiley-Blackwell.

Uncovering biomechanically regulated cellular processes of melanoma cell invasion and survival in confined environments

2023

Journal Article

Addressing blood-brain-tumor-barrier heterogeneity in pediatric brain tumors with innovative preclinical models

Morris, Elysse K., Daignault-Mill, Sheena, Stehbens, Samantha J., Genovesi, Laura A. and Lagendijk, Anne K. (2023). Addressing blood-brain-tumor-barrier heterogeneity in pediatric brain tumors with innovative preclinical models. Frontiers in Oncology, 13 1101522, 1-9. doi: 10.3389/fonc.2023.1101522

Addressing blood-brain-tumor-barrier heterogeneity in pediatric brain tumors with innovative preclinical models

2022

Journal Article

Editorial: Forces in biology - Cell and developmental mechanobiology and its implications in disease - Volume II

Wu, Selwin K., Gomez, Guillermo A., Stehbens, Samantha, Acharya, Bipul R., Ratheesh, Aparna, Priya, Rashmi, Lagendijk, Anne and Bershadsky, Alexander (2022). Editorial: Forces in biology - Cell and developmental mechanobiology and its implications in disease - Volume II. Frontiers in Cell and Developmental Biology, 10 1082857, 1082857. doi: 10.3389/fcell.2022.1082857

Editorial: Forces in biology - Cell and developmental mechanobiology and its implications in disease - Volume II

2022

Journal Article

Persister state-directed transitioning and vulnerability in melanoma

Chauvistré, Heike, Shannan, Batool, Daignault-Mill, Sheena M., Ju, Robert J., Picard, Daniel, Egetemaier, Stefanie, Váraljai, Renáta, Gibhardt, Christine S., Sechi, Antonio, Kaschani, Farnusch, Keminer, Oliver, Stehbens, Samantha J., Liu, Qin, Yin, Xiangfan, Jeyakumar, Kirujan, Vogel, Felix C. E., Krepler, Clemens, Rebecca, Vito W., Kubat, Linda, Lueong, Smiths S., Forster, Jan, Horn, Susanne, Remke, Marc, Ehrmann, Michael, Paschen, Annette, Becker, Jürgen C., Helfrich, Iris, Rauh, Daniel, Kaiser, Markus ... Roesch, Alexander (2022). Persister state-directed transitioning and vulnerability in melanoma. Nature Communications, 13 (1) 3055, 3055. doi: 10.1038/s41467-022-30641-9

Persister state-directed transitioning and vulnerability in melanoma

2022

Journal Article

The deterioration of calcified cartilage integrity reflects the severity of osteoarthritis—A structural, molecular, and biochemical analysis

Fan, Xiwei, Wu, Xiaoxin, Trevisan Franca De Lima, Lucas, Stehbens, Samantha, Punyadeera, Chamindie, Webb, Richard, Hamilton, Brett, Ayyapann, Vijay, McLauchlan, Connor, Crawford, Ross, Zheng, Minghao, Xiao, Yin and Prasadam, Indira (2022). The deterioration of calcified cartilage integrity reflects the severity of osteoarthritis—A structural, molecular, and biochemical analysis. FASEB Journal, 36 (2) e22142, 1-18. doi: 10.1096/fj.202101449R

The deterioration of calcified cartilage integrity reflects the severity of osteoarthritis—A structural, molecular, and biochemical analysis

2021

Journal Article

Collagen polarization promotes epithelial elongation by stimulating locoregional cell proliferation

Katsuno-Kambe, Hiroko, Teo, Jessica L., Ju, Robert J., Hudson, James, Stehbens, Samantha J. and Yap, Alpha S. (2021). Collagen polarization promotes epithelial elongation by stimulating locoregional cell proliferation. eLife, 10 e67915. doi: 10.7554/elife.67915

Collagen polarization promotes epithelial elongation by stimulating locoregional cell proliferation

2020

Journal Article

A versatile oblique plane microscope for large-scale and high-resolution imaging of subcellular dynamics

Sapoznik, Etai, Chang, Bo-Jui, Huh, Jaewon, Ju, Robert J., Azarova, Evgenia, Pohlkamp, Theresa, Welf, Erik S., Broadbent, David, Carisey, Alexandre F., Stehbens, Samantha J., Lee, Kyung-Min, Marin, Arnaldo, Hanker, Ariella B., Schmidt, Jens C., Arteaga, Carlos L., Bin Yang, , Kobayashi, Yoshihiko, Tata, Purushothama Rao, Kruithoff, Rory, Doubrovinski, Konstantin, Shepherd, Douglas P., Millett-Sikking, Alfred, York, Andrew G., Dean, Kevin M. and Fiolka, Reto P. (2020). A versatile oblique plane microscope for large-scale and high-resolution imaging of subcellular dynamics. eLife, 9 e57681, 1-39. doi: 10.7554/elife.57681

A versatile oblique plane microscope for large-scale and high-resolution imaging of subcellular dynamics

2020

Journal Article

Editorial: Forces in biology-cell and developmental mechanobiology and its implications in disease

Wu, Selwin K., Gomez, Guillermo A., Stehbens, Samantha J. and Smutny, Michael (2020). Editorial: Forces in biology-cell and developmental mechanobiology and its implications in disease. Frontiers in Cell and Developmental Biology, 8 598179, 598179. doi: 10.3389/fcell.2020.598179

Editorial: Forces in biology-cell and developmental mechanobiology and its implications in disease