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2010 Journal Article Chemical synthesis and structure of the prokineticin Bv8Morales, Rodrigo A. V., Daly, Norelle L., Vetter, Irina, Mobli, Mehdi, Napier, Ian A., Craik, David J., Lewis, Richard J., Christie, MacDonald J., King, Glenn F., Alewood, Paul F. and Durek, Thomas (2010). Chemical synthesis and structure of the prokineticin Bv8. ChemBioChem, 11 (13), 1882-1888. doi: 10.1002/cbic.201000330 |
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2009 Journal Article Chemical synthesis and folding of APETx2, a potent and selective inhibitor of acid sensing ion channel 3Jensen, J. E., Durek, T, Alewood, P. F., Adams, D. J., King, G. F. and Rash, L. D. (2009). Chemical synthesis and folding of APETx2, a potent and selective inhibitor of acid sensing ion channel 3. TOXICON, 54 (1), 56-61. doi: 10.1016/j.toxicon.2009.03.014 |
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2007 Journal Article Synthesis of photoactive analogues of a cystine knot trypsin inhibitor proteinDurek, Thomas, Zhang, Junliang, He, Chuan and Kent, Stephen B.H. (2007). Synthesis of photoactive analogues of a cystine knot trypsin inhibitor protein. Organic Letters, 9 (26), 5497-5500. doi: 10.1021/ol702461z |
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2007 Journal Article Convergent chemical synthesis and high-resolution x-ray structure of human lysozymeDurek, Thomas, Torbeev, Vladimir Yu and Kent, Stephen B. H. (2007). Convergent chemical synthesis and high-resolution x-ray structure of human lysozyme. Proceedings of the National Academy of Sciences of the United States of America, 104 (2), 4846-4851. doi: 10.1073/pnas.0610630104 |
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2006 Journal Article Total Chemical Synthesis, Folding, and Assay of a Small Protein on a Water-Compatible Solid SupportJohnson, Erik C. B., Durek, Thomas and Kent, Stephen B. H. (2006). Total Chemical Synthesis, Folding, and Assay of a Small Protein on a Water-Compatible Solid Support. Angewandte Chemie International Edition, 45 (20), 3283-3287. doi: 10.1002/anie.200600381 |
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2006 Journal Article Structure of doubly prenylated Ypt1:GDI complex and the mechanism of GDI-mediated Rab recyclingPylypenko, Olena, Rak, Alexey, Durek, Thomas, Kushnir, Susanna, Dursina, Beatrice E., Thomae, Nicolas H., Constantinescu, Alexandru T., Brunsveld, Luc, Watzke, Anja, Waldmann, Herbert, Goody, Roger S. and Alexandrov, Kirill (2006). Structure of doubly prenylated Ypt1:GDI complex and the mechanism of GDI-mediated Rab recycling. The EMBO Journal, 25 (1), 13-23. doi: 10.1038/sj.emboj.7600921 |
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2005 Journal Article Synthesis of functionalized Rab GTPases by a combination of solution- or solid-phase lipopeptide synthesis with expressed protein ligationBrunsveld, Luc, Watzke, Anja, Durek, Thomas, Alexandrov, Kirill, Goody, Roger S. and Waldmann, Herbert (2005). Synthesis of functionalized Rab GTPases by a combination of solution- or solid-phase lipopeptide synthesis with expressed protein ligation. Chemistry: A European Journal, 11 (9), 2756-2772. doi: 10.1002/chem.200401041 |
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2005 Journal Article Chemical biology of protein lipidation: Semi-synthesis and structure elucidation of prenylated RabGTPasesWatzke, Anja, Brunsveld, Luc, Durek, Thomas, Alexandrov, Kirill, Rak, Alexey, Goody, Roger S. and Waldmann, Herbert (2005). Chemical biology of protein lipidation: Semi-synthesis and structure elucidation of prenylated RabGTPases. Organic and Biomolecular Chemistry, 3 (7), 1157-1164. doi: 10.1039/b417573e |
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2005 Journal Article Protein semi-synthesis: new proteins for functional and structural studiesDurek, Thomas and Becker, Christian F. W. (2005). Protein semi-synthesis: new proteins for functional and structural studies. Biomolecular Engineering, 22 (5-6), 153-172. doi: 10.1016/j.bioeng.2005.07.004 |
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2005 Journal Article Application of protein semisynthesis for the construction of functionalized posttranslationally modified Rab GTPasesGoody, Roger S., Durek, Thomas, Waldmann, Herbert, Brunsveld, Lucas and Alexandrov, Kirill (2005). Application of protein semisynthesis for the construction of functionalized posttranslationally modified Rab GTPases. Methods in Enzymology, 403 4, 29-42. doi: 10.1016/S0076-6879(05)03004-1 |
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2005 Conference Publication Protein semi-synthesis and its application to studies of structure and function of GTPasesRak, A, Pylypenko, O, Durek, T, Watzke, A, Waldmann, H, Goody, RS and Alexandrov, K (2005). Protein semi-synthesis and its application to studies of structure and function of GTPases. 19th American Peptide Symposium, San Diego, U.S., 18-23 June 2005. Hoboken, U.S.: Wiley Interscience. |
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2004 Journal Article Synthesis of fluorescently labeled mono- and diprenylated Rab7 GTPaseDurek, Thomas, Alexandrov, Kirill, Goody, Roger S., Hildebrand, Alexandra, Heinemann, Ines and Waldmann, Herbert (2004). Synthesis of fluorescently labeled mono- and diprenylated Rab7 GTPase. Journal of American Chemical Society, 126 (50), 16368-16378. doi: 10.1021/ja046164n |
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2004 Journal Article In vitro semi-synthesis and applications of C-terminally modified Rab proteinsDurek, Thomas, Goody, Roger S. and Alexandrov, Kirill (2004). In vitro semi-synthesis and applications of C-terminally modified Rab proteins. Methods in Molecular Biology, 283, 233-244. doi: 10.1385/1-59259-813-7:233 |
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2003 Journal Article Structure of Rab GDP-dissociation inhibitor in complex with prenylated YPT1 GTPaseRak, A., Pylypenko, O., Durek, T., Watzke, A., Kushnir, S., Brunsveld, L., Waldmann, H., Goody, R. S. and Alexandrov, K. (2003). Structure of Rab GDP-dissociation inhibitor in complex with prenylated YPT1 GTPase. Science, 302 (5645), 646-650. doi: 10.1126/science.1087761 |
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2002 Journal Article Intein-Mediated Synthesis of Geranylgeranylated Rab7 Protein in VitroAlexandrov, Kirill, Heinemann, Ines, Durek, Thomas, Sidorovitch, Vadim, Goody, Roger S. and Waldmann, Herbert (2002). Intein-Mediated Synthesis of Geranylgeranylated Rab7 Protein in Vitro. Journal of the American Chemical Society, 124 (20), 5648-5649. doi: 10.1021/ja017799e |
