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2016

Journal Article

Towards a wearable near infrared spectroscopic probe for monitoring concentrations of multiple chromophores in biological tissue in vivo

Chitnis, Danial, Airantzis, Dimitrios, Highton, David, Williams, Rhys, Phong Phan, Giagka, Vasiliki, Powell, Samuel, Cooper, Robert J., Tachtsidis, Ilias, Smith, Martin, Elwell, Clare E., Hebden, Jeremy C. and Everdell, Nicholas (2016). Towards a wearable near infrared spectroscopic probe for monitoring concentrations of multiple chromophores in biological tissue in vivo. Review of Scientific Instruments, 87 (6) 065112, 065112-1-065112-9. doi: 10.1063/1.4954722

Towards a wearable near infrared spectroscopic probe for monitoring concentrations of multiple chromophores in biological tissue in vivo

2016

Journal Article

Care of elderly patients: a prospective audit of the prevalence of hypotension and the use of BIS intraoperatively in 25 hospitals in London

Wickham, Alex, Highton, David, Martin, Daniel, The Pan London Perioperative Audit and Research Network, Anwar, Sibtain, Bampoe, Sohail, Bantel, Carsten, Gooneratne, Mevan, Hopkins, Philip, Hunningher, Annie, Johnston, Carolyn, Laycock, Helen, O'Carroll, James, Odor, Peter, Philips, Sioned, Visram, Anil and Wordsworth, Harriet (2016). Care of elderly patients: a prospective audit of the prevalence of hypotension and the use of BIS intraoperatively in 25 hospitals in London. Perioperative Medicine, 5 (1) 12. doi: 10.1186/s13741-016-0036-1

Care of elderly patients: a prospective audit of the prevalence of hypotension and the use of BIS intraoperatively in 25 hospitals in London

2016

Journal Article

Hyperoxia results in increased aerobic metabolism following acute brain injury

Ghosh, Arnab , Highton, David , Kolyva, Christina , Tachtsidis, Ilias , Elwell, Clare E. and Smith, Martin (2016). Hyperoxia results in increased aerobic metabolism following acute brain injury. Journal of Cerebral Blood Flow and Metabolism, 37 (8), 2910-2920. doi: 10.1177/0271678X16679171

Hyperoxia results in increased aerobic metabolism following acute brain injury

2016

Conference Publication

A new multichannel broadband near infrared spectroscopy system to measure the spatial distribution of cytochrome-c-oxidase and tissue oxygenation

Phan, Phong, Highton, David, Tachtsidis, Ilias, Smith, Martin and Elwell, Clare (2016). A new multichannel broadband near infrared spectroscopy system to measure the spatial distribution of cytochrome-c-oxidase and tissue oxygenation. Optical Tomography and Spectroscopy, OTS 2016, Fort Lauderdale, FL, United States, 25-28 April 2016. Washington, DC, United States: OSA - The Optical Society. doi: 10.1364/OTS.2016.OM4C.3

A new multichannel broadband near infrared spectroscopy system to measure the spatial distribution of cytochrome-c-oxidase and tissue oxygenation

2016

Conference Publication

Near infrared light scattering changes following acute brain injury

Highton, David, Tachtsidis, Ilias, Tucker, Alison, Elwell, Clare and Smith, Martin (2016). Near infrared light scattering changes following acute brain injury. 42nd Annual Meeting of International Society on Oxygen Transport to Tissue, Manchester England, 28 June - 3 July 2014. New York, NY, United States: Springer New York. doi: 10.1007/978-1-4939-3023-4_17

Near infrared light scattering changes following acute brain injury

2016

Conference Publication

Validation of a hybrid microwave-optical monitor to investigate thermal provocation in the microvasculature

Al-Armaghany, Allann, Tong, Kenneth, Highton, David and Leung, Terence S. (2016). Validation of a hybrid microwave-optical monitor to investigate thermal provocation in the microvasculature. 42nd Annual Meeting of International Society on Oxygen Transport to Tissue, Manchester England, 28 June - 3 July 2014. New York, NY United States: Springer New York LLC. doi: 10.1007/978-1-4939-3023-4_55

Validation of a hybrid microwave-optical monitor to investigate thermal provocation in the microvasculature

2016

Conference Publication

Spatial distribution of changes in oxidised cytochrome C oxidase during visual stimulation using broadband near infrared spectroscopy imaging

Phan, P., Highton, D., Brigadoi, S., Tachtsidis, I., Smith, M. and Elwell, C. E. (2016). Spatial distribution of changes in oxidised cytochrome C oxidase during visual stimulation using broadband near infrared spectroscopy imaging. 43rd Annual Meeting of the International Society on Oxygen Transport to Tissue, ISOTT 2015, Wuhan, China, 11-16 July 2015. New York, NY, United States: Springer New York LLC. doi: 10.1007/978-3-319-38810-6_26

Spatial distribution of changes in oxidised cytochrome C oxidase during visual stimulation using broadband near infrared spectroscopy imaging

2015

Journal Article

Monitoring cerebral autoregulation after brain injury: multimodal assessment of cerebral slow-wave oscillations using near-infrared spectroscopy

Highton, David, Ghosh, Arnab, Tachtsidis, Ilias, Panovska-Griffiths, Jasmina, Elwell, Clare E. and Smith, Martin (2015). Monitoring cerebral autoregulation after brain injury: multimodal assessment of cerebral slow-wave oscillations using near-infrared spectroscopy. Anesthesia and Analgesia, 121 (1), 198-205. doi: 10.1213/ANE.0000000000000790

Monitoring cerebral autoregulation after brain injury: multimodal assessment of cerebral slow-wave oscillations using near-infrared spectroscopy

2015

Journal Article

BrainSignals revisited: simplifying a computational model of cerebral physiology

Caldwell, Matthew, Hapuarachchi, Tharindi, Highton, David, Elwell, Clare, Smith, Martin and Tachtsidis, Ilias (2015). BrainSignals revisited: simplifying a computational model of cerebral physiology. PLoS One, 10 (5) e0126695, e0126695. doi: 10.1371/journal.pone.0126695

BrainSignals revisited: simplifying a computational model of cerebral physiology

2014

Journal Article

Cytochrome c oxidase response to changes in cerebral oxygen delivery in the adult brain shows higher brain-specificity than haemoglobin

Kolyva, Christina, Ghosh, Arnab, Tachtsidis, Ilias, Highton, David, Cooper, Chris E., Smith, Martin and Elwell, Clare E. (2014). Cytochrome c oxidase response to changes in cerebral oxygen delivery in the adult brain shows higher brain-specificity than haemoglobin. NeuroImage, 85 (1), 234-244. doi: 10.1016/j.neuroimage.2013.05.070

Cytochrome c oxidase response to changes in cerebral oxygen delivery in the adult brain shows higher brain-specificity than haemoglobin

2014

Conference Publication

Analysis of slow wave oscillations in cerebral haemodynamics and metabolism following subarachnoid haemorrhage

Highton, David, Ghosh, Arnab, Tachtsidis, Ilias, Elwell, Clare and Smith, Martin (2014). Analysis of slow wave oscillations in cerebral haemodynamics and metabolism following subarachnoid haemorrhage. 41st Annual Meeting of ISOTT, Hanover, NH, United States, 22 - 26 June 2013. New York, NY, United States: Springer New York LLC. doi: 10.1007/978-1-4939-0620-8_26

Analysis of slow wave oscillations in cerebral haemodynamics and metabolism following subarachnoid haemorrhage

2014

Conference Publication

Effect of blood in the cerebrospinal fluid on the accuracy of cerebral oxygenation measured by near infrared spectroscopy

Robertson, J. L., Ghosh, A., Correia, T., Highton, D., Smith, M., Elwell, C. E. and Leung, T. S. (2014). Effect of blood in the cerebrospinal fluid on the accuracy of cerebral oxygenation measured by near infrared spectroscopy. 41st Annual Meeting of ISOTT, Hanover NH, United States, 22-26 June 2013. New York NY, United States: Springer New York. doi: 10.1007/978-1-4939-0620-8_31

Effect of blood in the cerebrospinal fluid on the accuracy of cerebral oxygenation measured by near infrared spectroscopy

2013

Conference Publication

Mathematical modelling of near-infrared spectroscopy signals and intracranial pressure in brain-injured patients

Highton, David, Panovska-Griffiths, Jasmina, Smith, Martin and Elwell, Clare E. (2013). Mathematical modelling of near-infrared spectroscopy signals and intracranial pressure in brain-injured patients. 40th Annual Meeting of the International Society on Oxygen Transport to Tissue, Bruges, Belgium, 19-24 August 2012. New York NY, United States: Springer. doi: 10.1007/978-1-4614-7411-1_46

Mathematical modelling of near-infrared spectroscopy signals and intracranial pressure in brain-injured patients

2013

Conference Publication

Dependence on NIRS source-detector spacing of cytochrome c oxidase response to hypoxia and hypercapnia in the adult brain

Kolyva, Christina, Ghosh, Arnab, Tachtsidis, Ilias, Highton, David, Smith, Martin and Elwell, Clare E. (2013). Dependence on NIRS source-detector spacing of cytochrome c oxidase response to hypoxia and hypercapnia in the adult brain. 40th Annual Meeting of the International Society on Oxygen Transport to Tissue (ISOTT), Bruges Belgium, 19-24 August 2012. New York NY United States: Springer. doi: 10.1007/978-1-4614-7411-1_47

Dependence on NIRS source-detector spacing of cytochrome c oxidase response to hypoxia and hypercapnia in the adult brain

2013

Conference Publication

Normobaric hyperoxia does not change optical scattering or pathlength but does increase oxidised cytochrome c oxidase concentration in patients with brain injury

Ghosh, Arnab, Tachtsidis, Ilias, Kolyva, Christina, Highton, David, Elwell, Clare and Smith, Martin (2013). Normobaric hyperoxia does not change optical scattering or pathlength but does increase oxidised cytochrome c oxidase concentration in patients with brain injury. 39th Annual Conference of the International Society on Oxygen Transport to Tissue (ISOTT), Washington DC United States, 24-27 July 2011. New York NY United States: Springer. doi: 10.1007/978-1-4614-4989-8_10

Normobaric hyperoxia does not change optical scattering or pathlength but does increase oxidised cytochrome c oxidase concentration in patients with brain injury

2013

Conference Publication

Modelling cerebrovascular reactivity: A novel near-infrared biomarker of cerebral autoregulation?

Highton, David, Panovska-Griffiths, Jasmina, Ghosh, Arnab, Tachtsidis, Ilias, Banaji, Murad, Elwell, Clare and Smith, Martin (2013). Modelling cerebrovascular reactivity: A novel near-infrared biomarker of cerebral autoregulation?. 39th Annual Conference of the International Society on Oxygen Transport to Tissue (ISOTT), Washington DC United States, Jul 24-27, 2011. New York, NY, United States: Springer. doi: 10.1007/978-1-4614-4989-8_13

Modelling cerebrovascular reactivity: A novel near-infrared biomarker of cerebral autoregulation?

2013

Journal Article

Intensive care management of subarachnoid haemorrhage

Highton, David and Smith, Martin (2013). Intensive care management of subarachnoid haemorrhage. Journal of the Intensive Care Society, 14 (1), 28-35. doi: 10.1177/175114371301400108

Intensive care management of subarachnoid haemorrhage

2013

Conference Publication

Reduction of cytochrome c oxidase during vasovagal hypoxia-ischemia in human adult brain: A case study

Ghosh, Arnab, Kolyva, Christina, Tachtsidis, Ilias, Highton, David, Elwell, Clare E. and Smith, Martin (2013). Reduction of cytochrome c oxidase during vasovagal hypoxia-ischemia in human adult brain: A case study. 40th Annual Meeting of the International Society on Oxygen Transport to Tissue (ISOTT), Bruges Belgium, 19-24 August 2012. New York NY United States: Springer New York LLC. doi: 10.1007/978-1-4614-7411-1_4

Reduction of cytochrome c oxidase during vasovagal hypoxia-ischemia in human adult brain: A case study

2012

Conference Publication

Deoxyhaemoglobin as a biomarker of cerebral autoregulation

Highton, D, Ghosh, A, Tachtsidis, I, Kolyva, C, Panovska, J, Elwell, C and Smith, M (2012). Deoxyhaemoglobin as a biomarker of cerebral autoregulation. 32nd International Symposium on Intensive Care and Emergency Medicine, Brussels, Belgium, 20-23 March 2012. Philadelphia, PA, United States : Current Science . doi: 10.1186/cc10902

Deoxyhaemoglobin as a biomarker of cerebral autoregulation

2011

Book Chapter

Neuromonitoring

Highton, David and Smith, Martin (2011). Neuromonitoring. Handbook of Clinical Anaesthesia 3E. (pp. 338-340) CRC Press.

Neuromonitoring