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2014 Journal Article Therapeutic silencing of KRAS using systemically delivered siRNAsPecot, Chad V., Wu, Sherry Y., Bellister, Seth, Filant, Justyna, Rupaimoole, Rajesha, Hisamatsu, Takeshi, Bhattacharya, Rajat, Maharaj, Anshumaan, Azam, Salma, Rodriguez-Aguayo, Cristian, Nagaraja, Archana S., Morelli, Maria Pia, Gharpure, Kshipra M., Waugh, Trent A., Gonzalez-Villasana, Vianey, Zand, Behrouz, Dalton, Heather J., Kopetz, Scott, Lopez-Berestein, Gabriel, Ellis, Lee M. and Sood, Anil K. (2014). Therapeutic silencing of KRAS using systemically delivered siRNAs. Molecular Cancer Therapeutics, 13 (12), 2876-2885. doi: 10.1158/1535-7163.MCT-14-0074 |
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2014 Journal Article Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progressionRupaimoole, Rajesha, Wu, Sherry Y., Pradeep, Sunila, Ivan, Cristina, Pecot, Chad V., Gharpure, Kshipra M., Nagaraja, Archana S., Armaiz-Pena, Guillermo N., McGuire, Michael, Zand, Behrouz, Dalton, Heather J., Filant, Justyna, Miller, Justin Bottsford, Lu, Chunhua, Sadaoui, Nouara C., Mangala, Lingegowda S., Taylor, Morgan, van den Beucken, Twan, Koch, Elizabeth, Rodriguez-Aguayo, Cristian, Huang, Li, Bar-Eli, Menashe, Wouters, Bradly G., Radovich, Milan, Ivan, Mircea, Calin, George A., Zhang, Wei, Lopez-Berestein, Gabriel and Sood, Anil K. (2014). Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression. Nature Communications, 5 (5202) 5202. doi: 10.1038/ncomms6202 |
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2014 Journal Article Hematogenous metastasis of ovarian cancer: rethinking mode of spreadPradeep, Sunila, Kim, Seung W., Wu, Sherry Y., Nishimura, Masato, Chaluvally-Raghavan, Pradeep, Miyake, Takahito, Pecot, Chad V., Kim, Sun-Jin, Choi, Hyun Jin, Bischoff, Farideh Z., Mayer, Julie Ann, Huang, Li, Nick, Alpa M., Hall, Carolyn S., Rodriguez-Aguayo, Cristian, Zand, Behrouz, Dalton, Heather J., Arumugam, Thiruvengadam, Lee, Ho Jeong, Han, Hee Dong, Cho, Min Soon, Rupaimoole, Rajesha, Mangala, Lingegowda S., Sehgal, Vasudha, Oh, Sang Cheul, Liu, Jinsong, Lee, Ju-Seog, Coleman, Robert L., Ram, Prahlad ... Sood, Anil K. (2014). Hematogenous metastasis of ovarian cancer: rethinking mode of spread. Cancer Cell, 26 (1), 77-91. doi: 10.1016/j.ccr.2014.05.002 |
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2014 Journal Article Metronomic docetaxel in PRINT nanoparticles and EZH2 silencing have synergistic antitumor effect in ovarian cancerGharpure, Kshipra M., Chu, Kevin S., Bowerman, Charles J., Miyake, Takahito, Pradeep, Sunila, Mangala, Selanere L., Han, Hee-Dong, Rupaimoole, Rajesha, Armaiz-Pena, Guillermo N., Rahhal, Tojan B., Wu, Sherry Y., Luft, J. Christopher, Napier, Mary E., Lopez-Berestein, Gabriel, DeSimone, Joseph M. and Sood, Anil K. (2014). Metronomic docetaxel in PRINT nanoparticles and EZH2 silencing have synergistic antitumor effect in ovarian cancer. Molecular Cancer Therapeutics, 13 (7), 1750-1757. doi: 10.1158/1535-7163.MCT-13-0930 |
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2014 Journal Article Notch3 pathway alterations in ovarian cancerHu, Wei, Liu, Tao, Ivan, Cristina, Sun, Yunjie, Huang, Jie, Mangala, Lingegowda S., Miyake, Takahito, Dalton, Heather J., Pradeep, Sunila, Rupaimoole, Rajesh, Previs, Rebecca A., Han, Hee Dong, Bottsford-Miller, Justin, Zand, Behrouz, Kang, Yu, Pecot, Chad V., Nick, Alpa M., Wu, Sherry Y., Lee, Ju-Seog, Sehgal, Vasudha, Ram, Prahlad, Liu, Jinsong, Tucker, Susan L., Lopez-Berestein, Gabriel, Baggerly, Keith A., Coleman, Robert L. and Sood, Anil K. (2014). Notch3 pathway alterations in ovarian cancer. Cancer Research, 74 (12), 3282-3293. doi: 10.1158/0008-5472.CAN-13-2066 |
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2014 Journal Article Molecular biomarkers of residual disease after surgical debulking of high-grade serous ovarian cancerTucker, Susan L., Gharpure, Kshipra, Herbrich, Shelley M., Unruh, Anna K., Nick, Alpa M., Crane, Erin K., Coleman, Robert L., Guenthoer, Jamie, Dalton, Heather J., Wu, Sherry Y., Rupaimoole, Rajesha, Lopez-Berestein, Gabriel, Ozpolat, Bulent, Ivan, Cristina, Hu, Wei, Baggerly, Keith A. and Sood, Anil K. (2014). Molecular biomarkers of residual disease after surgical debulking of high-grade serous ovarian cancer. Clinical Cancer Research, 20 (12), 3280-3288. doi: 10.1158/1078-0432.CCR-14-0445 |
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2014 Journal Article RNAi therapies: drugging the undruggableWu, S. Y., Lopez-Berestein, G., Calin, G. A. and Sood, A. K. (2014). RNAi therapies: drugging the undruggable. Science Translational Medicine, 6 (240), 240ps7-240ps7. doi: 10.1126/scitranslmed.3008362 |
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2014 Journal Article 2′-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activityWu, Sherry Y., Yang, Xianbin, Gharpure, Kshipra M., Hatakeyama, Hiroto, Egli, Martin, McGuire, Michael H., Nagaraja, Archana S., Miyake, Takahito M., Rupaimoole, Rajesha, Pecot, Chad V., Taylor, Morgan, Pradeep, Sunila, Sierant, Malgorzata, Rodriguez-Aguayo, Cristian, Choi, Hyun J., Previs, Rebecca A., Armaiz-Pena, Guillermo N., Huang Li, Martinez, Carlos, Hassell Tom, Ivan, Cristina, Sehgal, Vasudha, Singhania, Richa, Han, Hee-Dong, Su, Chang, Kim, Ji Hoon, Dalton, Heather J., Kovvali, Chandra, Keyomarsi, Khandan ... Sood, Anil K. (2014). 2′-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity. Nature Communications, 5 (1) 3459. doi: 10.1038/ncomms4459 |
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2014 Journal Article Autocrine effects of tumor-derived complementCho, Min Soon, Vasquez, Hernan G., Rupaimoole, Rajesha, Pradeep, Sunila, Wu, Sherry, Zand, Behrouz, Han, Hee-Dong, Rodriguez-Aguayo, Cristian, Bottsford-Miller, Justin, Huang, Jie, Miyake, Takahito, Choi, Hyun-Jin, Dalton, Heather J., Ivan, Cristina, Baggerly, Keith, Lopez-Berestein, Gabriel, Sood, Anil K. and Afshar-Kharghan, Vahid (2014). Autocrine effects of tumor-derived complement. Cell Reports, 6 (6), 1085-1095. doi: 10.1016/j.celrep.2014.02.014 |
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2014 Conference Publication Evoking potent RNAi response using novel 2 '-OMe-phosphorodithioated modified siRNAsWu, Sherry, Yang, Xianbin, Egli, Martin, Ghaupure, Kshipra, Hatakeyama, Hiroto, McGuire, Michael, Rupaimoole, Rajesha, Miyake, Takahito, Taylor, Morgan, Pradeep, Sunila, Nagaraja, Archana, Sierant, Malgorzata, Singhania, Richa, Rodriguez-Aguayo, Cristian, McMillan, Nigel, Lopez-Berestein, Gabriel, Ram, Prahlad, Nawrot, Barbara and Sood, Anil K. (2014). Evoking potent RNAi response using novel 2 '-OMe-phosphorodithioated modified siRNAs. 105th Annual Meeting of the American Association for Cancer Research (AACR), San Diego, CA United States, 05-09 April 2014. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2014-1406 |
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2013 Journal Article Therapeutic synergy between microRNA and siRNA in ovarian cancer treatmentNishimura, Masato, Jung, Eun-Jung, Shah, Maitri Y., Lu, Chunhua, Spizzo, Riccardo, Shimizu, Masayoshi, Han, Hee Dong, Ivan, Cristina, Rossi, Simona, Zhang, Xinna, Nicoloso, Milena S., Wu, Sherry Y., Almeida, Maria Ines, Bottsford-Miller, Justin, Pecot, Chad V., Zand, Behrouz, Matsuo, Koji, Shahzad, Mian M., Jennings, Nicholas B., Rodriguez-Aguayo, Cristian, Lopez-Berestein, Gabriel, Sood, Anil K. and Calin, George A. (2013). Therapeutic synergy between microRNA and siRNA in ovarian cancer treatment. Cancer Discovery, 3 (11), 1302-1315. doi: 10.1158/2159-8290.CD-13-0159 |
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2013 Journal Article Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancerKim, Hyun Seok, Mendiratta, Saurabh, Kim, Jiyeon, Pecot, Chad Victor, Larsen, Jill E., Zubovych, Iryna, Seo, Bo Yeun, Kim, Jimi, Eskiocak, Banu, Chung, Hannah, McMillan, Elizabeth, Wu, Sherry, De Brabander, Jef, Komurov, Kakajan, Toombs, Jason E., Wei, Shuguang, Peyton, Michael, Williams, Noelle, Gazdar, Adi F., Posner, Bruce A., Brekken, Rolf A., Sood, Anil K., Deberardinis, Ralph J., Roth, Michael G., Minna, John D. and White, Michael A. (2013). Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer. Cell, 155 (3), 552-566. doi: 10.1016/j.cell.2013.09.041 |
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2013 Journal Article Role of focal adhesion kinase in regulating YB-1-mediated paclitaxel resistance in ovarian cancerKang, Yu, Hu, Wei, Ivan, Cristina, Dalton, Heather J., Miyake, Takahito, Pecot, Chad V., Zand, Behrouz, Liu, Tao, Huang, Jie, Jennings, Nicholas B., Rupaimoole, Rajesha, Taylor, Morgan, Pradeep, Sunila, Wu, Sherry Y., Lu, Chunhua, Wen, Yunfei, Huang, Jianfei, Liu, Jinsong and Sood, Anil K. (2013). Role of focal adhesion kinase in regulating YB-1-mediated paclitaxel resistance in ovarian cancer. JNCI-Journal of the National Cancer Institute, 105 (19), 1485-1495. doi: 10.1093/jnci/djt210 |
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2013 Journal Article Tumour angiogenesis regulation by the miR-200 familyPecot, Chad V., Rupaimoole, Rajesha, Yang, Da, Akbani, Rehan, Ivan, Cristina, Lu, Chunhua, Wu, Sherry, Han, Hee-Dong, Shah, Maitri Y., Rodriguez-Aguayo, Cristian, Bottsford-Miller, Justin, Liu, Yuexin, Kim, Sang Bae, Unruh, Anna, Gonzalez-Villasana, Vianey, Huang, Li, Zand, Behrouz, Moreno-Smith, Myrthala, Mangala, Lingegowda S., Taylor, Morgan, Dalton, Heather J., Sehgal, Vasudha, Wen, Yunfei, Kang, Yu, Baggerly, Keith A., Lee, Ju-Seog, Ram, Prahlad T., Ravoori, Murali K., Kundra, Vikas ... Sood, Anil K. (2013). Tumour angiogenesis regulation by the miR-200 family. Nature Communications, 4 (1) 2427. doi: 10.1038/ncomms3427 |
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2013 Journal Article A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesisMasiero, Massimo, Simões, Filipa Costa, Han, Hee Dong, Snell, Cameron, Peterkin, Tessa, Bridges, Esther, Mangala, Lingegowda S., Wu, Sherry Yen-Yao, Pradeep, Sunila, Li, Demin, Han, Cheng, Dalton, Heather, Lopez-Berestein, Gabriel, Tuynman, Jurriaan B., Mortensen, Neil, Li, Ji-Liang, Patient, Roger, Sood, Anil K., Banham, Alison H., Harris, Adrian L. and Buffa, Francesca M. (2013). A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis. Cancer Cell, 24 (2), 229-241. doi: 10.1016/j.ccr.2013.06.004 |
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2013 Journal Article Efficient biodistribution and gene silencing in the lung epithelium via intravenous liposomal delivery of siRNAMcCaskill, Jana, Singhania, Richa, Burgess, Melinda, Allavena, Rachel, Wu, Sherry, Blumenthal, Antje and McMillan, Nigel A. J. (2013). Efficient biodistribution and gene silencing in the lung epithelium via intravenous liposomal delivery of siRNA. Molecular Therapy - Nucleic Acid, 2 (1) e96, e96. doi: 10.1038/mtna.2013.22 |
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2013 Journal Article The use of lipid-based nanocarriers for targeted pain therapiesHua, Susan and Wu, Sherry Y. (2013). The use of lipid-based nanocarriers for targeted pain therapies. Frontiers in Pharmacology, 4. doi: 10.3389/fphar.2013.00143 |
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2013 Book Chapter Lowering the sirna delivery barrier: Alginate scaffolds and immune stimulationMcCaskill, Jana, Wu, Sherry, Khairuddin, Norliana and McMillan, Nigel A. J. (2013). Lowering the sirna delivery barrier: Alginate scaffolds and immune stimulation. Nanotechnology for the delivery of therapeutic nucleic acids. (pp. 193-216) edited by Dan Peer. Singapore: Pan Stanford Publishing. doi: 10.4032/9789814411059 |
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2012 Journal Article New roles opined for OPCMLWu, Sherry Y. and Sood, Anil K. (2012). New roles opined for OPCML. Cancer Discovery, 2 (2), 115-116. doi: 10.1158/2159-8290.CD-11-0356 |
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2012 Journal Article siRNA-induced immunostimulation through TLR7 promotes antitumoral activity against HPV-driven tumors in vivoKhairuddin, Norliana, Gantier, Michael P., Blake, Stephen J., Wu, Sherry Y., Behlke, Mark A., Williams, Bryan R. G. and McMillan, Nigel A. J. (2012). siRNA-induced immunostimulation through TLR7 promotes antitumoral activity against HPV-driven tumors in vivo. Immunology and Cell Biology, 90 (2), 187-196. doi: 10.1038/icb.2011.19 |
