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2014

Journal Article

Metronomic docetaxel in PRINT nanoparticles and EZH2 silencing have synergistic antitumor effect in ovarian cancer

Gharpure, Kshipra M., Chu, Kevin S., Bowerman, Charles J., Miyake, Takahito, Pradeep, Sunila, Mangala, Selanere L., Han, Hee-Dong, Rupaimoole, Rajesha, Armaiz-Pena, Guillermo N., Rahhal, Tojan B., Wu, Sherry Y., Luft, J. Christopher, Napier, Mary E., Lopez-Berestein, Gabriel, DeSimone, Joseph M. and Sood, Anil K. (2014). Metronomic docetaxel in PRINT nanoparticles and EZH2 silencing have synergistic antitumor effect in ovarian cancer. Molecular Cancer Therapeutics, 13 (7), 1750-1757. doi: 10.1158/1535-7163.MCT-13-0930

Metronomic docetaxel in PRINT nanoparticles and EZH2 silencing have synergistic antitumor effect in ovarian cancer

2014

Journal Article

Notch3 pathway alterations in ovarian cancer

Hu, Wei, Liu, Tao, Ivan, Cristina, Sun, Yunjie, Huang, Jie, Mangala, Lingegowda S., Miyake, Takahito, Dalton, Heather J., Pradeep, Sunila, Rupaimoole, Rajesh, Previs, Rebecca A., Han, Hee Dong, Bottsford-Miller, Justin, Zand, Behrouz, Kang, Yu, Pecot, Chad V., Nick, Alpa M., Wu, Sherry Y., Lee, Ju-Seog, Sehgal, Vasudha, Ram, Prahlad, Liu, Jinsong, Tucker, Susan L., Lopez-Berestein, Gabriel, Baggerly, Keith A., Coleman, Robert L. and Sood, Anil K. (2014). Notch3 pathway alterations in ovarian cancer. Cancer Research, 74 (12), 3282-3293. doi: 10.1158/0008-5472.CAN-13-2066

Notch3 pathway alterations in ovarian cancer

2014

Journal Article

Molecular biomarkers of residual disease after surgical debulking of high-grade serous ovarian cancer

Tucker, Susan L., Gharpure, Kshipra, Herbrich, Shelley M., Unruh, Anna K., Nick, Alpa M., Crane, Erin K., Coleman, Robert L., Guenthoer, Jamie, Dalton, Heather J., Wu, Sherry Y., Rupaimoole, Rajesha, Lopez-Berestein, Gabriel, Ozpolat, Bulent, Ivan, Cristina, Hu, Wei, Baggerly, Keith A. and Sood, Anil K. (2014). Molecular biomarkers of residual disease after surgical debulking of high-grade serous ovarian cancer. Clinical Cancer Research, 20 (12), 3280-3288. doi: 10.1158/1078-0432.CCR-14-0445

Molecular biomarkers of residual disease after surgical debulking of high-grade serous ovarian cancer

2014

Journal Article

RNAi therapies: drugging the undruggable

Wu, S. Y., Lopez-Berestein, G., Calin, G. A. and Sood, A. K. (2014). RNAi therapies: drugging the undruggable. Science Translational Medicine, 6 (240), 240ps7-240ps7. doi: 10.1126/scitranslmed.3008362

RNAi therapies: drugging the undruggable

2014

Journal Article

2′-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity

Wu, Sherry Y., Yang, Xianbin, Gharpure, Kshipra M., Hatakeyama, Hiroto, Egli, Martin, McGuire, Michael H., Nagaraja, Archana S., Miyake, Takahito M., Rupaimoole, Rajesha, Pecot, Chad V., Taylor, Morgan, Pradeep, Sunila, Sierant, Malgorzata, Rodriguez-Aguayo, Cristian, Choi, Hyun J., Previs, Rebecca A., Armaiz-Pena, Guillermo N., Huang Li, Martinez, Carlos, Hassell Tom, Ivan, Cristina, Sehgal, Vasudha, Singhania, Richa, Han, Hee-Dong, Su, Chang, Kim, Ji Hoon, Dalton, Heather J., Kovvali, Chandra, Keyomarsi, Khandan ... Sood, Anil K. (2014). 2′-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity. Nature Communications, 5 (1) 3459. doi: 10.1038/ncomms4459

2′-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity

2014

Journal Article

Autocrine effects of tumor-derived complement

Cho, Min Soon, Vasquez, Hernan G., Rupaimoole, Rajesha, Pradeep, Sunila, Wu, Sherry, Zand, Behrouz, Han, Hee-Dong, Rodriguez-Aguayo, Cristian, Bottsford-Miller, Justin, Huang, Jie, Miyake, Takahito, Choi, Hyun-Jin, Dalton, Heather J., Ivan, Cristina, Baggerly, Keith, Lopez-Berestein, Gabriel, Sood, Anil K. and Afshar-Kharghan, Vahid (2014). Autocrine effects of tumor-derived complement. Cell Reports, 6 (6), 1085-1095. doi: 10.1016/j.celrep.2014.02.014

Autocrine effects of tumor-derived complement

2014

Conference Publication

Evoking potent RNAi response using novel 2 '-OMe-phosphorodithioated modified siRNAs

Wu, Sherry, Yang, Xianbin, Egli, Martin, Ghaupure, Kshipra, Hatakeyama, Hiroto, McGuire, Michael, Rupaimoole, Rajesha, Miyake, Takahito, Taylor, Morgan, Pradeep, Sunila, Nagaraja, Archana, Sierant, Malgorzata, Singhania, Richa, Rodriguez-Aguayo, Cristian, McMillan, Nigel, Lopez-Berestein, Gabriel, Ram, Prahlad, Nawrot, Barbara and Sood, Anil K. (2014). Evoking potent RNAi response using novel 2 '-OMe-phosphorodithioated modified siRNAs. 105th Annual Meeting of the American Association for Cancer Research (AACR), San Diego, CA United States, 05-09 April 2014. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2014-1406

Evoking potent RNAi response using novel 2 '-OMe-phosphorodithioated modified siRNAs

2013

Journal Article

Therapeutic synergy between microRNA and siRNA in ovarian cancer treatment

Nishimura, Masato, Jung, Eun-Jung, Shah, Maitri Y., Lu, Chunhua, Spizzo, Riccardo, Shimizu, Masayoshi, Han, Hee Dong, Ivan, Cristina, Rossi, Simona, Zhang, Xinna, Nicoloso, Milena S., Wu, Sherry Y., Almeida, Maria Ines, Bottsford-Miller, Justin, Pecot, Chad V., Zand, Behrouz, Matsuo, Koji, Shahzad, Mian M., Jennings, Nicholas B., Rodriguez-Aguayo, Cristian, Lopez-Berestein, Gabriel, Sood, Anil K. and Calin, George A. (2013). Therapeutic synergy between microRNA and siRNA in ovarian cancer treatment. Cancer Discovery, 3 (11), 1302-1315. doi: 10.1158/2159-8290.CD-13-0159

Therapeutic synergy between microRNA and siRNA in ovarian cancer treatment

2013

Journal Article

Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer

Kim, Hyun Seok, Mendiratta, Saurabh, Kim, Jiyeon, Pecot, Chad Victor, Larsen, Jill E., Zubovych, Iryna, Seo, Bo Yeun, Kim, Jimi, Eskiocak, Banu, Chung, Hannah, McMillan, Elizabeth, Wu, Sherry, De Brabander, Jef, Komurov, Kakajan, Toombs, Jason E., Wei, Shuguang, Peyton, Michael, Williams, Noelle, Gazdar, Adi F., Posner, Bruce A., Brekken, Rolf A., Sood, Anil K., Deberardinis, Ralph J., Roth, Michael G., Minna, John D. and White, Michael A. (2013). Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer. Cell, 155 (3), 552-566. doi: 10.1016/j.cell.2013.09.041

Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer

2013

Journal Article

Role of focal adhesion kinase in regulating YB-1-mediated paclitaxel resistance in ovarian cancer

Kang, Yu, Hu, Wei, Ivan, Cristina, Dalton, Heather J., Miyake, Takahito, Pecot, Chad V., Zand, Behrouz, Liu, Tao, Huang, Jie, Jennings, Nicholas B., Rupaimoole, Rajesha, Taylor, Morgan, Pradeep, Sunila, Wu, Sherry Y., Lu, Chunhua, Wen, Yunfei, Huang, Jianfei, Liu, Jinsong and Sood, Anil K. (2013). Role of focal adhesion kinase in regulating YB-1-mediated paclitaxel resistance in ovarian cancer. JNCI-Journal of the National Cancer Institute, 105 (19), 1485-1495. doi: 10.1093/jnci/djt210

Role of focal adhesion kinase in regulating YB-1-mediated paclitaxel resistance in ovarian cancer

2013

Journal Article

Tumour angiogenesis regulation by the miR-200 family

Pecot, Chad V., Rupaimoole, Rajesha, Yang, Da, Akbani, Rehan, Ivan, Cristina, Lu, Chunhua, Wu, Sherry, Han, Hee-Dong, Shah, Maitri Y., Rodriguez-Aguayo, Cristian, Bottsford-Miller, Justin, Liu, Yuexin, Kim, Sang Bae, Unruh, Anna, Gonzalez-Villasana, Vianey, Huang, Li, Zand, Behrouz, Moreno-Smith, Myrthala, Mangala, Lingegowda S., Taylor, Morgan, Dalton, Heather J., Sehgal, Vasudha, Wen, Yunfei, Kang, Yu, Baggerly, Keith A., Lee, Ju-Seog, Ram, Prahlad T., Ravoori, Murali K., Kundra, Vikas ... Sood, Anil K. (2013). Tumour angiogenesis regulation by the miR-200 family. Nature Communications, 4 (1) 2427. doi: 10.1038/ncomms3427

Tumour angiogenesis regulation by the miR-200 family

2013

Journal Article

A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis

Masiero, Massimo, Simões, Filipa Costa, Han, Hee Dong, Snell, Cameron, Peterkin, Tessa, Bridges, Esther, Mangala, Lingegowda S., Wu, Sherry Yen-Yao, Pradeep, Sunila, Li, Demin, Han, Cheng, Dalton, Heather, Lopez-Berestein, Gabriel, Tuynman, Jurriaan B., Mortensen, Neil, Li, Ji-Liang, Patient, Roger, Sood, Anil K., Banham, Alison H., Harris, Adrian L. and Buffa, Francesca M. (2013). A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis. Cancer Cell, 24 (2), 229-241. doi: 10.1016/j.ccr.2013.06.004

A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis

2013

Journal Article

Efficient biodistribution and gene silencing in the lung epithelium via intravenous liposomal delivery of siRNA

McCaskill, Jana, Singhania, Richa, Burgess, Melinda, Allavena, Rachel, Wu, Sherry, Blumenthal, Antje and McMillan, Nigel A. J. (2013). Efficient biodistribution and gene silencing in the lung epithelium via intravenous liposomal delivery of siRNA. Molecular Therapy - Nucleic Acid, 2 (1) e96, e96. doi: 10.1038/mtna.2013.22

Efficient biodistribution and gene silencing in the lung epithelium via intravenous liposomal delivery of siRNA

2013

Journal Article

The use of lipid-based nanocarriers for targeted pain therapies

Hua, Susan and Wu, Sherry Y. (2013). The use of lipid-based nanocarriers for targeted pain therapies. Frontiers in Pharmacology, 4. doi: 10.3389/fphar.2013.00143

The use of lipid-based nanocarriers for targeted pain therapies

2013

Book Chapter

Lowering the sirna delivery barrier: Alginate scaffolds and immune stimulation

McCaskill, Jana, Wu, Sherry, Khairuddin, Norliana and McMillan, Nigel A. J. (2013). Lowering the sirna delivery barrier: Alginate scaffolds and immune stimulation. Nanotechnology for the delivery of therapeutic nucleic acids. (pp. 193-216) edited by Dan Peer. Singapore: Pan Stanford Publishing. doi: 10.4032/9789814411059

Lowering the sirna delivery barrier: Alginate scaffolds and immune stimulation

2012

Journal Article

siRNA-induced immunostimulation through TLR7 promotes antitumoral activity against HPV-driven tumors in vivo

Khairuddin, Norliana, Gantier, Michael P., Blake, Stephen J., Wu, Sherry Y., Behlke, Mark A., Williams, Bryan R. G. and McMillan, Nigel A. J. (2012). siRNA-induced immunostimulation through TLR7 promotes antitumoral activity against HPV-driven tumors in vivo. Immunology and Cell Biology, 90 (2), 187-196. doi: 10.1038/icb.2011.19

siRNA-induced immunostimulation through TLR7 promotes antitumoral activity against HPV-driven tumors in vivo

2012

Journal Article

New roles opined for OPCML

Wu, Sherry Y. and Sood, Anil K. (2012). New roles opined for OPCML. Cancer Discovery, 2 (2), 115-116. doi: 10.1158/2159-8290.CD-11-0356

New roles opined for OPCML

2011

Journal Article

Vaginal delivery of siRNA using a novel PEGylated lipoplex-entrapped alginate scaffold system

Wu, Sherry Y., Chang, Hsin-I, Burgess, Melinda and McMillan, Nigel A. J. (2011). Vaginal delivery of siRNA using a novel PEGylated lipoplex-entrapped alginate scaffold system. Journal of Controlled Release, 155 (3), 418-426. doi: 10.1016/j.jconrel.2011.02.002

Vaginal delivery of siRNA using a novel PEGylated lipoplex-entrapped alginate scaffold system

2011

Journal Article

Systemic delivery of E6/7 siRNA using novel lipidic particles and its application with cisplatin in cervical cancer mouse models

Wu, S. Y., Singhania, A., Burgess, M., Putral, L. N., Kirkpatrick, C., Davies, N. M. and McMillan, N. A. J. (2011). Systemic delivery of E6/7 siRNA using novel lipidic particles and its application with cisplatin in cervical cancer mouse models. Gene Therapy, 18 (1), 14-22. doi: 10.1038/gt.2010.113

Systemic delivery of E6/7 siRNA using novel lipidic particles and its application with cisplatin in cervical cancer mouse models

2011

Journal Article

Effective delivery of PEGylated siRNA-containing Lipoplexes to extraperitoneal tumours following intraperitoneal administration

Singhania, Akul, Wu, Sherry Y. and McMillan, Nigel A. J. (2011). Effective delivery of PEGylated siRNA-containing Lipoplexes to extraperitoneal tumours following intraperitoneal administration. Journal of Drug Delivery, 2011, 192562.1-192562.7. doi: 10.1155/2011/192562

Effective delivery of PEGylated siRNA-containing Lipoplexes to extraperitoneal tumours following intraperitoneal administration