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2025 Journal Article Personalised selection of medication for newly diagnosed adult epilepsy: study protocol of a first-in-class, double-blind, randomised controlled trialThom, Daniel, Chang, Richard Shek-kwan, Lannin, Natasha A, Ademi, Zanfina, Ge, Zongyuan, Reutens, David, O’Brien, Terence, D’Souza, Wendyl, Perucca, Piero, Reeder, Sandra, Nikpour, Armin, Wong, Chong, Kiley, Michelle, Saw, Jacqui-Lyn, Nicolo, John-Paul, Seneviratne, Udaya, Carney, Patrick, Jones, Dean, Somerville, Ernest, Stapleton, Clare, Foster, Emma, Vadlamudi, Lata, Vaughan, David N, Lee, James, Farrar, Tania, Howard, Mark, Sparrow, Robert, Chen, Zhibin and Kwan, Patrick (2025). Personalised selection of medication for newly diagnosed adult epilepsy: study protocol of a first-in-class, double-blind, randomised controlled trial. BMJ Open, 15 (4) e086607, e086607. doi: 10.1136/bmjopen-2024-086607 |
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2024 Journal Article Diagnosing late-onset Tay-Sachs through next generation sequencing and functional enzyme testing: from genes to enzymesTupil, Ajay R., Rivlin, Warwick, Mccombe, Pamela A., Henderson, Robert D., Rodgers, Jonathan and Vadlamudi, Lata (2024). Diagnosing late-onset Tay-Sachs through next generation sequencing and functional enzyme testing: from genes to enzymes. Neurology Genetics, 10 (6) e200205, e200205. doi: 10.1212/nxg.0000000000200205 |
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2024 Journal Article Insights into neurosteroids and their role in women with epilepsyVadlamudi, Lata, Ashley, Daniel Paul and Voinescu, P. Emanuela (2024). Insights into neurosteroids and their role in women with epilepsy. Frontiers in Global Women's Health, 5 1363470, 5. doi: 10.3389/fgwh.2024.1363470 |
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2024 Journal Article Lacosamide and pregnancy: data from spontaneous and solicited reportsPerucca, Piero, Bourikas, Dimitrios, Voinescu, P. Emanuela, Vadlamudi, Lata, Chellun, Daya, Kumke, Thomas, Werhahn, Konrad J. and Schmitz, Bettina (2024). Lacosamide and pregnancy: data from spontaneous and solicited reports. Epilepsia, 65 (5), 1275-1284. doi: 10.1111/epi.17924 |
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2024 Conference Publication Pregnancy Outcomes Following Exposure to Lacosamide: Prospective Data from Spontaneous and Solicited Reports (P4-1.011)Perucca, Piero, Bourikas, Dimitrios, Voinescu, P Emanuela, Vadlamudi, Lata, Chellun, Daya, Kumke, Thomas, Werhahn, Konrad J. and Schmitz, Bettina (2024). Pregnancy Outcomes Following Exposure to Lacosamide: Prospective Data from Spontaneous and Solicited Reports (P4-1.011). 2024 American Academy of Neurology Annual Meeting, Denver, CO United States, 13-18 April 2024. Philadelphia, PA United States: Wolters Kluwer. doi: 10.1212/wnl.0000000000204900 |
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2024 Journal Article Clinically significant changes in genes and variants associated with epilepsy over time: implications for re-analysisRobertson, Alan J., Tran, Khoa A., Bennett, Carmen, Sullivan, Clair, Stark, Zornitza, Vadlamudi, Lata and Waddell, Nicola (2024). Clinically significant changes in genes and variants associated with epilepsy over time: implications for re-analysis. Scientific Reports, 14 (1) 7717, 1-12. doi: 10.1038/s41598-024-57976-1 |
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2023 Journal Article Mosaic variants detectable in blood extend the clinico-genetic spectrum of GLI3-related Hypothalamic HamartomaGreen, Timothy E., Bennett, Mark F., Immisch, Ilka, Freeman, Jeremy L., Klein, Karl Martin, Kerrigan, John F., Vadlamudi, Lata, Heinzen, Erin L., Scheffer, Ingrid E., Harvey, A. Simon, Rosenow, Felix, Hildebrand, Michael S. and Berkovic, Samuel F. (2023). Mosaic variants detectable in blood extend the clinico-genetic spectrum of GLI3-related Hypothalamic Hamartoma. Genetics in Medicine Open, 1 (1) 100810, 100810. doi: 10.1016/j.gimo.2023.100810 |
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2022 Journal Article Early cost‐utility analysis of genetically‐guided therapy for patients with drug‐resistant epilepsyGordon, Louisa G., Elliott, Thomas M., Bennett, Carmen, Hollway, Georgina, Waddell, Nicola and Vadlamudi, Lata (2022). Early cost‐utility analysis of genetically‐guided therapy for patients with drug‐resistant epilepsy. Epilepsia, 63 (12), 3111-3121. doi: 10.1111/epi.17408 |
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2022 Journal Article A multi-disciplinary team approach to genomic testing for drug-resistant epilepsy patientsVadlamudi, Lata, Bennett, Carmen Maree, Tom, Melanie, Abdulsarool, Ghusoon, Brion, Kristian, Lundie, Ben, Aung, Hnin, Lau, Chiyan, Rodgers, Jonathan, Riney, Kate and Gordon, Louisa (2022). A multi-disciplinary team approach to genomic testing for drug-resistant epilepsy patients. Journal of Clinical Medicine, 11 (14) 4238, 1-16. doi: 10.3390/jcm11144238 |
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2022 Journal Article Human induced pluripotent stem cells generated from epilepsy patients for use as in vitro models for drug screeningHunter, Zoe L., Leeson, Hannah C., Shaker, Mohammed R., Wolvetang, Ernst J. and Vadlamudi, Lata (2022). Human induced pluripotent stem cells generated from epilepsy patients for use as in vitro models for drug screening. Stem Cell Research, 60 102673, 102673. doi: 10.1016/j.scr.2022.102673 |
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2021 Journal Article Generation of induced pluripotent stem cell lines from peripheral blood mononuclear cells of three drug resistant and three drug responsive epilepsy patientsHunter, Zoe L., Leeson, Hannah C., Shaker, Mohammed R., Wolvetang, Ernst J. and Vadlamudi, Lata (2021). Generation of induced pluripotent stem cell lines from peripheral blood mononuclear cells of three drug resistant and three drug responsive epilepsy patients. Stem Cell Research, 56 102564, 102564. doi: 10.1016/j.scr.2021.102564 |
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2021 Journal Article Developing a gene panel for pharmacoresistant epilepsy: a review of epilepsy pharmacogeneticsRodriguez-Acevedo, Astrid J., Gordon, Louisa G., Waddell, Nicola, Hollway, Georgina and Vadlamudi, Lata (2021). Developing a gene panel for pharmacoresistant epilepsy: a review of epilepsy pharmacogenetics. Pharmacogenomics, 22 (4) pgs-2020-0145, 225-234. doi: 10.2217/pgs-2020-0145 |
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2019 Journal Article Deciphering the role of epigenetics in self-limited epilepsy with centrotemporal spikesMohandas, Namitha, Loke, Yuk Jing, Mackenzie, Lisa, Bennett, Carmen, Berkovic, Samuel F., Craig, Jeffrey M. and Vadlamudi, Lata (2019). Deciphering the role of epigenetics in self-limited epilepsy with centrotemporal spikes. Epilepsy Research, 156 106163, 106163. doi: 10.1016/j.eplepsyres.2019.106163 |
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2019 Journal Article Evidence for type-specific DNA methylation patterns in epilepsy: a discordant monozygotic twin approachMohandas, Namitha, Loke, Yuk Jing, Hopkins, Stephanie, Mackenzie, Lisa, Bennett, Carmen, Berkovic, Samuel F., Vadlamudi, Lata and Craig, Jeffrey M. (2019). Evidence for type-specific DNA methylation patterns in epilepsy: a discordant monozygotic twin approach. Epigenomics, 11 (8) epi-2018-0136, 951-968. doi: 10.2217/epi-2018-0136 |
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2017 Journal Article Genetic epilepsy with febrile seizures plus: refining the spectrumZhang, Yue-Hua, Burgess, Rosemary, Malone, Jodie P., Glubb, Georgie C., Helbig, Katherine L., Vadlamudi, Lata, Kivity, Sara, Afawi, Zaid, Bleasel, Andrew, Grattan-Smith, Padraic, Grinton, Bronwyn E., Bellows, Susannah T., Vears, Danya F., Damiano, John A., Goldberg-Stern, Hadassa, Korczyn, Amos D., Dibbens, Leanne M., Ruzzo, Elizabeth K., Hildebrand, Michael S., Berkovic, Samuel F. and Scheffer, Ingrid E. (2017). Genetic epilepsy with febrile seizures plus: refining the spectrum. Neurology, 89 (12), 1210-1219. doi: 10.1212/WNL.0000000000004384 |
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2014 Journal Article Genetics of epilepsy: The testimony of twins in the molecular eraVadlamudi, Lata, Milne, Roger L., Lawrence, Kate, Heron, Sarah E., Eckhaus, Jazmin, Keay, Deborah, Connellan, Mary, Torn-Broers, Yvonne, Howell, R. Anne, Mulley, John C., Scheffer, Ingrid E., Dibbens, Leanne M., Hopper, John L. and Berkovic, Samuel F. (2014). Genetics of epilepsy: The testimony of twins in the molecular era. Neurology, 83 (12), 1042-1048. doi: 10.1212/WNL.0000000000000790 |
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2014 Journal Article Mutations in mammalian target of rapamycin regulator DEPDC5 cause focal epilepsy with brain malformationsScheffer, Ingrid E., Heron, Sarah E., Regan, Brigid M., Mandelstam, Simone, Crompton, Douglas E., Hodgson, Bree L., Licchetta, Laura, Provini, Federica, Bisulli, Francesca, Vadlamudi, Lata, Gecz, Jozef, Connelly, Alan, Tinuper, Paolo, Ricos, Michael G., Berkovic, Samuel F. and Dibbens, Leanne M. (2014). Mutations in mammalian target of rapamycin regulator DEPDC5 cause focal epilepsy with brain malformations. Annals of Neurology, 75 (5), 782-787. doi: 10.1002/ana.24126 |
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2014 Conference Publication Mutations in Depdc5 Are a Major Cause of Lesional and Non-Lesional Focal EpilepsyDibbens, L. M., Scheffer, I. E., Regan, B. M., Mandelstam, S., Crompton, D. E., Hodgson, B. L., Licchetta, L., Provini, F., Bisulli, F., Vadlamudi, L., Gecz, J., Connelly, A., Tinuper, P., Ricos, M. G., Berkovic, S. F. and Heron, S. E. (2014). Mutations in Depdc5 Are a Major Cause of Lesional and Non-Lesional Focal Epilepsy. 11th European Congress on Epileptology, Stockholm, Sweden, Jun 29-Jul 03, 2014. Hoboken, NJ, United States : Wiley-Blackwell Publishing. doi: 10.1111/epi.12675 |
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2013 Journal Article Genetics of febrile seizure subtypes and syndromes: a twin studyEckhaus, Jazmin, Lawrence, Kate M., Helbig, Ingo, Bui, Minh, Vadlamudi, Lata, Hopper, John L., Scheffer, Ingrid E. and Berkovic, Samuel F. (2013). Genetics of febrile seizure subtypes and syndromes: a twin study. Epilepsy Research, 105 (1-2), 103-109. doi: 10.1016/j.eplepsyres.2013.02.011 |
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2010 Journal Article Timing of de novo mutagenesis - A twin study of sodium-channel mutationsVadlamudi, Lata, Dibbens, Leanne M., Lawrence, Kate M., Iona, Xenia, McMahon, Jacinta M., Murrell, Wayne, Mackay-Sim, Alan, Scheffer, Ingrid E. and Berkovic, Samuel F. (2010). Timing of de novo mutagenesis - A twin study of sodium-channel mutations. New England Journal of Medicine, 363 (14), 1335-1340. doi: 10.1056/NEJMoa0910752 |
