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2022 Other Outputs snrRNA-seq_muscle_datasetNgo, Shyuan, Power, Dominique, Andersen, Stacey, Taherian Fard, Atefeh, Chang, Jeryn and Steyn, Frederik (2022). snrRNA-seq_muscle_dataset. The University of Queensland. (Dataset) doi: 10.48610/0106c8e |
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2021 Journal Article Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biologyvan Rheenen, Wouter, van der Spek, Rick A. A., Bakker, Mark K., van Vugt, Joke J. F. A., Hop, Paul J., Zwamborn, Ramona A. J., de Klein, Niek, Westra, Harm-Jan, Bakker, Olivier B., Deelen, Patrick, Shireby, Gemma, Hannon, Eilis, Moisse, Matthieu, Baird, Denis, Restuadi, Restuadi, Dolzhenko, Egor, Dekker, Annelot M., Gawor, Klara, Westeneng, Henk-Jan, Tazelaar, Gijs H. P., van Eijk, Kristel R., Kooyman, Maarten, Byrne, Ross P., Doherty, Mark, Heverin, Mark, Al Khleifat, Ahmad, Iacoangeli, Alfredo, Shatunov, Aleksey, Ticozzi, Nicola ... SLAP Consortium (2021). Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology. Nature Genetics, 53 (12), 1636-1648. doi: 10.1038/s41588-021-00973-1 |
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2021 Journal Article Addition of a carboxy terminal tail to the normally tailless gonadotropin-releasing hormone receptor impairs fertility in female miceToufaily, Chirine, Fortin, Jérôme, Alonso, Carlos A. I., Lapointe, Evelyn, Zhou, Xiang, Santiago-Andres, Yorgui, Lin, Yeu-Farn, Cui, Yimming, Wang, Ying, Devost, Dominic, Roelfsema, Ferdinand, Steyn, Frederik, Hanyaloglu, Aylin C., Hébert, Terence E., Fiordelisio, Tatiana, Boerboom, Derek and Bernard, Daniel J. (2021). Addition of a carboxy terminal tail to the normally tailless gonadotropin-releasing hormone receptor impairs fertility in female mice. eLife, 10 e72937. doi: 10.7554/eLife.72937 |
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2021 Journal Article An exercise ‘sweet spot’ reverses cognitive deficits of ageing by growth hormone-induced neurogenesisBlackmore, Daniel G., Steyn, Frederik J., Carlisle, Alison, O’Keeffe, Imogen, Vien, King-Year, Zhou, Xiaoqing, Leiter, Odette, Jhaveri, Dhanisha, Vukovic, Jana, Waters, Michael J. and Bartlett, Perry F. (2021). An exercise ‘sweet spot’ reverses cognitive deficits of ageing by growth hormone-induced neurogenesis. iScience, 24 (11) 103275, 1-25. doi: 10.1016/j.isci.2021.103275 |
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2021 Journal Article Venous creatinine as a biomarker for loss of fat‐free mass and disease progression in patients with Amyotrophic Lateral SclerosisHoldom, Cory J., Janse van Mantgem, Mark R., van Eijk, Ruben P.A., Howe, Stephanie L., van den Berg, Leonard H., McCombe, Pamela A., Henderson, Robert D., Ngo, Shyuan T. and Steyn, Frederik J. (2021). Venous creatinine as a biomarker for loss of fat‐free mass and disease progression in patients with Amyotrophic Lateral Sclerosis. European Journal of Neurology, 28 (11) ene.15003, 3615-3625. doi: 10.1111/ene.15003 |
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2021 Journal Article Low plasma hyaluronan is associated with faster functional decline in patients with amyotrophic lateral sclerosisHoldom, Cory J., Ngo, Shyuan T., McCombe, Pamela A., Henderson, Robert D. and Steyn, Frederik J. (2021). Low plasma hyaluronan is associated with faster functional decline in patients with amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 23 (1-2), 1-7. doi: 10.1080/21678421.2021.1918721 |
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2021 Journal Article A road map for remote digital health technology for motor neuron diseasevan Eijk, Ruben P A, Beelen, Anita, Kruitwagen, Esther T, Murray, Deirdre, Radakovic, Ratko, Hobson, Esther, Knox, Liam, Helleman, Jochem, Burke, Tom, Rubio Pérez, Miguel Ángel, Reviers, Evy, Genge, Angela, Steyn, Frederik J, Ngo, Shyuan, Eaglesham, John, Roes, Kit C B, van den Berg, Leonard H, Hardiman, Orla and McDermott, Christopher J (2021). A road map for remote digital health technology for motor neuron disease. Journal of Medical Internet Research, 23 (9) e28766, e28766. doi: 10.2196/28766 |
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2021 Journal Article Monocyte CD14 and HLA-DR expression increases with disease duration and severity in amyotrophic lateral sclerosisMcGill, R.B., Steyn, F.J., Ngo, S.T., Thorpe, K.A., Heggie, S., Henderson, R.D., Mccombe, P.A. and Woodruff, T.M. (2021). Monocyte CD14 and HLA-DR expression increases with disease duration and severity in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 23 (5-6), 1-8. doi: 10.1080/21678421.2021.1964531 |
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2021 Journal Article 17α-estradiol modulates IGF1 and hepatic gene expression in a sex-specific mannerSidhom, Silvana, Schneider, Augusto, Fang, Yimin, McFadden, Samuel, Darcy, Justin, Sathiaseelan, Roshini, Palmer, Allyson K, Steyn, Frederik J, Grillari, Johannes, Kopchick, John J, Bartke, Andrzej, Siddiqi, Shadab, Masternak, Michal M and Stout, Michael B (2021). 17α-estradiol modulates IGF1 and hepatic gene expression in a sex-specific manner. Journals of Gerontology. Series A: Biological Sciences and Medical Sciences, 76 (5), 778-785. doi: 10.1093/gerona/glaa215 |
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2021 Journal Article Polygenic risk score analysis for amyotrophic lateral sclerosis leveraging cognitive performance, educational attainment and schizophreniaRestuadi, Restuadi, Garton, Fleur C., Benyamin, Beben, Lin, Tian, Williams, Kelly L., Vinkhuyzen, Anna, van Rheenen, Wouter, Zhu, Zhihong, Laing, Nigel G., Mather, Karen A., Sachdev, Perminder S., Ngo, Shyuan T., Steyn, Frederik J., Wallace, Leanne, Henders, Anjali K., Visscher, Peter M., Needham, Merrilee, Mathers, Susan, Nicholson, Garth, Rowe, Dominic B., Henderson, Robert D., McCombe, Pamela A., Pamphlett, Roger, Blair, Ian P., Wray, Naomi R. and McRae, Allan F. (2021). Polygenic risk score analysis for amyotrophic lateral sclerosis leveraging cognitive performance, educational attainment and schizophrenia. European Journal of Human Genetics, 30 (5), 1-8. doi: 10.1038/s41431-021-00885-y |
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2021 Journal Article Development of a highly sensitive ELISA for measurement of FSH in serum, plasma, and whole blood in miceOngaro, Luisina, Alonso, Carlos Agustin Isidro, Zhou, Xiang, Brûlé, Emilie, Li, Yining, Schang, Gauthier, Parlow, Albert F., Steyn, Frederik and Bernard, Daniel J. (2021). Development of a highly sensitive ELISA for measurement of FSH in serum, plasma, and whole blood in mice. Endocrinology, 162 (4) bqab014, 1-11. doi: 10.1210/endocr/bqab014 |
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2021 Journal Article Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disordersNabais, Marta F., Laws, Simon M., Lin, Tian, Vallerga, Costanza L., Armstrong, Nicola J., Blair, Ian P., Kwok, John B., Mather, Karen A., Mellick, George D., Sachdev, Perminder S., Wallace, Leanne, Henders, Anjali K., Zwamborn, Ramona A. J., Hop, Paul J., Lunnon, Katie, Pishva, Ehsan, Roubroeks, Janou A. Y., Soininen, Hilkka, Tsolaki, Magda, Mecocci, Patrizia, Lovestone, Simon, Kloszewska, Iwona, Vellas, Bruno, Furlong, Sarah, Garton, Fleur C., Henderson, Robert D., Mathers, Susan, McCombe, Pamela A., Needham, Merrilee ... McRae, Allan F. (2021). Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders. Genome Biology, 22 (1) 90, 1-30. doi: 10.1186/s13059-021-02275-5 |
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2021 Journal Article Ghrelin as a treatment for amyotrophic lateral sclerosisNgo, Shyuan T., Wang, Hao, Henderson, Robert D., Bowers, Cyril and Steyn, Frederik J. (2021). Ghrelin as a treatment for amyotrophic lateral sclerosis. Journal of Neuroendocrinology, 33 (7) e12938, 1-10. doi: 10.1111/jne.12938 |
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2021 Journal Article CNS glucose metabolism in amyotrophic lateral sclerosis: a therapeutic target?Tefera, Tesfaye Wolde, Steyn, Frederik J., Ngo, Shyuan T. and Borges, Karin (2021). CNS glucose metabolism in amyotrophic lateral sclerosis: a therapeutic target?. Cell & Bioscience, 11 (1) 14, 14. doi: 10.1186/s13578-020-00511-2 |
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2021 Book Chapter Hypothalamus and weight loss in amyotrophic lateral sclerosisAhmed, Rebekah M., Steyn, Frederik and Dupuis, Luc (2021). Hypothalamus and weight loss in amyotrophic lateral sclerosis. Handbook of clinical neurology. (pp. 327-338) Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-12-820107-7.00020-3 |
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2020 Journal Article Genome-wide meta-analysis finds the ACSL5-ZDHHC6 locus is associated with ALS and links weight loss to the disease geneticsIacoangeli, Alfredo, Lin, Tian, Al Khleifat, Ahmad, Jones, Ashley R., Opie-Martin, Sarah, Coleman, Jonathan R.I., Shatunov, Aleksey, Sproviero, William, Williams, Kelly L., Garton, Fleur, Restuadi, Restuadi, Henders, Anjali K., Mather, Karen A., Needham, Merilee, Mathers, Susan, Nicholson, Garth A., Rowe, Dominic B., Henderson, Robert, McCombe, Pamela A., Pamphlett, Roger, Blair, Ian P., Schultz, David, Sachdev, Perminder S., Newhouse, Stephen J., Proitsi, Petroula, Fogh, Isabella, Ngo, Shyuan T., Dobson, Richard J.B., Wray, Naomi R. ... Al-Chalabi, Ammar (2020). Genome-wide meta-analysis finds the ACSL5-ZDHHC6 locus is associated with ALS and links weight loss to the disease genetics. Cell Reports, 33 (4) 108323, 1-9. doi: 10.1016/j.celrep.2020.108323 |
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2020 Journal Article Altered skeletal muscle glucose-fatty acid flux in amyotrophic lateral sclerosisSteyn, Frederik J., Li, Rui, Kirk, Siobhan E., Tefera, Tesfaye W, Xie, Teresa Y., Tracey, Timothy J., Kelk, Dean, Wimberger, Elyse, Garton, Fleur C., Roberts, Llion, Chapman, Sarah E., Coombes, Jeff S., Leevy, W. Matthew, Ferri, Alberto, Valle, Cristiana, René, Frédérique, Loeffler, Jean-Philippe, McCombe, Pamela A., Henderson, Robert D. and Ngo, Shyuan T. (2020). Altered skeletal muscle glucose-fatty acid flux in amyotrophic lateral sclerosis. Brain Communications, 2 (2) fcaa154, fcaa154. doi: 10.1093/braincomms/fcaa154 |
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2020 Journal Article The role of lipids in the central nervous system and their pathological implications in amyotrophic lateral sclerosisTracey, T. J., Kirk, S. E., Steyn, F. J. and Ngo, S. T. (2020). The role of lipids in the central nervous system and their pathological implications in amyotrophic lateral sclerosis. Seminars in Cell and Developmental Biology, 112, 69-81. doi: 10.1016/j.semcdb.2020.08.012 |
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2020 Journal Article Prognostic value of weight loss in patients with amyotrophic lateral sclerosisSteyn, Frederik J and Ngo, Shyuan T (2020). Prognostic value of weight loss in patients with amyotrophic lateral sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 91 (8), 813-813. doi: 10.1136/jnnp-2020-323440 |
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2020 Journal Article Response to Letter to the Editor: "IGSF1 Deficiency Results in Human and Murine Somatotrope Neurosecretory Hyperfunction"Joustra, Sjoerd D., Roelfsema, Ferdinand, van Trotsenburg, A. S. Paul, Schneider, Harald J., Kosilek, Robert P., Kroon, Herman M., Logan, John G., Butterfield, Natalie C., Zhou, Xiang, Toufaily, Chirine, Bak, Beata, Turgeon, Marc-Olivier, Brule, Emilie, Steyn, Frederik J., Gurnell, Mark, Koulouri, Olympia, Le Tissier, Paul, Fontanaud, Pierre, Bassett, J. H. Duncan, Williams, Graham R., Oostdijk, Wilma, Wit, Jan M., Pereira, Alberto M., Biermasz, Nienke R., Bernard, Daniel J. and Schoenmakers, Nadia (2020). Response to Letter to the Editor: "IGSF1 Deficiency Results in Human and Murine Somatotrope Neurosecretory Hyperfunction". Journal of Clinical Endocrinology and Metabolism, 105 (6), E2315-E2316. doi: 10.1210/clinem/dgaa147 |
