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2020

Journal Article

Assessment and visualization of phenome-wide causal relationships using genetic data: an application to dental caries and periodontitis

Haworth, Simon, Kho, Pik Fang, Holgerson, Pernilla Lif, Hwang, Liang-Dar, Timpson, Nicholas J., Rentería, Miguel E., Johansson, Ingegerd and Cuellar-Partida, Gabriel (2020). Assessment and visualization of phenome-wide causal relationships using genetic data: an application to dental caries and periodontitis. European Journal of Human Genetics, 29 (2), 300-308. doi: 10.1038/s41431-020-00734-4

Assessment and visualization of phenome-wide causal relationships using genetic data: an application to dental caries and periodontitis

2020

Journal Article

Genome-wide association study identifies 48 common genetic variants associated with handedness

Cuellar-Partida, Gabriel, Tung, Joyce Y., Eriksson, Nicholas, Albrecht, Eva, Aliev, Fazil, Andreassen, Ole A., Barroso, Inês, Beckmann, Jacques S., Boks, Marco P., Boomsma, Dorret I., Boyd, Heather A., Breteler, Monique M. B., Campbell, Harry, Chasman, Daniel I., Cherkas, Lynn F., Davies, Gail, de Geus, Eco J. C., Deary, Ian J., Deloukas, Panos, Dick, Danielle M., Duffy, David L., Eriksson, Johan G., Esko, Tõnu, Feenstra, Bjarke, Geller, Frank, Gieger, Christian, Giegling, Ina, Gordon, Scott D., Han, Jiali ... Medland, Sarah E. (2020). Genome-wide association study identifies 48 common genetic variants associated with handedness. Nature Human Behaviour, 5 (1), 59-70. doi: 10.1038/s41562-020-00956-y

Genome-wide association study identifies 48 common genetic variants associated with handedness

2020

Journal Article

More than smell - COVID-19 is associated with severe impairment of smell, taste, and chemesthesis

Parma, Valentina, Ohla, Kathrin, Veldhuizen, Maria G., Niv, Masha Y., Kelly, Christine E., Bakke, Alyssa J., Cooper, Keiland W., Bouysset, Cédric, Pirastu, Nicola, Dibattista, Michele, Kaur, Rishemjit, Liuzza, Marco Tullio, Pepino, Marta Y., Schöpf, Veronika, Pereda-Loth, Veronica, Olsson, Shannon B., Gerkin, Richard C., Rohlfs Domínguez, Paloma, Albayay, Javier, Farruggia, Michael C., Bhutani, Surabhi, Fjaeldstad, Alexander W., Kumar, Ritesh, Menini, Anna, Bensafi, Moustafa, Sandell, Mari, Konstantinidis, Iordanis, Di Pizio, Antonella, Genovese, Federica ... Hayes, John E. (2020). More than smell - COVID-19 is associated with severe impairment of smell, taste, and chemesthesis. Chemical Senses, 45 (7), 609-622. doi: 10.1093/chemse/bjaa041

More than smell - COVID-19 is associated with severe impairment of smell, taste, and chemesthesis

2020

Journal Article

Educational attainment polygenic scores are associated with cortical total surface area and regions important for language and memory

Mitchell, Brittany L., Cuéllar-Partida, Gabriel, Grasby, Katrina L., Campos, Adrian I., Strike, Lachlan T., Hwang, Liang-Dar, Okbay, Aysu, Thompson, Paul M., Medland, Sarah E., Martin, Nicholas G., Wright, Margaret J. and Rentería, Miguel E. (2020). Educational attainment polygenic scores are associated with cortical total surface area and regions important for language and memory. NeuroImage, 212 116691, 116691. doi: 10.1016/j.neuroimage.2020.116691

Educational attainment polygenic scores are associated with cortical total surface area and regions important for language and memory

2020

Journal Article

Proxy gene-by-environment Mendelian randomization for assessing causal effects of maternal exposures on offspring outcomes

Hwang, Liang-Dar and Evans, David M. (2020). Proxy gene-by-environment Mendelian randomization for assessing causal effects of maternal exposures on offspring outcomes. International Journal of Epidemiology, 49 (4), 1218-1220. doi: 10.1093/ije/dyaa069

Proxy gene-by-environment Mendelian randomization for assessing causal effects of maternal exposures on offspring outcomes

2020

Journal Article

Author Correction: Understanding the role of bitter taste perception in coffee, tea and alcohol consumption through Mendelian randomization

Ong, Jue-Sheng, Hwang, Liang-Dar, Zhong, Victor W., An, Jiyuan, Gharahkhani, Puya, Breslin, Paul A. S., Wright, Margaret J., Lawlor, Deborah A., Whitfield, John, MacGregor, Stuart, Martin, Nicholas G. and Corneli, Marilyn C. (2020). Author Correction: Understanding the role of bitter taste perception in coffee, tea and alcohol consumption through Mendelian randomization. Scientific Reports, 10 (1) 4778, 4778. doi: 10.1038/s41598-020-60488-3

Author Correction: Understanding the role of bitter taste perception in coffee, tea and alcohol consumption through Mendelian randomization

2020

Journal Article

Integrating family-based and Mendelian randomization designs

Hwang, Liang-Dar, Davies, Neil M., Warrington, Nicole M. and Evans, David M. (2020). Integrating family-based and Mendelian randomization designs. Cold Spring Harbor Perspectives in Medicine, 11 (3) a039503, 1-15. doi: 10.1101/cshperspect.a039503

Integrating family-based and Mendelian randomization designs

2020

Journal Article

Do people with lower IQ have weaker taste perception? A hidden supplementary table in 'Is the Association between Sweet and Bitter Perception Due to Genetic Variation?'

Hwang, Liang-Dar (2020). Do people with lower IQ have weaker taste perception? A hidden supplementary table in 'Is the Association between Sweet and Bitter Perception Due to Genetic Variation?'. Twin Research and Human Genetics, 23 (2), 1-2. doi: 10.1017/thg.2020.19

Do people with lower IQ have weaker taste perception? A hidden supplementary table in 'Is the Association between Sweet and Bitter Perception Due to Genetic Variation?'

2019

Journal Article

Chemosensory changes from cancer treatment and their effects on patients’ food behavior: a scoping review

Nolden, Alissa A., Hwang, Liang-Dar, Boltong, Anna and Reed, Danielle R. (2019). Chemosensory changes from cancer treatment and their effects on patients’ food behavior: a scoping review. Nutrients, 11 (10) 2285, 2285. doi: 10.3390/nu11102285

Chemosensory changes from cancer treatment and their effects on patients’ food behavior: a scoping review

2019

Journal Article

Using a two-sample Mendelian randomization design to investigate a possible causal effect of maternal lipid concentrations on offspring birth weight

Hwang, Liang-Dar, Lawlor, Deborah A., Freathy, Rachel M., Evans, David M. and Warrington, Nicole M. (2019). Using a two-sample Mendelian randomization design to investigate a possible causal effect of maternal lipid concentrations on offspring birth weight. International Journal of Epidemiology, 48 (5), 1457-1467. doi: 10.1093/ije/dyz160

Using a two-sample Mendelian randomization design to investigate a possible causal effect of maternal lipid concentrations on offspring birth weight

2019

Journal Article

New insight into human sweet taste: a genome-wide association study of the perception and intake of sweet substances

Hwang, Liang-Dar, Lin, Cailu, Gharahkhani, Puya, Cuellar-Partida, Gabriel, Ong, Jue-Sheng, An, Jiyuan, Gordon, Scott D., Zhu, Gu, MacGregor, Stuart, Lawlor, Deborah A., Breslin, Paul A. S., Wright, Margaret J., Martin, Nicholas G. and Reed, Danielle R. (2019). New insight into human sweet taste: a genome-wide association study of the perception and intake of sweet substances. The American Journal of Clinical Nutrition, 109 (6), 1724-1737. doi: 10.1093/ajcn/nqz043

New insight into human sweet taste: a genome-wide association study of the perception and intake of sweet substances

2019

Journal Article

Associations between brain structure and perceived intensity of sweet and bitter tastes

Hwang, Liang-Dar, Strike, Lachlan T, Couvy-Duchesne, Baptiste, de Zubicaray, Greig I, McMahon, Katie, Breslin, Paul A. S., Reed, Danielle R., Martin, Nicholas G. and Wright, Margaret J. (2019). Associations between brain structure and perceived intensity of sweet and bitter tastes. Behavioural Brain Research, 363, 103-108. doi: 10.1016/j.bbr.2019.01.046

Associations between brain structure and perceived intensity of sweet and bitter tastes

2019

Journal Article

Elucidating the role of maternal environmental exposures on offspring health and disease using two-sample Mendelian randomization

Evans, David M., Moen, Gunn-Helen, Hwang, Liang-Dar, Lawlor, Debbie A. and Warrington, Nicole M. (2019). Elucidating the role of maternal environmental exposures on offspring health and disease using two-sample Mendelian randomization. International Journal of Epidemiology, 48 (3), 861-875. doi: 10.1093/ije/dyz019

Elucidating the role of maternal environmental exposures on offspring health and disease using two-sample Mendelian randomization

2018

Journal Article

Understanding the role of bitter taste perception in coffee, tea and alcohol consumption through Mendelian randomization

Ong, Jue-Sheng, Hwang, Liang-Dar, Zhong, Victor W., An, Jiyuan, Gharahkhani, Puya, Breslin, Paul A. S., Wright, Margaret J., Lawlor, Deborah A., Whitfield, John, MacGregor, Stuart, Martin, Nicholas G. and Cornelis, Marilyn C. (2018). Understanding the role of bitter taste perception in coffee, tea and alcohol consumption through Mendelian randomization. Scientific Reports, 8 (1) 16414, 16414. doi: 10.1038/s41598-018-34713-z

Understanding the role of bitter taste perception in coffee, tea and alcohol consumption through Mendelian randomization

2018

Journal Article

Bivariate genome-wide association analysis strengthens the role of bitter receptor clusters on chromosomes 7 and 12 in human bitter taste

Hwang, Liang-Dar, Gharahkhani, Puya, Breslin, Paul A. S., Gordon, Scott D., Zhu, Gu, Martin, Nicholas G., Reed, Danielle R. and Wright, Margaret J. (2018). Bivariate genome-wide association analysis strengthens the role of bitter receptor clusters on chromosomes 7 and 12 in human bitter taste. BMC Genomics, 19 (678) 678, 678. doi: 10.1186/s12864-018-5058-2

Bivariate genome-wide association analysis strengthens the role of bitter receptor clusters on chromosomes 7 and 12 in human bitter taste

2017

Journal Article

Assessment of moderate coffee consumption and risk of epithelial ovarian cancer: a Mendelian randomization study

Ong, Jue-Sheng, Hwang, Liang-Dar, Cuellar-Partida, Gabriel, Martin, Nicholas G., Chenevix-Trench, Georgia, Quinn, Michael C. J., Cornelis, Marilyn C., Gharahkhani, Puya, Webb, Penelope M., MacGregor, Stuart and Ovarian Cancer Association Consortium (2017). Assessment of moderate coffee consumption and risk of epithelial ovarian cancer: a Mendelian randomization study. International Journal of Epidemiology, 47 (2), 450-459. doi: 10.1093/ije/dyx236

Assessment of moderate coffee consumption and risk of epithelial ovarian cancer: a Mendelian randomization study

2017

Journal Article

Caffeine bitterness is related to daily caffeine intake and bitter receptor mRNA abundance in human taste tissue

Lipchock, Sarah V., Spielman, Andrew I., Mennella, Julie A., Mansfield, Corrine J., Hwang, Liang-Dar, Douglas, Jennifer E. and Reed, Danielle R. (2017). Caffeine bitterness is related to daily caffeine intake and bitter receptor mRNA abundance in human taste tissue. Perception, 46 (3-4), 245-256. doi: 10.1177/0301006616686098

Caffeine bitterness is related to daily caffeine intake and bitter receptor mRNA abundance in human taste tissue

2017

Journal Article

Genetic analysis of impaired trimethylamine metabolism using whole exome sequencing

Guo, Yiran, Hwang, Liang-Dar, Li, Jiankang, Eades, Jason, Yu, Chung Wen, Mansfield, Corrine, Burdick-Will, Alexis, Chang, Xiao, Chen, Yulan, Duke, Fujiko F, Zhang, Jianguo, Fakharzadeh, Steven, Fennessey, Paul, Keating, Brendan J, Jiang, Hui, Hakonarson, Hakon, Reed, Danielle R and Preti, George (2017). Genetic analysis of impaired trimethylamine metabolism using whole exome sequencing. BMC Medical Genetics, 18 (1) 11. doi: 10.1186/s12881-017-0369-8

Genetic analysis of impaired trimethylamine metabolism using whole exome sequencing

2016

Journal Article

Is the association between sweet and bitter perception due to genetic variation?

Hwang, Liang-Dar, Breslin, Paul A. S., Reed, Danielle R., Zhu, Gu, Martin, Nicholas G. and Wright, Margaret J. (2016). Is the association between sweet and bitter perception due to genetic variation?. Chemical Senses, 41 (9), 737-744. doi: 10.1093/chemse/bjw083

Is the association between sweet and bitter perception due to genetic variation?

2016

Journal Article

Sweet taste perception is associated with body mass index at the phenotypic and genotypic level

Hwang, Liang-Dar, Cuellar-Partida, Gabriel, Ong, Jue-Sheng, Breslin, Paul A. S., Reed, Danielle R., Macgregor, Stuart, Gharahkhani, Puya, Martin, Nicholas G. and Renteria, Miguel E. (2016). Sweet taste perception is associated with body mass index at the phenotypic and genotypic level. Twin Research and Human Genetics, 19 (5), 465-471. doi: 10.1017/thg.2016.60

Sweet taste perception is associated with body mass index at the phenotypic and genotypic level