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2012 Journal Article Modulating human proteinase activated receptor 2 with a novel antagonist (GB88) and agonist (GB110)Suen, J. Y., Barry, G. D., Lohman, R. J., Halili, M. A., Cotterell, A. J., Le, G. T. and Fairlie, D. P. (2012). Modulating human proteinase activated receptor 2 with a novel antagonist (GB88) and agonist (GB110). British Journal of Pharmacology, 165 (5), 1413-1423. doi: 10.1111/j.1476-5381.2011.01610.x |
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2012 Journal Article Antagonism of protease-activated receptor 2 protects against experimental colitis.Lohman, Rink-Jan, Cotterell, Adam J., Suen, Jacky, Liu, Ligong, Do, Anh T., Vesey, David A. and Fairlie, David P. (2012). Antagonism of protease-activated receptor 2 protects against experimental colitis.. Journal of Pharmacology and Experimental Therapeutics, 340 (2), 256-265. doi: 10.1124/jpet.111.187062 |
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2011 Conference Publication Towards orally bioavailable peptides and peptidomimeticsFairlie, David P., Stoermer, Martin, Lucke, Andrew, Lohman, Rink-Jan, Liu, Ligong and Ruiz-Gomez, Gloria (2011). Towards orally bioavailable peptides and peptidomimetics. 241st National Meeting and Exposition of the American-Chemical-Society (ACS), Anaheim, CA, United States, 27-31 March 2011. Washington, DC, United States: American Chemical Society. |
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2011 Conference Publication Novel agonists and antagonists for protease activated receptor 2Yau, Annika M., Liu, Ligong, Reid, Robert C., Barry, Grant D., Suen, Jacky Y., Lohman, Rink-Jan, Le, Giang T., Cotterell, Adam and Fairlie, David P. (2011). Novel agonists and antagonists for protease activated receptor 2. National Meeting of the American Chemical Society (242nd, ACS, 2011), Denver, CO, U.S.A., 28 August-1 September 2011. WASHINGTON: AMER CHEMICAL SOC. |
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2010 Journal Article Novel helix-constrained nociceptin derivatives are potent agonists and antagonists of ERK phosphorylation and thermal analgesia in miceHarrison, Rosemary S., Ruiz-Gomez, Gloria, Hill, Timothy A., Chow, Shiao Y., Shepherd, Nicholas E., Lohman, Rink-Jan, Abbenante, Giovanni, Hoang, Huy N. and Fairlie, David P. (2010). Novel helix-constrained nociceptin derivatives are potent agonists and antagonists of ERK phosphorylation and thermal analgesia in mice. Journal of Medicinal Chemistry, 53 (23), 8400-8408. doi: 10.1021/jm101139f |
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2009 Journal Article A regulatory role for protease-activated receptor-2 in motivational learning in ratsLohman, Rink-Jan, Jones, Nigel C., O’Brien, Terence J. and Cocks, Thomas M. (2009). A regulatory role for protease-activated receptor-2 in motivational learning in rats. Neurobiology of Learning and Memory, 92 (3), 301-309. doi: 10.1016/j.nlm.2009.03.010 |
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2009 Conference Publication Regulating protein and peptide activated GPCRsFairlie, David P., Madala, Praveen K., Stoermer, Martin J., Suen, Jacky, Barry, Grant and Lohman, Rink-Jan (2009). Regulating protein and peptide activated GPCRs. 229th National Meeting of the American Chemical Society, San Diego, California, 13-17 March 2005. Washington DC, United States: American Chemical Society. |
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2008 Journal Article Protease-activated receptor-2 regulates trypsin expression in the brain and protects against seizures and epileptogenesisLohman, Rink-Jan, Cocks, Thomas M. and O'Brien, Terence J. (2008). Protease-activated receptor-2 regulates trypsin expression in the brain and protects against seizures and epileptogenesis. Neurobiology of Disease, 30 (1), 84-93. doi: 10.1016/j.nbd.2007.12.010 |
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2005 Journal Article Validation of a method for localised microinjection of drugs into thalamic subregions in rats for epilepsy pharmacological studiesLohman, Rink-Jan, Liu, Lige, Morris, Margaret and O’Brien, Terence J (2005). Validation of a method for localised microinjection of drugs into thalamic subregions in rats for epilepsy pharmacological studies. Journal of Neuroscience Methods, 146 (2), 191-197. doi: 10.1016/j.jneumeth.2005.02.008 |
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2005 Conference Publication Carbamazepine aggravates absence seizures in GAERS rats by acting on the ventrobasalthalamus via a GABA-A mediated mechanismO'Brien, TJ, Liu, LG, Wallengren, L, Lohman, RJ and Morris, MJ (2005). Carbamazepine aggravates absence seizures in GAERS rats by acting on the ventrobasalthalamus via a GABA-A mediated mechanism. Joint Annual Meeting of the American-Epilepsy-Society/American-Clinical-Neurophsiology-Society, Washington Dc, Dec 02-06, 2005. OXFORD: BLACKWELL PUBLISHING. |
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2004 Conference Publication GABA receptor subunit and neuropeptide-Y expression do not differ in brains of rats with genetic absence-like epilepsy compared with nonepileptic control ratsLi, S, Wallengren, CM, Lohman, R, Morris, MJ and OBrien, TJ (2004). GABA receptor subunit and neuropeptide-Y expression do not differ in brains of rats with genetic absence-like epilepsy compared with nonepileptic control rats. Annual Meeting of the American-Epilepsy-Society, New Orlands La, Dec 03-07, 2004. MALDEN: BLACKWELL PUBLISHING INC. |
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2004 Conference Publication Specific fast oscillatory thalamocortical activity in brain slices in the gaers absence epilepsy modelMyers, DE, O'Brien, TJ, Reid, CA, Adams, BE, Lohman, RJ, Berkovic, S and Williams, DA (2004). Specific fast oscillatory thalamocortical activity in brain slices in the gaers absence epilepsy model. Annual Meeting of the American-Epilepsy-Society, New Orlands La, Dec 03-07, 2004. MALDEN: BLACKWELL PUBLISHING INC. |
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2004 Conference Publication Neuronal activation in the thalamic reticular nucleus correlates with seizure burden but not carbamazepine treatment in a rat model of absence epilepsyWallengren, CM, Morris, MJ, Li, S, Lohman, R, Jupp, B and OBrien, TJ (2004). Neuronal activation in the thalamic reticular nucleus correlates with seizure burden but not carbamazepine treatment in a rat model of absence epilepsy. Annual Meeting of the American-Epilepsy-Society, New Orlands La, Dec 03-07, 2004. MALDEN: BLACKWELL PUBLISHING INC. |
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2004 Conference Publication Chronic low-dose corticosterone supplementation enhances acquired epileptogenesis in the rat amygdala kindling model of TLETaher, T, Salzberg, M, Morris, M, Lohman, RJ, Jupp, B and O'Brien, TJ (2004). Chronic low-dose corticosterone supplementation enhances acquired epileptogenesis in the rat amygdala kindling model of TLE. Annual Meeting of the American-Epilepsy-Society, New Orlands La, Dec 03-07, 2004. MALDEN: BLACKWELL PUBLISHING INC. |
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2002 Journal Article Action potential afterdepolarization mediated by a Ca2+-activated cation conductance in myenteric AH neuronsVogal, F., Harvey, J. R., Lohman, R. -J. and Furness, J. B. (2002). Action potential afterdepolarization mediated by a Ca2+-activated cation conductance in myenteric AH neurons. Neuroscience, 115 (2), 375-393. doi: 10.1016/S0306-4522(02)00410-4 |
