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2021

Journal Article

Clinical translation of silica nanoparticles

Janjua, Taskeen Iqbal, Cao, Yuxue, Yu, Chengzhong and Popat, Amirali (2021). Clinical translation of silica nanoparticles. Nature Reviews Materials, 6 (12), 1-3. doi: 10.1038/s41578-021-00385-x

Clinical translation of silica nanoparticles

2021

Journal Article

Nanocarriers for oral delivery of biologics: small carriers for big payloads

Cao, Yuxue, Rewatkar, Prarthana, Wang, Ran, Hasnain, Sumaira Z., Popat, Amirali and Kumeria, Tushar (2021). Nanocarriers for oral delivery of biologics: small carriers for big payloads. Trends in Pharmacological Sciences, 42 (11), 957-972. doi: 10.1016/j.tips.2021.08.005

Nanocarriers for oral delivery of biologics: small carriers for big payloads

2021

Journal Article

Mesoporous silica nanoparticles improve oral delivery of antitubercular bicyclic nitroimidazoles

Ang, Chee Wei, Tan, Lendl, Qu, Zhi, West, Nicholas P., Cooper, Matthew A., Popat, Amirali and Blaskovich, Mark A.T. (2021). Mesoporous silica nanoparticles improve oral delivery of antitubercular bicyclic nitroimidazoles. ACS Biomaterials Science and Engineering, 8 (10) acsbiomaterials.1c00807, 4196-4206. doi: 10.1021/acsbiomaterials.1c00807

Mesoporous silica nanoparticles improve oral delivery of antitubercular bicyclic nitroimidazoles

2021

Other Outputs

Formulation and treatment methods

Florin, Timothy, Popat, Amirali and Jambhrunkar, Siddharth (2021). Formulation and treatment methods. US11077112B2.

Formulation and treatment methods

2021

Journal Article

Over the counter low-dose cannabidiol: a viewpoint from the ACRE Capacity Building Group

Hallinan, Christine Mary, Eden, Edward, Graham, Myfanwy, Greenwood, Lisa-Marie, Mills, Jessica, Popat, Amirali, Truong, Linda and Bonomo, Yvonne (2021). Over the counter low-dose cannabidiol: a viewpoint from the ACRE Capacity Building Group. Journal of Psychopharmacology, 36 (6) 02698811211035394, 2698811211035394-665. doi: 10.1177/02698811211035394

Over the counter low-dose cannabidiol: a viewpoint from the ACRE Capacity Building Group

2021

Journal Article

Extracellular vesicle nanoarchitectonics for novel drug delivery applications

Sharma, Shayna, Masud, Mostafa Kamal, Kaneti, Yusuf Valentino, Rewatkar, Prarthana, Koradia, Aayushi, Hossain, Md. Shahriar A., Yamauchi, Yusuke, Popat, Amirali and Salomon, Carlos (2021). Extracellular vesicle nanoarchitectonics for novel drug delivery applications. Small, 17 (42) 2102220, 1-22. doi: 10.1002/smll.202102220

Extracellular vesicle nanoarchitectonics for novel drug delivery applications

2021

Journal Article

pH – responsive colloidal carriers assembled from β-lactoglobulin and epsilon poly-l-lysine for oral drug delivery

Pujara, Naisarg, Giri, Rabina, Yau Wong, Kuan, Qu, Zhi, Rewatkar, Prarthana, Moniruzzaman, Md., Begun, Jakob, Ross, Benjamin P., McGuckin, Michael and Popat, Amirali (2021). pH – responsive colloidal carriers assembled from β-lactoglobulin and epsilon poly-l-lysine for oral drug delivery. Journal of Colloid and Interface Science, 589, 45-55. doi: 10.1016/j.jcis.2020.12.054

pH – responsive colloidal carriers assembled from β-lactoglobulin and epsilon poly-l-lysine for oral drug delivery

2021

Journal Article

Microfluidic assembly of pomegranate-like hierarchical microspheres for efflux regulation in oral drug delivery

Raza, Aun, Alavi, Seyed Ebrahim, Sime, Fekade Bruck, Han, Felicity Y., Roberts, Jason A., Popat, Amirali, Falconer, James R. and Kumeria, Tushar (2021). Microfluidic assembly of pomegranate-like hierarchical microspheres for efflux regulation in oral drug delivery. Acta Biomaterialia, 126, 277-290. doi: 10.1016/j.actbio.2021.03.042

Microfluidic assembly of pomegranate-like hierarchical microspheres for efflux regulation in oral drug delivery

2021

Journal Article

Sustained release ketamine-loaded porous silicon-PLGA microparticles prepared by an optimized supercritical CO2 process

Xu, Weizhi, Zhao, Zonglan, Falconer, James, Whittaker, Andrew K., Popat, Amirali, Smith, Maree T., Kumeria, Tushar and Han, Felicity Y. (2021). Sustained release ketamine-loaded porous silicon-PLGA microparticles prepared by an optimized supercritical CO2 process. Drug Delivery and Translational Research, 12 (3), 676-694. doi: 10.1007/s13346-021-00991-w

Sustained release ketamine-loaded porous silicon-PLGA microparticles prepared by an optimized supercritical CO2 process

2021

Journal Article

Frontiers in the treatment of glioblastoma: past, present and emerging

Janjua, Taskeen Iqbal, Rewatkar, Prarthana, Ahmed-Cox, Aria, Saeed, Iqira, Mansfeld, Friederike M., Kulshreshtha, Ritu, Kumeria, Tushar, Ziegler, David S., Kavallaris, Maria, Mazzieri, Roberta and Popat, Amirali (2021). Frontiers in the treatment of glioblastoma: past, present and emerging. Advanced Drug Delivery Reviews, 171, 108-138. doi: 10.1016/j.addr.2021.01.012

Frontiers in the treatment of glioblastoma: past, present and emerging

2021

Journal Article

PLGA encapsulated γ-cyclodextrin-meropenem inclusion complex formulation for oral delivery

Raza, Aun, Miles, Jared A., Bruck Sime, Fekade, Ross, Benjamin P., Roberts, Jason A., Popat, Amirali, Kumeria, Tushar and Falconer, James R. (2021). PLGA encapsulated γ-cyclodextrin-meropenem inclusion complex formulation for oral delivery. International Journal of Pharmaceutics, 597 120280, 120280. doi: 10.1016/j.ijpharm.2021.120280

PLGA encapsulated γ-cyclodextrin-meropenem inclusion complex formulation for oral delivery

2021

Journal Article

Supercritical carbon dioxide assisted complexation of benznidazole: γ-cyclodextrin for improved dissolution

Ndayishimiye, John, Popat, Amirali, Kumeria, Tushar, Blaskovich, Mark A.T. and Falconer, James Robert (2021). Supercritical carbon dioxide assisted complexation of benznidazole: γ-cyclodextrin for improved dissolution. International Journal of Pharmaceutics, 596 120240, 120240. doi: 10.1016/j.ijpharm.2021.120240

Supercritical carbon dioxide assisted complexation of benznidazole: γ-cyclodextrin for improved dissolution

2021

Journal Article

Protein nanoparticles for enhanced oral delivery of coenzyme-Q10: in vitro and in silico studies

Banun, Vanessa Jane, Rewatkar, Prarthana, Chaudhary, Zanib, Qu, Zhi, Janjua, Taskeen, Patil, Anuja, Wu, Yuao, Ta, Hang T., Bansal, Nidhi, Miles, Jared A., Ross, Benjamin P., Kumeria, Tushar and Popat, Amirali (2021). Protein nanoparticles for enhanced oral delivery of coenzyme-Q10: in vitro and in silico studies. ACS Biomaterials Science and Engineering, 9 (6) acsbiomaterials.0c01354, 2846-2856. doi: 10.1021/acsbiomaterials.0c01354

Protein nanoparticles for enhanced oral delivery of coenzyme-Q10: in vitro and in silico studies

2021

Journal Article

Emerging nanomedicines for the treatment of atopic dermatitis

Parekh, Khushali, Mehta, Tejal A., Dhas, Namdev, Kumar, Pavan and Popat, Amirali (2021). Emerging nanomedicines for the treatment of atopic dermatitis. AAPS PharmSciTech, 22 (2) 55, 55. doi: 10.1208/s12249-021-01920-3

Emerging nanomedicines for the treatment of atopic dermatitis

2021

Journal Article

Liquid CO2 formulated mesoporous silica nanoparticles for pH-responsive oral delivery of meropenem

Raza, Aun, Sime, Fekade Bruck, Cabot, Peter J., Roberts, Jason A., Falconer, James R., Kumeria, Tushar and Popat, Amirali (2021). Liquid CO2 formulated mesoporous silica nanoparticles for pH-responsive oral delivery of meropenem. ACS Biomaterials Science and Engineering, 7 (5) acsbiomaterials.0c01284, 1836-1853. doi: 10.1021/acsbiomaterials.0c01284

Liquid CO2 formulated mesoporous silica nanoparticles for pH-responsive oral delivery of meropenem

2021

Journal Article

Facile synthesis of lactoferrin conjugated ultra small large pore silica nanoparticles for the treatment of glioblastoma

Janjua, Taskeen Iqbal, Ahmed-Cox, Aria, Meka, Anand Kumar, Mansfeld, Friederike M., Forgham, Helen, Ignacio, Rosa Mistica C., Cao, Yuxue, McCarroll, Joshua A., Mazzieri, Roberta, Kavallaris, Maria and Popat, Amirali (2021). Facile synthesis of lactoferrin conjugated ultra small large pore silica nanoparticles for the treatment of glioblastoma. Nanoscale, 13 (40), 16909-16922. doi: 10.1039/d1nr03553c

Facile synthesis of lactoferrin conjugated ultra small large pore silica nanoparticles for the treatment of glioblastoma

2021

Journal Article

Engineering mesoporous silica nanoparticles towards oral delivery of vancomycin

Ndayishimiye, John, Cao, Yuxue, Kumeria, Tushar, Blaskovich, Mark A. T., Falconer, James Robert and Popat, Amirali (2021). Engineering mesoporous silica nanoparticles towards oral delivery of vancomycin. Journal of Materials Chemistry B, 9 (35), 7145-7166. doi: 10.1039/d1tb01430g

Engineering mesoporous silica nanoparticles towards oral delivery of vancomycin

2021

Journal Article

Rapid fabrication of homogeneously distributed hyper-branched gold nanostructured electrode based electrochemical immunosensor for detection of protein biomarkers

Bakshi, Shrishty, Mehta, Samriddhi, Kumeria, Tushar, Shiddiky, Muhammad J.A., Popat, Amirali, Choudhury, Sangeeta, Bose, Sudeep and Nayak, Ranu (2021). Rapid fabrication of homogeneously distributed hyper-branched gold nanostructured electrode based electrochemical immunosensor for detection of protein biomarkers. Sensors and Actuators, B: Chemical, 326 128803, 128803. doi: 10.1016/j.snb.2020.128803

Rapid fabrication of homogeneously distributed hyper-branched gold nanostructured electrode based electrochemical immunosensor for detection of protein biomarkers

2020

Journal Article

Oral meropenem for superbugs: challenges and opportunities

Raza, Aun, Ngieng, Shih Chen, Sime, Fekade Bruck, Cabot, Peter J., Roberts, Jason A., Popat, Amirali, Kumeria, Tushar and Falconer, James R. (2020). Oral meropenem for superbugs: challenges and opportunities. Drug Discovery Today, 26 (2), 551-560. doi: 10.1016/j.drudis.2020.11.004

Oral meropenem for superbugs: challenges and opportunities

2020

Journal Article

One‐pot synthesis of pH‐responsive eudragit‐mesoporous silica nanocomposites enable colonic delivery of glucocorticoids for the treatment of inflammatory bowel disease

Qu, Zhi, Wong, Kuan Yau, Moniruzzaman, Md., Begun, Jakob, Santos, Hélder A, Hasnain, Sumaira Z., Kumeria, Tushar, McGuckin, Michael A. and Popat, Amirali (2020). One‐pot synthesis of pH‐responsive eudragit‐mesoporous silica nanocomposites enable colonic delivery of glucocorticoids for the treatment of inflammatory bowel disease. Advanced Therapeutics, 4 (2) 2000165, 2000165. doi: 10.1002/adtp.202000165

One‐pot synthesis of pH‐responsive eudragit‐mesoporous silica nanocomposites enable colonic delivery of glucocorticoids for the treatment of inflammatory bowel disease