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2019 Journal Article Complex multilevel control of hemolysin production by uropathogenic Escherichia coliNhu, Nguyen Thi Khanh, Phan, Minh-Duy, Forde, Brian M., Murthy, Ambika M. V., Peters, Kate M., Day, Christopher J., Poole, Jessica, Kidd, Timothy J., Welch, Rodney A., Jennings, Michael P., Ulett, Glen C., Sweet, Matthew J., Beatson, Scott A. and Schembri, Mark A. (2019). Complex multilevel control of hemolysin production by uropathogenic Escherichia coli. mBio, 10 (5) e02248-19. doi: 10.1128/mbio.02248-19 |
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2019 Journal Article Uropathogenic Escherichia coli employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for disseminationStocks, Claudia J., Phan, Minh-Duy, Achard, Maud E. S., Nhu, Nguyen Thi Khanh, Condon, Nicholas D., Gawthorne, Jayde A., Lo, Alvin W., Peters, Kate M., McEwan, Alastair G., Kapetanovic, Ronan, Schembri, Mark A. and Sweet, Matthew J. (2019). Uropathogenic Escherichia coli employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination. Proceedings of the National Academy of Sciences, 116 (13), 6341-6350. doi: 10.1073/pnas.1820870116 |
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2019 Journal Article Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonizationMurthy, Ambika M. V., Sullivan, Matthew J., Nhu, Nguyen Thi Khanh, Lo, Alvin W., Phan, Minh-Duy, Peters, Kate M., Boucher, Dave, Schroder, Kate, Beatson, Scott A., Ulett, Glen C., Schembri, Mark A. and Sweet, Matthew J. (2019). Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonization. FASEB Journal : official publication of the Federation of American Societies for Experimental Biology, 33 (6), fj201802100R-7450. doi: 10.1096/fj.201802100R |
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2019 Journal Article Clinical and laboratory-induced colistin-resistance mechanisms in Acinetobacter baumanniiBoinett, Christine J., Cain, Amy K., Hawkey, Jane, Nhu Tran Do Hoang,, Nhu, Nguyen Thi Khanh Nhu, Pham, Thanh Duy, Dordel, Janina, Campbell, James, Nguyen Phu Huong Lan,, Mayho, Matthew, Langridge, Gemma C., Hadfield, James, Nguyen Van Vinh Chau,, Thwaites, Guy E., Parkhill, Julian, Thomson, Nicholas R., Holt, Kathryn E. and Baker, Stephen (2019). Clinical and laboratory-induced colistin-resistance mechanisms in Acinetobacter baumannii. Microbial Genomics, 5 (2) 000246. doi: 10.1099/mgen.0.000246 |
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2018 Journal Article Discovery of new genes involved in curli production by a uropathogenic Escherichia coli strain from the highly virulent O45:K1:H7 lineageNhu, Nguyen Thi Khanh, Phan, Minh-Duy, Peters, Kate M., Lo, Alvin W., Forde, Brian M., Min Chong, Teik, Yin, Wai-Fong, Chan, Kok-Gan, Chromek, Milan, Brauner, Annelie, Chapman, Matthew R., Beatson, Scott A. and Schembri, Mark A. (2018). Discovery of new genes involved in curli production by a uropathogenic Escherichia coli strain from the highly virulent O45:K1:H7 lineage. mBio, 9 (4) e01462-18. doi: 10.1128/mbio.01462-18 |
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2018 Journal Article Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophagesMurthy, Ambika M. V., Phan, Minh-Duy, Peters, Kate M., Nhu, Nguyen Thi Khanh, Welch, Rodney A., Ulett, Glen C., Schembri, Mark A. and Sweet, Matthew J. (2018). Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages. Virulence, 9 (1), 1-32. doi: 10.1080/21505594.2018.1465786 |
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2017 Journal Article Modifications in the pmrB gene are the primary mechanism for the development of chromosomally encoded resistance to polymyxins in uropathogenic Escherichia coliPhan, Minh-Duy, Nhu, Nguyen Thi Khanh, Achard, Maud E. S., Forde, Brian M., Hong, Kar Wai, Chong, Teik Min, Yin, Wai-Fong, Chan, Kok-Gan, West, Nicholas P., Walker, Mark J., Paterson, David L., Beatson, Scott A. and Schembri, Mark A. (2017). Modifications in the pmrB gene are the primary mechanism for the development of chromosomally encoded resistance to polymyxins in uropathogenic Escherichia coli. Journal of Antimicrobial Chemotherapy, 72 (10), 2729-2736. doi: 10.1093/jac/dkx204 |
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2016 Journal Article Fluorescence-based flow sorting in parallel with transposon insertion site sequencing identifies multidrug efflux systems in Acinetobacter baumanniiHassan, Karl A., Cain, Amy K., Huang, TaoTao, Liu, Qi, Elbourne, Liam D. H., Boinett, Christine J., Brzoska, Anthony J., Li, Liping, Ostrowski, Martin, Nhu, Nguyen Thi Khanh, Nhu, Tran Do Hoang, Baker, Stephen, Parkhill, Julian and Paulsen, Ian T. (2016). Fluorescence-based flow sorting in parallel with transposon insertion site sequencing identifies multidrug efflux systems in Acinetobacter baumannii. mBio, 7 (5) e01200-16. doi: 10.1128/mBio.01200-16 |
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2016 Journal Article Erratum for Ben Zakour et al., Sequential Acquisition of Virulence and Fluoroquinolone Resistance Has Shaped the Evolution of Escherichia coli ST131Ben Zakour, Nouri L, Alsheikh-Hussain, Areej S, Ashcroft, Melinda M, Khanh Nhu, Nguyen Thi, Roberts, Leah W, Stanton-Cook, Mitchell, Schembri, Mark A and Beatson, Scott A (2016). Erratum for Ben Zakour et al., Sequential Acquisition of Virulence and Fluoroquinolone Resistance Has Shaped the Evolution of Escherichia coli ST131. mBio, 7 (3), 1-1. doi: 10.1128/mBio.00958-16 |
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2016 Journal Article The induction and identification of novel Colistin resistance mutations in Acinetobacter baumannii and their implicationsNhu, Nguyen Thi Khanh, Riordan, David W., Nhu, Tran Do Hoang, Thanh, Duy Pham, Thwaites, Guy, Lan, Nguyen Phu Huong, Wren, Brendan W., Baker, Stephen and Stabler, Richard A. (2016). The induction and identification of novel Colistin resistance mutations in Acinetobacter baumannii and their implications. Scientific Reports, 6 (1) 28291, 28291. doi: 10.1038/srep28291 |
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2016 Journal Article Sequential acquisition of virulence and fluoroquinolone resistance has shaped the evolution of Escherichia coli ST131Ben Zakour, Nouri L., Alsheikh-Hussain, Areej S., Ashcroft, Melinda M., Nhu, Nguyen Thi Khanh, Roberts, Leah W., Stanton-Cook, Mitchell, Schembri, Mark A. and Beatson, Scott A. (2016). Sequential acquisition of virulence and fluoroquinolone resistance has shaped the evolution of Escherichia coli ST131. MBio, 7 (2) e00347-16, e00347-16.1-e00347-16.11. doi: 10.1128/mBio.00347-16 |
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2016 Journal Article Repeated local emergence of carbapenem-resistant Acinetobacter baumannii in a single hospital wardSchultz, Mark B., Duy, Pham Thanh, Nhu, Tran Do Hoan, Wick, Ryan R., Ingle, Danielle J., Hawkey, Jane, Edwards, David J., Kenyon, Johanna J., Nguyen Phu Huong Lan,, Campbell, James I., Thwaites, Guy, Nguyen, Thi Khanh Nhu, Hall, Ruth M., Fournier-Level, Alexandre, Baker, Stephen and Holt, Kathryn E. (2016). Repeated local emergence of carbapenem-resistant Acinetobacter baumannii in a single hospital ward. Microbial Genomics, 2 (3) 50, 1-15. doi: 10.1099/mgen.0.000050 |
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2015 Journal Article In vitro activity of colistin in antimicrobial combination against carbapenem-resistant acinetobacter baumannii isolated from patients with ventilator-associated pneumonia in VietnamLe Minh, Vien, Nhu, Nguyen Thi Khanh, Phat, Voong Vinh, Thompson, Corinne, Lan, Nguyen Phu Huong, Nga, Tran Vu Thieu, Tam, Pham Thi Thanh, Tuyen, Ha Thanh, Nhu, Tran Do Hoang, Van Hao, Nguyen, Loan, Huynh Thi, Yen, Lam Minh, Parry, Christopher M., Nghia, Ho Dang Trung, Campbell, James I., Hien, Tran Tinh, Thwaites, Louise, Thwaites, Guy, Van Vinh Chau, Nguyen and Baker, Stephen (2015). In vitro activity of colistin in antimicrobial combination against carbapenem-resistant acinetobacter baumannii isolated from patients with ventilator-associated pneumonia in Vietnam. Journal of Medical Microbiology, 64 (10), 1162-1169. doi: 10.1099/jmm.0.000137 |
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2015 Journal Article Genetic characterization of three qnrS1-harbouring multidrug-resistance plasmids and qnrS1-containing transposons circulating in Ho Chi Minh City, VietnamLe, Vien., Nhu, Nguyen Thi Khanh., Cerdeno-Tarraga, Ana., Campbell, James I., Tuyen, Ha Thanh., Nhu, Tran Do Hoang., Tam, Pham Thi Thanh., Schultsz, Constance., Thwaites, Guy., Thomson, Nicholas R. and Baker, Stephen (2015). Genetic characterization of three qnrS1-harbouring multidrug-resistance plasmids and qnrS1-containing transposons circulating in Ho Chi Minh City, Vietnam. Journal of Medical Microbiology, 64 (8) 000100, 869-878. doi: 10.1099/jmm.0.000100 |
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2015 Journal Article Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public healthHolt, Kathryn E., Wertheim, Heiman, Zadoks, Ruth N., Baker, Stephen, Whitehouse, Chris A., Dance, David, Jenney, Adam, Connor, Thomas R., Hsu, Li Yang, Severin, Juliette, Brisse, Sylvain, Cao, Hanwei, Wilksch, Jonathan, Gorrie, Claire, Schultz, Mark B., Edwards, David J., Van Nguyen, Kinh, Nguyen, Trung Vu, Dao, Trinh Tuyet, Mensink, Martijn, Le Minh, Vien, Nhu, Nguyen Thi Khanh, Schultsz, Constance, Kuntaman K., Newton P.N., Moore C.E., Strugnell R.A. and Thomson N.R. (2015). Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health. Proceedings of the National Academy of Sciences of the United States of America, 112 (27), E3574-E3581. doi: 10.1073/pnas.1501049112 |
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2015 Journal Article Molecular analysis of asymptomatic bacteriuria Escherichia coli strain VR50 reveals adaptation to the urinary tract by gene acquisitionBeatson, Scott A., Ben Zakour, Nouri L., Totsika, Makrina, Forde, Brian M., Watts, Rebecca E., Mabbett, Amanda N., Szubert, Jan M., Sarkar, Sohinee, Phan, Minh-Duy, Peters, Kate M., Petty, Nicola K., Alikhan, Nabil-Fareed, Sullivan, Mitchell J., Gawthorne, Jayde A., Stanton-Cook, Mitchell, Nguyen Thi Khanh Nhu, Chong, Teik Min, Yin, Wai-Fong, Chan, Kok-Gan, Hancock, Viktoria, Ussery, David W., Ulett, Glen C. and Schembri, Mark A. (2015). Molecular analysis of asymptomatic bacteriuria Escherichia coli strain VR50 reveals adaptation to the urinary tract by gene acquisition. Infection and Immunity, 83 (5), 1749-1764. doi: 10.1128/IAI.02810-14 |
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2014 Journal Article Emergence of carbapenem-resistant Acinetobacter baumanniias the major cause of ventilatorassociated pneumonia in intensive care unit patients at an infectious disease hospital in southern VietnamNhu, Nguyen Thi Khanh, Lan, Nguyen Phu Huong, Campbell, James I., Parry, Christopher M., Thompson, Corinne, Tuyen, Ha Thanh, Hoang, Nguyen Van Minh, Tam, Pham Thi Thanh, Le, Vien Minh, Nga, Tran Vu Thieu, Nhu, Tran Do Hoang, Van Minh, Pham, Nga, Nguyen Thi Thu, Thuy, Cao Thu, Dung, Le Thi, Yen, Nguyen Thi Thu, Hao, Nguyen Van, Loan, Huynh Thi, Nghia, Ho Dang Trung, Hien, Tran Tinh, Thwaites, Louise, Thwaites, Guy, Chau, Nguyen Van Vinh and Baker, Stephen (2014). Emergence of carbapenem-resistant Acinetobacter baumanniias the major cause of ventilatorassociated pneumonia in intensive care unit patients at an infectious disease hospital in southern Vietnam. Journal of Medical Microbiology, 63 (Pt 10), 1386-1394. doi: 10.1099/jmm.0.076646-0 |
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2011 Journal Article A multi-center randomized trial to assess the efficacy of gatifloxacin versus ciprofloxacin for the treatment of shigellosis in Vietnamese childrenVinh, Ha, Anh, Vo Thi Cuc, Anh, Nguyen Duc, Campbell, James I., Hoang, Nguyen Van Minh, Nga, Tran Vu Thieu, Nhu, Nguyen Thi Khanh, Minh, Pham Van, Thuy, Cao Thu, Duy, Pham Thanh, Phuong, Le Thi, Loan, Ha Thi, Chinh, Mai Thu, Thao, Nguyen Thi Thu, Tham, Nguyen Thi Hong, Mong, Bui Li, Bay, Phan Van Be, Day, Jeremy N., Dolecek, Christiane, Lan, Nguyen Phu Huong, Diep, To Song, Farrar, Jeremy J., Chau, Nguyen Van Vinh, Wolbers, Marcel and Baker, Stephen (2011). A multi-center randomized trial to assess the efficacy of gatifloxacin versus ciprofloxacin for the treatment of shigellosis in Vietnamese children. Plos Neglected Tropical Diseases, 5 (8) e1264, e1264. doi: 10.1371/journal.pntd.0001264 |
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2009 Journal Article A changing picture of shigellosis in southern Vietnam: shifting species dominance, antimicrobial susceptibility and clinical presentationHa Vinh, , Nguyen Thi Khanh Nhu, , Tran Vu Thieu Nga, , Pham Thanh Duy, , Campbell, James I., Nguyen Van Minh Hoang, , Maciej F Boni, , Phan Vu Tra My, , Parry, Christopher, Tran Thi Thu Nga, , Pham Van Minh, , Cao Thu Thuy, , To Song Diep, , Le Thi Phuong, , Mai Thu Chinh, , Ha Thi Loan, , Nguyen Thi Hong Tham, , Mai Ngoc Lanh, , Bui Li Mong, , Vo Thi Cuc Anh, , Phan Van Be Bay, , Nguyen Van Vinh Chau, , Farrar, Jeremy and Baker, Stephen (2009). A changing picture of shigellosis in southern Vietnam: shifting species dominance, antimicrobial susceptibility and clinical presentation. BMC Infectious Diseases, 9 (1) 204. doi: 10.1186/1471-2334-9-204 |
