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2026

Journal Article

Molecular characterisation of the Bacillus subtilis SpbK antiphage defence system

Mishra, Biswa P., Loyo, Christian L., Cai, Yanyao, Litfin, Thomas, Miraj, Gause, Brillault, Lou, Masic, Veronika, Mosaiab, Tamim, Rajaratnam, Premraj, Rudrawar, Santosh, Gu, Weixi, Kobe, Bostjan, Gerdt, Joseph P., Grossman, Alan D., Shi, Yun and Ve, Thomas (2026). Molecular characterisation of the Bacillus subtilis SpbK antiphage defence system. Nature Communications, 17 (1) 1051, 1-16. doi: 10.1038/s41467-025-67810-5

Molecular characterisation of the Bacillus subtilis SpbK antiphage defence system

2022

Journal Article

Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules

Shi, Yun, Kerry, Philip S., Nanson, Jeffrey D., Bosanac, Todd, Sasaki, Yo, Krauss, Raul, Saikot, Forhad K., Adams, Sarah E., Mosaiab, Tamim, Masic, Veronika, Mao, Xianrong, Rose, Faith, Vasquez, Eduardo, Furrer, Marieke, Cunnea, Katie, Brearley, Andrew, Gu, Weixi, Luo, Zhenyao, Brillault, Lou, Landsberg, Michael J., DiAntonio, Aaron, Kobe, Bostjan, Milbrandt, Jeffrey, Hughes, Robert O. and Ve, Thomas (2022). Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules. Molecular Cell, 82 (9), 1643-1659.e10. doi: 10.1016/j.molcel.2022.03.007

Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules

2021

Journal Article

A broadly protective antibody that targets the flavivirus NS1 protein

Modhiran, Naphak, Song, Hao, Liu, Lidong, Bletchly, Cheryl, Brillault, Lou, Amarilla, Alberto A., Xu, Xiaoying, Qi, Jianxun, Chai, Yan, Cheung, Stacey T. M., Traves, Renee, Setoh, Yin Xiang, Bibby, Summa, Scott, Connor A. P., Freney, Morgan E., Newton, Natalee D., Khromykh, Alexander A., Chappell, Keith J., Muller, David A., Stacey, Katryn J., Landsberg, Michael J., Shi, Yi, Gao, George F., Young, Paul R. and Watterson, Daniel (2021). A broadly protective antibody that targets the flavivirus NS1 protein. Science, 371 (6525), 190-194. doi: 10.1126/science.abb9425

A broadly protective antibody that targets the flavivirus NS1 protein

2020

Journal Article

The nucleosome remodeling and deacetylase complex has an asymmetric, dynamic, and modular architecture

Low, Jason K. K., Silva, Ana P. G., Sharifi Tabar, Mehdi, Torrado, Mario, Webb, Sarah R., Parker, Benjamin L., Sana, Maryam, Smits, Callum, Schmidberger, Jason W., Brillault, Lou, Jackman, Matthew J., Williams, David C., Blobel, Gerd A., Hake, Sandra B., Shepherd, Nicholas E., Landsberg, Michael J. and Mackay, Joel P. (2020). The nucleosome remodeling and deacetylase complex has an asymmetric, dynamic, and modular architecture. Cell Reports, 33 (9) 108450, 108450. doi: 10.1016/j.celrep.2020.108450

The nucleosome remodeling and deacetylase complex has an asymmetric, dynamic, and modular architecture

2020

Journal Article

Structures of fungal and plant acetohydroxyacid synthases

Lonhienne, Thierry, Low, Yu Shang, Garcia, Mario D., Croll, Tristan, Gao, Yan, Wang, Quan, Brillault, Lou, Williams, Craig M., Fraser, James A., McGeary, Ross P., West, Nicholas P., Landsberg, Michael J., Rao, Zihe, Schenk, Gerhard and Guddat, Luke W. (2020). Structures of fungal and plant acetohydroxyacid synthases. Nature, 586 (7828), 317-321+. doi: 10.1038/s41586-020-2514-3

Structures of fungal and plant acetohydroxyacid synthases

2019

Journal Article

Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin

Piper, Sarah J., Brillault, Lou, Rothnagel, Rosalba, Croll, Tristan I., Box, Joseph K., Chassagnon, Irene, Scherer, Sebastian, Goldie, Kenneth N, Jones, Sandra A, Schepers, Femke, Hartley-Tassell, Lauren, Ve, Thomas, Busby, Jason N, Dalziel, Julie E, Lott, J Shaun, Hankamer, Ben, Stahlberg, Henning, Hurst, Mark R H and Landsberg, Michael J (2019). Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin. Nature Communications, 10 (1) 1952, 1952. doi: 10.1038/s41467-019-09890-8

Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin

2017

Journal Article

Engineering recombinant virus-like nanoparticles from plants for cellular delivery

Brillault, Lou, Jutras, Philippe V., Dashti, Noor , Thuenemann, Eva C., Morgan, Garry, Lomonossoff, George P., Landsberg, Michael J. and Sainsbury, Frank (2017). Engineering recombinant virus-like nanoparticles from plants for cellular delivery. ACS Nano, 11 (4), 3476-3484. doi: 10.1021/acsnano.6b07747

Engineering recombinant virus-like nanoparticles from plants for cellular delivery

2016

Journal Article

The MTA1 subunit of the nucleosome remodeling and deacetylase complex can recruit two copies of RBBP4/7

Schmidberger, Jason W., Sharifi Tabar, Mehdi, Torrado, Mario, Silva, Ana P. G., Landsberg, Michael J., Brillault, Lou, AlQarni, Saad, Zeng, Yi Cheng, Parker, Benjamin L., Low, Jason K. K. and Mackay, Joel P. (2016). The MTA1 subunit of the nucleosome remodeling and deacetylase complex can recruit two copies of RBBP4/7. Protein Science, 25 (8), 1472-1482. doi: 10.1002/pro.2943

The MTA1 subunit of the nucleosome remodeling and deacetylase complex can recruit two copies of RBBP4/7