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2026

Journal Article

Early-stage multi-cancer detection through a plasma extracellular vesicle protein signature

Lobb, Richard J., Zhou, Quan, Fielding, David, Visan, Kekoolani S., Wuethrich, Alain, Wang, Jing, Hu, Youran, Norris, Emma L., Hastie, Marcus L., Everitt, Sarah, Parris, Brielle, Aoude, Lauren G., Bonazzi, Vanessa F., Nixon, Elizabeth, Mooi, Jennifer, Koo, Kevin M., O'Byrne, Kenneth, Kulasinghe, Arutha, Bowman, Rayleen V., Yang, Ian A., Corcoran, Niall M., Hovens, Christopher M., MacManus, Michael, Gorman, Jeffrey J., Day, Bryan W., Hartel, Gunter, Whiteman, David C., Tebbutt, Niall, Mariadason, John M. ... Möller, Andreas (2026). Early-stage multi-cancer detection through a plasma extracellular vesicle protein signature. Cell Reports Medicine, 7 (4) 102694, 1-20. doi: 10.1016/j.xcrm.2026.102694

Early-stage multi-cancer detection through a plasma extracellular vesicle protein signature

2026

Journal Article

Rapid Decentralized Prostate Cancer Risk Stratification by Portable Liquid Biopsy Analysis within a Clinical Biosensor Validation Framework

Koo, Kevin M., Phillips, Grant, Srihari, Sriganesh, Farrell, Áine, Jaradi, Binny, Fitzpatrick, Kira J., Yaxley, John W., Samaratunga, Hemamali, Mainwaring, Paul N., Ru, Ke‐lin, Korbie, Darren J., Tomlins, Scott A., Roberts, Matthew J., Gardiner, Robert A. and Trau, Matt (2026). Rapid Decentralized Prostate Cancer Risk Stratification by Portable Liquid Biopsy Analysis within a Clinical Biosensor Validation Framework. Advanced Science, 13 (13) e12126, e12126. doi: 10.1002/advs.202512126

Rapid Decentralized Prostate Cancer Risk Stratification by Portable Liquid Biopsy Analysis within a Clinical Biosensor Validation Framework

2026

Journal Article

Challenges in the development and implementation of point-of-care handheld qPCR devices

Shrestha, Kiran, Farhana, Fatema Zerin, Koo, Kevin M., Darwish, Nadim, Ross, Allen G. and Shiddiky, Muhammad J. A. (2026). Challenges in the development and implementation of point-of-care handheld qPCR devices. Small, 22 (3) e06233, 1-21. doi: 10.1002/smll.202506233

Challenges in the development and implementation of point-of-care handheld qPCR devices

2026

Journal Article

On-site amplification-free electrochemical detection of the plant pathogen Xylella fastidiosa via cathodic potential-induced DNA adsorption

Haque, Farjana, Shrestha, Kiran, Farhana, Fatema Zerin, Chakraborty, Moutoshi, Shaon, Md Akeruzzaman, Tantu, Milkiyas Toru, Bin Manjur, Omar Hamza, Aktar, Sharmin, Koo, Kevin M., Hussain, Tanveer, Gurr, Geoff M. and Shiddiky, Muhammad J. A. (2026). On-site amplification-free electrochemical detection of the plant pathogen Xylella fastidiosa via cathodic potential-induced DNA adsorption. Analyst . doi: 10.1039/d6an00096g

On-site amplification-free electrochemical detection of the plant pathogen Xylella fastidiosa via cathodic potential-induced DNA adsorption

2025

Journal Article

Preeclampsia diagnostics and therapeutics: advances, challenges, and prospects in nanoscale exosome-based clinical translation

Shaon, Md. Akeruzzaman, Farhana, Fatema Zerin, Sikder, Rushafi, Shrestha, Kiran, Haque, Farjana, Tantu, Milkiyas Toru, Bin Manjur, Omar Hamza, Aktar, Sharmin, Koo, Kevin M., Ross, Allen G. and Shiddiky, Muhammad J. A. (2025). Preeclampsia diagnostics and therapeutics: advances, challenges, and prospects in nanoscale exosome-based clinical translation. ACS Nano Medicine, 1 (2) acsnanomed.5c00056, 342-381. doi: 10.1021/acsnanomed.5c00056

Preeclampsia diagnostics and therapeutics: advances, challenges, and prospects in nanoscale exosome-based clinical translation

2025

Conference Publication

DEVELOPING A DECENTRALIZED LIQUID BIOPSY MOLECULAR DEVICE WITHIN A BIOSENSOR TECHNOLOGY CLINICAL VALIDATION FRAMEWORK

Koo, Kevin (2025). DEVELOPING A DECENTRALIZED LIQUID BIOPSY MOLECULAR DEVICE WITHIN A BIOSENSOR TECHNOLOGY CLINICAL VALIDATION FRAMEWORK. San Diego: Chemical and Biological Microsystems Society. doi: 10.70477/xkwc4140

DEVELOPING A DECENTRALIZED LIQUID BIOPSY MOLECULAR DEVICE WITHIN A BIOSENSOR TECHNOLOGY CLINICAL VALIDATION FRAMEWORK

2025

Conference Publication

PEARL-B: A HANDHELD DIAGNOSTIC DEVICE FOR POINT-OF-CARE EARLY ANALYSIS USING RAPID LOOP-MEDIATED ISOTHERMAL AMPLIFICATION FOR BREAST CANCER

Shrestha, Kiran, Akeruzzaman, Md, Zerin, Fatema, M., Kevin and J.A., Muhammad (2025). PEARL-B: A HANDHELD DIAGNOSTIC DEVICE FOR POINT-OF-CARE EARLY ANALYSIS USING RAPID LOOP-MEDIATED ISOTHERMAL AMPLIFICATION FOR BREAST CANCER. San Diego: Chemical and Biological Microsystems Society. doi: 10.70477/uyaq4117

PEARL-B: A HANDHELD DIAGNOSTIC DEVICE FOR POINT-OF-CARE EARLY ANALYSIS USING RAPID LOOP-MEDIATED ISOTHERMAL AMPLIFICATION FOR BREAST CANCER

2025

Journal Article

Pathophysiology, noninvasive diagnostics and emerging personalized treatments for metabolic associated liver diseases

Tantu, Milkiyas T., Farhana, Fatema Z., Haque, Farjana, Koo, Kevin M., Qiao, Liang, Ross, Allen G. and Shiddiky, Muhammad J. A. (2025). Pathophysiology, noninvasive diagnostics and emerging personalized treatments for metabolic associated liver diseases. npj Gut and Liver, 2 (1) 18, 1-15. doi: 10.1038/s44355-025-00030-2

Pathophysiology, noninvasive diagnostics and emerging personalized treatments for metabolic associated liver diseases

2025

Conference Publication

Non-invasive detection of significant prostate cancer with a 3-gene urine test

Roberts, Matthew, Koo, Kevin, Yaxley, John, Samaratunga, Hema, Jones, Andrew, Trau, Matt and Gardiner, Frank (2025). Non-invasive detection of significant prostate cancer with a 3-gene urine test. 77th Annual Scientific Meeting of the Urological-Society-of-Australia-and-New Zealand, Perth, WA Australia, 1-4 March 2025. Chichester, West Sussex, United Kingdom: Wiley.

Non-invasive detection of significant prostate cancer with a 3-gene urine test

2025

Journal Article

Enhancing electrochemical biosensing of circulating nucleic acids at the electrode-biomolecule-electrolyte interfaces

Koo, Kevin M., Farhana, Fatema Zerin, Ross, Allen G. and Shiddiky, Muhammad J. A. (2025). Enhancing electrochemical biosensing of circulating nucleic acids at the electrode-biomolecule-electrolyte interfaces. Analytical Chemistry, 97 (5), 2579-2587. doi: 10.1021/acs.analchem.4c05771

Enhancing electrochemical biosensing of circulating nucleic acids at the electrode-biomolecule-electrolyte interfaces

2025

Journal Article

Clinically boosting cancer molecular targeted radioligand therapies with innovative nanomaterials

Lim, Malcom, Simpson, Peter T., Lakhani, Sunil R., Masud, Mostafa, Puttick, Simon, Rose, Stephen, Roberts, Matthew J. and Koo, Kevin M. (2025). Clinically boosting cancer molecular targeted radioligand therapies with innovative nanomaterials. ChemNanoMat, 11 (1) e202400449, 1-14. doi: 10.1002/cnma.202400449

Clinically boosting cancer molecular targeted radioligand therapies with innovative nanomaterials

2024

Journal Article

Nanoarchitectonics of point-of-care diagnostics for sweat biomarkers analysis

Lin, Xuan, Vasanth, Arya, Ashok, Aditya, Phan, Hoang-Phuong, Koo, Kevin M., Amin, Mohammed A., Kaneti, Yusuf Valentino, Salomon, Carlos, Hossain, Md Shahriar A., Yamauchi, Yusuke and Masud, Mostafa Kamal (2024). Nanoarchitectonics of point-of-care diagnostics for sweat biomarkers analysis. Nano Materials Science, 6 (6), 647-671. doi: 10.1016/j.nanoms.2024.01.010

Nanoarchitectonics of point-of-care diagnostics for sweat biomarkers analysis

2024

Journal Article

Point-of-need mastitis pathogen biosensing in bovine milk: From academic sample preparation novelty to industry prototype field testing

Fitzpatrick, Kira J., Rohlf, Hayden J., Phillips, Grant, Macaulay, R. Bruce, Anderson, Will, Price, Rochelle, Wood, Caitlin, James, Ameh, Langhorne, Charlotte, te Brake, Bill, Gibson, Justine S. and Koo, Kevin M. (2024). Point-of-need mastitis pathogen biosensing in bovine milk: From academic sample preparation novelty to industry prototype field testing. Talanta, 277 126424, 1-9. doi: 10.1016/j.talanta.2024.126424

Point-of-need mastitis pathogen biosensing in bovine milk: From academic sample preparation novelty to industry prototype field testing

2024

Journal Article

Cancer‐on‐chip and integrative tumor microenvironment sensor technologies for progressing precision radiotherapy

Dey, Shuvashis, Kinoshita, Masaki, Puttick, Simon, Rose, Stephen, Trau, Matt, Roberts, Matthew J. and Koo, Kevin M. (2024). Cancer‐on‐chip and integrative tumor microenvironment sensor technologies for progressing precision radiotherapy. Advanced Sensor Research, 3 (7) 2300193, 1-16. doi: 10.1002/adsr.202300193

Cancer‐on‐chip and integrative tumor microenvironment sensor technologies for progressing precision radiotherapy

2023

Journal Article

Design and analytical evaluation of a rapid plasma screening assay for circulating human papillomavirus DNA via thermostable enzyme chemistries

Jaradi, Binny, Das, Tulika and Koo, Kevin M. (2023). Design and analytical evaluation of a rapid plasma screening assay for circulating human papillomavirus DNA via thermostable enzyme chemistries. Analytical Chemistry, 95 (29), 11172-11180. doi: 10.1021/acs.analchem.3c02528

Design and analytical evaluation of a rapid plasma screening assay for circulating human papillomavirus DNA via thermostable enzyme chemistries

2023

Journal Article

Multifunctional hybrid nanozymes for magnetic enrichment and bioelectrocatalytic sensing of circulating tumor RNA during minimal residual disease monitoring

Koo, Kevin M. (2023). Multifunctional hybrid nanozymes for magnetic enrichment and bioelectrocatalytic sensing of circulating tumor RNA during minimal residual disease monitoring. Catalysts, 13 (1) 178, 1-10. doi: 10.3390/catal13010178

Multifunctional hybrid nanozymes for magnetic enrichment and bioelectrocatalytic sensing of circulating tumor RNA during minimal residual disease monitoring

2023

Journal Article

Nanophotonic immunoarray with electrochemically roughened surfaces for handheld detection of secreted PD-L1 to predict immuno-oncology efficacy

Dey, Shuvashis, Koo, Kevin M., Ahmed, Emtiaz and Trau, Matt (2023). Nanophotonic immunoarray with electrochemically roughened surfaces for handheld detection of secreted PD-L1 to predict immuno-oncology efficacy. Lab on a Chip, 23 (15), 3443-3452. doi: 10.1039/d3lc00523b

Nanophotonic immunoarray with electrochemically roughened surfaces for handheld detection of secreted PD-L1 to predict immuno-oncology efficacy

2022

Journal Article

Exquisitely platinum-sensitive triple-negative breast cancer, time for BRCA methylation testing?

Tan, Tira J., Fink, J. Lynn, Tay, Timothy K., Jaradi, Binny, Stone, Nathan, Waring, Paul, Koo, Kevin M., Tan, Puay Hoon, Tan, Daniel S. and Dent, Rebecca A. (2022). Exquisitely platinum-sensitive triple-negative breast cancer, time for BRCA methylation testing?. JCO Precision Oncology, 6 (6) e2200309, e2200309. doi: 10.1200/po.22.00309

Exquisitely platinum-sensitive triple-negative breast cancer, time for BRCA methylation testing?

2022

Journal Article

Tetraplex immunophenotyping of cell surface proteomes via synthesized plasmonic nanotags and portable raman spectroscopy

Wang, Jing, Koo, Kevin M. and Trau, Matt (2022). Tetraplex immunophenotyping of cell surface proteomes via synthesized plasmonic nanotags and portable raman spectroscopy. Analytical Chemistry, 94 (43), 14906-14916. doi: 10.1021/acs.analchem.2c02262

Tetraplex immunophenotyping of cell surface proteomes via synthesized plasmonic nanotags and portable raman spectroscopy

2022

Journal Article

Harnessing gene fusion-derived neoantigens for ‘cold’ breast and prostate tumor immunotherapy

Velaga, Ravi, Koo, Kevin M. and Mainwaring, Paul N. (2022). Harnessing gene fusion-derived neoantigens for ‘cold’ breast and prostate tumor immunotherapy. Immunotherapy, 14 (14), 1165-1179. doi: 10.2217/imt-2022-0081

Harnessing gene fusion-derived neoantigens for ‘cold’ breast and prostate tumor immunotherapy