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2026 Journal Article Plasma and subcutaneous interstitial fluid vancomycin and gentamicin concentrations in three patients undergoing open abdominal aortic aneurysm repairRyan, Rochelle, Jarrett, Paul, Lassig-Smith, Melissa, Wallis, Steven C., van Zundert, Andre, Ordonez, Jenny, Won, Hayoung, Lipman, Jeffrey, Hernandez-Mitre, Maria Patricia and Roberts, Jason A. (2026). Plasma and subcutaneous interstitial fluid vancomycin and gentamicin concentrations in three patients undergoing open abdominal aortic aneurysm repair. International Journal of Antimicrobial Agents, 67 (6) 107796, 107796. doi: 10.1016/j.ijantimicag.2026.107796 |
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2026 Journal Article Nimodipine dosing and pharmacokinetic variability in subarachnoid hemorrhage patientsBellapart, Judith, Hernández-Mitre, María Patricia, Wu, Xiaolin, Wallis, Steven C., Smith, Melissa-Lassig, Stuart, Janine, Fourie, Cheryl, Livermore, Amelia and Roberts, Jason A. (2026). Nimodipine dosing and pharmacokinetic variability in subarachnoid hemorrhage patients. Journal of Clinical Neuroscience, 147 111940, 111940. doi: 10.1016/j.jocn.2026.111940 |
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2026 Journal Article Population pharmacokinetics of cefazolin and metronidazole in patients undergoing elective colorectal surgeryRyan, Rochelle, McDonald, Scott, Wallis, Steven C, van Zundert, Andre, Wu, Xiolin, Won, Hayoung, Lipman, Jeffrey, Hernandez-Mitre, Maria Patricia and Roberts, Jason A. (2026). Population pharmacokinetics of cefazolin and metronidazole in patients undergoing elective colorectal surgery. International Journal of Antimicrobial Agents, 67 (5) 107742, 107742-5. doi: 10.1016/j.ijantimicag.2026.107742 |
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2026 Journal Article Population pharmacokinetics of polymyxin B in critically ill patients with multidrug-resistant (MDR) Acinetobacter baumannii and Pseudomonas aeruginosa infectionsZamri, Puteri Juanita, Wölky, Saskia A., Hernandez-Mitre, Maria P., Liu, Xin, Hasan, M. Shahnaz, Shariff, Izyani Md, Sulaiman, Helmi, Wallis, Steven C., Sumi, Chandra Datta, Parker, Suzanne L., Sime, Fekade Bruck, Roberts, Jason A. and Abdul-Aziz, Mohd Hafiz (2026). Population pharmacokinetics of polymyxin B in critically ill patients with multidrug-resistant (MDR) Acinetobacter baumannii and Pseudomonas aeruginosa infections. International Journal of Antimicrobial Agents 107816, 107816. doi: 10.1016/j.ijantimicag.2026.107816 |
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2026 Journal Article A pharmacokinetic/pharmacodynamic analysis of intravenous tranexamic acid in adult patients undergoing elective total hip arthroplasty (ORACLE)Gurunathan, Usha, Medcalf, Robert L., Chiang, Lily, Liu, Zikou, Liu, Xin, Keragala, Charithani B., Hernandez-Mitre, Maria Patricia, Brady, Paul, Wallis, Steven C., Roberts, Jason A., Mullany, Daniel, Nandurkar, Harshal, Eley, Victoria and Parker, Suzanne L. (2026). A pharmacokinetic/pharmacodynamic analysis of intravenous tranexamic acid in adult patients undergoing elective total hip arthroplasty (ORACLE). British Journal of Anaesthesia, 136 (4), 1157-1165. doi: 10.1016/j.bja.2024.12.004 |
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2026 Journal Article Can Model-Informed Precision Dosing of Beta-Lactams in Critical Care Improve Clinical Outcomes?Oakley, Robert, Ulldemolins, Marta, Hernández Mitre, Maria Patricia, Colmenero, Manuel, Roberts, Natasha, Roberts, Jason, Lipman, Jeffrey and Heffernan, Aaron (2026). Can Model-Informed Precision Dosing of Beta-Lactams in Critical Care Improve Clinical Outcomes?. Chemotherapy, 1-23. doi: 10.1159/000550822 |
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2025 Journal Article A pharmacokinetic analysis of intravenous fluconazole in adult patients undergoing mechanical circulatory support device implantationCairns, Kelly A., Hernandez-Mitre, Maria Patricia, Peel, Trisha N., Abbott, Iain J., Kaye, David M., Marasco, Silvana, Daly, David, Warner, Victoria, Coldham, Anna, Pope, Jeffrey D., Schneider, Hans G, Dooley, Michael J., Liu, Xin, Roberts, Jason A. and Udy, Andrew A. (2025). A pharmacokinetic analysis of intravenous fluconazole in adult patients undergoing mechanical circulatory support device implantation. Clinical Pharmacokinetics, 65 (3), 395-404. doi: 10.1007/s40262-025-01607-z |
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2025 Journal Article Population pharmacokinetics and optimized dosing of piperacillin-tazobactam in hematological patients with febrile neutropeniaLaporte-Amargos, Julia, Ulldemolins, Marta, Hernández-Mitre, María Patricia, Roberts, Jason A., Rigo-Bonnin, Raul, Carmona-Torre, Francisco, Huguet, Maria, Puerta-Alcalde, Pedro, Arnan, Montserrat, del Pozo, Jose Luis, Torrent, Anna, García-Vidal, Carolina, Sureda, Anna, Bergas, Alba, Sastre-Escolà, Enric, Carratalà, Jordi and Gudiol, Carlota (2025). Population pharmacokinetics and optimized dosing of piperacillin-tazobactam in hematological patients with febrile neutropenia. Antimicrobial Agents and Chemotherapy, 70 (1) e01253-25, 1-13. doi: 10.1128/aac.01253-25 |
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2025 Journal Article Phase 1, randomized, double-blind, placebo-controlled, ascending single- and multiple-dose study of the safety, tolerability, and pharmacokinetics of intravenous xeruborbactam (QPX7728) in healthy adult subjectsHernandez-Mitre, Maria Patricia, Wallis, Steven C., Loutit, Jeffery S., Griffith, David C. and Roberts, Jason A. (2025). Phase 1, randomized, double-blind, placebo-controlled, ascending single- and multiple-dose study of the safety, tolerability, and pharmacokinetics of intravenous xeruborbactam (QPX7728) in healthy adult subjects. Antimicrobial Agents and Chemotherapy, 69 (10) e00784-25, 1-11. doi: 10.1128/aac.00784-25 |
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2025 Journal Article Optimizing ICU antifungal therapy: overcoming pharmacokinetic limitations with combination strategies—author's replyHernández-Mitre, María Patricia, Roberts, Jason A. and Roger, Claire (2025). Optimizing ICU antifungal therapy: overcoming pharmacokinetic limitations with combination strategies—author's reply. Intensive Care Medicine, 51 (4), 1-2. doi: 10.1007/s00134-025-07872-7 |
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2025 Journal Article Are contemporary antifungal doses sufficient for critically ill patients? Outcomes from an international, multicenter pharmacokinetics study for Screening Antifungal Exposure in Intensive Care Units—the SAFE-ICU studyRoberts, Jason A., Sime, Fekade B., Lipman, Jeffrey, Hernández-Mitre, María Patricia, Baptista, João Pedro, Brüggemann, Roger J., Darvall, Jai, De Waele, Jan J., Dimopoulos, George, Lefrant, Jean-Yves, Mat Nor, Mohd Basri, Rello, Jordi, Seoane, Leonardo, Slavin, Monica A., Valkonen, Miia, Venditti, Mario, Ceccarelli, Giancarlo, Wong, Wai Tat, Zeitlinger, Markus and Roger, Claire (2025). Are contemporary antifungal doses sufficient for critically ill patients? Outcomes from an international, multicenter pharmacokinetics study for Screening Antifungal Exposure in Intensive Care Units—the SAFE-ICU study. Intensive Care Medicine, 51 (2), 1-16. doi: 10.1007/s00134-025-07793-5 |
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2025 Journal Article Propofol and fentanyl pharmacokinetics and pharmacodynamics in extracorporeal membrane oxygenationMorales Castro, Diana, Balzani, Eleonora, Abdul-Aziz, M. Hafiz, Hernandez-Mitre, Maria Patricia, Wong, Irene, Turgeon, Julien, Tisminetzky, Manuel, Jurado-Camacho, Felipe, Morris, Idunn, Dresser, Linda, Granton, John, Uetrecht, Jack, Pang, K. Sandy, Chen, Eric, Shekar, Kiran and Fan, Eddy (2025). Propofol and fentanyl pharmacokinetics and pharmacodynamics in extracorporeal membrane oxygenation. Annals of the American Thoracic Society, 22 (1), 121-129. doi: 10.1513/annalsats.202407-795oc |
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2025 Journal Article Erratum to ‘TMPRSS2 inhibitors for the treatment of COVID-19 in adults: a systematic review and meta-analysis of randomized clinical trials of nafamostat and camostat mesylate’ [Clin Microbiol Infect (30) (2024) 743–754, (S1198743X24000557), (10.1016/j.cmi.2024.01.029)]Hernández-Mitre, María Patricia, Morpeth, Susan C., Venkatesh, Balasubramanian, Hills, Thomas E., Davis, Joshua, Mahar, Robert K., McPhee, Grace, Jones, Mark, Totterdell, James, Tong, Steven Y.C. and Roberts, Jason A. (2025). Erratum to ‘TMPRSS2 inhibitors for the treatment of COVID-19 in adults: a systematic review and meta-analysis of randomized clinical trials of nafamostat and camostat mesylate’ [Clin Microbiol Infect (30) (2024) 743–754, (S1198743X24000557), (10.1016/j.cmi.2024.01.029)]. Clinical Microbiology and Infection, 31 (1) 141, 141-141. doi: 10.1016/j.cmi.2024.08.005 |
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2024 Journal Article TMPRSS2 inhibitors for the treatment of COVID-19 in adults: a systematic review and meta-analysis of randomized clinical trials of nafamostat and camostat mesylateHernández-Mitre, María Patricia, Morpeth, Susan C., Venkatesh, Balasubramanian, Hills, Thomas E., Davis, Joshua, Mahar, Robert K., McPhee, Grace, Jones, Mark, Totterdell, James, Tong, Steven Y. C. and Roberts, Jason A. (2024). TMPRSS2 inhibitors for the treatment of COVID-19 in adults: a systematic review and meta-analysis of randomized clinical trials of nafamostat and camostat mesylate. Clinical Microbiology and Infection, 30 (6), 743-754. doi: 10.1016/j.cmi.2024.01.029 |
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2024 Journal Article Population pharmacokinetics of prophylactic cefoxitin in elective bariatric surgery patients: a prospective monocentric studyNovy, Emmanuel, Liu, Xin, Hernandez-Mitre, Maria Patricia, Belveyre, Thibaut, Scala-Bertola, Julien, Roberts, Jason A. and Parker, Suzanne L. (2024). Population pharmacokinetics of prophylactic cefoxitin in elective bariatric surgery patients: a prospective monocentric study. Anaesthesia Critical Care and Pain Medicine, 43 (3) 101376, 1-8. doi: 10.1016/j.accpm.2024.101376 |
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2023 Journal Article A phase I, randomized, double-blind, placebo-controlled, ascending single- and multiple-dose study of the pharmacokinetics, safety, and tolerability of oral ceftibuten in healthy adult subjectsHernández-Mitre, María Patricia, Wallis, Steven C., Morgan, Elizabeth E., Dudley, Michael N., Loutit, Jeffery S., Griffith, David C. and Roberts, Jason A. (2023). A phase I, randomized, double-blind, placebo-controlled, ascending single- and multiple-dose study of the pharmacokinetics, safety, and tolerability of oral ceftibuten in healthy adult subjects. Antimicrobial Agents and Chemotherapy, 68 (1) e0109923, 1-12. doi: 10.1128/aac.01099-23 |
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2023 Journal Article Stability of nafamostat in intravenous infusion solutions, human whole blood and extracted plasma: implications for clinical effectiveness studiesHernández-Mitre, María Patricia, Won, Hayoung, Wallis, Steven C., Parker, Suzanne L. and Roberts, Jason A. (2023). Stability of nafamostat in intravenous infusion solutions, human whole blood and extracted plasma: implications for clinical effectiveness studies. Bioanalysis, 15 (12), 673-681. doi: 10.4155/bio-2023-0040 |
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2023 Journal Article A protocol for an international, multicentre pharmacokinetic study for Screening Antifungal Exposure in Intensive Care Units: The SAFE-ICU studyRoberts, Jason A., Sime, Fekade, Lipman, Jeffrey, Hernández-Mitre, Maria Patricia, Baptista, João Pedro, Brüggemann, Roger J., Darvall, Jai, De Waele, Jan J., Dimopoulos, George, Lefrant, Jean-Yves, Mat Nor, Mohd Basri, Rello, Jordi, Seoane, Leonardo, Slavin, Monica A., Valkonen, Miia, Venditti, Mario, Wong, Wai Tat, Zeitlinger, Markus and Roger, Claire (2023). A protocol for an international, multicentre pharmacokinetic study for Screening Antifungal Exposure in Intensive Care Units: The SAFE-ICU study. Critical Care and Resuscitation, 25 (1), 1-5. doi: 10.1016/j.ccrj.2023.04.002 |
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2022 Journal Article Nafamostat mesylate for treatment of COVID-19 in hospitalised patients: a structured, narrative reviewHernández-Mitre, María Patricia, Tong, Steven Y. C., Denholm, Justin T., Dore, Gregory J., Bowen, Asha C., Lewin, Sharon R., Venkatesh, Balasubramanian, Hills, Thomas E., McQuilten, Zoe, Paterson, David L., Morpeth, Susan C. and Roberts, Jason A. (2022). Nafamostat mesylate for treatment of COVID-19 in hospitalised patients: a structured, narrative review. Clinical Pharmacokinetics, 61 (10), 1331-1343. doi: 10.1007/s40262-022-01170-x |
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2020 Journal Article Determination of Levetiracetam in Plasma by a Modified HPLC-UV Method and Its Pharmacokinetic ApplicationHernandez-Mitre, Maria P., Medellin-Garibay, Susanna E., Rodríguez-Leyva, Ildefonso, Rodríguez-Pinal, Cristian J., Zarazúa, Sergio, Jung-Cook, Helgi H., Parker, Suzanne L., Romano-Moreno, Silvia and del C. Milán-Segovia, Rosa (2020). Determination of Levetiracetam in Plasma by a Modified HPLC-UV Method and Its Pharmacokinetic Application. Mathews Journal of Pharmaceutical Science, 4 (1). doi: 10.30654/mjps.10004 |
