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2024

Journal Article

Differential response of placental cells to high D‐glucose and its impact on extracellular vesicle biogenesis and trafficking via small GTPase Ras‐related protein RAB‐7A

Palma, Carlos, Lai, Andrew, Scholz‐Romero, Katherin, Chittoory, Haarika, Van Haeringen, Benjamin, Carrion, Flavio, Handberg, Aase, Lappas, Martha, Lakhani, Sunil R., McCart Reed, Amy E, McIntyre, H. David, Nair, Soumyalekshmi and Salomon, Carlos (2024). Differential response of placental cells to high D‐glucose and its impact on extracellular vesicle biogenesis and trafficking via small GTPase Ras‐related protein RAB‐7A. Journal of Extracellular Biology, 3 (1) e135, e135-1. doi: 10.1002/jex2.135

Differential response of placental cells to high D‐glucose and its impact on extracellular vesicle biogenesis and trafficking via small GTPase Ras‐related protein RAB‐7A

2023

Journal Article

Chemically‐Induced Lipoprotein Breakdown for Improved Extracellular Vesicle Purification

Iannotta, Dalila, Amruta A., Lai, Andrew, Nair, Soumyalekshmi, Koifman, Na'ama, Lappas, Martha, Salomon, Carlos and Wolfram, Joy (2023). Chemically‐Induced Lipoprotein Breakdown for Improved Extracellular Vesicle Purification. Small, 20 (18) 2307240, 1-14. doi: 10.1002/smll.202307240

Chemically‐Induced Lipoprotein Breakdown for Improved Extracellular Vesicle Purification

2023

Journal Article

Extracellular vesicles as mediators of cell-cell communication in ovarian cancer and beyond – A lipids focus

Rani, Shikha, Lai, Andrew, Nair, Soumya, Sharma, Shayna, Handberg, Aase, Carrion, Flavio, Möller, Andreas and Salomon, Carlos (2023). Extracellular vesicles as mediators of cell-cell communication in ovarian cancer and beyond – A lipids focus. Cytokine and Growth Factor Reviews, 73, 52-68. doi: 10.1016/j.cytogfr.2023.06.004

Extracellular vesicles as mediators of cell-cell communication in ovarian cancer and beyond – A lipids focus

2022

Journal Article

Sucrose-based cryoprotective storage of extracellular vesicles

Walker, Sierra A., Davidovich, Irina, Yang, Yubo, Lai, Andrew, Goncalves, Jenifer Pendiuk, Deliwala, Vatsal, Busatto, Sara, Shapiro, Shane, Koifman, Na’ama, Salomon, Carlos, Talmon, Yeshayahu and Wolfram, Joy (2022). Sucrose-based cryoprotective storage of extracellular vesicles. Extracellular Vesicle, 1 100016, 1-7. doi: 10.1016/j.vesic.2022.100016

Sucrose-based cryoprotective storage of extracellular vesicles

Featured

2022

Journal Article

Peptide-based LDH5 inhibitors enter cancer cells and impair proliferation

Nadal-Bufí, Ferran, Chan, Lai Y., Mohammad, Hadi H., Mason, Jody M., Salomon, Carlos, Lai, Andrew, Thompson, Erik W., Craik, David J., Kaas, Quentin and Henriques, Sónia T. (2022). Peptide-based LDH5 inhibitors enter cancer cells and impair proliferation. Cellular and Molecular Life Sciences, 79 (12) 606, 606. doi: 10.1007/s00018-022-04633-3

Peptide-based LDH5 inhibitors enter cancer cells and impair proliferation

2022

Journal Article

A novel technique using chronic infusion of small extracellular vesicles from gestational diabetes mellitus causes glucose intolerance in pregnant mice

James-Allan, Laura B, Rosario, Frederick J, Madi, Lana, Barner, Kelsey, Nair, Soumyalekshmi, Lai, Andrew, Carrion, Flavio, Powell, Theresa L, Salomon, Carlos and Jansson, Thomas (2022). A novel technique using chronic infusion of small extracellular vesicles from gestational diabetes mellitus causes glucose intolerance in pregnant mice. Clinical Science, 136 (21), 1535-1549. doi: 10.1042/cs20220484

A novel technique using chronic infusion of small extracellular vesicles from gestational diabetes mellitus causes glucose intolerance in pregnant mice

2022

Journal Article

The impact of obesity and uncontrolled asthma during pregnancy on metabolic and inflammatory pathways

Bhaumik, Sreeparna, Lockett, Jack, Saif, Zarqa, Lai, Andrew, Salomon, Carlos, Whitehead, Jonathan P. and Clifton, Vicki L. (2022). The impact of obesity and uncontrolled asthma during pregnancy on metabolic and inflammatory pathways. Journal of Asthma, 60 (6), 1-12. doi: 10.1080/02770903.2022.2134794

The impact of obesity and uncontrolled asthma during pregnancy on metabolic and inflammatory pathways

2021

Journal Article

Extracellular vesicle-associated miRNAs are an adaptive response to gestational diabetes mellitus

Nair, Soumyalekshmi, Guanzon, Dominic, Jayabalan, Nanthini, Lai, Andrew, Scholz-Romero, Katherin, Kalita de Croft, Priyakshi, Ormazabal, Valeska, Palma, Carlos, Diaz, Emilio, McCarthy, Elizabeth A., Shub, Alexis, Miranda, Jezid, Gratacós, Eduard, Crispi, Fátima, Duncombe, Gregory, Lappas, Martha, McIntyre, H. David, Rice, Gregory and Salomon, Carlos (2021). Extracellular vesicle-associated miRNAs are an adaptive response to gestational diabetes mellitus. Journal of Translational Medicine, 19 (1) 360, 1-17. doi: 10.1186/s12967-021-02999-9

Extracellular vesicle-associated miRNAs are an adaptive response to gestational diabetes mellitus

2021

Journal Article

Caveolin‐1‐driven membrane remodelling regulates hnRNPK‐mediated exosomal microRNA sorting in cancer

Robinson, Harley, Ruelcke, Jayde E., Lewis, Amanda, Bond, Charles S., Fox, Archa H., Bharti, Vandhana, Wani, Shivangi, Cloonan, Nicole, Lai, Andrew, Margolin, David, Li, Li, Salomon, Carlos, Richards, Renée S., Farrell, Aine, Gardiner, Robert A., Parton, Robert G., Cristino, Alexandre S. and Hill, Michelle M. (2021). Caveolin‐1‐driven membrane remodelling regulates hnRNPK‐mediated exosomal microRNA sorting in cancer. Clinical and Translational Medicine, 11 (4) e381, e381. doi: 10.1002/ctm2.381

Caveolin‐1‐driven membrane remodelling regulates hnRNPK‐mediated exosomal microRNA sorting in cancer

2020

Journal Article

Anti-inflammatory effects of gallic acid in human gestational tissues in vitro

Nguyen-Ngo, Caitlyn, Salomon, Carlos, Lai, Andrew, Willcox, Jane C. and Lappas, Martha (2020). Anti-inflammatory effects of gallic acid in human gestational tissues in vitro. Reproduction, 160 (4), 561-578. doi: 10.1530/rep-20-0249

Anti-inflammatory effects of gallic acid in human gestational tissues in vitro

2020

Journal Article

miRNa signature in small extracellular vesicles and their association with platinum resistance and cancer recurrence in ovarian cancer

Alharbi, Mona, Sharma, Shayna, Guanzon, Dominic, Lai, Andrew, Zuñiga, Felipe, Shiddiky, Muhammad J.A., Yamauchi, Yusuke, Salas-Burgos, Alexis, He, Yaowu, Pejovic, Tanja, Winters, Carmen, Morgan, Terry, Perrin, Lewis, Hooper, John D. and Salomon, Carlos (2020). miRNa signature in small extracellular vesicles and their association with platinum resistance and cancer recurrence in ovarian cancer. Nanomedicine: Nanotechnology, Biology, and Medicine, 28 102207, 102207. doi: 10.1016/j.nano.2020.102207

miRNa signature in small extracellular vesicles and their association with platinum resistance and cancer recurrence in ovarian cancer

2020

Journal Article

Detection of Salivary Small Extracellular Vesicles Associated Inflammatory Cytokines Gene Methylation in Gingivitis

Han, Pingping, Lai, Andrew, Salomon, Carlos and Ivanovski, Sašo (2020). Detection of Salivary Small Extracellular Vesicles Associated Inflammatory Cytokines Gene Methylation in Gingivitis. International Journal of Molecular Sciences, 21 (15) 5273, 5273-17. doi: 10.3390/ijms21155273

Detection of Salivary Small Extracellular Vesicles Associated Inflammatory Cytokines Gene Methylation in Gingivitis

2020

Journal Article

Protein profile changes in circulating placental extracellular vesicles in term and preterm births: a longitudinal study

Menon, Ramkumar, Debnath, Chirantan, Lai, Andrew, Guanzon, Dominic, Bhatnagar, Shinjini, Kshetrapal, Pallavi, Sheller-Miller, Samantha, Salomon, Carlos and The Garbh-Ini Study team (2020). Protein profile changes in circulating placental extracellular vesicles in term and preterm births: a longitudinal study. Endocrinology, 161 (4) bqaa009. doi: 10.1210/endocr/bqaa009

Protein profile changes in circulating placental extracellular vesicles in term and preterm births: a longitudinal study

2020

Journal Article

Hypoxia-induced small extracellular vesicle proteins regulate proinflammatory cytokines and systemic blood pressure in pregnant rats

Dutta, Suchismita, Lai, Andrew, Scholz-Romero, Katherin, Shiddiky, Muhammad J. A., Yamauchi, Yusuke, Mishra, Jay S., Rice, Gregory E., Hyett, Jon, Kumar, Sathish and Salomon, Carlos (2020). Hypoxia-induced small extracellular vesicle proteins regulate proinflammatory cytokines and systemic blood pressure in pregnant rats. Clinical Science, 134 (6), 593-607. doi: 10.1042/cs20191155

Hypoxia-induced small extracellular vesicle proteins regulate proinflammatory cytokines and systemic blood pressure in pregnant rats

2020

Journal Article

Nobiletin exerts anti-diabetic and anti-inflammatory effects in an in vitro human model and in vivo murine model of gestational diabetes

Nguyen-Ngo, Caitlyn, Salomon, Carlos, Quak, Stephanie, Lai, Andrew, Willcox, Jane C and Lappas, Martha (2020). Nobiletin exerts anti-diabetic and anti-inflammatory effects in an in vitro human model and in vivo murine model of gestational diabetes. Clinical Science, 134 (6), 571-592. doi: 10.1042/cs20191099

Nobiletin exerts anti-diabetic and anti-inflammatory effects in an in vitro human model and in vivo murine model of gestational diabetes

2020

Journal Article

Regulation of glucose homeostasis by small extracellular vesicles in normal pregnancy and in gestational diabetes

James-Allan, Laura B., Rosario, Frederick J., Barner, Kelsey, Lai, Andrew, Guanzon, Dominic, McIntyre, H. David, Lappas, Martha, Powell, Theresa L., Salomon, Carlos and Jansson, Thomas (2020). Regulation of glucose homeostasis by small extracellular vesicles in normal pregnancy and in gestational diabetes. FASEB Journal, 34 (4) fj.201902522RR, 5724-5739. doi: 10.1096/fj.201902522RR

Regulation of glucose homeostasis by small extracellular vesicles in normal pregnancy and in gestational diabetes

2019

Journal Article

Downregulation of exosomal miR-192-5p and miR-204-5p in subjects with nonclassic apparent mineralocorticoid excess

Tapia-Castillo, Alejandra, Guanzon, Dominic, Palma, Carlos, Lai, Andrew, Barros, Eric, Allende, Fidel, Vecchiola, Andrea, Fardella, Carlos E., Salomón, Carlos and Carvajal, Cristian A. (2019). Downregulation of exosomal miR-192-5p and miR-204-5p in subjects with nonclassic apparent mineralocorticoid excess. Journal of Translational Medicine, 17 (1) 392, 392. doi: 10.1186/s12967-019-02143-8

Downregulation of exosomal miR-192-5p and miR-204-5p in subjects with nonclassic apparent mineralocorticoid excess

2019

Journal Article

Ovarian cancer-derived exosomes promote tumor metastasis in vivo an effect modulated by the invasiveness capacity of their originating cells

Alharbi, Mona, Lai, Andrew, Guanzon, Dominic, Palma, Carlos, Zuñiga, Felipe, Perrin, Lewis, He, Yaowu, Hooper, John D and Salomon, Carlos (2019). Ovarian cancer-derived exosomes promote tumor metastasis in vivo an effect modulated by the invasiveness capacity of their originating cells. Clinical Science, 133 (13), CS20190082-1419. doi: 10.1042/cs20190082

Ovarian cancer-derived exosomes promote tumor metastasis in vivo an effect modulated by the invasiveness capacity of their originating cells

2019

Journal Article

Quantitative proteomics by SWATH-MS of maternal plasma exosomes determine pathways associated with term and preterm birth

Menon, Ramkumar, Dixon, Christopher Luke, Sheller-Miller, Samantha, Fortunato, Stephen J., Saade, George R., Palma, Carlos, Lai, Andrew, Guanzon, Dominic and Salomon, Carlos (2019). Quantitative proteomics by SWATH-MS of maternal plasma exosomes determine pathways associated with term and preterm birth. Endocrinology, 160 (3), 639-650. doi: 10.1210/en.2018-00820

Quantitative proteomics by SWATH-MS of maternal plasma exosomes determine pathways associated with term and preterm birth

2019

Journal Article

Quantitative proteomics by SWATH-MS suggest an association between circulating exosomes and maternal metabolic changes in gestational diabetes mellitus

Jayabalan, Nanthini, Lai, Andrew, Nair, Soumyalekshmi, Guanzon, Dominic, Scholz-Romero, Katherin, Palma, Carlos, McIntyre, Harold David, Lappas, Martha and Salomon, Carlos (2019). Quantitative proteomics by SWATH-MS suggest an association between circulating exosomes and maternal metabolic changes in gestational diabetes mellitus. Proteomics, 19 (1-2) 1800164, e1800164. doi: 10.1002/pmic.201800164

Quantitative proteomics by SWATH-MS suggest an association between circulating exosomes and maternal metabolic changes in gestational diabetes mellitus